Novel AKT1-GLI3-VMP1 pathway mediates KRAS oncogene-induced autophagy in cancer cells

Journal of Biological Chemistry

Volumn 287, Issue 30, 2012, Pages 25325-25334

  Lo Ré, Andrea E ^a,b   Fernández Barrena, Maite G ^a   Almada, Luciana L ^a   Mills, Lisa D ^a   Elsawa, Sherine F ^a   Lund, George ^a   Ropolo, Alejandro ^b   Molejon, Maria I ^b   Vaccaro, Maria I ^b   Fernandez Zapico, Martin E ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; CANCER CELLS; CELLULAR CONSTITUENTS; CELLULAR PROCESS; CHROMATIN IMMUNOPRECIPITATION ASSAY; DEGRADATION PROCESS; HISTONE ACETYLTRANSFERASE P300; IN-VITRO; MOLECULAR MECHANISM; MOLECULAR NETWORKS; ONCOGENIC PATHWAYS; PROMOTER ACTIVITIES; REGULATORY MECHANISM; SIGNALING PATHWAYS; TUMOR PROMOTION;

DEGRADATION;

TRANSCRIPTION FACTORS;

HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE P300; MEMBRANE PROTEIN; PROTEIN KINASE B; PROTEIN KINASE B1; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG; VACUOLE MEMBRANE PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER CELL; CARCINOGENESIS; CHROMATIN IMMUNOPRECIPITATION; COMPLEX FORMATION; CONTROLLED STUDY; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METABOLIC REGULATION; MOUSE; NONHUMAN; ONCOGENE K RAS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; AUTOPHAGY; CHO CELLS; CRICETINAE; CRICETULUS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HELA CELLS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MEMBRANE PROTEINS; MICE; NEOPLASMS; NERVE TISSUE PROTEINS; P300-CBP TRANSCRIPTION FACTORS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS P21(RAS); RAS PROTEINS; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION;

ERINACEIDAE;

EID: 84864108090     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.370809     Document Type: Article

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