Hydrogen Peroxide alters splicing of soluble Guanylyl cyclase and selectively modulates expression of splicing regulators in human cancer cells

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Cote, Gilbert J ^b   Zhu, Wen ^b   Thomas, Anthony ^a   Martin, Emil ^a   Murad, Ferid ^c   Sharina, Iraida G ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 GUANYLATE CYCLASE; CELL PROTEIN; GUANYLATE CYCLASE; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A2; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN B1; HYDROGEN PEROXIDE; POLYPYRIMIDINE TRACT BINDING PROTEIN; POLYPYRIMIDINE TRACT BINDING PROTEIN 1; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ALPHA 1 GUANYLATE CYCLASE GENE; ALTERNATIVE RNA SPLICING; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL VIABILITY; COMPUTER MODEL; CONTROLLED STUDY; DOWN REGULATION; GENE; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; NEUROBLASTOMA; OXIDATIVE STRESS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ALTERNATIVE SPLICING; CELL LINE, TUMOR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GUANYLATE CYCLASE; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS; HUMANS; HYDROGEN PEROXIDE; NEOPLASMS; POLYPYRIMIDINE TRACT-BINDING PROTEIN; PROTEOLYSIS; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

EID: 84864105310     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041099     Document Type: Article

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