Identification of cell adhesive sequences in the N-terminal region of the laminin α2 chain

Journal of Biological Chemistry

Volumn 287, Issue 30, 2012, Pages 25111-25122

  Hozumi, Kentaro ^a   Ishikawa, Masaya ^a   Hayashi, Takemitsu ^a   Yamada, Yuji ^a   Katagiri, Fumihiko ^a   Kikkawa, Yamato ^a   Nomizu, Motoyoshi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE PEPTIDES; ACTIVE SEQUENCES; ALANINE SUBSTITUTION; BASEMENT MEMBRANE; CELL ATTACHMENTS; CELL-ADHESIVES; CELLULAR RECEPTORS; INTEGRINS; LAMININ; MOLECULAR MECHANISM; N-TERMINALS; NEURITE OUTGROWTH; PC12 CELLS; PLATE ASSAY; SOLUBLE PEPTIDES;

AMINO ACIDS; ASSAYS; CELLS; CYTOLOGY; MAMMALS; POLYSACCHARIDES; RECOMBINANT PROTEINS;

PEPTIDES;

ALANINE; EDETIC ACID; HEPARIN; LAMININ ALPHA2; LAMININ ALPHA2[117-128]; MUTANT PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 2;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CELL ADHESION; CELL SPREADING; CONTROLLED STUDY; HUMAN; HUMAN CELL; NERVE FIBER GROWTH; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; CELL ADHESION; HUMANS; INTEGRIN ALPHA2BETA1; LAMININ; MICE; PC12 CELLS; PEPTIDE MAPPING; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RATS;

EID: 84864099457     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.348151     Document Type: Article

References (46)

1. Miner, J. H. (2008) Laminins and their roles in mammals. Microsc. Res. Tech. 71, 349-356
2. Durbeej, M. (2010) Laminins. Cell Tissue Res. 339, 259-268
3. Aumailley, M., Bruckner-Tuderman, L., Carter, W. G., Deutzmann, R., Edgar, D., Ekblom, P., Engel, J., Engvall, E., Hohenester, E., Jones, J. C., Kleinman, H. K., Marinkovich, M. P., Martin, G. R., Mayer, U., Meneguzzi, G., Miner, J. H., Miyazaki, K., Patarroyo, M., Paulsson, M., Quaranta, V., Sanes, J. R., Sasaki, T., Sekiguchi, K., Sorokin, L. M., Talts, J. F., Tryggvason, K., Uitto, J., Virtanen, I., von der Mark, K., Wewer, U. M., Yamada, Y., and Yurchenco, P. D. (2005) A simplified laminin nomenclature. Matrix Biol. 24, 326-332 (Pubitemid 41021635)
4. Schéele, S., Nyström, A., Durbeej, M., Talts, J. F., Ekblom, M., and Ekblom, P. (2007) Laminin isoforms in development and disease. J. Mol. Med. 85, 825-836 (Pubitemid 47077111)
5. Colognato, H., and Yurchenco, P. D. (2000) Form and function. The laminin family of heterotrimers. Dev. Dyn. 218, 213-234 (Pubitemid 30349637)
6. Helbling-Leclerc, A., Bonne, G., and Schwartz, K. (2002) Emery-Dreifuss muscular dystrophy. Eur. J. Hum. Genet. 10, 157-161 (Pubitemid 34449711)
7. Guo, L. T., Zhang, X. U., Kuang, W., Xu, H., Liu, L. A., Vilquin, J. T., Miyagoe-Suzuki, Y., Takeda, S., Ruegg, M. A., Wewer, U. M., and Engvall, E. (2003) Laminin α2 deficiency and muscular dystrophy. Genotype-phenotype correlation in mutant mice. Neuromuscul. Disord. 13, 207-215 (Pubitemid 36279425)
8. Smirnov, S. P., McDearmon, E. L., Li, S., Ervasti, J. M., Tryggvason, K., and Yurchenco, P. D. (2002) Contributions of the LG modules and furin processing to laminin-2 functions. J. Biol. Chem. 277, 18928-18937 (Pubitemid 34952454)
9. Wizemann, H., Garbe, J. H., Friedrich, M. V., Timpl, R., Sasaki, T., and Hohenester, E. (2003) Distinct requirements for heparin and α-dystroglycan binding revealed by structure-based mutagenesis of the laminin α2 LG4-LG5 domain pair. J. Mol. Biol. 332, 635-642 (Pubitemid 37075986)
10. Colognato, H., and Yurchenco, P. D. (1999) The laminin α2 expressed by dystrophic dy(2J) mice is defective in its ability to form polymers. Curr. Biol. 9, 1327-1330
11. Tisi, D., Talts, J. F., Timpl, R., and Hohenester, E. (2000) Structure of the C-terminal laminin G-like domain pair of the laminin α2 chain harbouring binding sites for α-dystroglycan and heparin. EMBO J. 19, 1432-1440 (Pubitemid 30182150)
12. Suzuki, N., Hozumi, K., Urushibata, S., Yoshimura, T., Kikkawa, Y., Gumerson, J. D., Michele, D. E., Hoffman, M. P., Yamada, Y., and Nomizu, M. (2010) Identification of α-dystroglycan binding sequences in the laminin α2 chain LG4-5 module. Matrix Biol. 29, 143-151
13. Colognato, H., MacCarrick, M., O'Rear, J. J., and Yurchenco, P. D. (1997) The laminin α2-chain short arm mediates cell adhesion through both the α1β1 and α2β1 integrins. J. Biol. Chem. 272, 29330-29336 (Pubitemid 27498227)
14. Colognato-Pyke, H., O'Rear, J. J., Yamada, Y., Carbonetto, S., Cheng, Y. S., and Yurchenco, P. D. (1995) Mapping of network-forming, heparin-binding, and α1β1 integrin-recognition sites within the α-chain short arm of laminin-1. J. Biol. Chem. 270, 9398-9406
15. Nomizu, M., Kim, W. H., Yamamura, K., Utani, A., Song, S. Y., Otaka, A., Roller, P. P., Kleinman, H. K., and Yamada, Y. (1995) Identification of cell binding sites in the laminin α1 chain carboxyl-terminal globular domain by systematic screening of synthetic peptides. J. Biol. Chem. 270, 20583-20590
16. Nomizu, M., Kuratomi, Y., Malinda, K. M., Song, S. Y., Miyoshi, K., Otaka, A., Powell, S. K., Hoffman, M. P., Kleinman, H. K., and Yamada, Y. (1998) Cell binding sequences in mouse laminin α1 chain. J. Biol. Chem. 273, 32491-32499 (Pubitemid 28557624)
17. Suzuki, N., Nakatsuka, H., Mochizuki, M., Nishi, N., Kadoya, Y., Utani, A., Oishi, S., Fujii, N., Kleinman, H. K., and Nomizu, M. (2003) Biological activities of homologous loop regions in the laminin α chain G domains. J. Biol. Chem. 278, 45697-45705 (Pubitemid 37432712)
18. Hoffman, M. P., Engbring, J. A., Nielsen, P. K., Vargas, J., Steinberg, Z., Karmand, A. J., Nomizu, M., Yamada, Y., and Kleinman, H. K. (2001) Cell type-specific differences in glycosaminoglycans modulate the biological activity of a heparin-binding peptide (RKRLQVQLSIRT) from the G domain of the laminin α1 chain. J. Biol. Chem. 276, 22077-22085
19. Utani, A., Nomizu, M., Matsuura, H., Kato, K., Kobayashi, T., Takeda, U., Aota, S., Nielsen, P. K., and Shinkai, H. (2001) A unique sequence of the laminin α3 G domain binds to heparin and promotes cell adhesion through syndecan-2 and -4. J. Biol. Chem. 276, 28779-28788
20. Okazaki, I., Suzuki, N., Nishi, N., Utani, A., Matsuura, H., Shinkai, H., Yamashita, H., Kitagawa, Y., and Nomizu, M. (2002) Identification of biologically active sequences in the laminin α4 chain G domain. J. Biol. Chem. 277, 37070-37078
21. Suzuki, N., Ichikawa, N., Kasai, S., Yamada, M., Nishi, N., Morioka, H., Yamashita, H., Kitagawa, Y., Utani, A., Hoffman, M. P., and Nomizu, M. (2003) Syndecan binding sites in the laminin α1 chain G domain. Biochemistry 42, 12625-12633 (Pubitemid 37337553)
22. Richard, B. L., Nomizu, M., Yamada, Y., and Kleinman, H. K. (1996) Identification of synthetic peptides derived from laminin α1 and α2 chains with cell type specificity for neurite outgrowth. Exp. Cell Res. 228, 98-105 (Pubitemid 26349718)
23. Kato, K., Utani, A., Suzuki, N., Mochizuki, M., Yamada, M., Nishi, N., Matsuura, H., Shinkai, H., and Nomizu, M. (2002) Identification of neurite outgrowth promoting sites on the laminin α3 chain G domain. Biochemistry 41, 10747-10753 (Pubitemid 34971050)
24. Hoffman, M. P., Nomizu, M., Roque, E., Lee, S., Jung, D. W., Yamada, Y., and Kleinman, H. K. (1998) Laminin-1 and laminin-2 G-domain synthetic peptides bind syndecan-1 and are involved in acinar formation of a human submandibular gland cell line. J. Biol. Chem. 273, 28633-28641 (Pubitemid 28507547)
25. Song, S. Y., Nomizu, M., Yamada, Y., and Kleinman, H. K. (1997) Liver metastasis formation by laminin-1 peptide (LQVQLSIR)-adhesion selected B16-F10 melanoma cells. Int. J. Cancer 71, 436-441 (Pubitemid 27224310)
26. Kim, W. H., Nomizu, M., Song, S. Y., Tanaka, K., Kuratomi, Y., Kleinman, H. K., and Yamada, Y. (1998) Laminin-α1-chain sequence Leu-Gln-Val- Gln-Leu-Ser-Ile-Arg (LQVQLSIR) enhances murine melanoma cell metastases. Int. J. Cancer 77, 632-639 (Pubitemid 28340914)
27. Nomizu, M., Yokoyama, F., Suzuki, N., Okazaki, I., Nishi, N., Ponce, M. L., Kleinman, H. K., Yamamoto, Y., Nakagawa, S., and Mayumi, T. (2001) Identification of homologous biologically active sites on the N-terminal domain of laminin α chains. Biochemistry 40, 15310-15317 (Pubitemid 33151945)
28. Greene, L. A., and Tischler, A. S. (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. U.S.A. 73, 2424-2428
29. Hozumi, K., Suzuki, N., Nielsen, P. K., Nomizu, M., and Yamada, Y. (2006) Laminin α1 chain LG4 module promotes cell attachment through syndecans and cell spreading through integrin α2β1. J. Biol. Chem. 281, 32929-32940 (Pubitemid 46036848)
30. Mochizuki, M., Kadoya, Y., Wakabayashi, Y., Kato, K., Okazaki, I., Yamada, M., Sato, T., Sakairi, N., Nishi, N., and Nomizu, M. (2003) Laminin-1 peptide-conjugated chitosan membranes as a novel approach for cell engineering. FASEB J. 17, 875-877
31. Hozumi, K., Otagiri, D., Yamada, Y., Sasaki, A., Fujimori, C., Wakai, Y., Uchida, T., Katagiri, F., Kikkawa, Y., and Nomizu, M. (2010) Cell surface receptor-specific scaffold requirements for adhesion to laminin-derived peptide-chitosan membranes. Biomaterials 31, 3237-3243
32. Hozumi, K., Akizuki, T., Yamada, Y., Hara, T., Urushibata, S., Katagiri, F., Kikkawa, Y., and Nomizu, M. (2010) Cell adhesive peptide screening of the mouse lamininα1 chainGdomain. Arch. Biochem. Biophys. 503, 213-222
33. Urushibata, S., Hozumi, K., Ishikawa, M., Katagiri, F., Kikkawa, Y., and Nomizu, M. (2010) Identification of biologically active sequences in the laminin α2 chain G domain. Arch. Biochem. Biophys. 497, 43-54
34. Miles, A. J., Knutson, J. R., Skubitz, A. P., Furcht, L. T., McCarthy, J. B., and Fields, G. B. (1995) A peptide model of basement membrane collagen α 1 (IV) 531-543 binds the α3β1 integrin. J. Biol. Chem. 270, 29047-29050
35. Ettner, N., Göhring, W., Sasaki, T., Mann, K., and Timpl, R. (1998) The N-terminal globular domain of the laminin α1 chain binds to α1β1 and α2β1 integrins and to the heparan sulfate-containing domains of perlecan. FEBS Lett. 430, 217-221 (Pubitemid 28337916)
36. Makino, M., Okazaki, I., Kasai, S., Nishi, N., Bougaeva, M., Weeks, B. S., Otaka, A., Nielsen, P. K., Yamada, Y., and Nomizu, M. (2002) Identification of cell binding sites in the laminin α5-chain G domain. Exp. Cell Res. 277, 95-106 (Pubitemid 34948343)
37. Urushibata, S., Katagiri, F., Takaki, S., Yamada, Y., Fujimori, C., Hozumi, K., Kikkawa, Y., Kadoya, Y., and Nomizu, M. (2009) Biologically active sequences in the mouse laminin α3 chain G domain. Biochemistry 48, 10522-10532
38. Deleted in proof
39. Nakahara, H., Nomizu, M., Akiyama, S. K., Yamada, Y., Yeh, Y., and Chen, W. T. (1996) A mechanism for regulation of melanoma invasion. Ligation of α6β1 integrin by laminin G peptides. J. Biol. Chem. 271, 27221-27224 (Pubitemid 26367269)
40. Hozumi, K., Suzuki, N., Uchiyama, Y., Katagiri, F., Kikkawa, Y., and Nomizu, M. (2009) Chain-specific heparin-binding sequences in the laminin α chain LG45 modules. Biochemistry 48, 5375-5381
41. Hibino, S., Shibuya, M., Engbring, J. A., Mochizuki, M., Nomizu, M., and Kleinman, H. K. (2004) Identification of an active site on the laminin α5 chain globular domain that binds to CD44 and inhibits malignancy. Cancer Res. 64, 4810-4816 (Pubitemid 38924524)
42. Nomizu, M., Weeks, B. S., Weston, C. A., Kim, W. H., Kleinman, H. K., and Yamada, Y. (1995) Structure-activity study of a laminin α 1 chain active peptide segment Ile-Lys-Val-Ala-Val (IKVAV). FEBS Lett. 365, 227-231
43. Yamada, M., Kadoya, Y., Kasai, S., Kato, K., Mochizuki, M., Nishi, N., Watanabe, N., Kleinman, H. K., Yamada, Y., and Nomizu, M. (2002) Ile- Lys-Val-Ala-Val (IKVAV)-containing laminin α1 chain peptides form amyloid-like fibrils. FEBS Lett. 530, 48-52 (Pubitemid 35248184)
44. Kasai, S., Ohga, Y., Mochizuki, M., Nishi, N., Kadoya, Y., and Nomizu, M. (2004) Multifunctional peptide fibrils for biomedical materials. Biopolymers 76, 27-33 (Pubitemid 38344117)
45. Hussain, S. A., Carafoli, F., and Hohenester, E. (2011) Determinants of laminin polymerization revealed by the structure of the α5 chain amino-terminal region. EMBO Rep. 12, 276-282
46. Bernier, S. M., Utani, A., Sugiyama, S., Doi, T., Polistina, C., and Yamada, Y. (1995) Cloning and expression of laminin α 2 chain (M-chain) in the mouse. Matrix Biol. 14, 447-455