Chain-specific heparin-binding sequences in the laminin α chain LG45 modules

Biochemistry

Volumn 48, Issue 23, 2009, Pages 5375-5381

  Hozumi, Kentaro ^a   Suzuki, Nobuharu ^a,b   Uchiyama, Yoshihiko ^a   Katagiri, Fumihiko ^a   Kikkawa, Yamato ^a   Nomizu, Motoyoshi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SEQUENCES; BIOLOGICAL FUNCTIONS; C-TERMINUS; CELL ATTACHMENTS; DOSE-DEPENDENT; HEPARIN BINDING; LAMININ; LOOP REGIONS; N-TERMINAL; SOLID-PHASE; SYNTHETIC PEPTIDE;

AMINES; BINDING ENERGY; BINDING SITES; PEPTIDES;

POLYSACCHARIDES;

A 5G71; A 5G77; A 5G81; A 5G94; HEPARIN; LAMININ; LAMININ ALPHA LG45; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CELL ADHESION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING; DRUG MECHANISM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; CELL LINE, TUMOR; HEPARIN; HUMANS; LAMININ; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT;

EID: 67049159900     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900542u     Document Type: Article

References (41)

1. Colognato, H., and Yurchenco, P. D. (2000) Form and function: The laminin family of heterotrimers. Dev. Dyn. 218, 213-234.
2. Miner, J. H., and Yurchenco, P. D. (2004) Laminin functions in tissue morphogenesis. Annu. Rev. Cell Dev. Biol. 20, 255-284.
3. Miner, J. H., Li, C., Mudd, J. L., Go, G., and Sutherland, A. E. (2004) Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation. Development 131, 2247-2256. (Pubitemid 38877634)
4. Sasaki, T., Giltay, R., Talts, U., Timpl, R., and Talts, J. F. (2002) Expression and distribution of laminin α1 and α2 chains in embryonic and adult mouse tissues: An immunochemical approach. Exp. Cell Res. 275, 185-199.
5. Patton, B. L. (2000) Laminins of the neuromuscular system. Microsc. Res. Tech. 51, 247-261.
6. Fleischmajer, R., Kuroda, K., Utani, A., Douglas MacDonald, E., Perlish, J. S., Arikawa-Hirasawa, E., Sekiguchi, K., Sanzen, N., Timpl, R., and Yamada, Y. (2000) Differential expression of laminin α chains during proliferative and differentiation stages in a model for skin morphogenesis. Matrix Biol. 19, 637-647.
7. Hamill, K. J., and McLean, W. H. (2005) The α-3 polypeptide chain of laminin 5: Insight into wound healing responses from the study of genodermatoses. Clin. Exp. Dermatol. 30, 398-404.
8. Hallmann, R., Horn, N., Selg, M., Wendler, O., Pausch, F., and Sorokin, L. M. (2005) Expression and function of laminins in the embryonic and mature vasculature. Physiol. Rev. 85, 979-1000.
9. Petajaniemi, N., Korhonen, M., Kortesmaa, J., Tryggvason, K., Sekiguchi, K., Fujiwara, H., Sorokin, L., Thornell, L. E., Wondimu, Z., Assefa, D., Patarroyo, M., and Virtanen, I. (2002) Localization of laminin α4-chain in developing and adult human tissues. J. Histochem. Cytochem. 50, 1113-1130.
10. Kikkawa, Y., and Miner, J. H. (2006) Molecular dissection of laminin α5 in vivo reveals separable domain-specific roles in embryonic development and kidney function. Dev. Biol. 296, 265-277.
11. Miner, J. H., Cunningham, J., and Sanes, J. R. (1998) Roles for laminin in embryogenesis: Exencephaly, syndactyly, and placentopathy in mice lacking the laminin α5 chain. J. Cell Biol. 143, 1713-1723. (Pubitemid 29006514)
12. Timpl, R., Tisi, D., Talts, J. F., Andac, Z., Sasaki, T., and Hohenester, E. (2000) Structure and function of laminin LG modules. Matrix Biol. 19, 309-317. (Pubitemid 30665654)
13. Smirnov, S. P., McDearmon, E. L., Li, S., Ervasti, J. M., Tryggvason, K., and Yurchenco, P. D. (2002) Contributions of the LG modules and furin processing to laminin-2 functions. J. Biol. Chem. 277, 18928-18937.
14. Goldfinger, L. E., Jiang, L., Hopkinson, S. B., Stack, M. S., and Jones, J. C. (2000) Spatial regulation and activity modulation of plasmin by high affinity binding to the G domain of the α3 subunit of laminin-5. J. Biol. Chem. 275, 34887-34893.
15. Nguyen, B. P., Gil, S. G., and Carter, W. G. (2000) Deposition of laminin 5 by keratinocytes regulates integrin adhesion and signaling. J. Biol. Chem. 275, 31896-31907.
16. Bachy, S., Letourneur, F., and Rousselle, P. (2008) Syndecan-1 interaction with the LG4/5 domain in laminin-332 is essential for keratinocyte migration. J. Cell. Physiol. 214, 238-249.
17. Talts, J. F., Sasaki, T., Miosge, N., Gohring, W., Mann, K., Mayne, R., and Timpl, R. (2000) Structural and functional analysis of the recombinant G domain of the laminin α4 chain and its proteolytic processing in tissues. J. Biol. Chem. 275, 35192-35199.
18. Scheele, S., Falk, M., Franzen, A., Ellin, F., Ferletta, M., Lonai, P., Andersson, B., Timpl, R., Forsberg, E., and Ekblom, P. (2005) Laminin α1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly. Proc. Natl. Acad. Sci. U.S.A. 102, 1502-1506
19. Nomizu, M., Kim, W. H., Yamamura, K., Utani, A., Song, S. Y., Otaka, A., Roller, P. P., Kleinman, H. K., and Yamada, Y. (1995) Identification of cell binding sites in the laminin α1 chain carboxyl-terminal globular domain by systematic screening of synthetic peptides. J. Biol. Chem. 270, 20583-20590.
20. Nomizu, M., Kuratomi, Y., Malinda, K. M., Song, S. Y., Miyoshi, K., Otaka, A., Powell, S. K., Hoffman, M. P., Kleinman, H. K., and Yamada, Y. (1998) Cell binding sequences in mouse laminin α1 chain. J. Biol. Chem. 273, 32491-32499.
21. Nomizu, M., Kuratomi, Y., Ponce, M. L., Song, S. Y., Miyoshi, K., Otaka, A., Powell, S. K., Hoffman, M. P., Kleinman, H. K., and Yamada, Y. (2000) Cell adhesive sequences in mouse laminin β1 chain. Arch. Biochem. Biophys. 378, 311-320.
22. Nomizu, M., Kuratomi, Y., Song, S. Y., Ponce, M. L., Hoffman, M. P., Powell, S. K., Miyoshi, K., Otaka, A., Kleinman, H. K., and Yamada, Y. (1997) Identification of cell binding sequences in mouse laminin gamma1 chain by systematic peptide screening. J. Biol. Chem. 272, 32198-32205.
23. Nomizu, M., Yokoyama, F., Suzuki, N., Okazaki, I., Nishi, N., Ponce, M. L., Kleinman, H. K., Yamamoto, Y., Nakagawa, S., and Mayumi, T. (2001) Identification of homologous biologically active sites on the N-terminal domain of laminin α chains. Biochemistry 40, 15310-15317. (Pubitemid 33151945)
24. Suzuki, N., Ichikawa, N., Kasai, S., Yamada, M., Nishi, N., Morioka, H., Yamashita, H., Kitagawa, Y., Utani, A., Hoffman, M. P., and Nomizu, M. (2003) Syndecan binding sites in the laminin α1 chain G domain. Biochemistry 42, 12625-12633. (Pubitemid 37337553)
25. Hoffman, M. P., Engbring, J. A., Nielsen, P. K., Vargas, J., Steinberg, Z., Karmand, A. J., Nomizu, M., Yamada, Y., and Kleinman, H. K. (2001) Cell type-specific differences in glycosaminoglycans modulate the biological activity of a heparin-binding peptide (RKRLQVQLSIRT) from the G domain of the laminin α1 chain. J. Biol. Chem. 276, 22077-22085.
26. Hoffman, M. P., Nomizu, M., Roque, E., Lee, S., Jung, D. W., Yamada, Y., and Kleinman, H. K. (1998) Laminin-1 and laminin-2 G-domain synthetic peptides bind syndecan-1 and are involved in acinar formation of a human submandibular gland cell line. J. Biol. Chem. 273, 28633-28641.
27. Kadoya, Y., Nomizu, M., Sorokin, L. M., Yamashina, S., and Yamada, Y. (1998) Laminin α1 chain G domain peptide, RKRLQVQLSIRT, inhibits epithelial branching morphogenesis of cultured embryonic mouse submandibular gland. Dev. Dyn. 212, 394-402.
28. Kim, W. H., Nomizu, M., Song, S. Y., Tanaka, K., Kuratomi, Y., Kleinman, H. K., and Yamada, Y. (1998) Laminin-α1-chain sequence Leu-Gln-Val-Gln-Leu-Ser-Ile-Arg (LQVQLSIR) enhances murine melanoma cell metastases. Int. J. Cancer 77, 632-639. (Pubitemid 28340914)
29. Kato, K., Utani, A., Suzuki, N., Mochizuki, M., Yamada, M., Nishi, N., Matsuura, H., Shinkai, H., and Nomizu, M. (2002) Identification of neurite outgrowth promoting sites on the laminin α3 chain G domain. Biochemistry 41, 10747-10753. (Pubitemid 34971050)
30. Utani, A., Momota, Y., Endo, H., Kasuya, Y., Beck, K., Suzuki, N., Nomizu, M., and Shinkai, H. (2003) Laminin α3 LG4 module induces matrix metalloproteinase-1 through mitogen-activated protein kinase signaling. J. Biol. Chem. 278, 34483-34490.
31. Utani, A., Nomizu, M., Matsuura, H., Kato, K., Kobayashi, T., Takeda, U., Aota, S., Nielsen, P. K., and Shinkai, H. (2001) A unique sequence of the laminin α3 G domain binds toheparin and promotes cell adhesion through syndecan-2 and -4. J. Biol. Chem. 276, 28779-28788.
32. Okazaki, I., Suzuki, N., Nishi, N., Utani, A., Matsuura, H., Shinkai, H., Yamashita, H., Kitagawa, Y., and Nomizu, M. (2002) Identification of biologically active sequences in the laminin α4 chain G domain. J. Biol. Chem. 277, 37070-37078.
33. Makino, M., Okazaki, I., Kasai, S., Nishi, N., Bougaeva, M., Weeks, B. S., Otaka, A., Nielsen, P. K., Yamada, Y., and Nomizu, M. (2002) Identification of cell binding sites in the laminin α5-chain G domain. Exp. Cell Res. 277, 95-106.
34. Nielsen, P. K., Gho, Y. S., Hoffman, M. P., Watanabe, H., Makino, M., Nomizu, M., and Yamada, Y. (2000) Identification of a major heparin and cell binding site in the LG4 module of the laminin α5 chain. J. Biol. Chem. 275, 14517-14523.
35. Kadoya, Y., Mochizuki, M., Nomizu, M., Sorokin, L., and Yamashina, S. (2003) Role for laminin-α5 chain LG4 module in epithelial branching morphogenesis. Dev. Biol. 263, 153-164.
36. Momota, Y., Suzuki, N., Kasuya, Y., Kobayashi, T., Mizoguchi, M., Yokoyama, F., Nomizu, M., Shinkai, H., Iwasaki, T., and Utani, A. (2005) Laminin α3 LG4 module induces keratinocyte migration: Involvement of matrix metalloproteinase-9. J. Recept. Signal Transduction Res. 25, 1-17.
37. Suzuki, N., Nakatsuka, H., Mochizuki, M., Nishi, N., Kadoya, Y., Utani, A., Oishi, S., Fujii, N., Kleinman, H. K., and Nomizu, M. (2003) Biological activities of homologous loop regions in the laminin α chain G domains. J. Biol. Chem. 278, 45697-45705.
38. Hozumi, K., Suzuki, N., Nielsen, P. K., Nomizu, M., and Yamada, Y. (2006) Laminin α1 chain LG4 module promotes cell attachment through syndecans and cell spreading through integrin α2β1. J. Biol. Chem. 281, 32929-32940.
39. Hohenester, E., Tisi, D., Talts, J. F., and Timpl, R. (1999) The crystal structure of a laminin G-like module reveals the molecular basis of α-dystroglycan binding to laminins, perlecan, and agrin. Mol. Cell 4, 783-792.
40. Kato-Takagaki, K., Suzuki, N., Yokoyama, F., Takaki, S., Umezawa, K., Higo, J., Mochizuki, M., Kikkawa, Y., Oishi, S., Utani, A., and Nomizu, M. (2007) Cyclic peptide analysis of the biologically active loop region in the laminin α3 chain LG4 module demonstrates the importance of peptide conformation on biological activity. Biochemistry 46, 1952-1960. (Pubitemid 46272959)
41. Yokoyama, F., Suzuki, N., Haruki, M., Nishi, N., Oishi, S., Fujii, N., Utani, A., Kleinman, H. K., and Nomizu, M. (2004) Cyclic peptides from the loop region of the laminin α4 chain LG4 module show enhanced biological activity over linear peptides. Biochemistry 43, 13590-13597. (Pubitemid 39391159)