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Volumn 16, Issue 3, 2012, Pages 487-504

The relevance of liver histology to predicting clinically meaningful outcomes in nonalcoholic steatohepatitis

Author keywords

Cardiovascular morbidity; Fibrosis; Liver related mortality; Nonalcoholic steatohepatitis; Steatosis

Indexed keywords

APOPTOSIS; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; COMORBIDITY; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DISEASE COURSE; END STAGE LIVER DISEASE; ENDOPLASMIC RETICULUM STRESS; FOLLOW UP; HEPATITIS C; HISTOPATHOLOGY; HUMAN; LIVER BIOPSY; LIVER CELL; LIVER FIBROSIS; LIVER HISTOLOGY; LIVER TRANSPLANTATION; MALLORY BODY; NONALCOHOLIC FATTY LIVER; OUTCOME ASSESSMENT; OVERALL SURVIVAL; OXIDATIVE STRESS; PROGNOSIS; REVIEW; SCORING SYSTEM; SURVIVAL RATE; SURVIVAL TIME;

EID: 84864091966     PISSN: 10893261     EISSN: 15578224     Source Type: Journal    
DOI: 10.1016/j.cld.2012.05.006     Document Type: Review
Times cited : (45)

References (78)
  • 1
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity
    • Browning J.D., Szczepaniak L.S., Dobbins R., et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 2004, 40(6):1387-1395.
    • (2004) Hepatology , vol.40 , Issue.6 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3
  • 2
    • 0031913573 scopus 로고    scopus 로고
    • Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty
    • Luyckx F.H., Desaive C., Thiry A., et al. Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty. Int J Obes Relat Metab Disord 1998, 22(3):222-226.
    • (1998) Int J Obes Relat Metab Disord , vol.22 , Issue.3 , pp. 222-226
    • Luyckx, F.H.1    Desaive, C.2    Thiry, A.3
  • 3
    • 84857429228 scopus 로고    scopus 로고
    • Ethnicity and nonalcoholic fatty liver disease
    • Bambha K., Belt P., Abraham M., et al. Ethnicity and nonalcoholic fatty liver disease. Hepatology 2012, 55(3):769-780.
    • (2012) Hepatology , vol.55 , Issue.3 , pp. 769-780
    • Bambha, K.1    Belt, P.2    Abraham, M.3
  • 4
    • 78650486196 scopus 로고    scopus 로고
    • Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study
    • Williams C.D., Stengel J., Asike M.I., et al. Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study. Gastroenterology 2011, 140(1):124-131.
    • (2011) Gastroenterology , vol.140 , Issue.1 , pp. 124-131
    • Williams, C.D.1    Stengel, J.2    Asike, M.I.3
  • 5
    • 33748150370 scopus 로고    scopus 로고
    • Pathophysiology of nonalcoholic steatohepatitis
    • McCullough A.J. Pathophysiology of nonalcoholic steatohepatitis. J Clin Gastroenterol 2006, 40(Suppl 1):S17-S29.
    • (2006) J Clin Gastroenterol , vol.40 , Issue.SUPPL. 1
    • McCullough, A.J.1
  • 6
    • 80053581540 scopus 로고    scopus 로고
    • Frequency and outcomes of liver transplantation for nonalcoholic steatohepatitis in the United States
    • Charlton M.R., Burns J.M., Pedersen R.A., et al. Frequency and outcomes of liver transplantation for nonalcoholic steatohepatitis in the United States. Gastroenterology 2011, 141(4):1249-1253.
    • (2011) Gastroenterology , vol.141 , Issue.4 , pp. 1249-1253
    • Charlton, M.R.1    Burns, J.M.2    Pedersen, R.A.3
  • 7
    • 84055193440 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in non-alcoholic steatohepatitis: Growing evidence of an epidemic?
    • Hashimoto E., Tokushige K. Hepatocellular carcinoma in non-alcoholic steatohepatitis: Growing evidence of an epidemic?. Hepatol Res 2012, 42(1):1-14.
    • (2012) Hepatol Res , vol.42 , Issue.1 , pp. 1-14
    • Hashimoto, E.1    Tokushige, K.2
  • 8
    • 71249127127 scopus 로고    scopus 로고
    • Posttransplant metabolic syndrome: an epidemic waiting to happen
    • Pagadala M., Dasarathy S., Eghtesad B., et al. Posttransplant metabolic syndrome: an epidemic waiting to happen. Liver Transpl 2009, 15(12):1662-1670.
    • (2009) Liver Transpl , vol.15 , Issue.12 , pp. 1662-1670
    • Pagadala, M.1    Dasarathy, S.2    Eghtesad, B.3
  • 9
    • 77957375969 scopus 로고    scopus 로고
    • Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease
    • Targher G., Day C.P., Bonora E. Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease. N Engl J Med 2010, 363(14):1341-1350.
    • (2010) N Engl J Med , vol.363 , Issue.14 , pp. 1341-1350
    • Targher, G.1    Day, C.P.2    Bonora, E.3
  • 10
    • 56649112801 scopus 로고    scopus 로고
    • Diagnosis of nonalcoholic fatty liver disease: invasive versus noninvasive
    • Wieckowska A., Feldstein A.E. Diagnosis of nonalcoholic fatty liver disease: invasive versus noninvasive. Semin Liver Dis 2008, 28(4):386-395.
    • (2008) Semin Liver Dis , vol.28 , Issue.4 , pp. 386-395
    • Wieckowska, A.1    Feldstein, A.E.2
  • 11
    • 34249691194 scopus 로고    scopus 로고
    • Role of liver biopsy and serum markers of liver fibrosis in non-alcoholic fatty liver disease
    • viii
    • Adams L.A., Angulo P. Role of liver biopsy and serum markers of liver fibrosis in non-alcoholic fatty liver disease. Clin Liver Dis 2007, 11(1):25-35. viii.
    • (2007) Clin Liver Dis , vol.11 , Issue.1 , pp. 25-35
    • Adams, L.A.1    Angulo, P.2
  • 12
    • 18044373000 scopus 로고    scopus 로고
    • Histologic variation of grade and stage of non-alcoholic fatty liver disease in liver biopsies
    • Janiec D.J., Jacobson E.R., Freeth A., et al. Histologic variation of grade and stage of non-alcoholic fatty liver disease in liver biopsies. Obes Surg 2005, 15(4):497-501.
    • (2005) Obes Surg , vol.15 , Issue.4 , pp. 497-501
    • Janiec, D.J.1    Jacobson, E.R.2    Freeth, A.3
  • 13
    • 33750617920 scopus 로고    scopus 로고
    • Correlation of paired liver biopsies in morbidly obese patients with suspected nonalcoholic fatty liver disease
    • Merriman R.B., Ferrell L.D., Patti M.G., et al. Correlation of paired liver biopsies in morbidly obese patients with suspected nonalcoholic fatty liver disease. Hepatology 2006, 44(4):874-880.
    • (2006) Hepatology , vol.44 , Issue.4 , pp. 874-880
    • Merriman, R.B.1    Ferrell, L.D.2    Patti, M.G.3
  • 14
    • 33750606061 scopus 로고    scopus 로고
    • Long-term follow-up of patients with NAFLD and elevated liver enzymes
    • Ekstedt M., Franzen L.E., Mathiesen U.L., et al. Long-term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology 2006, 44(4):865-873.
    • (2006) Hepatology , vol.44 , Issue.4 , pp. 865-873
    • Ekstedt, M.1    Franzen, L.E.2    Mathiesen, U.L.3
  • 15
    • 0033038672 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity
    • Matteoni C.A., Younossi Z.M., Gramlich T., et al. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999, 116(6):1413-1419.
    • (1999) Gastroenterology , vol.116 , Issue.6 , pp. 1413-1419
    • Matteoni, C.A.1    Younossi, Z.M.2    Gramlich, T.3
  • 16
    • 58849134985 scopus 로고    scopus 로고
    • Long-term follow-up of patients with nonalcoholic fatty liver
    • Rafiq N., Bai C., Fang Y., et al. Long-term follow-up of patients with nonalcoholic fatty liver. Clin Gastroenterol Hepatol 2009, 7(2):234-238.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , Issue.2 , pp. 234-238
    • Rafiq, N.1    Bai, C.2    Fang, Y.3
  • 17
    • 79957521377 scopus 로고    scopus 로고
    • Pathologic criteria for nonalcoholic steatohepatitis: interprotocol agreement and ability to predict liver-related mortality
    • Younossi Z.M., Stepanova M., Rafiq N., et al. Pathologic criteria for nonalcoholic steatohepatitis: interprotocol agreement and ability to predict liver-related mortality. Hepatology 2011, 53(6):1874-1882.
    • (2011) Hepatology , vol.53 , Issue.6 , pp. 1874-1882
    • Younossi, Z.M.1    Stepanova, M.2    Rafiq, N.3
  • 18
    • 70350241227 scopus 로고    scopus 로고
    • The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years
    • Feldstein A.E., Charatcharoenwitthaya P., Treeprasertsuk S., et al. The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years. Gut 2009, 58(11):1538-1544.
    • (2009) Gut , vol.58 , Issue.11 , pp. 1538-1544
    • Feldstein, A.E.1    Charatcharoenwitthaya, P.2    Treeprasertsuk, S.3
  • 19
    • 0344099066 scopus 로고    scopus 로고
    • Prognosis of patients with a diagnosis of fatty liver-a registry-based cohort study
    • Jepsen P., Vilstrup H., Mellemkjaer L., et al. Prognosis of patients with a diagnosis of fatty liver-a registry-based cohort study. Hepatogastroenterology 2003, 50(54):2101-2104.
    • (2003) Hepatogastroenterology , vol.50 , Issue.54 , pp. 2101-2104
    • Jepsen, P.1    Vilstrup, H.2    Mellemkjaer, L.3
  • 20
    • 70350626532 scopus 로고    scopus 로고
    • Final results of a long-term, clinical follow-up in fatty liver patients
    • Dam-Larsen S., Becker U., Franzmann M.B., et al. Final results of a long-term, clinical follow-up in fatty liver patients. Scand J Gastroenterol 2009, 44(10):1236-1243.
    • (2009) Scand J Gastroenterol , vol.44 , Issue.10 , pp. 1236-1243
    • Dam-Larsen, S.1    Becker, U.2    Franzmann, M.B.3
  • 21
    • 80555136061 scopus 로고    scopus 로고
    • Meta-analysis: natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity
    • Musso G., Gambino R., Cassader M., et al. Meta-analysis: natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity. Ann Med 2011, 43(8):617-649.
    • (2011) Ann Med , vol.43 , Issue.8 , pp. 617-649
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 22
    • 0032695030 scopus 로고    scopus 로고
    • Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis
    • Angulo P., Keach J.C., Batts K.P., et al. Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatology 1999, 30(6):1356-1362.
    • (1999) Hepatology , vol.30 , Issue.6 , pp. 1356-1362
    • Angulo, P.1    Keach, J.C.2    Batts, K.P.3
  • 23
    • 11144351102 scopus 로고    scopus 로고
    • The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies
    • Adams L.A., Sanderson S., Lindor K.D., et al. The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies. J Hepatol 2005, 42(1):132-138.
    • (2005) J Hepatol , vol.42 , Issue.1 , pp. 132-138
    • Adams, L.A.1    Sanderson, S.2    Lindor, K.D.3
  • 24
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleiner D.E., Brunt E.M., Van Natta M., et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005, 41(6):1313-1321.
    • (2005) Hepatology , vol.41 , Issue.6 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3
  • 25
    • 0019152816 scopus 로고
    • Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease
    • Ludwig J., Viggiano T.R., McGill D.B., et al. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 1980, 55(7):434-438.
    • (1980) Mayo Clin Proc , vol.55 , Issue.7 , pp. 434-438
    • Ludwig, J.1    Viggiano, T.R.2    McGill, D.B.3
  • 26
    • 17044392299 scopus 로고    scopus 로고
    • Proposal for a histological scoring and grading system for non-alcoholic fatty liver disease
    • Mendler M.H., Kanel G., Govindarajan S. Proposal for a histological scoring and grading system for non-alcoholic fatty liver disease. Liver Int 2005, 25(2):294-304.
    • (2005) Liver Int , vol.25 , Issue.2 , pp. 294-304
    • Mendler, M.H.1    Kanel, G.2    Govindarajan, S.3
  • 27
    • 0033200054 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions
    • Brunt E.M., Janney C.G., Di Bisceglie A.M., et al. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 1999, 94(9):2467-2474.
    • (1999) Am J Gastroenterol , vol.94 , Issue.9 , pp. 2467-2474
    • Brunt, E.M.1    Janney, C.G.2    Di Bisceglie, A.M.3
  • 28
    • 0031844760 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: assessment of variability in pathologic interpretations
    • Younossi Z.M., Gramlich T., Liu Y.C., et al. Nonalcoholic fatty liver disease: assessment of variability in pathologic interpretations. Mod Pathol 1998, 11(6):560-565.
    • (1998) Mod Pathol , vol.11 , Issue.6 , pp. 560-565
    • Younossi, Z.M.1    Gramlich, T.2    Liu, Y.C.3
  • 29
    • 79251535913 scopus 로고    scopus 로고
    • Non-invasive diagnosis of nonalcoholic fatty liver and nonalcoholic steatohepatitis
    • Adams L.A., Feldstein A.E. Non-invasive diagnosis of nonalcoholic fatty liver and nonalcoholic steatohepatitis. J Dig Dis 2011, 12(1):10-16.
    • (2011) J Dig Dis , vol.12 , Issue.1 , pp. 10-16
    • Adams, L.A.1    Feldstein, A.E.2
  • 30
    • 33644524120 scopus 로고    scopus 로고
    • Apoptosis and necrosis in the liver: a tale of two deaths?
    • Malhi H., Gores G.J., Lemasters J.J. Apoptosis and necrosis in the liver: a tale of two deaths?. Hepatology 2006, 43(2 Suppl 1):S31-S44.
    • (2006) Hepatology , vol.43 , Issue.2 SUPPL. 1
    • Malhi, H.1    Gores, G.J.2    Lemasters, J.J.3
  • 31
    • 40949123364 scopus 로고    scopus 로고
    • Ballooned hepatocytes in steatohepatitis: the value of keratin immunohistochemistry for diagnosis
    • Lackner C., Gogg-Kamerer M., Zatloukal K., et al. Ballooned hepatocytes in steatohepatitis: the value of keratin immunohistochemistry for diagnosis. J Hepatol 2008, 48(5):821-828.
    • (2008) J Hepatol , vol.48 , Issue.5 , pp. 821-828
    • Lackner, C.1    Gogg-Kamerer, M.2    Zatloukal, K.3
  • 32
    • 79952231349 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings
    • Brunt E.M., Kleiner D.E., Wilson L.A., et al. Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings. Hepatology 2011, 53(3):810-820.
    • (2011) Hepatology , vol.53 , Issue.3 , pp. 810-820
    • Brunt, E.M.1    Kleiner, D.E.2    Wilson, L.A.3
  • 33
    • 29144492550 scopus 로고    scopus 로고
    • Interobserver variation in the histopathological assessment of nonalcoholic steatohepatitis
    • Fukusato T., Fukushima J., Shiga J., et al. Interobserver variation in the histopathological assessment of nonalcoholic steatohepatitis. Hepatol Res 2005, 33(2):122-127.
    • (2005) Hepatol Res , vol.33 , Issue.2 , pp. 122-127
    • Fukusato, T.1    Fukushima, J.2    Shiga, J.3
  • 34
    • 20444443042 scopus 로고    scopus 로고
    • Sampling variability of liver biopsy in nonalcoholic fatty liver disease
    • Ratziu V., Charlotte F., Heurtier A., et al. Sampling variability of liver biopsy in nonalcoholic fatty liver disease. Gastroenterology 2005, 128(7):1898-1906.
    • (2005) Gastroenterology , vol.128 , Issue.7 , pp. 1898-1906
    • Ratziu, V.1    Charlotte, F.2    Heurtier, A.3
  • 35
    • 34249697629 scopus 로고    scopus 로고
    • From Mallory to Mallory-Denk bodies: what, how and why?
    • Zatloukal K., French S.W., Stumptner C., et al. From Mallory to Mallory-Denk bodies: what, how and why?. Exp Cell Res 2007, 313(10):2033-2049.
    • (2007) Exp Cell Res , vol.313 , Issue.10 , pp. 2033-2049
    • Zatloukal, K.1    French, S.W.2    Stumptner, C.3
  • 36
    • 68949165995 scopus 로고    scopus 로고
    • Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity
    • Zhong B., Strnad P., Selmi C., et al. Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity. Hepatology 2009, 50(2):546-554.
    • (2009) Hepatology , vol.50 , Issue.2 , pp. 546-554
    • Zhong, B.1    Strnad, P.2    Selmi, C.3
  • 37
    • 80053142481 scopus 로고    scopus 로고
    • Mallory-Denk bodies are associated with outcomes and histologic features in patients with chronic hepatitis C
    • Rakoski M.O., Brown M.B., Fontana R.J., et al. Mallory-Denk bodies are associated with outcomes and histologic features in patients with chronic hepatitis C. Clin Gastroenterol Hepatol 2011, 9(10):902-909.e1.
    • (2011) Clin Gastroenterol Hepatol , vol.9 , Issue.10
    • Rakoski, M.O.1    Brown, M.B.2    Fontana, R.J.3
  • 38
    • 68849111162 scopus 로고    scopus 로고
    • Toward unraveling the complexity of simple epithelial keratins in human disease
    • Omary M.B., Ku N.O., Strnad P., et al. Toward unraveling the complexity of simple epithelial keratins in human disease. J Clin Invest 2009, 119(7):1794-1805.
    • (2009) J Clin Invest , vol.119 , Issue.7 , pp. 1794-1805
    • Omary, M.B.1    Ku, N.O.2    Strnad, P.3
  • 39
    • 51349094852 scopus 로고    scopus 로고
    • The genetic background modulates susceptibility to mouse liver Mallory-Denk body formation and liver injury
    • Hanada S., Strnad P., Brunt E.M., et al. The genetic background modulates susceptibility to mouse liver Mallory-Denk body formation and liver injury. Hepatology 2008, 48(3):943-952.
    • (2008) Hepatology , vol.48 , Issue.3 , pp. 943-952
    • Hanada, S.1    Strnad, P.2    Brunt, E.M.3
  • 40
    • 77949820532 scopus 로고    scopus 로고
    • Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress
    • Hanada S., Snider N.T., Brunt E.M., et al. Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress. Gastroenterology 2010, 138(4):1607-1617.
    • (2010) Gastroenterology , vol.138 , Issue.4 , pp. 1607-1617
    • Hanada, S.1    Snider, N.T.2    Brunt, E.M.3
  • 41
    • 1242296971 scopus 로고    scopus 로고
    • Pathologic features associated with fibrosis in nonalcoholic fatty liver disease
    • Gramlich T., Kleiner D.E., McCullough A.J., et al. Pathologic features associated with fibrosis in nonalcoholic fatty liver disease. Hum Pathol 2004, 35(2):196-199.
    • (2004) Hum Pathol , vol.35 , Issue.2 , pp. 196-199
    • Gramlich, T.1    Kleiner, D.E.2    McCullough, A.J.3
  • 42
    • 0242492522 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis-a long-term follow-up study: comparison with alcoholic hepatitis in ambulatory and hospitalized patients
    • Cortez-Pinto H., Baptista A., Camilo M.E., et al. Nonalcoholic steatohepatitis-a long-term follow-up study: comparison with alcoholic hepatitis in ambulatory and hospitalized patients. Dig Dis Sci 2003, 48(10):1909-1913.
    • (2003) Dig Dis Sci , vol.48 , Issue.10 , pp. 1909-1913
    • Cortez-Pinto, H.1    Baptista, A.2    Camilo, M.E.3
  • 43
    • 70350046669 scopus 로고    scopus 로고
    • Cytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: a multicenter validation study
    • Feldstein A.E., Wieckowska A., Lopez A.R., et al. Cytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: a multicenter validation study. Hepatology 2009, 50(4):1072-1078.
    • (2009) Hepatology , vol.50 , Issue.4 , pp. 1072-1078
    • Feldstein, A.E.1    Wieckowska, A.2    Lopez, A.R.3
  • 44
    • 79954567178 scopus 로고    scopus 로고
    • Cell death and nonalcoholic steatohepatitis: where is ballooning relevant?
    • Machado M.V., Cortez-Pinto H. Cell death and nonalcoholic steatohepatitis: where is ballooning relevant?. Expert Rev Gastroenterol Hepatol 2011, 5(2):213-222.
    • (2011) Expert Rev Gastroenterol Hepatol , vol.5 , Issue.2 , pp. 213-222
    • Machado, M.V.1    Cortez-Pinto, H.2
  • 45
    • 75449088414 scopus 로고    scopus 로고
    • Decreased survival of subjects with elevated liver function tests during a 28-year follow-up
    • Soderberg C., Stal P., Askling J., et al. Decreased survival of subjects with elevated liver function tests during a 28-year follow-up. Hepatology 2010, 51(2):595-602.
    • (2010) Hepatology , vol.51 , Issue.2 , pp. 595-602
    • Soderberg, C.1    Stal, P.2    Askling, J.3
  • 46
    • 22344452893 scopus 로고    scopus 로고
    • The natural history of nonalcoholic fatty liver disease: a population-based cohort study
    • Adams L.A., Lymp J.F., St Sauver J., et al. The natural history of nonalcoholic fatty liver disease: a population-based cohort study. Gastroenterology 2005, 129(1):113-121.
    • (2005) Gastroenterology , vol.129 , Issue.1 , pp. 113-121
    • Adams, L.A.1    Lymp, J.F.2    St Sauver, J.3
  • 47
    • 72949097025 scopus 로고    scopus 로고
    • Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels
    • Haring R., Wallaschofski H., Nauck M., et al. Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels. Hepatology 2009, 50(5):1403-1411.
    • (2009) Hepatology , vol.50 , Issue.5 , pp. 1403-1411
    • Haring, R.1    Wallaschofski, H.2    Nauck, M.3
  • 48
    • 79959541652 scopus 로고    scopus 로고
    • Fatty liver index and mortality: the Cremona study in the 15th year of follow-up
    • Calori G., Lattuada G., Ragogna F., et al. Fatty liver index and mortality: the Cremona study in the 15th year of follow-up. Hepatology 2011, 54(1):145-152.
    • (2011) Hepatology , vol.54 , Issue.1 , pp. 145-152
    • Calori, G.1    Lattuada, G.2    Ragogna, F.3
  • 49
    • 83755178774 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease and mortality among US adults: prospective cohort study
    • Lazo M., Hernaez R., Bonekamp S., et al. Non-alcoholic fatty liver disease and mortality among US adults: prospective cohort study. BMJ 2011, 343:d6891.
    • (2011) BMJ , vol.343
    • Lazo, M.1    Hernaez, R.2    Bonekamp, S.3
  • 50
    • 9644265298 scopus 로고    scopus 로고
    • Leptin, insulin resistance, and liver fibrosis in human nonalcoholic fatty liver disease
    • Angulo P., Alba L.M., Petrovic L.M., et al. Leptin, insulin resistance, and liver fibrosis in human nonalcoholic fatty liver disease. J Hepatol 2004, 41(6):943-949.
    • (2004) J Hepatol , vol.41 , Issue.6 , pp. 943-949
    • Angulo, P.1    Alba, L.M.2    Petrovic, L.M.3
  • 51
    • 77954424925 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease increases risk of death among patients with diabetes: a community-based cohort study
    • Adams L.A., Harmsen S., St Sauver J.L., et al. Nonalcoholic fatty liver disease increases risk of death among patients with diabetes: a community-based cohort study. Am J Gastroenterol 2010, 105(7):1567-1573.
    • (2010) Am J Gastroenterol , vol.105 , Issue.7 , pp. 1567-1573
    • Adams, L.A.1    Harmsen, S.2    St Sauver, J.L.3
  • 52
    • 0028875908 scopus 로고
    • The natural history of nonalcoholic fatty liver: a follow-up study
    • Teli M.R., James O.F., Burt A.D., et al. The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology 1995, 22(6):1714-1719.
    • (1995) Hepatology , vol.22 , Issue.6 , pp. 1714-1719
    • Teli, M.R.1    James, O.F.2    Burt, A.D.3
  • 53
    • 33645963121 scopus 로고    scopus 로고
    • Similarities and differences in outcomes of cirrhosis due to nonalcoholic steatohepatitis and hepatitis C
    • Sanyal A.J., Banas C., Sargeant C., et al. Similarities and differences in outcomes of cirrhosis due to nonalcoholic steatohepatitis and hepatitis C. Hepatology 2006, 43(4):682-689.
    • (2006) Hepatology , vol.43 , Issue.4 , pp. 682-689
    • Sanyal, A.J.1    Banas, C.2    Sargeant, C.3
  • 54
    • 58849132440 scopus 로고    scopus 로고
    • Clinical features and outcomes of cirrhosis due to non-alcoholic steatohepatitis compared with cirrhosis caused by chronic hepatitis C
    • Yatsuji S., Hashimoto E., Tobari M., et al. Clinical features and outcomes of cirrhosis due to non-alcoholic steatohepatitis compared with cirrhosis caused by chronic hepatitis C. J Gastroenterol Hepatol 2009, 24(2):248-254.
    • (2009) J Gastroenterol Hepatol , vol.24 , Issue.2 , pp. 248-254
    • Yatsuji, S.1    Hashimoto, E.2    Tobari, M.3
  • 55
    • 0043268063 scopus 로고    scopus 로고
    • Long-term outcomes of cirrhosis in nonalcoholic steatohepatitis compared with hepatitis C
    • Hui J.M., Kench J.G., Chitturi S., et al. Long-term outcomes of cirrhosis in nonalcoholic steatohepatitis compared with hepatitis C. Hepatology 2003, 38(2):420-427.
    • (2003) Hepatology , vol.38 , Issue.2 , pp. 420-427
    • Hui, J.M.1    Kench, J.G.2    Chitturi, S.3
  • 56
    • 79960549297 scopus 로고    scopus 로고
    • The natural history of nonalcoholic fatty liver disease with advanced fibrosis or cirrhosis: an international collaborative study
    • Bhala N., Angulo P., van der Poorten D., et al. The natural history of nonalcoholic fatty liver disease with advanced fibrosis or cirrhosis: an international collaborative study. Hepatology 2011, 54(4):1208-1216.
    • (2011) Hepatology , vol.54 , Issue.4 , pp. 1208-1216
    • Bhala, N.1    Angulo, P.2    van der Poorten, D.3
  • 57
    • 84861992004 scopus 로고    scopus 로고
    • The Framingham risk score and heart disease in nonalcoholic fatty liver disease
    • Treeprasertsuk S., Leverage S., Adams L.A., et al. The Framingham risk score and heart disease in nonalcoholic fatty liver disease. Liver Int 2012, 32(6):945-950.
    • (2012) Liver Int , vol.32 , Issue.6 , pp. 945-950
    • Treeprasertsuk, S.1    Leverage, S.2    Adams, L.A.3
  • 58
    • 84861329163 scopus 로고    scopus 로고
    • Independent association between nonalcoholic fatty liver disease and cardiovascular disease in the US population
    • Stepanova M., Younossi Z.M. Independent association between nonalcoholic fatty liver disease and cardiovascular disease in the US population. Clin Gastroenterol Hepatol 2012, 10(6):646-650.
    • (2012) Clin Gastroenterol Hepatol , vol.10 , Issue.6 , pp. 646-650
    • Stepanova, M.1    Younossi, Z.M.2
  • 59
    • 50549084740 scopus 로고    scopus 로고
    • Increased overall mortality and liver-related mortality in non-alcoholic fatty liver disease
    • Ong J.P., Pitts A., Younossi Z.M. Increased overall mortality and liver-related mortality in non-alcoholic fatty liver disease. J Hepatol 2008, 49(4):608-612.
    • (2008) J Hepatol , vol.49 , Issue.4 , pp. 608-612
    • Ong, J.P.1    Pitts, A.2    Younossi, Z.M.3
  • 60
    • 77954423206 scopus 로고    scopus 로고
    • Association between nonalcoholic fatty liver disease and coronary artery calcification
    • Chen C.H., Nien C.K., Yang C.C., et al. Association between nonalcoholic fatty liver disease and coronary artery calcification. Dig Dis Sci 2010, 55(6):1752-1760.
    • (2010) Dig Dis Sci , vol.55 , Issue.6 , pp. 1752-1760
    • Chen, C.H.1    Nien, C.K.2    Yang, C.C.3
  • 61
    • 80655144446 scopus 로고    scopus 로고
    • Coronary artery disease and cardiovascular outcomes in patients with non-alcoholic fatty liver disease
    • Wong V.W., Wong G.L., Yip G.W., et al. Coronary artery disease and cardiovascular outcomes in patients with non-alcoholic fatty liver disease. Gut 2011, 60(12):1721-1727.
    • (2011) Gut , vol.60 , Issue.12 , pp. 1721-1727
    • Wong, V.W.1    Wong, G.L.2    Yip, G.W.3
  • 62
    • 84859912969 scopus 로고    scopus 로고
    • Cardiovascular disease and nonalcoholic Fatty liver disease: does histologic severity matter?
    • Domanski J.P., Park S.J., Harrison S.A. Cardiovascular disease and nonalcoholic Fatty liver disease: does histologic severity matter?. J Clin Gastroenterol 2012, 46(5):427-430.
    • (2012) J Clin Gastroenterol , vol.46 , Issue.5 , pp. 427-430
    • Domanski, J.P.1    Park, S.J.2    Harrison, S.A.3
  • 63
    • 33645373311 scopus 로고    scopus 로고
    • Increased prevalence of cardiovascular disease in Type 2 diabetic patients with non-alcoholic fatty liver disease
    • Targher G., Bertolini L., Padovani R., et al. Increased prevalence of cardiovascular disease in Type 2 diabetic patients with non-alcoholic fatty liver disease. Diabet Med 2006, 23(4):403-409.
    • (2006) Diabet Med , vol.23 , Issue.4 , pp. 403-409
    • Targher, G.1    Bertolini, L.2    Padovani, R.3
  • 64
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: from steatosis to cirrhosis
    • Farrell G.C., Larter C.Z. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 2006, 43(2 Suppl 1):S99-S112.
    • (2006) Hepatology , vol.43 , Issue.2 SUPPL. 1
    • Farrell, G.C.1    Larter, C.Z.2
  • 65
    • 80053319811 scopus 로고    scopus 로고
    • Will the increased prevalence of nonalcoholic steatohepatitis (NASH) in the age of better hepatitis C virus therapy make NASH the deadlier disease?
    • Rinella M.E. Will the increased prevalence of nonalcoholic steatohepatitis (NASH) in the age of better hepatitis C virus therapy make NASH the deadlier disease?. Hepatology 2011, 54(4):1118-1120.
    • (2011) Hepatology , vol.54 , Issue.4 , pp. 1118-1120
    • Rinella, M.E.1
  • 66
    • 3242750664 scopus 로고    scopus 로고
    • Survival after liver transplantation in the United States: a disease-specific analysis of the UNOS database
    • Roberts M.S., Angus D.C., Bryce C.L., et al. Survival after liver transplantation in the United States: a disease-specific analysis of the UNOS database. Liver Transpl 2004, 10(7):886-897.
    • (2004) Liver Transpl , vol.10 , Issue.7 , pp. 886-897
    • Roberts, M.S.1    Angus, D.C.2    Bryce, C.L.3
  • 67
    • 79251488789 scopus 로고    scopus 로고
    • Metabolic syndrome in liver transplant recipients: prevalence, risk factors, and association with cardiovascular events
    • Laish I., Braun M., Mor E., et al. Metabolic syndrome in liver transplant recipients: prevalence, risk factors, and association with cardiovascular events. Liver Transpl 2011, 17(1):15-22.
    • (2011) Liver Transpl , vol.17 , Issue.1 , pp. 15-22
    • Laish, I.1    Braun, M.2    Mor, E.3
  • 68
    • 71249126103 scopus 로고    scopus 로고
    • Recurrent disease following liver transplantation for nonalcoholic steatohepatitis cirrhosis
    • Malik S.M., Devera M.E., Fontes P., et al. Recurrent disease following liver transplantation for nonalcoholic steatohepatitis cirrhosis. Liver Transpl 2009, 15(12):1843-1851.
    • (2009) Liver Transpl , vol.15 , Issue.12 , pp. 1843-1851
    • Malik, S.M.1    Devera, M.E.2    Fontes, P.3
  • 69
    • 71249149460 scopus 로고    scopus 로고
    • Outcomes of liver transplantation in patients with cirrhosis due to nonalcoholic steatohepatitis versus patients with cirrhosis due to alcoholic liver disease
    • Bhagat V., Mindikoglu A.L., Nudo C.G., et al. Outcomes of liver transplantation in patients with cirrhosis due to nonalcoholic steatohepatitis versus patients with cirrhosis due to alcoholic liver disease. Liver Transpl 2009, 15(12):1814-1820.
    • (2009) Liver Transpl , vol.15 , Issue.12 , pp. 1814-1820
    • Bhagat, V.1    Mindikoglu, A.L.2    Nudo, C.G.3
  • 70
    • 84255162259 scopus 로고    scopus 로고
    • Excellent posttransplant survival for patients with nonalcoholic steatohepatitis in the United States
    • Afzali A., Berry K., Ioannou G.N. Excellent posttransplant survival for patients with nonalcoholic steatohepatitis in the United States. Liver Transpl 2012, 18(1):29-37.
    • (2012) Liver Transpl , vol.18 , Issue.1 , pp. 29-37
    • Afzali, A.1    Berry, K.2    Ioannou, G.N.3
  • 71
    • 63349098164 scopus 로고    scopus 로고
    • Outcome after liver transplantation for NASH cirrhosis
    • Malik S.M., deVera M.E., Fontes P., et al. Outcome after liver transplantation for NASH cirrhosis. Am J Transplant 2009, 9(4):782-793.
    • (2009) Am J Transplant , vol.9 , Issue.4 , pp. 782-793
    • Malik, S.M.1    deVera, M.E.2    Fontes, P.3
  • 72
    • 79959558697 scopus 로고    scopus 로고
    • Misuse of scoring systems
    • [author reply: 370-1]
    • Brunt E.M., Kleiner D.E., Behling C., et al. Misuse of scoring systems. Hepatology 2011, 54(1):369-370. [author reply: 370-1].
    • (2011) Hepatology , vol.54 , Issue.1 , pp. 369-370
    • Brunt, E.M.1    Kleiner, D.E.2    Behling, C.3
  • 73
    • 1442355447 scopus 로고    scopus 로고
    • A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis
    • Promrat K., Lutchman G., Uwaifo G.I., et al. A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology 2004, 39(1):188-196.
    • (2004) Hepatology , vol.39 , Issue.1 , pp. 188-196
    • Promrat, K.1    Lutchman, G.2    Uwaifo, G.I.3
  • 74
    • 58949094415 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: selected practical issues in their evaluation and management
    • Vuppalanchi R., Chalasani N. Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: selected practical issues in their evaluation and management. Hepatology 2009, 49(1):306-317.
    • (2009) Hepatology , vol.49 , Issue.1 , pp. 306-317
    • Vuppalanchi, R.1    Chalasani, N.2
  • 75
    • 0022647490 scopus 로고
    • Complications following percutaneous liver biopsy. A multicentre retrospective study on 68,276 biopsies
    • Piccinino F., Sagnelli E., Pasquale G., et al. Complications following percutaneous liver biopsy. A multicentre retrospective study on 68,276 biopsies. J Hepatol 1986, 2(2):165-173.
    • (1986) J Hepatol , vol.2 , Issue.2 , pp. 165-173
    • Piccinino, F.1    Sagnelli, E.2    Pasquale, G.3
  • 76
    • 79959573040 scopus 로고    scopus 로고
    • Endpoints and clinical trial design for nonalcoholic steatohepatitis
    • Sanyal A.J., Brunt E.M., Kleiner D.E., et al. Endpoints and clinical trial design for nonalcoholic steatohepatitis. Hepatology 2011, 54(1):344-353.
    • (2011) Hepatology , vol.54 , Issue.1 , pp. 344-353
    • Sanyal, A.J.1    Brunt, E.M.2    Kleiner, D.E.3
  • 77
    • 14644444565 scopus 로고    scopus 로고
    • Fibrosis heterogeneity in nonalcoholic steatohepatitis and hepatitis C virus needle core biopsy specimens
    • Goldstein N.S., Hastah F., Galan M.V., et al. Fibrosis heterogeneity in nonalcoholic steatohepatitis and hepatitis C virus needle core biopsy specimens. Am J Clin Pathol 2005, 123(3):382-387.
    • (2005) Am J Clin Pathol , vol.123 , Issue.3 , pp. 382-387
    • Goldstein, N.S.1    Hastah, F.2    Galan, M.V.3
  • 78
    • 34249852704 scopus 로고    scopus 로고
    • Influence of liver biopsy heterogeneity and diagnosis of nonalcoholic steatohepatitis in subjects undergoing gastric bypass
    • Arun J., Jhala N., Lazenby A.J., et al. Influence of liver biopsy heterogeneity and diagnosis of nonalcoholic steatohepatitis in subjects undergoing gastric bypass. Obes Surg 2007, 17(2):155-161.
    • (2007) Obes Surg , vol.17 , Issue.2 , pp. 155-161
    • Arun, J.1    Jhala, N.2    Lazenby, A.J.3


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