Glucose and blood pressure lowering effects of Pycnogenol® are inefficient to prevent prolongation of QT interval in experimental diabetic cardiomyopathy

Pathology Research and Practice

Volumn 208, Issue 8, 2012, Pages 452-457

  Jankyova, Stanislava ^a   Kmecova, Jana ^a   Cernecka, Hana ^a   Mesarosova, Lucia ^b   Musil, Peter ^a   Brnoliakova, Zuzana ^c   Kyselovic, Jan ^a   Babal, Pavel ^d   Klimas, Jan ^a  

^a Physics and Informatics   (Slovakia)

^b University Teaching Hospital in Martin   (Slovakia)

^c INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

^d Faculty of Medicine of Comenius University and University Hospital Bratislava   (Slovakia)

Author keywords

Blood pressure; Diabetes mellitus; Pycnogenol ; QT interval

Indexed keywords

PYCNOGENOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTERY CATHETERIZATION; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DISEASE ASSOCIATION; DOSE RESPONSE; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG SCREENING; DRUG TREATMENT FAILURE; ELECTROCARDIOGRAM; GLUCOSE BLOOD LEVEL; HEART EDEMA; HEART LEFT VENTRICLE MASS; HEART MUSCLE CELL; HEART REPOLARIZATION; HYPERTENSION; IN VIVO STUDY; MALE; NONHUMAN; QT PROLONGATION; RAT; STREPTOZOCIN DIABETES; TREATMENT OUTCOME;

ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; BLOOD PRESSURE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; HEART VENTRICLES; HYPERGLYCEMIA; HYPERTROPHY, LEFT VENTRICULAR; HYPOGLYCEMIC AGENTS; LONG QT SYNDROME; MALE; MYOCYTES, CARDIAC; ORGAN SIZE; RATS; RATS, WISTAR;

EID: 84864088362     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2012.05.010     Document Type: Article

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