Hydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury

Brain Research Bulletin

Volumn 88, Issue 6, 2012, Pages 560-565

  Hou, Zonggang ^a,b   Luo, Wei ^b   Sun, Xuejun ^c   Hao, Shuyu ^b   Zhang, Ying ^b   Xu, Feifan ^b   Wang, Zhongcheng ^a   Liu, Baiyun ^b,d  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

^d The General Hospital of the Armed Police Force   (China)

Author keywords

Antioxidant; Hippocampus; Hydrogen rich saline; Neuroprotection; Oxidative stress; Traumatic brain injury

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HYDROGEN RICH SALINE; MALONALDEHYDE; SILENT INFORMATION REGULATOR PROTEIN 2; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITION; COGNITIVE DEFECT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFECT; MAZE TEST; NERVE CELL PLASTICITY; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; TRAUMATIC BRAIN INJURY;

ANIMALS; ANTIOXIDANTS; BRAIN INJURIES; BRAIN-DERIVED NEUROTROPHIC FACTOR; COGNITION DISORDERS; DRUG EVALUATION, PRECLINICAL; ESCAPE REACTION; HIPPOCAMPUS; HYDROGEN; LIPID PEROXIDATION; MALONDIALDEHYDE; MAZE LEARNING; MODELS, ANIMAL; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; OXIDATIVE STRESS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SIRTUIN 2; SODIUM CHLORIDE;

EID: 84864088071     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2012.06.006     Document Type: Article

References (40)

1. Aiguo W., Zhe Y., Gomez-Pinilla F. Vitamin E protects against oxidative damage and learning disability after mild traumatic brain injury in rats. Neurorehabilitation and Neural Repair 2010, 24:290-298.
2. Ansari M.A., Ahmad A.S., Ahmad M., Salim S., Yousuf S., Ishrat T., Islam F. Selenium protects cerebral ischemia in rat brain mitochondria. Biological Trace Element Research 2004, 101:73-86.
3. Ansari M.A., Roberts K.N., Scheff S.W. Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury. Free Radical Biology and Medicine 2008, 45:443-452.
4. Ashman T.A., Gordon W.A., Cantor J.B., Hibbard M.R. Neurobehavioral consequences of traumatic brain injury. The Mount Sinai Journal of Medicine, New York 2006, 73:999-1005.
5. Bains M., Hall E.D. Antioxidant therapies in traumatic brain and spinal cord injury. Biochimica et Biophysica Acta 2012, 1822:675-684.
6. Cai J., Kang Z., Liu K., Liu W., Li R., Zhang J.H., Luo X., Sun X. Neuroprotective effects of hydrogen saline in neonatal hypoxia-ischemia rat model. Brain Research 2009, 1256:129-137.
7. Chen H., Sun Y.P., Hu P.F., Liu W.W., Xiang H.G., Li Y., Yan R.L., Su N., Ruan C.P., Sun X.J., Wang Q. The effects of hydrogen-rich saline on the contractile and structural changes of intestine induced by ischemia-reperfusion in rats. Journal of Surgical Research 2011, 167:316-322.
8. Clausen F., Lundqvist H., Ekmark S., Lewen A., Ebendal T., Hillered L. Oxygen free radical-dependent activation of extracellular signal-regulated kinase mediates apoptosis-like cell death after traumatic brain injury. Journal of Neurotrauma 2004, 21:1168-1182.
9. Daitoku H., Hatta M., Matsuzaki H., Aratani S., Ohshima T., Miyagishi M., Nakajima T., Fukamizu A. Silent information regulator 2 potentiates foxo1-mediated transcription through its deacetylase activity. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:10042-10047.
10. Dixon C.E., Lyeth B.G., Povlishock J.T., Findling R.L., Hamm R.J., Marmarou A., Young H.F., Hayes R.L. A fluid percussion model of experimental brain injury in the rat. Journal of Neurosurgery 1987, 67:110-119.
11. Drapeau E., Mayo W., Aurousseau C., Le Moal M., Piazza P.V., Abrous D.N. Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America 2003, 100:14385-14390.
12. Fujimoto S.T., Longhi L., Saatman K.E., Conte V., Stocchetti N., McIntosh T.K. Motor and cognitive function evaluation following experimental traumatic brain injury. Neuroscience and Biobehavioral Reviews 2004, 28:365-378.
13. Giese K.P. News from molecular biological studies of memory. Brain Research Bulletin 2011, 85:1.
14. Gottesfeld Z., Moore A.N., Dash P.K. Acute ethanol intake attenuates inflammatory cytokines after brain injury in rats: a possible role for corticosterone. Journal of Neurotrauma 2002, 19:317-326.
15. Gu Y., Huang C.S., Inoue T., Yamashita T., Ishida T., Kang K.M., Nakao A. Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice. Journal of Clinical Biochemistry and Nutrition 2010, 46:269-276.
16. Hall E.D., Braughler J.M. Free radicals in CNS injury. Research Publications: Association for Research in Nervous and Mental Disease 1993, 71:81-105.
17. Hall E.D., Detloff M.R., Johnson K., Kupina N.C. Peroxynitrite-mediated protein nitration and lipid peroxidation in a mouse model of traumatic brain injury. Journal of Neurotrauma 2004, 21:9-20.
18. Himanen L., Portin R., Isoniemi H., Helenius H., Kurki T., Tenovuo O. Cognitive functions in relation to MRI findings 30 years after traumatic brain injury. Brain Injury 2005, 19:93-100.
19. Li J., Wang C., Zhang J.H., Cai J.M., Cao Y.P., Sun X.J. Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress. Brain Research 2010, 1328:152-161.
20. Mao Y.F., Zheng X.F., Cai J.M., You X.M., Deng X.M., Zhang J.H., Jiang L., Sun X.J. Hydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats. Biochemical and Biophysical Research Communications 2009, 381:602-605.
21. Marnett L.J. Lipid peroxidation-DNA damage by malondialdehyde. Mutation Research 1999, 424:83-95.
22. Merenda A., Gugliotta M., Holloway R., Levasseur J.E., Alessandri B., Sun D., Bullock M.R. Validation of brain extracellular glycerol as an indicator of cellular membrane damage due to free radical activity after traumatic brain injury. Journal of Neurotrauma 2008, 25:527-537.
23. Molteni R., Wu A., Vaynman S., Ying Z., Barnard R.J., Gomez-Pinilla F. Exercise reverses the harmful effects of consumption of a high-fat diet on synaptic and behavioral plasticity associated to the action of brain-derived neurotrophic factor. Neuroscience 2004, 123:429-440.
24. Nagata K., Nakashima-Kamimura N., Mikami T., Ohsawa I., Ohta S. Consumption of molecular hydrogen prevents the stress-induced impairments in hippocampus-dependent learning tasks during chronic physical restraint in mice. Neuropsychopharmacology 2009, 34:501-508.
25. Ohsawa I., Ishikawa M., Takahashi K., Watanabe M., Nishimaki K., Yamagata K., Katsura K., Katayama Y., Asoh S., Ohta S. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nature Medicine 2007, 13:688-694.
26. Ozdemir D., Uysal N., Gonenc S., Acikgoz O., Sonmez A., Topcu A., Ozdemir N., Duman M., Semin I., Ozkan H. Effect of melatonin on brain oxidative damage induced by traumatic brain injury in immature rats. Physiological Research/Academia Scientiarum Bohemoslovaca 2005, 54:631-637.
27. Rao V., Lyketsos C. Neuropsychiatric sequelae of traumatic brain injury. Psychosomatics 2000, 41:95-103.
28. Rodgers J.T., Lerin C., Haas W., Gygi S.P., Spiegelman B.M., Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 2005, 434:113-118.
29. Salmond C.H., Chatfield D.A., Menon D.K., Pickard J.D., Sahakian B.J. Cognitive sequelae of head injury: involvement of basal forebrain and associated structures. Brain: A Journal of Neurology 2005, 128:189-200.
30. Salmond C.H., Menon D.K., Chatfield D.A., Pickard J.D., Sahakian B.J. Changes over time in cognitive and structural profiles of head injury survivors. Neuropsychologia 2006, 44:1995-1998.
31. Shao C., Roberts K.N., Markesbery W.R., Scheff S.W., Lovell M.A. Oxidative stress in head trauma in aging. Free Radical Biology and Medicine 2006, 41:77-85.
32. Sharma S., Zhuang Y., Ying Z., Wu A., Gomez-Pinilla F. Dietary curcumin supplementation counteracts reduction in levels of molecules involved in energy homeostasis after brain trauma. Neuroscience 2009, 161:1037-1044.
33. Shen L., Wang J., Liu K., Wang C., Wu H., Sun Q., Sun X., Jing H. Hydrogen-rich saline is cerebroprotective in a rat model of deep hypothermic circulatory arrest. Neurochemical Research 2011, 36:1501-1511.
34. Shingu C., Koga H., Hagiwara S., Matsumoto S., Goto K., Yokoi I., Noguchi T. Hydrogen-rich saline solution attenuates renal ischemia-reperfusion injury. Journal of Anesthesia 2010, 24:569-574.
35. Sun Q., Kang Z., Cai J., Liu W., Liu Y., Zhang J.H., Denoble P.J., Tao H., Sun X. Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats. Experimental Biology and Medicine (Maywood) 2009, 234:1212-1219.
36. Vaynman S., Ying Z., Gomez-Pinilla F. The select action of hippocampal calcium calmodulin protein kinase II in mediating exercise-enhanced cognitive function. Neuroscience 2007, 144:825-833.
37. Wu A., Ying Z., Gomez-Pinilla F. The interplay between oxidative stress and brain-derived neurotrophic factor modulates the outcome of a saturated fat diet on synaptic plasticity and cognition. European Journal of Neuroscience 2004, 19:1699-1707.
38. Wu A., Ying Z., Gomez-Pinilla F. Oxidative stress modulates Sir2alpha in rat hippocampus and cerebral cortex. European Journal of Neuroscience 2006, 23:2573-2580.
39. Wu A., Ying Z., Gomez-Pinilla F. Vitamin E protects against oxidative damage and learning disability after mild traumatic brain injury in rats. Neurorehabilitation and Neural Repair 2010, 24:290-298.
40. Zhou Y., Zheng H., Ruan F., Chen X., Zheng G., Kang M., Zhang Q., Sun X. Hydrogen-rich saline alleviates experimental noise-induced hearing loss in guinea pigs. Neuroscience 2012, 209:47-53.