Prostanoid receptor 2 signaling protects T helper 2 cells from BALB/c mice against activation-induced cell death

Journal of Biological Chemistry

Volumn 287, Issue 30, 2012, Pages 25434-25439

  Kaul, Vandana ^a   Van Kaer, Luc ^b   Das, Gobardhan ^a   Das, Jyoti ^c  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY ICGEB   (India)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF MALARIA RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION-INDUCED CELL DEATHS; AIRWAY INFLAMMATION; AUTOIMMUNE DISEASE; BALB/C MICE; ENDOPEROXIDES; G PROTEIN COUPLED RECEPTORS; IMMUNOMODULATION; INTRACELLULAR PATHOGENS; LEISHMANIA; LOW LEVEL;

CELL DEATH;

MAMMALS;

GRANZYME B; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STRAIN DIFFERENCE; T LYMPHOCYTE ACTIVATION; TH2 CELL;

ANIMALS; CELL DEATH; CELL SURVIVAL; DINOPROSTONE; FEMALE; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; PROSTAGLANDIN ENDOPEROXIDES; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; SIGNAL TRANSDUCTION; TH2 CELLS;

ANIMALIA; MUS;

EID: 84864081612     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C111.324707     Document Type: Article

References (27)

1. Gorczynski, R. M. (1982) Nature of resistance to leishmaniasis in experimental rodents. Dev. Comp. Immunol. 6, 199-207
2. Launois, P., Himmelrich, H., Tacchini-Cottier, F., Milon, G., and Louis, J. A. (1999) New insight into the mechanisms underlying Th2 cell development and susceptibility to Leishmania major in BALB/c mice. Microbes Infect. 1, 59-64 (Pubitemid 29364913)
3. Brewer, J. P., Kisselgof, A. B., and Martin, T. R. (1999) Genetic variability in pulmonary physiological, cellular, and antibody responses to antigen in mice. Am. J. Respir. Crit. Care Med. 160, 1150-1156 (Pubitemid 29487453)
4. Bajénoff, M., Wurtz, O., and Guerder, S. (2002) Repeated antigen exposure is necessary for the differentiation, but not the initial proliferation, of naive CD4+ T cells. J. Immunol. 168, 1723-1729 (Pubitemid 34135770)
5. Bird, J. J., Brown, D. R., Mullen, A. C., Moskowitz, N. H., Mahowald, M. A., Sider, J. R., Gajewski, T. F., Wang, C. R., and Reiner, S. L. (1998) Helper T cell differentiation is controlled by the cell cycle. Immunity 9, 229-237 (Pubitemid 28400036)
6. Gett, A. V., and Hodgkin, P. D. (1998) Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation. Proc. Natl. Acad. Sci. U.S.A. 95, 9488-9493 (Pubitemid 28506258)
7. Grogan, J. L., Mohrs, M., Harmon, B., Lacy, D. A., Sedat, J. W., and Locksley, R. M. (2001) Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. Immunity 14, 205-215 (Pubitemid 32289286)
8. Azar, S. T., Tamim, H., Beyhum, H. N., Habbal, M. Z., and Almawi, W. Y. (1999) Type I (insulin-dependent) diabetes is a Th1- and Th2-mediated autoimmune disease. Clin. Diagn. Lab. Immunol. 6, 306-310 (Pubitemid 29226796)
9. Biedermann, T., Röcken, M., and Carballido, J. M. (2004) TH1 and TH2 lymphocyte development and regulation of TH cell-mediated immune responses of the skin. J. Investig. Dermatol. Symp. Proc. 9, 5-14 (Pubitemid 38096191)
10. Mazzarella, G., Bianco, A., Catena, E., De Palma, R., and Abbate, G. F. (2000) Th1/Th2 lymphocyte polarization in asthma. Allergy 55, Suppl. 61, 6-9 (Pubitemid 30430371)
11. Wangoo, A., Sparer, T., Brown, I. N., Snewin, V. A., Janssen, R., Thole, J., Cook, H. T., Shaw, R. J., and Young, D. B. (2001) Contribution of Th1 and Th2 cells to protection and pathology in experimental models of granulomatous lung disease. J. Immunol. 166, 3432-3439 (Pubitemid 33117346)
12. + T cells are dispensable for T cell-dependent allergic airway inflammation. Nat. Med. 12, 1345-1346; author reply 1347
13. Chatelain, R., Varkila, K., and Coffman, R. L. (1992) IL-4 induces a Th2 response in Leishmania major-infected mice. J. Immunol. 148, 1182-1187
14. Radwanska, M., Cutler, A. J., Hoving, J. C., Magez, S., Holscher, C., Bohms, A., Arendse, B., Kirsch, R., Hunig, T., Alexander, J., Kaye, P., and Brombacher, F. (2007) Deletion of IL-4Rα on CD4 T cells renders BALB/c mice resistant to Leishmania major infection. PLoS Pathog. 3, e68
15. Scott, P. (1991) IFN-γ modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. J. Immunol. 147, 3149-3155
16. Devadas, S., Das, J., Liu, C., Zhang, L., Roberts, A. I., Pan, Z., Moore, P. A., Das, G., and Shi, Y. (2006) Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cells. Immunity 25, 237-247 (Pubitemid 44224145)
17. Spellberg, B., and Edwards, J. E., Jr. (2001) Type 1/Type 2 immunity in infectious diseases. Clin. Infect. Dis. 32, 76-102 (Pubitemid 32150953)
18. Lanzavecchia, A., and Sallusto, F. (2000) Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells. Science 290, 92-97
19. Green, D. R., Droin, N., and Pinkoski, M. (2003) Activation-induced cell death in T cells. Immunol. Rev. 193, 70-81 (Pubitemid 36688041)
20. Kim, R., Emi, M., and Tanabe, K. (2006) Cancer immunosuppression and autoimmune disease: beyond immunosuppressive networks for tumor immunity. Immunology 119, 254-264 (Pubitemid 44401644)
21. Dempke, W., Rie, C., Grothey, A., and Schmoll, H. J. (2001) Cyclooxygenase- 2: a novel target for cancer chemotherapy? J. Cancer Res. Clin. Oncol. 127, 411-417 (Pubitemid 32524357)
22. Fedyk, E. R., and Phipps, R. P. (1996) Prostaglandin E2 receptors of the EP2 and EP4 subtypes regulate activation and differentiation of mouse B lymphocytes to IgE-secreting cells. Proc. Natl. Acad. Sci. U.S.A. 93, 10978-10983 (Pubitemid 26333103)
23. Hata, A. N., and Breyer, R. M. (2004) Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation. Pharmacol. Ther. 103, 147-166 (Pubitemid 39209041)
24. + T lymphoblasts. J. Immunol. 154, 1041-1047
25. Kapsenberg, M. L., Hilkens, C. M., Wierenga, E. A., and Kalinski, P. (1999) The paradigm of type 1 and type 2 antigen-presenting cells: implications for atopic allergy. Clin. Exp. Allergy 29, Suppl. 2, 33-36 (Pubitemid 29314660)
26. 2 EP1 receptor. Trends Pharmacol. Sci. 27, 458-460
27. Wilson, R. J., Rhodes, S. A., Wood, R. L., Shield, V. J., Noel, L. S., Gray, D. W., and Giles, H. (2004) Functional pharmacology of human prostanoid EP2 and EP4 receptors. Eur. J. Pharmacol. 501, 49-58 (Pubitemid 39298936)