Characterization of a novel activated Ran GTPase mutant and its ability to induce cellular transformation

Journal of Biological Chemistry

Volumn 287, Issue 30, 2012, Pages 24955-24966

  Milano, Shawn K ^a   Kwon, Woojin ^a   Pereira, Ryan ^a   Antonyak, Marc A ^a   Cerione, Richard A ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOCARCINOMA CELLS; CALCIUM BINDING; CELL INVASION; CELLULAR TRANSFORMATION; CONTROL VECTOR; EXTRACELLULAR-REGULATED KINASE; FIBER ASSEMBLIES; GROWTH FACTOR; GTP BINDING; GTPASES; MATRICELLULAR PROTEIN; MICROARRAY ANALYSIS; MITOTIC SPINDLE; N-TERMINALS; NUCLEAR ENVELOPE FORMATION; NUCLEOCYTOPLASMIC TRANSPORT; ONCOGENIC TRANSFORMATION; OVER-EXPRESSION; SIGNALING PATHWAYS; TUMOR FORMATION; WILD TYPES;

ANCHORAGES (FOUNDATIONS); ENZYMES; FIBROBLASTS; GENE ENCODING;

CELL CULTURE;

BINDING PROTEIN; GROWTH FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; RAN PROTEIN; SECRETED MODULAR CALCIUM BINDING PROTEIN 2; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CELL GROWTH; CELL INVASION; CELL STRAIN 3T3; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; HYDROLYSIS; MICROARRAY ANALYSIS; MUTANT; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; WILD TYPE;

AMINO ACID SUBSTITUTION; ANIMALS; CALCIUM-BINDING PROTEINS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; ENZYME ACTIVATION; HUMANS; MICE; MUTATION, MISSENSE; NIH 3T3 CELLS; RAN GTP-BINDING PROTEIN;

MUS; PEREIRA;

EID: 84864080094     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.306514     Document Type: Article

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