Cell-penetrating TAT peptide in drug delivery systems: Proteolytic stability requirements

Drug Delivery

Volumn 18, Issue 5, 2011, Pages 377-384

  Koren, Erez ^a   Apte, Anjali ^a   Sawant, Rupa R ^a   Grunwald, Jacob ^a   Torchilin, Vladimir P ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Drug delivery; PEG PE; polymeric micelles; proteolytic cleavage; steric shielding; TAT peptide

Indexed keywords

ARGININE; CELL PENETRATING PEPTIDE; DOXORUBICIN; LIPOSOME; MACROGOL; PHOSPHATIDYLETHANOLAMINE; THREONYLALANYLTHREONINE PEPTIDE; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CELL INTERACTION; CONJUGATE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; FEMALE; FLUORESCENCE ANALYSIS; FLUORESCENCE MICROSCOPY; HELA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MICELLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN STABILITY;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; CELL-PENETRATING PEPTIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HELA CELLS; HUMANS; MELANOMA, EXPERIMENTAL; MICE; NEOPLASMS; PHOSPHATIDYLETHANOLAMINES; POLYETHYLENE GLYCOLS; PROTEIN STABILITY; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TRYPSIN;

EID: 79958217723     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2011.567310     Document Type: Article

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