Synthesis and functional evaluation of chiral dendrimer-triamine- coordinated Gd complexes as highly sensitive MRI contrast agents

Tetrahedron Letters

Volumn 53, Issue 34, 2012, Pages 4580-4583

  Miyake, Yuka ^a   Kimura, Yu ^a   Ishikawa, Syungo ^a   Tsujita, Hiroshi ^a   Miura, Hiroki ^a   Narazaki, Michiko ^a   Matsuda, Tetsuya ^a   Tabata, Yasuhiko ^b   Yano, Tetsuya ^c   Toshimitsu, Akio ^a   Kondo, Teruyuki ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c CANON INC   (Japan)

Author keywords

Chiral dendrimer; Drug design; Gadolinium; MRI contrast agent; Pharmacokinetics

Indexed keywords

AMINE; BOVINE SERUM ALBUMIN; DENDRIMER; GADOLINIUM; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; PENTETIC ACID;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BLOOD VESSEL; CHIRALITY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DESIGN; DRUG EXCRETION; DRUG SCREENING; DRUG SYNTHESIS; ISOMER; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; QUANTITATIVE ANALYSIS; QUARTZ CRYSTAL MICROBALANCE;

BOVINAE; MUS;

EID: 84864064516     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2012.06.072     Document Type: Article

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