Enantioselective synthesis of trans -dihydrobenzofurans via primary amine-thiourea organocatalyzed intramolecular michael addition

Journal of Organic Chemistry

Volumn 77, Issue 14, 2012, Pages 6208-6214

  Lu, Aidang ^a   Hu, Keling ^a   Wang, Youming ^a   Song, Haibin ^a   Zhou, Zhenghong ^a   Fang, Jianxin ^a   Tang, Chuchi ^a  

^a NANKAI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROBENZOFURANS; ENANTIOSELECTIVE SYNTHESIS; HIGH TEMPERATURE; HIGH YIELD; IN-SITU; INTRAMOLECULAR MICHAEL ADDITION;

ADDITION REACTIONS; ENANTIOSELECTIVITY; ORGANIC COMPOUNDS; SCAFFOLDS;

THIOUREAS;

(R,R) 1,2 DIPHENYLETHYLAMINE; 1 ((2R,3S) 2,3 DIHYDRO 3 (NITROMETHYL) BENZOFURAN 2 YL) ETHANONE; 1((1S,2R) 1,2 DIHYDRO 1 (NITROMETHYL) NAPHTHO [2,1 B] FURAN 2 YL) ETHANONE; 1((2R,3S) 2,3 DIHYDRO 5 METHOXY 3 (NITROMETHYL) BENZOFURAN 2 YL) ETHANONE; 1((2R,3S) 2,3 DIHYDRO 5 METHYL 3 (NITROMETHYL) BENZOFURAN 2 YL) ETHANONE; 1((2R,3S) 2,3 DIHYDRO 5 NITRO 3 (NITROMETHYL) BENZOFURAN 2 YL) ETHANONE; 1((2R,3S) 2,3 DIHYDRO 6 METHYL 3 (NITROMETHYL) BENZOFURAN 2 YL) ETHANONE; 1((2R,3S) 2,3 DIHYDRO 7 METHOXY 3 (NITROMETHYL) BENZOFURAN 2 YL ETHANONE; 1((2R,3S) 2,3 DIHYDRO 7 METHOXY 3 (NITROMETHYL) BENZOFURAN 2 YL) ETHANONE; 1((2R,3S) 2,3 DIHYDRO 7 METHYL 3 (NITROMETHYL) BENZOFURAN 2 YL) ETHANONE; 1((2R,3S) 5 BROMO 2,3 DIHYDRO 3 (NITROMETHYL) BENZOFURAN 2 YL) ETHANONE; 1((2R,3S) 5 CHLORO 2,3 DIHYDRO 3 (NITROMETHYL) BENZOFURAN 2 YL) ETHANONE; 1((2R,3S) 5 FLUORO 2,3 DIHYDRO 3 (NITROMETHYL) BENZOFURAN 2 YL) ETHANONE; AMINE; DIHYDROBENZOFURAN DERIVATIVE; THIOUREA; TRANS DIHYDROBENZOFURAN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; ENANTIOSELECTIVITY; HIGH TEMPERATURE; ISOMERIZATION; MICHAEL ADDITION;

AMINES; BENZOFURANS; MOLECULAR STRUCTURE; STEREOISOMERISM; THIOUREA;

EID: 84864053226     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo301006e     Document Type: Article

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