Estimation of crystallinity of trehalose dihydrate microspheres by usage of terahertz time-domain spectroscopy

Journal of Pharmaceutical Sciences

Volumn 101, Issue 9, 2012, Pages 3465-3472

  Takeuchi, Issei ^a   Tomoda, Keishiro ^a   Nakajima, Takehisa ^a   Terada, Hiroshi ^a   Kuroda, Hideki ^b   Makino, Kimiko ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b Otsuka Electronics Co Ltd   (Japan)

Author keywords

Amorphous; Analysis; Anhydrous trehalose; Crystalline water; Crystallinity; Microspheres; Spray drying; Terahertz time domain spectroscopy; Trehalose dihydrate; Water vapor

Indexed keywords

MICROSPHERE; TREHALOSE; TREHALOSE DIHYDRATE MICROSPHERE; UNCLASSIFIED DRUG;

ARTICLE; CALIBRATION; CRYSTALLIZATION; SPRAY DRYING; TERAHERTZ SPECTROSCOPY;

EID: 84864036919     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23147     Document Type: Article

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