Rosiglitazone treatment reduces hippocampal neuronal damage possibly through alleviating oxidative stress in chronic cerebral hypoperfusion

Neurochemistry International

Volumn 61, Issue 3, 2012, Pages 287-290

  Sayan Ozacmak, Hale ^a   Ozacmak, Veysel Haktan ^a   Barut, Figen ^a   Jakubowska Dogru, Ewa ^b  

^a Zonguldak Karaelmas Universitesi Tip Fakultesi   (Turkey)

^b MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Chronic cerebral hypoperfusion; Oxidative stress; Rosiglitazone

Indexed keywords

MALONALDEHYDE; ROSIGLITAZONE; ROSVEL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; CHRONIC CEREBRAL HYPOPERFUSION; COMMON CAROTID ARTERY; CONTROLLED STUDY; MALE; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PERFUSION; PRIORITY JOURNAL; RAT; TREATMENT DURATION;

ANIMALS; CHRONIC DISEASE; HIPPOCAMPUS; MALE; NEURONS; OXIDATIVE STRESS; RATS; RATS, WISTAR; THIAZOLIDINEDIONES;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 84864033701     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.05.011     Document Type: Article

References (15)

1. A. Annahazi, E. Mracsko, Z. Sule, E. Karg, B. Penke, F. Bari, and E. Farkas Pre-treatment and post-treatment with alpha-tocopherol attenuates hippocampal neuronal damage in experimental cerebral hypoperfusion Eur. J. Pharmacol. 571 2007 120 128 (Pubitemid 47379685)
2. T. Breidert, J. Callebert, M.T. Heneka, G. Landreth, J.M. Launay, and E.C. Hirsch Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease J. Neurochem. 82 2002 615 624 (Pubitemid 34831499)
3. E. Farkas, A. Institoris, F. Domoki, A. Mihaly, P.G. Luiten, and F. Bari Diazoxide and dimethyl sulphoxide prevent cerebral hypoperfusion-related learning dysfunction and brain damage after carotid artery occlusion Brain Res. 1008 2004 252 260 (Pubitemid 38624056)
4. K. Fuenzalida, R. Quintanilla, P. Ramos, D. Piderit, R.A. Fuentealba, G. Martinez, N.C. Inestrosa, and M. Bronfman Peroxisome proliferator-activated receptor gamma up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis J. Biol. Chem. 282 2007 37006 37015
5. Hong, S., Xin, Y., Haiqin, W., Guilian, Z., Ru, Z., Shuqin, Z., Huqing, W., Li, Y., Yun, D., 2011. The PPARγ agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and oxidative stress following pilocarpine-induced status epilepticus. Neurol. Sci. (Sep 14, 2011, Epub ahead of print, PMID:21915647).
6. S. Kasparová, V. Brezová, M. Valko, J. Horecký, V. Mlynárik, T. Liptaj, O. Vancová, O. Ulicná, and D. Dobrota Study of the oxidative stress in a rat model of chronic brain hypoperfusion Neurochem. Int. 46 2005 601 611 (Pubitemid 40614863)
7. W.A. Pedersen, P.J. McMillan, J.J. Kulstad, J.B. Leverenz, S. Craft, and G.R. Haynatzki Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice Exp. Neurol. 199 2006 265 273 (Pubitemid 43928978)
8. Y. Peng, S. Xu, G. Chen, L. Wang, Y. Feng, and X. Wang l-3-n-Butylphthalide improves cognitive impairment induced by chronic cerebral hypoperfusion in rats J. Pharmacol. Exp. Ther. 321 2007 902 910 (Pubitemid 46762705)
9. H. Sain, B. Sharma, A.S. Jaggi, and N. Singh Pharmacological investigations on potential of peroxisome proliferator-activated receptor-gamma agonists in hyperhomocysteinemia-induced vascular dementia in rats Neuroscience 192 2011 322 333
10. H. Sayan-Ozacmak, V.H. Ozacmak, F. Barut, and E. Jakubowska-Dogru Neuroprotective efficacy of the peroxisome proliferator-activated receptor-γ ligand in chronic cerebral hypoperfusion Curr. Neurovasc. Res. 8 2011 190 199
11. J.C. Strum, R. Shehee, D. Virley, J. Richardson, M. Mattie, P. Selley, S. Ghosh, C. Nock, A. Saunders, and A. Roses Rosiglitazone induces mitochondrial biogenesis in mouse brain J. Alzheimers Dis. 11 2007 45 51 (Pubitemid 46376708)
12. S. Sundararajan, J.L. Gamboa, N.A. Victor, E.W. Wanderi, W.D. Lust, and G.E. Landreth Peroxisome proliferator-activated receptor-gamma ligands reduce inflammation and infarction size in transient focal ischemia Neuroscience 130 2005 685 696 (Pubitemid 39601441)
13. K. Tureyen, R. Kapadia, K.K. Bowen, I. Satriotomo, J. Liang, D.L. Feinstein, and R. Vemuganti Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents J. Neurochem. 101 2007 41 56 (Pubitemid 46426485)
14. J.H. Yi, S.W. Park, N. Brooks, B.T. Lang, and R. Vemuganti PPARgamma agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms Brain Res. 1244 2008 164 172
15. G.L. Zhang, J.P. Deng, B.H. Wang, Z.W. Zhao, J. Li, L. Gao, B.L. Liu, J.R. Xong, X.D. Guo, Z.Q. Yan, and G.D. Gao Gypenosides improve cognitive impairment induced by chronic cerebral hypoperfusion in rats by suppressing oxidative stress and astrocytic activation Behav. Pharmacol. 22 2011 633 644