Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo

Infection and Immunity

Volumn 80, Issue 8, 2012, Pages 2601-2607

  van Gennip, Maria ^a   Christensen, Louise Dahl ^a   Alhede, Morten ^a,b   Qvortrup, Klaus ^a   Jensen, Peter Østrup ^b   Høiby, Niels ^a,b   Givskov, Michael ^a,c   Bjarnsholt, Thomas ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Rigshospitalet   (Denmark)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

RHAMNOLIPID;

ARTICLE; BACTERIAL GROWTH; BIOFILM; CELL INTERACTION; CONFOCAL LASER MICROSCOPY; FEMALE; HOST PATHOGEN INTERACTION; IN VIVO STUDY; INNATE IMMUNITY; MOUSE; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SCANNING ELECTRON MICROSCOPY; SILICONE PROSTHESIS;

ANIMALS; BIOFILMS; DNA, BACTERIAL; FEMALE; GENES, BACTERIAL; GLYCOLIPIDS; HOST-PATHOGEN INTERACTIONS; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MUTATION; NEUTROPHILS; PHAGOCYTOSIS; PROSTHESIS-RELATED INFECTIONS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SILICONES;

EID: 84864024867     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.06215-11     Document Type: Article

References (42)

1. Alhede M, et al. 2009. Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes. Microbiology 155, 3500-3508.
2. Alhede M, et al. 2011. Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm. PLoS One 6, e27943. doi, 10.1371/journal.pone.0027943.
3. Allesen-Holm M, et al. 2006. A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms. Mol. Microbiol. 59, 1114-1128.
4. Arciola CR, An YH, Campoccia D, Donati ME, Montanaro L. 2005. Etiology of implant orthopedic infections, a survey on 1027 clinical isolates. Int. J. Artif. Organs 28, 1091-1100.
5. Beiter K, et al. 2006. An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps. Curr. Biol. 16, 401-407.
6. Bjarnsholt T, et al. 2005. Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections. Microbiology 151, 3873-3880.
7. Bjarnsholt T, et al. 2005. Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorumsensing dependent. Microbiology 151, 373-383.
8. Bjarnsholt T, et al. 2009. Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients. Pediatr. Pulmonol. 44, 547-558.
9. Bjarnsholt T, et al. 2010. In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect. Nat. Protoc. 5, 282-293.
10. Borregaard N. 2010. Neutrophils, from marrow to microbes. Immunity 33, 657-670.
11. Brinkmann V, et al. 2004. Neutrophil extracellular traps kill bacteria. Science 303, 1532-1535.
12. Buchanan JT, et al. 2006. DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps. Curr. Biol. 16, 396-400.
13. Buret A, Ward KH, Olson ME, Costerton JW. 1991. An in vivo model to study the pathobiology of infectious biofilms on biomaterial surfaces. J. Biomed. Mater. Res. 25, 865-874.
14. Christensen LD, et al. 2007. Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model. Microbiology 153, 2312-2320
15. Christensen LD, et al. 2012. Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model. J. Antimicrob. Chemother. 67, 1198-1206.
16. Costerton JW. 1999. Introduction to biofilm. Int. J. Antimicrob. Agents 11, 217-221. 15a.Council of Europe. 2 December 2005 (amended). European convention for the protection of vertebrate animals used for experimental and other scientific purposes. Strasbourg, France. http, //conventions.coe.int/Treaty /en/Treaties/html/123.htm.
17. Cox G, Crossley J, Xing Z. 1995. Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo. Am. J. Respir. Cell Mol. Biol. 12, 232-237.
18. Dasgupta MK. 2002. Biofilms and infection in dialysis patients. Semin. Dial. 15, 338-346.
19. Davies DG, et al. 1998. The involvement of cell-to-cell signals in the development of a bacterial biofilm. Science 280, 295-298.
20. Dougherty SH. 1988. Pathobiology of infection in prosthetic devices. Rev. Infect. Dis. 10, 1102-1117.
21. Ermert D, et al. 2009. Mouse neutrophil extracellular traps in microbial infections. J. Innate Immun. 1, 181-193.
22. Gjødsbøl K, et al. 2006. Multiple bacterial species reside in chronic wounds, a longitudinal study. Int. Wound J. 3, 225-231.
23. Høiby N. 1974. Pseudomonas aeruginosa infection in cystic fibrosis. Relationship between mucoid strains of Pseudomonas aeruginosa and the humoral immune response. Acta Pathol. Microbiol. Scand. B Microbiol. Immunol. 82, 551-558.
24. Jensen PØ, et al. 2007. Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa. Microbiology 153, 1329-1338.
25. Jesaitis AJ, et al. 2003. Compromised host defense on Pseudomonas aeruginosa biofilms, characterization of neutrophil and biofilm interactions. J. Immunol. 171, 4329-4339.
26. Kirketerp-Møller K. 2008. Distribution, organization, and ecology of bacteria in chronic wounds. J. Clin. Microbiol. 46, 2717-2722.
27. Koch B, Jensen LE, Nybroe O. 2001. A panel of Tn7-based vectors for insertion of the gfp marker gene or for delivery of cloned DNA into Gramnegative bacteria at a neutral chromosomal site. J. Microbiol. Methods 45, 187-195.
28. Kohler T, Guanella R, Carlet J, van Delden C. 2010. Quorum sensingdependent virulence during Pseudomonas aeruginosa colonisation and pneumonia in mechanically ventilated patients. Thorax 65, 703-710.
29. Kownatzki R, Tümmler B, Döring G. 1987. Rhamnolipid of Pseudomonas aeruginosa in sputum of cystic fibrosis patients. Lancet i, 1026-1027.
30. Krautgartner WD, et al. 2010. Fibrin mimics neutrophil extracellular traps in SEM. Ultrastruct. Pathol. 34, 226-231.
31. Kumoh H. 1996. Pathogenesis and management of bacterial biofilms in the urinary tract. J. Infect. Chemother. 2, 18-28.
32. MacRae EK, Pryzwansky KE, Cooney MH, Spitznagel JK. 1980. Scanning electron microscopic observations of early stages of phagocytosis of E. coli by human neutrophils. Cell Tissue Res. 209, 65-70.
33. Pamp SJ, Tolker-Nielsen T. 2007. Multiple roles of biosurfactants in structural biofilm development by Pseudomonas aeruginosa. J. Bacteriol. 189, 2531-2539.
34. Segal AW. 2005. How neutrophils kill microbes. Annu. Rev. Immunol. 23, 197-223.
35. Singh PK, et al. 2000. Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms. Nature 407, 762-764.
36. Thomsen TR, et al. 2010. The bacteriology of chronic venous leg ulcer examined by culture-independent molecular methods. Wound Repair Regen. 18, 38-49.
37. van Gennip M, et al. 2009. Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes. APMIS 117, 537-546.
38. von Eiff C, Jansen B, Kohnen W, Becker K. 2005. Infections associated with medical devices, pathogenesis, management and prophylaxis. Drugs 65, 179-214.
39. Walker TS, et al. 2005. Enhanced Pseudomonas aeruginosa biofilm development mediated by human neutrophils. Infect. Immun. 73, 3693-3701.
40. Ward KH, Olson ME, Lam K, Costerton JW. 1992. Mechanism of persistent infection associated with peritoneal implants. J. Med. Microbiol. 36, 406-413.
41. Whitchurch CB, Tolker-Nielsen T, Ragas PC, Mattick JS. 2002. Extracellular DNA required for bacterial biofilm formation. Science 295, 1487.
42. Extracellular DNA required for bacterial biofilm formation