Measurement error robustness of a closed-loop minimal sampling method for HIV therapy switching

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

Volumn , Issue , 2011, Pages 116-119

  Cardozo, E Fabian ^a   Zurakowski, Ryan ^a  

^a University of Delaware   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOSED-LOOP; DATA-DRIVEN; HIV THERAPY; LOG-NORMAL; NUMBER OF SAMPLES; OPTIMAL SWITCHING; PATIENT MODELS; RISK REDUCTIONS; SAMPLING METHOD; SCHEDULING METHODS; SIMULATED PATIENTS; SWITCHING TIME; THERAPEUTIC BENEFITS; VIRAL LOAD; VIRAL LOAD MEASUREMENTS;

ALGORITHMS; COMPUTER SIMULATION; HOSPITAL DATA PROCESSING; OPTIMIZATION;

SWITCHING;

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BIOLOGICAL MARKER;

ALGORITHM; ARTICLE; BIOLOGICAL MODEL; COMPUTER ASSISTED DRUG THERAPY; COMPUTER SIMULATION; EQUIPMENT DESIGN; EQUIPMENT FAILURE; FEEDBACK SYSTEM; HUMAN; METHODOLOGY; SAMPLE SIZE; STATISTICAL ANALYSIS; TREATMENT OUTCOME; VIRUS LOAD;

ALGORITHMS; ANTI-HIV AGENTS; BIOLOGICAL MARKERS; COMPUTER SIMULATION; DATA INTERPRETATION, STATISTICAL; DRUG THERAPY, COMPUTER-ASSISTED; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FEEDBACK; HUMANS; MODELS, BIOLOGICAL; SAMPLE SIZE; TREATMENT OUTCOME; VIRAL LOAD;

EID: 80455143807     PISSN: 1557170X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/IEMBS.2011.6089910     Document Type: Conference Paper

References (9)

1. R. Luo, L. Cannon, J. Hernandez, M. J. Piovoso, and R. Zurakowski, "Controlling the evolution of resistance," Journal of Process Control, vol. 21, no. 3, pp. 367 - 378, 2011. [Online]. Available: http://www. sciencedirect.com/science/article/B6V4N-51PH81K-1/2/ f3bebc3b84b714bae5f1477b2defd1d0
2. R. Luo, M. Piovoso, and R. Zurakowski, "A generalized multi-strain model of hiv evolution with implications for drug-resistance management," in American Control Conference, 2009. ACC '09., 2009, pp. 2295 -2300.
3. R. Luo and R. Zurakowski, "A new strategy to decrease risk of resistance emerging during therapy switching in hiv treatment," in American Control Conference, 2008, 2008, pp. 2112 -2117.
4. R. Zurakowski and D. Wodarz, "Treatment interruptions to decrease risk of resistance emerging during therapy switching in hiv treatment," in Decision and Control, 2007 46th IEEE Conference on, 2007, pp. 5174 -5179.
5. E. Rosero-Garcia and R. Zurakowski, "Closed-loop minimal sampling method for determining viral-load minima during switching," in American Control Conference (ACC), 2010, 302010-july2 2010, pp. 460 -461.
6. R. Zurakowski, M. Churgin, C. Perez, and M. Rodriguez, "Approximate-model closed-loop minimal sampling method for HIV viral-load minima detection," Proceedings of the American Control Conference, p. (to appear), apr 2011.
7. L. Perrin, J. M. Pawlotsky, M. Bouvier-Alias, C. Sarrazin, S. Zeuzem, and G. Colucci, "Multicenter performance evaluation of a new TaqMan PCR assay for monitoring human immunodeficiency virus RNA load." Journal of clinical microbiology, vol. 44, no. 12, pp. 4371-4375, dec 2006.
8. R. Luo, M. J. Piovoso, J. Martinez-Picado, and R. Zurakowski, "Hiv model parameter estimates from clinical data including reservoir dynamics," PLoS One, Submitted.
9. L. Ruiz, G. Carcelain, J. Martínez-Picado, S. Frost, S. Marfil, R. Paredes, J. Romeu, E. Ferrer, K. Morales-Lopetegi, B. Autran, and B. Clotet, "HIV dynamics and T-cell immunity after three structured treatment interruptions in chronic HIV-1 infection," AIDS, vol. 15, no. 9, pp. F19-27, jun 2001.