Resveratrol protects against acute chemotherapy toxicity induced by doxorubicin in rat erythrocyte and plasma

Journal of Physiology and Pharmacology

Volumn 63, Issue 3, 2012, Pages 293-301

  Hamlaoui, Sonia ^a   Mokni, M ^a   Limam, N ^a   Carrier, A ^b   Limam, F ^c   Amri, M ^a   Marzouki, L ^a   Aouani, E ^c  

^a FACULTÉ DES SCIENCES DE TUNIS   (Tunisia)

^b INSERM   (France)

^c CENTRE DE BIOTECHNOLOGIE DE BORJ CÉDRIA   (Tunisia)

Author keywords

Antioxidant enzymes; Doxorubicin; Erythrocyte; Malondialdehyde; Oxidative stress; Plasma; Resveratrol

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CALCIUM; CATALASE; DOXORUBICIN; HYDROGEN PEROXIDE; IRON; MALONALDEHYDE; PEROXIDASE; RESVERATROL; SUPEROXIDE DISMUTASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD SAMPLING; CELL LEVEL; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; ENZYME ACTIVITY; ERYTHROCYTE; FEMALE; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PLASMA; PROTEIN BLOOD LEVEL; PROTEIN CARBONYLATION; RAT;

ALANINE TRANSAMINASE; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIOXIDANTS; ASPARTATE AMINOTRANSFERASES; CALCIUM; CATALASE; DOXORUBICIN; ERYTHROCYTES; FEMALE; HYDROGEN PEROXIDE; IRON; LIPID PEROXIDATION; MALONDIALDEHYDE; OXIDATIVE STRESS; PROTEIN CARBONYLATION; RATS; RATS, WISTAR; STILBENES; SUPEROXIDE DISMUTASE;

EID: 84864006639     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Singal PK, Iliskovic N. Doxorubicin-induced cardiomyopathy. New Engl J Med 1998; 339: 900-905.
2. Buzdar AU, Marcus C, Smith TL, Blumenschein GR. Early and delayed clinical cardiotoxicity of doxorubicin. Cancer 1985; 55: 2761-2765.
3. Singal PK, Deally CM, Weinberg LE. Subcellular effects of adriamycin in the heart: a concise review. J Mol Cell Cardiol 1987; 19: 817-828.
4. Sinha BK, Katki AG, Batist G, Cowan KH, Myers CE. Adriamycin stimulated hydroxyl radical formation in human breast tumor cells. Biochem Pharmacol 1987; 36: 793-796.
5. Sinha BK, Katki AG, Batist G, Cowan KH, Myers CE. Differential formation of hydroxyl radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: Implications for the mechanism of action. Biochemistry 1987; 26: 3776-3781.
6. Rosen GM, Halpern HJ. Spin trapping biologically generated free radicals: correlating formation with cellular injury. Method Enzymol 1990; 18: 611-621.
7. Singal PK, Siveski-Iliskovic N, Hill M, Thomas TP, Li T. Combination therapy with probucol prevents adriamycin-induced cardiomyopathy. J Mol Cell Cardiol 1995; 27: 1055-1063.
8. Doroshow JH, Locker GY, Myers CE. Enzymatic defences of the mouse heart against reactive oxygen metabolites: alterations produced by doxorubicin. J Clin Invest 1980; 65: 128-135.
9. Floreani M, Napoli E, Quintieri L, Palatini P. Oral administration of trans-resveratrol to guinea pigs increases cardiac DT-diaphorase and catalase activities, and protects isolated atria from menadione toxicity. Life Sci 2003; 72: 2741-2750.
10. Bradamante S, Barenghi L, Piccinini F, et al. Resveratrol provides late-phase cardioprotection by means of a NO and adenosine-mediated mechanism. Eur J Pharmacol 2003; 465: 115-123.
11. Hsieh TC, Juan GZ, Arzynkiewicz ZD, Wu JM. Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21 (WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2. Cancer Res 1999; 59: 2596-2601.
12. Bastianetto S, Zheng WH, Quirion R. Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide related toxicity in cultured hippocampal neurons. Br J Pharmacol 2000; 131: 711-720.
13. Bertelli A, Giovannini L, Giannessi D, et al. Anti-platelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995; 17: 1-3.
14. Belguendouz L, Fremont L, Gozzelino MT. Interaction of transresveratrol with plasma lipoproteins. Biochem Pharmacol 1998; 55: 811-816.
15. Huang C, Ma WY, Goranson A, Dong Z. Resveratrol suppress cell transformation and induces apoptosis through a P53-dependent pathway. Carcinogenesis 1999; 20: 237-242.
16. Jang M, Cai L, Udeani GO, et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997; 275: 218-220.
17. Gehm BD, McAndrews JM, Chien PY, Jameson JL. Resveratrol, a polyphenolic compound found in grapes and wine is an agonist for the oestrogen receptor. Proc Natl Acad Sci USA 1997; 94: 14138-14143.
18. Mokni M, Limam F, Elkahoui S, Amri M, Aouani E. Strong cardioprotective effect of resveratrol, a red wine polyphenol, on isolated rat hearts after ischemia/reperfusion injury. Arch Biochem Biophys 2007; 457: 1-6.
19. Fremont L. Biological effects of resveratrol. Life Sci 2000; 66: 663-673.
20. Rotondo S, Rajtar G, Manarini S, et al. Effect of transresveratrol, a natural polyphenolic compound, on human polymorphonuclear leukocyte function. Br J Pharmacol 1998; 123: 1691-1699.
21. Sener G, Toklu HZ, Sehirli AO, Velioglu-Ogunc A, Cetinel S, Gedik N. Protective effects of resveratrol against acetaminophen-induced toxicity in mice. Hepatol Res 2006; 35: 62-68.
22. Kasdallah-Grissa A, Mornagui B, Aouani E, et al. Resveratrol, a red wine polyphenol, attenuates ethanol-induced oxidative stress in rat liver. Life Sci 2007; 80: 1033-1039.
23. Bujanda L, Garcya-Barcina M, Gutierrez-de Juan V, et al. Effect of resveratrol on alcohol-induced mortality and liver lesions in mice. BMC Gastroenterol 2006; 6: 35.
24. Guide for the Care and the Use of Laboratory Animals. National Research Council. Washington D.C., National Academy Press, 1996.
25. Draper HH, Hadley M. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol 1990; 186: 421-431.
26. Levine LR, Garland D, Oliver CN, et al. Determination of carbonyl content in oxidatively modified proteins. Method Enzymol 1990; 186: 464-478.
27. Ohnishi ST, Barr JK. A simple method of quantitating protein using the biuret and phenol reagent. Anal Biochem 1978; 86: 193-200.
28. Aebi H. Catalase in vitro. Methods Enzymol 1984; 105: 121-126.
29. Chance B, Maehly AC. Assay of catalases and peroxidases. Methods Enzymol 1955; 2: 764-817.
30. Misra HP, Fridovich I. The role of superoxide anion in autoxidation of epinephrine and a simple assay for SOD. J Biol Chem 1972; 247: 3170-3175.
31. Leardi A, Caraglia M, Selleri C, et al. Desferioxamine increases iron depletion and apoptosis induced by ara-C of human myeloid leukaemic cells. Brit J Haematol 1998; 102: 746-752.
32. Kakinuma K, Yamaguchi T, Kaneda M, Shimada K, Tomita Y, Chance B. A determination of H2O2 release by the treatment of human blood polymorphonuclear leukocytes with myristate. J Biochem 1979; 86: 87-95.
33. Stern J, Lewis WH. The colorimetric estimation of calcium in serum with ocresolphthalein complexone. Clin Chim Acta 1957; 2: 576-580.
34. Ishii K, Tamaoka A, Takeda T, Ishii K, Iwasaki N, Shoji S. Clinical and neurological features of organoarsenic compound (diphenylarsenic acid) intoxication in Kamisu. Japan Rinsho Shinkeigaku 2006; 46: 768.
35. Lebrecht D, Kirschner J, Geist A, Haberstrah J, Walker UA. Respiratory chain deficiency precedes the disrupted calcium homeostasis in chronic doxorubicin cardio myopathy. Cardiovasc Pathol 2009; 19: 167-174.
36. Jensen RA. Doxorubicin cardiotoxicity: contractile changes after long-term treatment in the rat. J Pharmacol Exper Ther 1986; 236: 197-203.
37. Kalivendi SV, Konorev EA, Cunnigham S, et al. Doxorubicin activates nuclear factor of activated T. lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium. Biochem J 2005; 389: 527-539.
38. Mokni M, Hamlaoui-Guesmi S, Amri M, Marzouki L, Limam F, Aouani E. Grape seed and skin extract protects against acute chemotherapy toxicity induced by doxorubicin in rat heart. Cardiovasc Toxicol 2012; Jan 31: (epub ahead of print) doi 10.1007/s12012-012-9155-1.
39. Bryszewska M, Zavodnik IB, Niekurzak A, Szosland K. Oxidative processes in red blood cells from normal and diabetic individuals. Biochem Mol Biol Int 1995; 37: 345-354.
40. Rizvi SI, Maurya PK. Markers of oxidative stress in erythrocytes during aging in humans. Ann NY Acad Sci 2007; 1100: 373-382.
41. Leonard SS, Xia C, Jiang BH, et al. Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses. Biochem Biophys Res Commun 2003; 309: 1017-1026.
42. Tadolini B, Juliano C, Piu L, Franconi F, Cabrini L. Resveratrol inhibition of lipid peroxidation. Free Radic Res 2000; 33: 105-114.
43. Loguercio C, Tuccillo C, Fererico A, Fogliano V, Del Vecchio Blanco C, Romano M. Alcoholic beverages and gastric epithelial cell viability: effect on oxidative stressinduced damage. J Physiol Pharmacol 2009; 60: 87-92.
44. Spanier G, Xu H, Xia N, et al. Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), gluthathione peroxidise 1 (GPX1) and NADPH oxidase subunit (NOX4). J Physiol Pharmacol 2009; 60: 111-116.
45. Mokni M, Elkahoui S, Limam F, Amri M, Aouani E. Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat. Neurochem Res 2007; 32: 981-987.
46. Sebai H, Sani M, Aouani E, Ghanem-Boughanmi N. Cardioprotective effect of resveratrol on lipopolysaccharide-induced oxidative stress in rat. Drug Chem Toxicol 2011; 34: 146-150.
47. Sebai H, Ben-Attia M, Sani M, Aouani E, Ghanem-Boughanmi N. Protective effect of resveratrol on acute endotoxemia-induced nephrotoxicity in rat through nitric oxide independent mechanism. Free Radic Res 2008; 42: 913-920.
48. Bagchi D, Sen CK, Ray SD, et al. Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract. Mutat Res 2003; 523: 87-97.
49. Sebai H, Sani M, Ghanem-Boughanmi N, Aouani E. Prevention of lipopolysaccharide-induced mouse lethality by resveratrol. Food Chem Toxicol 2010; 48: 1543-1549.
50. Sebai H, Gadacha W, Sani M, Aouani E, Ghanem-Boughanmi N, Ben-Attia M. Protective effect of resveratrol against lipopolysaccharide-induced oxidative stress in rat brain. Brain Inj 2009; 23: 1089-1094.
51. Sebai H, Ben-Attia M, Sani M, Aouani E, GhanemBoughanmi N. Protective effect of resveratrol in endotoxemia-induced acute phase response in rats. Arch Toxicol 2009; 83: 335-340.
52. Eybl V, Kotyzova D, Koutensky J. Comparative study of natural antioxidants-curcumin, resveratrol and melatonin-in cadmium-induced oxidative damage in mice. Toxicology 2006; 225: 150-156.
53. Rivera H, Shibayama M, Tsutsumi V, Perez-Alvarez V, Muriel P. Resveratrol and trimethylated resveratrol protect from acute liver damage induced by CCl4 in the rat. J Appl Toxicol 2008; 28: 147-155.
54. Sehirli O, Ozel Y, Dulundu E, Topaloglu U, Ercan F, Sener G. Grape seed extract treatment reduces hepatic ischemia-reperfusion injury in rats. Phytother Res 2008; 22: 43-48.
55. Upadhyay G, Singh AK, Kumar A, Prakash O, Singh M.P. Resveratrol modulates pyrogallol-induced changes in hepatic toxicity markers, xeno-biotic metabolizing enzymes and oxidative stress. Eur J Pharmacol 2008: 596: 146-152.
56. Hassan-Khabbar S, Cottart CH, Wendum D, et al. Postischemic treatment by trans-resveratrol in rat liver ischemia-reperfusion: a possible strategy in liver surgery. Liver Transplant 2008; 14: 451-459.
57. Das DK, Maulik N. Resveratrol in cardioprotection: a therapeutic promise of alternative medicine. Mol Interv 2006; 6: 36-47.
58. Mikstacka R, Rimando AM, Ignatowicz E. Antioxidant effect of transresveratrol, pterostilbene, quercetin and their combinations in human erythrocytes in vitro. Plant Foods Hum Nutr 2010; 65: 57-63.
59. Barbouti A, Amorgianiotis C, Kolettas E, Kanavaros P, Galaris D. Hydrogen peroxide inhibits caspase-dependent apoptosis by inactivating procaspase-9 in an iron-dependent manner. Free Rad Biol Med 2007; 43: 1377-1387.
60. Isodaa M, Hanawab H, Watanabeb R, et al. Expression of the peptide hormone hepcidin increases in cardiomyocytes under myocarditis and myocardial infarction. J Nutr Biochem 2010; 21: 749-756.
61. Yoshioka T, Homma T, Meyrick B, et al. Oxidants induce transcriptional activation of manganese superoxide dismutase in glomerular cells. Kidney Int 1994; 46: 405-413.
62. Borchi E, Bargelli V, Stillitano F, et al. Enhanced ROS production By NADPH oxidase is correlated to changes in antioxidant enzyme activity in human heart failure. Biochim Biophys Acta 2010; 1802: 331-338.
63. Filip A, Clichici S, Daicoviciu D, et al. Chemopreventive effects of Calluna vulgaris and Vitis vinifera extracts on UVB-induced skin damage in SKH-1 hairless mice. J Physiol Pharmacol 2011; 62: 385-392.
64. Danz E, Skramsted J, Henry N, Bennett JA, Keller RS. Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway. Free Radic Biol Med 2009; 46: 1589-1597.