메뉴 건너뛰기




Volumn 156, Issue 2, 2012, Pages 122-127

Glibenclamide-pregnenolone derivative has greater hypoglycemic effects and biodistribution than glibenclamide-OH in alloxan-rats

Author keywords

Biodistribution; Glibenclamide; Glucose; Pregnenolone

Indexed keywords

ALLOXAN; ANTIDIABETIC AGENT; DRUG DERIVATIVE; GLIBENCLAMIDE; METFORMIN; PREGNENOLONE;

EID: 84863994772     PISSN: 12138118     EISSN: 18047521     Source Type: Journal    
DOI: 10.5507/bp.2012.028     Document Type: Article
Times cited : (11)

References (25)
  • 1
    • 84965086616 scopus 로고
    • The action of hypoglycaemic sulphonylureas on carbohydrate metabolism in the fasted rat
    • Kelsey I, Wright P. The action of hypoglycaemic sulphonylureas on carbohydrate metabolism in the fasted rat. Br J Pharmacol Chemother 1957;12(3):350-5.
    • (1957) Br J Pharmacol Chemother , vol.12 , Issue.3 , pp. 350-355
    • Kelsey, I.1    Wright, P.2
  • 2
    • 0018777905 scopus 로고
    • Effect of two sulphonylureas on the dose kinetics of glucose-induced insulin release in normal and diabetic subjects
    • Cerasi E, Efendic S, Thornqvist C, Luft R. Effect of two sulphonylureas on the dose kinetics of glucose-induced insulin release in normal and diabetic subjects. Acta Endocrinol (Copenh) 1979;91(2):282-93.
    • (1979) Acta Endocrinol (Copenh) , vol.91 , Issue.2 , pp. 282-293
    • Cerasi, E.1    Efendic, S.2    Thornqvist, C.3    Luft, R.4
  • 3
    • 0033377296 scopus 로고    scopus 로고
    • The use of sulphonylureas in the elderly
    • Graal MB, Wolffenbuttel BH. The use of sulphonylureas in the elderly. Drugs Aging 1999;15(6):471-81.
    • (1999) Drugs Aging , vol.15 , Issue.6 , pp. 471-481
    • Graal, M.B.1    Wolffenbuttel, B.H.2
  • 4
    • 0018758258 scopus 로고
    • Increased insulin sensitivity and cellular insulin binding in obese diabetics following treatment with glibenclamide
    • Beck-Nielsen H, Pedersen O, Lindskov HO. Increased insulin sensitivity and cellular insulin binding in obese diabetics following treatment with glibenclamide. Acta Endocrinol (Copenh) 1979;90(3):451-62.
    • (1979) Acta Endocrinol (Copenh) , vol.90 , Issue.3 , pp. 451-462
    • Beck-Nielsen, H.1    Pedersen, O.2    Lindskov, H.O.3
  • 5
    • 0027193068 scopus 로고
    • Metabolic and hemodynamic effects of metformin and glibenclamide in normotensive NIDDM patients
    • Chan J, Tomlinson B, Critchley J, Cockram C, Walden R. Metabolic and hemodynamic effects of metformin and glibenclamide in normotensive NIDDM patients. Diabetes Care 1993;16(7):1035-38.
    • (1993) Diabetes Care , vol.16 , Issue.7 , pp. 1035-1038
    • Chan, J.1    Tomlinson, B.2    Critchley, J.3    Cockram, C.4    Walden, R.5
  • 6
    • 0028357199 scopus 로고
    • Efficacy of 24-week monotherapy with ascarbose, glibenclamide, or placebo in NIDDM patients
    • Hoffmann J, Spengler M. Efficacy of 24-week monotherapy with ascarbose, glibenclamide, or placebo in NIDDM patients. The Essen Study. Diabetes Care 1994;17(6):561-6.
    • (1994) The Essen Study. Diabetes Care , vol.17 , Issue.6 , pp. 561-566
    • Hoffmann, J.1    Spengler, M.2
  • 7
    • 0020578096 scopus 로고
    • Glibenclamide-associated hypoglycaemia: A report on 57 cases
    • Asplund K, Wiholm B, Lithner F. Glibenclamide-associated hypoglycaemia: a report on 57 cases. Diabetologia 1983;24:412-17.
    • (1983) Diabetologia , vol.24 , pp. 412-417
    • Asplund, K.1    Wiholm, B.2    Lithner, F.3
  • 8
    • 0023935536 scopus 로고
    • Sulphonylureas and hypoglycaemia
    • Ferner RE, Neil HA. Sulphonylureas and hypoglycaemia. Br Med J 1988;296:959-60.
    • (1988) Br Med J , vol.296 , pp. 959-960
    • Ferner, R.E.1    Neil, H.A.2
  • 10
    • 0023350882 scopus 로고
    • The relationship between the pharmacokinetics and pharmacodynamics effects of oral hypoglycaemic drugs
    • Ferner RE, Chaplin S. The relationship between the pharmacokinetics and pharmacodynamics effects of oral hypoglycaemic drugs. ClinPharmacokin 1987;12:379-401.
    • (1987) ClinPharmacokin , vol.12 , pp. 379-401
    • Ferner, R.E.1    Chaplin, S.2
  • 11
    • 0022414013 scopus 로고
    • Mechanism of the stimulation of insulin release in vitro by HB 699, a benzoic acid derivative similar to the non-sulphonylurea moiety of glibenclamide
    • Garrino M, Schmeer W, Nenquin M, Meissner H, Henquin J. Mechanism of the stimulation of insulin release in vitro by HB 699, a benzoic acid derivative similar to the non-sulphonylurea moiety of glibenclamide. Diabetologia 1985;28:697-703.
    • (1985) Diabetologia , vol.28 , pp. 697-703
    • Garrino, M.1    Schmeer, W.2    Nenquin, M.3    Meissner, H.4    Henquin, J.5
  • 12
    • 0038729523 scopus 로고    scopus 로고
    • Characteristics and time course of severe glimepiride-versus glibenclamide-induced hypoglycaemia
    • Holstein A, Plaschke A, Hammer C, Egberts E. Characteristics and time course of severe glimepiride-versus glibenclamide-induced hypoglycaemia. Eur J Clin Pharmacol 2003;59:91-7
    • (2003) Eur J Clin Pharmacol , vol.59 , pp. 91-97
    • Holstein, A.1    Plaschke, A.2    Hammer, C.3    Egberts, E.4
  • 13
    • 0035667081 scopus 로고    scopus 로고
    • Lower incidence of severe hypoglycaemic in patients with type 2 diabetes treated with glimepiride versus glibenclamide
    • Holstein A, Plaschke A, Egberts E. Lower incidence of severe hypoglycaemic in patients with type 2 diabetes treated with glimepiride versus glibenclamide. Diabetes/Metabolism Res Rev 2001;17(6):467-73.
    • (2001) Diabetes/Metabolism Res Rev , vol.17 , Issue.6 , pp. 467-473
    • Holstein, A.1    Plaschke, A.2    Egberts, E.3
  • 14
    • 0016435231 scopus 로고
    • Comparison of the Pharmacokinetics of Glipizide and Glibenclamide in Man
    • Balant L, Fabre J, Zahnd G. Comparison of the Pharmacokinetics of Glipizide and Glibenclamide in Man. Eur J Clin Pharmacol 1975;8:63-9.
    • (1975) Eur J Clin Pharmacol , vol.8 , pp. 63-69
    • Balant, L.1    Fabre, J.2    Zahnd, G.3
  • 17
    • 80053378664 scopus 로고    scopus 로고
    • García-Cervera. Synthesis of Glibenclamide-pregnenolone conjugate and its relationship with physicochemical descriptors log P, π, Rm, Vm, Pc and St
    • Figueroa-Valverde L, Díaz-Cedillo F, García-Cervera. Synthesis of Glibenclamide-pregnenolone conjugate and its relationship with physicochemical descriptors log P, π, Rm, Vm, Pc and St. Asian J Chem 2011;23(9):3999-4002.
    • (2011) Asian J Chem , vol.23 , Issue.9 , pp. 3999-4002
    • Figueroa-Valverde, L.1    Díaz-Cedillo, F.2
  • 18
    • 78249268018 scopus 로고    scopus 로고
    • Design and Synthesis of Carbamazepine-Alkyne Conjugate as Antidiabetic Agent: Study of Chemical Descriptors (log P and π)
    • Figueroa-Valverde L, Díaz-Cedillo F, Camacho-Luis A, López-Ramos M, García-Cervera E. Design and Synthesis of Carbamazepine-Alkyne Conjugate as Antidiabetic Agent: Study of Chemical Descriptors (log P and π). Asian J Chem 2010;22(9):7057-64.
    • (2010) Asian J Chem , vol.22 , Issue.9 , pp. 7057-7064
    • Figueroa-Valverde, L.1    Díaz-Cedillo, F.2    Camacho-Luis, A.3    López-Ramos, M.4    García-Cervera, E.5
  • 19
    • 0018761415 scopus 로고
    • Radioimmunoassay of glibenclamide
    • Kawashima K, Kuzuya T, Matsuda A. Radioimmunoassay of glibenclamide. Diabetes 1979;28(3):221-6.
    • (1979) Diabetes , vol.28 , Issue.3 , pp. 221-226
    • Kawashima, K.1    Kuzuya, T.2    Matsuda, A.3
  • 20
    • 33846807816 scopus 로고    scopus 로고
    • Synthesis and evaluation of a glibenclamide glucose-conjugate: A potential new lead compound for substituted glibenclamide derivatives as islet imaging agents
    • Schneider S, Ueberberg S, Korobeynikov A, Schechinger W, Schwanstecher C, Schwanstecher M, Klein H, Schirrmacher E. Synthesis and evaluation of a glibenclamide glucose-conjugate: A potential new lead compound for substituted glibenclamide derivatives as islet imaging agents. Regulatory Peptides 2007;139(1-3):122-7.
    • (2007) Regulatory Peptides , vol.139 , Issue.1-3 , pp. 122-127
    • Schneider, S.1    Ueberberg, S.2    Korobeynikov, A.3    Schechinger, W.4    Schwanstecher, C.5    Schwanstecher, M.6    Klein, H.7    Schirrmacher, E.8
  • 21
    • 0032893826 scopus 로고    scopus 로고
    • Technetium-99m Complexes with Steroid-2-aminooxyethyliminodiaceticAcid Conjugates
    • Yoda R, Arube Y, Takata J, Nagata Y, Matsushima Y. Technetium-99m Complexes with Steroid-2-aminooxyethyliminodiaceticAcid Conjugates. Chem Pharm Bull 1999;47(3):413-6.
    • (1999) Chem Pharm Bull , vol.47 , Issue.3 , pp. 413-416
    • Yoda, R.1    Arube, Y.2    Takata, J.3    Nagata, Y.4    Matsushima, Y.5
  • 22
    • 84872601046 scopus 로고    scopus 로고
    • Formulación de 99M TC-Macroagregadosde albúmina para estudios de perfusión pulmonar
    • Yumisley A, Rivero A, Zayas F, Mesa N, Hernández I, León M. Formulación de 99M TC-Macroagregadosde albúmina para estudios de perfusión pulmonar. Nucleus 2009;45:19-25.
    • (2009) Nucleus , vol.45 , pp. 19-25
    • Yumisley, A.1    Rivero, A.2    Zayas, F.3    Mesa, N.4    Hernández, I.5    León, M.6
  • 23
    • 0035691617 scopus 로고    scopus 로고
    • The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas
    • Szkudelski T. The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res 2001:50:536-46.
    • (2001) Physiol Res , vol.50 , pp. 536-546
    • Szkudelski, T.1
  • 24
    • 58149186568 scopus 로고    scopus 로고
    • Mechanism of interaction of hypoglycemic agents glimepiride and glipizide with human serum albumin
    • Seedher N, Kanojia M. Mechanism of interaction of hypoglycemic agents glimepiride and glipizide with human serum albumin. Central Eur J Chem 2009;7(1):96-104.
    • (2009) Central Eur J Chem , vol.7 , Issue.1 , pp. 96-104
    • Seedher, N.1    Kanojia, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.