Design and synthesis of carbamazepine-alkyne conjugate as antidiabetic agent: Study of chemical descriptors (log P andπ)

Asian Journal of Chemistry

Volumn 22, Issue 9, 2010, Pages 7057-7064

  Figueroa Valverde, Lauro ^a   Díaz Cedillo, Francisco ^a,b   Camacho Luis, Abelardo ^a,c   LóPez Ramos, Maria ^a   Garcia Cervera, Elodia ^a  

^a UNIVERSIDAD AUTÓNOMA DE CAMPECHE   (Mexico)

^b INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

^c Universidad Autónoma Del Estado de Durango   (Mexico)

Author keywords

1 Hexyne; Antidiabetic activity; Benzaldehyde; Carbamazepine alkyne

Indexed keywords

EID: 78249268018     PISSN: 09707077     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. E. Gordon, R. Barret, W. Dower, S. Fodor and M. Gallop, J. Med. Chem., 37, 1385 (1994).
2. N. Terret, M. Gardner, D. Gordon, R. Kobylecki and J. Steele, Tetrahedron, 51, 8135 (1995).
3. F. Balkenhohol, C. Bussche, A. Lansky, C. Zechel, Angew. Chem. Int. Ed. Engl., 35, 2289 (1996).
4. C. Zhe-Feng, L. Quan, L. Ping, G. Zong and S. Zhu, Acta Pharm. Sin., 27, 597 (2006).
5. K. Masuda, Y. Okamoto, Y. Tsuura, S. Kato, T. Miura and K. Tsuda, Diabetologia, 38, 24 (1995).
6. P. Zhonghua, L. Xiaofeng, L. Kenton, W. Thomas, V. Geldern and P. Wiedeman, J. Med. Chem., 49, 3530 (2006).
7. E. Christianser, C. Urban, N. Merten, K. Liebscher, K. Karper and A. Hamacher, J. Med. Chem., 51, 7061 (2008).
8. J. Madar, H. Kopecka, D. Pireh, H. Yong, Z. Pei and X. Li, J. Med. Chem., 49, 6416 (2006).
9. H. Hitoshi, A. Osamu, H. Yorihisa, Y. Seiji, M. Masayuki and K. Yasuhiro, J. Med. Chem., 44, 170 (2001).
10. R. Mannhold and H. Waterbeemd, J. Comput-Aided Mol. Design, 15, 337 (2001).
11. A. Shamaony, S. Al-Khazraji and H. Twaiji, J. Ethnopharmacol., 43, 167 (1994).
12. S. Tu, F. Fang, C. Miao, H. Jiang, Y. Feng and D. Shi, Tetrahedron Lett., 44, 6153 (2003).
13. P. Salehi and N. Fard, Tetrahedron Lett., 44, 2889 (2003).
14. R. Yarapathi, S. Kurva and S. Tammishetti, Catal. Commun., 5, 511 (2004).
15. J. Bussolari and P. McDonnell, J. Org. Chem., 65, 6777 (2005).
16. F. Shirini, K. Marjani and H. Nahzomi, Arkivoc, 51 (2007).
17. R. Crossland and K. Servis, J. Org. Chem., 35, 3195 (1970).
18. N. Gommermann, C. Koradin, K. Polborn and P. Knochel, Angew. Chem., 115, 5401 (2003).
19. M. Anary and H. Anaraki, Monatsh. Chem., 140, 3497 (2009).
20. T. Szkudelski, Physiol. Res., 50, 536 (2001).
21. A. Leo, P. Jow and C. Silipo, J. Med. Chem., 18, 865 (1975).
22. A. Leo and D. Hoekman, Persp. Drug. Discov. Design, 18, 19 (2000).
23. C. Hansch, A. Leo and R. Taft, Chem. Rev., 91, 165 (1991).
24. C. Hansch, Acct. Chem. Res., 2, 232 (1969).
25. N. Verma, M. Mittal and R. Verma, Calicut Med. J., 6, 1 (2008).