Selective Rac1 inhibition protects renal tubular epithelial cells from oxalate-induced NADPH oxidase-mediated oxidative cell injury

Urological Research

Volumn 40, Issue 4, 2012, Pages 415-423

  Thamilselvan, Vijayalakshmi ^a   Menon, Mani ^a   Thamilselvan, Sivagnanam ^a  

^a HENRY FORD HEALTH SYSTEM   (United States)

Author keywords

Calcium oxalate; Free radical; Kidney stone; NADPH oxidase; Oxalate; Rac1

Indexed keywords

GUANOSINE TRIPHOSPHATASE; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; OXALIC ACID; PROTEIN INHIBITOR; PROTEIN KINASE C ALPHA; RAC1 INHIBITOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG;

CELL DAMAGE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME RELEASE; HUMAN; HUMAN CELL; KIDNEY TUBULE EPITHELIUM; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

AMINOQUINOLINES; ANIMALS; CYTOPROTECTION; EPITHELIAL CELLS; KIDNEY TUBULES; LLC-PK1 CELLS; NADPH OXIDASE; OXALATES; OXIDATIVE STRESS; PROTEIN KINASE C; PROTEIN TRANSPORT; PYRIMIDINES; RAC1 GTP-BINDING PROTEIN; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SWINE;

EID: 84863986002     PISSN: 03005623     EISSN: 14340879     Source Type: Journal    
DOI: 10.1007/s00240-011-0405-7     Document Type: Conference Paper

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