Alpha-1 adrenergic receptors are localized on presynaptic elements in the nucleus accumbens and regulate mesolimbic dopamine transmission

Neuropsychopharmacology

Volumn 37, Issue 9, 2012, Pages 2161-2172

  Mitrano, Darlene A ^a   Schroeder, Jason P ^a   Smith, Yoland ^a,b   Cortright, James J ^c   Bubula, Nancy ^c   Vezina, Paul ^c   Weinshenker, David ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

alpha 1 adrenergic; cocaine; dopamine; norepinephrine; nucleus accumbens; ventral tegmental area

Indexed keywords

4 AMINOBUTYRIC ACID; ALPHA 1 ADRENERGIC RECEPTOR; COCAINE; DOPAMINE; GLUTAMIC ACID; NEUROTRANSMITTER; TERAZOSIN;

ANIMAL EXPERIMENT; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; ELECTRON MICROSCOPY; GLUTAMINERGIC TERMINAL; IMMUNOCYTOCHEMISTRY; IMMUNOGOLD LABELING; LOCOMOTION; MALE; MESOLIMBIC DOPAMINERGIC SYSTEM; NERVE ENDING; NERVE FIBER; NONHUMAN; NUCLEUS ACCUMBENS; PHENOTYPE; PREFRONTAL CORTEX; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SYNAPTIC MEMBRANE; VENTRAL TEGMENTUM;

ANIMALS; COCAINE; DOPAMINE; INFUSIONS, INTRAVENTRICULAR; LIMBIC SYSTEM; MALE; MORPHINE; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; PRESYNAPTIC TERMINALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-1; SYNAPTIC TRANSMISSION;

EID: 84863982701     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.68     Document Type: Article

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