Processing of CXCL12 by different osteoblast-secreted cathepsins

Stem Cells and Development

Volumn 21, Issue 11, 2012, Pages 1924-1935

  Staudt, Nicole D ^a,c   Maurer, Andreas ^b   Spring, Bärbel ^a   Kalbacher, Hubert ^b   Aicher, Wilhelm K ^b   Klein, Gerd ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN; CATHEPSIN B; CATHEPSIN K; CATHEPSIN L; CATHEPSIN X; CHEMOKINE RECEPTOR CXCR4; DITHIOTHREITOL;

ARTICLE; CELL ADHESION; CELL INTERACTION; CELL ISOLATION; CELL MIGRATION; CELL TYPE; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; OBSERVATION; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN PROCESSING;

ANTIGENS, CD34; CATHEPSIN B; CATHEPSIN K; CATHEPSINS; CELL ADHESION; CELL MOVEMENT; CELLULAR MICROENVIRONMENT; CHEMOKINE CXCL12; CULTURE MEDIA, CONDITIONED; DITHIOTHREITOL; ENZYME ACTIVATION; ENZYME ASSAYS; HEMATOPOIETIC STEM CELLS; HUMANS; OSTEOBLASTS; PRIMARY CELL CULTURE; PROTEIN PRECURSORS; PROTEOLYSIS; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TIME FACTORS;

EID: 84863953614     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2011.0307     Document Type: Article

References (34)

1. Brix K, A Dunkhorst, K Mayer and S Jordans. (2008). Cysteine cathepsins: cellular roadmap to different functions. Biochimie 90:194-207. (Pubitemid 351172569)
2. Mohamed MM and BF Sloane. (2006). Cysteine cathepsins: multifunctional enzymes in cancer.Nat Rev Cancer 6:764-775. (Pubitemid 44450465)
3. Turk V, B Turk and D Turk. (2001). Lysosomal cysteine proteases: facts and opportunities. EMBO J 20:4629-4633. (Pubitemid 32848615)
4. Reiser J, B Adair and T Reinheckel. (2010). Specialized roles for cysteine cathepsins in health and disease. J Clin Invest 120:3421-3431.
5. Delaisse JM, TL Andersen, MT Engsig, K Henriksen, T Troen and L Blavier. (2003). Matrix metalloproteinases (MMP) and cathepsin K contribute differently to osteoclastic activities. Microsc Res Tech 61:504-513. (Pubitemid 36890583)
6. Staudt ND, WK Aicher, H Kalbacher, S Stevanovic, AK Carmona, M Bogyo and G Klein. (2010). Cathepsin X is secreted by human osteoblasts, digests CXCL-12 and impairs adhesion of hematopoietic stem and progenitor cells to osteoblasts. Haematologica 95:1452-1460.
7. Aisa MC, T Beccari, E Costanzi and D Maggio. (2003). Cathepsin B in osteoblasts. Biochim Biophys Acta 1621:149-159. (Pubitemid 36515096)
8. Mandelin J, M Hukkanen, TF Li, M Korhonen, M Liljestrom, T Sillat, R Hanemaaijer, J Salo, S Santavirta and YT Konttinen. (2006). Human osteoblasts produce cathepsin K. Bone 38:769-777. (Pubitemid 44498577)
9. Lymperi S, F Ferraro and DT Scadden. (2010). The HSC niche concept has turned 31. Has our knowledge matured? Ann N Y Acad Sci 1192:12-18.
10. Kiel MJ and SJ Morrison. (2008). Uncertainty in the niches that maintain haematopoietic stem cells. Nat Rev Immunol 8:290-301. (Pubitemid 351432804)
11. Wilson A and A Trumpp. (2006). Bone-marrow haematopoietic-stem-cell niches. Nat Rev Immunol 6:93-106. (Pubitemid 43361585)
12. Yin T and L Li. (2006). The stem cell niches in bone. J Clin Invest 116:1195-1201.
13. Bhattacharya D, A Czechowicz, AG Ooi, DJ Rossi, D Bryder and IL Weissman. (2009). Niche recycling through divisionindependent egress of hematopoietic stem cells. J Exp Med 206:2837-2850.
14. Dar A, O Kollet and T Lapidot. (2006). Mutual, reciprocal SDF-1/CXCR4 interactions between hematopoietic and bone marrow stromal cells regulate human stem cell migration and development in NOD/SCID chimeric mice. Exp Hematol 34:967-975. (Pubitemid 44080383)
15. Neiva K, YX Sun and RS Taichman. (2005). The role of osteoblasts in regulating hematopoietic stem cell activity and tumor metastasis. Braz J Med Biol Res 38:1449-1454. (Pubitemid 41440216)
16. Sugiyama T, H Kohara, M Noda and T Nagasawa. (2006). Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity 25:977-988. (Pubitemid 44894948)
17. Marquez-Curtis L, A Jalili, K Deiteren, N Shirvaikar, AM Lambeir and A Janowska-Wieczorek. (2008). Carboxypeptidase M expressed by human bone marrow cells cleaves the C-terminal lysine of stromal cell-derived factor-1alpha: another player in hematopoietic stem/progenitor cell mobilization? Stem Cells 26:1211-1220
18. Vagima Y, A Avigdor, P Goichberg, S Shivtiel, M Tesio, A Kalinkovich, K Golan, A Dar, O Kollet, et al. (2009). MT1-MMP and RECK are involved in human CD34 + progenitor cell retention, egress, and mobilization. J Clin Invest 119:492-503.
19. Heissig B, K Hattori, S Dias, M Friedrich, B Ferris, NR Hackett, RG Crystal, P Besmer, D Lyden, MA Moore, Z Werb, et al. (2002). Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell 109:625-637. (Pubitemid 34628725)
20. Jin F, Q Zhai, L Qiu, H Meng, D Zou, Y Wang, Q Li, Z Yu, J Han and B Zhou. (2008). Degradation of BM SDF-1 by MMP-9: the role in G-CSF-induced hematopoietic stem/progenitor cell mobilization. Bone Marrow Transplant 42:581-588.
21. Raaijmakers MH. (2010). Regulating traffic in the hematopoietic stem cell niche. Haematologica 95:1439-1441.
22. Hergeth SP, WK Aicher, M Essl, TD Schreiber, T Sasaki and G Klein. (2008). Characterization and functional analysis of osteoblast-derived fibulins in the human hematopoietic stem cell niche. Exp Hematol 36:1022-1034.
23. Rifas L, JS Kenney, M Marcelli, R Pacifici, SL Cheng, LL Dawson and LV Avioli. (1995). Production of interleukin-6 in human osteoblasts and human bone marrow stromal cells: evidence that induction by interleukin-1 and tumor necrosis factor-alpha is not regulated by ovarian steroids. Endocrinology 136:4056-4067.
24. Thalmeier K, P Meissner, G Reisbach, M Falk, A Brechtel and P Dormer. (1994). Establishment of two permanent human bone marrow stromal cell lines with long-term post irradiation feeder capacity. Blood 83:1799-1807. (Pubitemid 24107902)
25. Roecklein BA and B Torok-Storb. (1995). Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papilloma virus E6/E7 genes. Blood 85:997-1005.
26. Lapidot T and I Petit. (2002). Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. Exp Hematol 30:973-981. (Pubitemid 35286613)
27. Lekli I, N Gurusamy, D Ray, A Tosaki and DK Das. (2009). Redox regulation of stem cell mobilization. Can J Physiol Pharmacol 87:989-995.
28. Grek CL, DM Townsend and KD Tew. (2011). The impact of redox and thiol status on the bone marrow: pharmacological intervention strategies. Pharmacol Ther 129:172-184.
29. Hattori K, B Heissig, K Tashiro, T Honjo, M Tateno, JH Shieh, NR Hackett, MS Quitoriano, RG Crystal, S Rafii and MA Moore. (2001). Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. Blood 97:3354-3360.
30. Cho SY, M Xu, J Roboz, M Lu, J Mascarenhas and R Hoffman. (2010). The effect of CXCL12 processing on CD34 + cell migration in myeloproliferative neoplasms. Cancer Res 70:3402-3410.
31. Crump MP, JH Gong, P Loetscher, K Rajarathnam, A Amara, F Arenzana-Seisdedos, JL Virelizier, M Baggiolini, BD Sykes and I Clark-Lewis. (1997). Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J 16:6996-7007. (Pubitemid 27520800)
32. Sivaraman J, DK Nagler, R Zhang, R Menard and M Cygler. (2000). Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine. J Mol Biol 295:939-951.
33. Lechner AM, I Assfalg-Machleidt, S Zahler, M Stoeckelhuber, W Machleidt, M Jochum and DK Nagler. (2006). RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties. J Biol Chem 281:39588-39597. (Pubitemid 46041918)
34. Turk V, V Stoka and D Turk. (2008). Cystatins: biochemical and structural properties, and medical relevance. Front Biosci 13:5406-5420.