메뉴 건너뛰기




Volumn 27, Issue 1, 2012, Pages 27-33

Combined mutational analysis of KRAS, NRAS and BRAF genes in Indian patients with colorectal carcinoma

Author keywords

BRAF; Colorectal carcinoma; EGFR; KRAS; NRAS

Indexed keywords

B RAF KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; K RAS PROTEIN; RAS PROTEIN;

EID: 84863940087     PISSN: 03936155     EISSN: None     Source Type: Journal    
DOI: 10.5301/JBM.2012.9108     Document Type: Article
Times cited : (20)

References (36)
  • 2
    • 42649145667 scopus 로고    scopus 로고
    • Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
    • Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008; 26: 1626-1634.
    • (2008) J Clin Oncol , vol.26 , pp. 1626-1634
    • Amado, R.G.1    Wolf, M.2    Peeters, M.3
  • 4
    • 70349939382 scopus 로고    scopus 로고
    • Biomarkers predicting clinical outcome of epidermal growth factor receptor targeted therapy in metastatic colorectal cancer
    • Siena S, Sartore-Bianchi A, Di Nicolantonio F, Balfour J, Bardelli A. Biomarkers predicting clinical outcome of epidermal growth factor receptor targeted therapy in metastatic colorectal cancer. J Natl Cancer Inst 2009; 101: 1308-1324.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1308-1324
    • Siena, S.1    Sartore-Bianchi, A.2    Di Nicolantonio, F.3    Balfour, J.4    Bardelli, A.5
  • 5
    • 54949085398 scopus 로고    scopus 로고
    • K-ras mutations and benefit from cetuximab in advanced colorectal cancer
    • Karapetis CS, Khambata-Ford S, Jonker DJ, et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 2008; 359: 1757-1765.
    • (2008) N Engl J Med , vol.359 , pp. 1757-1765
    • Karapetis, C.S.1    Khambata-Ford, S.2    Jonker, D.J.3
  • 6
    • 62449302407 scopus 로고    scopus 로고
    • PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-target-ed monoclonal antibodies
    • Sartore-Bianchi F, Martini M, Molinari F, et al. PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-target-ed monoclonal antibodies. Cancer Res 2009; 69: 1851-1857.
    • (2009) Cancer Res , vol.69 , pp. 1851-1857
    • Sartore-Bianchi, F.1    Martini, M.2    Molinari, F.3
  • 7
    • 57449095367 scopus 로고    scopus 로고
    • Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
    • Di Nicolantonio F, Martini M, Molinari F, et al. Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. J Clin Oncol 2008; 26: 5705-5712.
    • (2008) J Clin Oncol , vol.26 , pp. 5705-5712
    • Di Nicolantonio, F.1    Martini, M.2    Molinari, F.3
  • 8
    • 70350028742 scopus 로고    scopus 로고
    • Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer
    • Sartore-Bianchi A, Di Nicolantonio F, Nichelatti M, et al. Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer. PLoS One 2009; 4: e7287.
    • (2009) PLoS One , vol.4
    • Sartore-Bianchi, A.1    Di Nicolantonio, F.2    Nichelatti, M.3
  • 9
    • 42149083899 scopus 로고    scopus 로고
    • Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers
    • Barault L, Veyrie N, Jooste V, et al. Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers. Int J Cancer 2008; 122: 2255-2259.
    • (2008) Int J Cancer , vol.122 , pp. 2255-2259
    • Barault, L.1    Veyrie, N.2    Jooste, V.3
  • 10
    • 65649086786 scopus 로고    scopus 로고
    • PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal
    • Prenen H, De Schutter J, Jacobs B, et al. PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal Clin Cancer Res 2009; 15: 3184-3188.
    • (2009) Clin Cancer Res , vol.15 , pp. 3184-3188
    • Prenen, H.1    de Schutter, J.2    Jacobs, B.3
  • 11
    • 72449185665 scopus 로고    scopus 로고
    • The role of KRAS, BRAF, NRAS and PIK3CA mutations as markers of resistance to cetuximab in chemorefractory metastatic colorectal cancer
    • abstr 4020
    • Lambrechts D, Roock WD, Prenen H, et al. The role of KRAS, BRAF, NRAS and PIK3CA mutations as markers of resistance to cetuximab in chemorefractory metastatic colorectal cancer. J Clin Oncol 2009; 27:15s (abstr 4020).
    • (2009) J Clin Oncol , vol.27
    • Lambrechts, D.1    Roock, W.D.2    Prenen, H.3
  • 12
    • 61449258442 scopus 로고    scopus 로고
    • K-ras mutations and cetuximab in colorectal cancer
    • De Roock W, Lambrechts D, Tejpar S. K-ras mutations and cetuximab in colorectal cancer. N Engl J Med 2009; 360: 834-836.
    • (2009) N Engl J Med , vol.360 , pp. 834-836
    • de Roock, W.1    Lambrechts, D.2    Tejpar, S.3
  • 13
    • 53149097362 scopus 로고    scopus 로고
    • BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: Primary or secondary genetic events in colorectal carcinogenesis
    • Velho S, Moutinho C, Cirnes L, et al. BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis. BMC Cancer 2008; 8: 255.
    • (2008) BMC Cancer , vol.8 , pp. 255
    • Velho, S.1    Moutinho, C.2    Cirnes, L.3
  • 14
    • 21644473447 scopus 로고    scopus 로고
    • Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression
    • Calistri D, Rengucci C, Seymour I, et al. Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression. J Cell Physiol 2005; 204: 484-488.
    • (2005) J Cell Physiol , vol.204 , pp. 484-488
    • Calistri, D.1    Rengucci, C.2    Seymour, I.3
  • 15
    • 14844361741 scopus 로고    scopus 로고
    • Frequency and spectrum of K-RAS codons 12 and 13 mutations in colorectal adenocarcinomas from Taiwan
    • Wu CM, Tang R, Wang JY, et al. Frequency and spectrum of K-RAS codons 12 and 13 mutations in colorectal adenocarcinomas from Taiwan. Cancer Genet Cytogenet 2005; 158: 55-60.
    • (2005) Cancer Genet Cytogenet , vol.158 , pp. 55-60
    • Wu, C.M.1    Tang, R.2    Wang, J.Y.3
  • 18
    • 47749128875 scopus 로고    scopus 로고
    • KRAS mutation profile in colorectal carcinoma and novel mutation-internal tandem duplication in KRAS
    • Wójcik P, Kulig J, Okoń K, et al. KRAS mutation profile in colorectal carcinoma and novel mutation-internal tandem duplication in KRAS. Pol J Pathol 2008; 59: 93-96.
    • (2008) Pol J Pathol , vol.59 , pp. 93-96
    • Wójcik, P.1    Kulig, J.2    Okoń, K.3
  • 19
    • 1542503817 scopus 로고    scopus 로고
    • Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelo-dysplastic syndrome to acute myeloid leukemia
    • Shih LY, Huang CF, Wang PN, et al. Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelo-dysplastic syndrome to acute myeloid leukemia. Leukemia 2004; 18: 466-475.
    • (2004) Leukemia , vol.18 , pp. 466-475
    • Shih, L.Y.1    Huang, C.F.2    Wang, P.N.3
  • 20
    • 33644586429 scopus 로고    scopus 로고
    • Detection of BRAF mutation in thyroid papillary carcinomas by mutant allele-specific PCR amplification (MASA)
    • Sapio MR, Posca D, Troncone G, et al. Detection of BRAF mutation in thyroid papillary carcinomas by mutant allele-specific PCR amplification (MASA). Eur J Endocrinol 2006; 154: 341-348.
    • (2006) Eur J Endocrinol , vol.154 , pp. 341-348
    • Sapio, M.R.1    Posca, D.2    Troncone, G.3
  • 21
    • 0033959761 scopus 로고    scopus 로고
    • p53 and KRAS gene mutations in carcinoma of the rectum among Finnish women
    • Servomaa K, Kiuru A, Kosma VM, Hirvikoski P, Rytömaa T. p53 and KRAS gene mutations in carcinoma of the rectum among Finnish women. Mol Pathol 2000; 53: 24-30.
    • (2000) Mol Pathol , vol.53 , pp. 24-30
    • Servomaa, K.1    Kiuru, A.2    Kosma, V.M.3    Hirvikoski, P.4    Rytömaa, T.5
  • 23
    • 23944488225 scopus 로고    scopus 로고
    • The prognostic significance of K- ras, p53 and APC mutations in colorectal carcinoma
    • Conlin A, Smith G, Carey FA, Wolf CR, Steele RJ. The prognostic significance of K- ras, p53 and APC mutations in colorectal carcinoma. Gut 2005; 54: 1283-1286.
    • (2005) Gut , vol.54 , pp. 1283-1286
    • Conlin, A.1    Smith, G.2    Carey, F.A.3    Wolf, C.R.4    Steele, R.J.5
  • 24
    • 77952536391 scopus 로고    scopus 로고
    • Two multiplex assays that simultaneously identify 22 possible mutation sites in the RAS, BRAF, NRAS and PIK3CA genes
    • Lurkin I, Stoehr R, Hurst CD, et al. Two multiplex assays that simultaneously identify 22 possible mutation sites in the RAS, BRAF, NRAS and PIK3CA genes. PLoS One 2010; 5: e8802.
    • (2010) PLoS One , vol.5
    • Lurkin, I.1    Stoehr, R.2    Hurst, C.D.3
  • 25
    • 75749102647 scopus 로고    scopus 로고
    • Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: Results of the transla-tional study on the PETACC-3, EORTC 40993, SAKK 60-00 trial
    • Roth AD, Tejpar S, Delorenzi M, et al. Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the transla-tional study on the PETACC-3, EORTC 40993, SAKK 60-00 trial. J Clin Oncol 2010; 28: 466-474.
    • (2010) J Clin Oncol , vol.28 , pp. 466-474
    • Roth, A.D.1    Tejpar, S.2    Delorenzi, M.3
  • 26
    • 78649473910 scopus 로고    scopus 로고
    • The BRAF V600E mutation is an independent prognostic factor for survival in stage II and stage III colon cancer patients
    • Fariña-Sarasqueta A, van Lijnschoten G, Moerland E, et al. The BRAF V600E mutation is an independent prognostic factor for survival in stage II and stage III colon cancer patients. Ann Oncol 2010; 21: 2396-2402.
    • (2010) Ann Oncol , vol.21 , pp. 2396-2402
    • Fariña-Sarasqueta, A.1    van Lijnschoten, G.2    Moerland, E.3
  • 27
    • 0141593677 scopus 로고    scopus 로고
    • BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair
    • Liang W, Julie MC, Jennifer LW et al. BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair. Cancer Res 2003; 63; 5209-5212.
    • (2003) Cancer Res , vol.63 , pp. 5209-5212
    • Liang, W.1    Julie, M.C.2    Jennifer, L.W.3
  • 29
    • 17144372612 scopus 로고    scopus 로고
    • Detection of BRAF mutations in colorectal tumours and peritoneal washings using a mismatch ligation assay
    • Busby K, Morris A. Detection of BRAF mutations in colorectal tumours and peritoneal washings using a mismatch ligation assay. Clin Pathol 2005; 58: 372-375.
    • (2005) Clin Pathol , vol.58 , pp. 372-375
    • Busby, K.1    Morris, A.2
  • 30
    • 0037112438 scopus 로고    scopus 로고
    • Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia
    • Siu T Y, Helen D, Tsun LC, et al. Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia. Cancer Res 2002; 62: 6451-6455.
    • (2002) Cancer Res , vol.62 , pp. 6451-6455
    • Siu, T.Y.1    Helen, D.2    Tsun, L.C.3
  • 31
    • 0030846104 scopus 로고    scopus 로고
    • Prognostic implications of c-Ki-ras2 mutations in patients with advanced colorectal cancer treated with 5-fluorouracil and interferon: A study of the Eastern Cooperative Oncology Group (EST2292)
    • Wadler S, Bajaj R, Neuberg D, Agarwal V, Haynes H, Benson AB. Prognostic implications of c-Ki-ras2 mutations in patients with advanced colorectal cancer treated with 5-fluorouracil and interferon: a study of the Eastern Cooperative Oncology Group (EST2292). Cancer J Sci Am 1997; 3: 284-288.
    • (1997) Cancer J Sci Am , vol.3 , pp. 284-288
    • Wadler, S.1    Bajaj, R.2    Neuberg, D.3    Agarwal, V.4    Haynes, H.5    Benson, A.B.6
  • 32
    • 0026658820 scopus 로고
    • K-ras point mutations in human colorectal carcinomas: Relation to aneuploidy and metastasis
    • Suchy B, Zietz C, Rabes HM. K-ras point mutations in human colorectal carcinomas: relation to aneuploidy and metastasis. Int J Cancer 1992; 52: 30-33.
    • (1992) Int J Cancer , vol.52 , pp. 30-33
    • Suchy, B.1    Zietz, C.2    Rabes, H.M.3
  • 34
    • 74549208605 scopus 로고    scopus 로고
    • KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradio-therapy
    • Gaedcke J, Grade M, Jung K, et al. KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradio-therapy. Radiother Oncol 2010; 94: 76-81.
    • (2010) Radiother Oncol , vol.94 , pp. 76-81
    • Gaedcke, J.1    Grade, M.2    Jung, K.3
  • 35
    • 76049098292 scopus 로고    scopus 로고
    • Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases
    • Baldus SE, Schaefer KL, Engers R, Hartleb D, Stoecklein NH, Gab-bert HE. Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases. Clin Cancer Res 2010; 16: 790-799.
    • (2010) Clin Cancer Res , vol.16 , pp. 790-799
    • Baldus, S.E.1    Schaefer, K.L.2    Engers, R.3    Hartleb, D.4    Stoecklein, N.H.5    Gab-Bert, H.E.6
  • 36
    • 78651241644 scopus 로고    scopus 로고
    • Colorectal cancer molecular biology moves into clinical practice
    • Pritchard CC, Grady WM. Colorectal cancer molecular biology moves into clinical practice. Gut 2011; 60: 116-129.
    • (2011) Gut , vol.60 , pp. 116-129
    • Pritchard, C.C.1    Grady, W.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.