Detection of BRAF mutations in colorectal tumours and peritoneal washings using a mismatch ligation assay

Journal of Clinical Pathology

Volumn 58, Issue 4, 2005, Pages 372-375

  Busby, K ^a   Morris, A ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE;

ADULT; AGED; ANALYTIC METHOD; ARTICLE; ASSAY; CANCER STAGING; CELL ISOLATION; CELL MUTANT; CODON; COLORECTAL TUMOR; CONTROLLED STUDY; DILUTION; DNA DETERMINATION; EXON; FEMALE; GENE AMPLIFICATION; GENE MUTATION; HUMAN; HUMAN CELL; MALE; MISMATCH LIGATION ASSAY; PERITONEUM LAVAGE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

AGED; ASCITIC FLUID; BASE SEQUENCE; COLORECTAL NEOPLASMS; DNA, NEOPLASM; FEMALE; HUMANS; MALE; MIDDLE AGED; MUTATION; NEOPLASM PROTEINS; NEOPLASM STAGING; NUCLEIC ACID AMPLIFICATION TECHNIQUES; PERITONEAL LAVAGE; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS B-RAF;

EID: 17144372612     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.2004.018655     Document Type: Article

References (12)

1. Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature 2002;417:949-54.
2. Kumar R, Angelini S, Hemminki K. Activating BRAF and N-Ras mutations in sporadic primary melanomas: an inverse association with allelic loss on chromosome 9. Oncogene 2003;22:9217-24.
3. Wang LCJ, Winters JL, Guenther JC, et al. BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair. Cancer Res 2003;63:5209-12.
4. Rajagopalan H, Bardelli A, Lengauer C, et al. Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status. Nature 2002;418:934.
5. Yuen ST, Davies H, Chan TL, et al. Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia. Cancer Res 2002;62:6451-5.
6. Landegren U, Kauser R, Sanders J, et al. A ligase-mediated gene detection technique. Science 1988;241:1077-80.
7. Dong SM, Traverso G, Johnson C, et al. Detecting colorectal cancer in stool with the use of multiple genetic targets. J Natl Cancer Inst 2001;93:858-65.
8. Jen J, Powell SM, Papadopoulos N, et al. Molecular determinants of dysplasia in colorectal lesions. Cancer Res 1994;54:5523-6.
9. Sanchez-Cespedes M, Esteller M, Hibi K, et al. Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence. Clin Cancer Res 1999;5:2450-4.
10. Hibi K, Robinson CR, Booker S, et al. Molecular detection of genetic alterations in the serum of colorectal cancer patients. Cancer Res 1998;58:1405-7.
11. Hibi K, Nakayama H, Yamazaki T, et al. Detection of mitochondrial DNA alterations in primary tumors and corresponding serum of colorectal cancer patients. Int J Cancer 2001;94:429-31.
12. Miltenyi S, Muller W, Weichel W, et al. High gradient magnetic cell separation with MACS. Cytometry 1990;11:231-8.