In vivo imaging of unstained tissues using long gradient index lens multiphoton endoscopic systems

Biomedical Optics Express

Volumn 3, Issue 5, 2012, Pages 1077-1085

  Huland, David M ^a   Brown, Christopher M ^a   Howard, Scott S ^a,b   Ouzounov, Dimitre G ^a   Pavlova, Ina ^a,c   Wang, Ke ^a   Rivera, David R ^a   Webb, Watt W ^a   Xu, Chris ^a  

^a School of Operations Research and Industrial Engineering   (United States)

^b University of Notre Dame   (United States)

^c Rice University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTOLOGY; PORTABLE EQUIPMENT; TISSUE;

4-FRAMES; AXIAL RESOLUTIONS; ENDOSCOPIC SYSTEMS; FIELD OF VIEWS; GRADIENT INDEX LENS; GRIN LENS; IN-VIVO IMAGES; IN-VIVO IMAGING; MULTIPHOTON IMAGING; MULTIPHOTONS; PORTABLE DEVICE;

ENDOSCOPY;

RATTUS;

EID: 84863913024     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.3.001077     Document Type: Article

References (29)

1. W. Denk, J. H. Strickler, and W. W. Webb. "Two-photon laser scanning fluorescence microscopy," Science 248(4951), 73-76 (1990).
2. S. J. Lin, S. H. Jee, C. J. Kuo, R. J. Wu, W. C. Lin, J. S. Chen, Y. H. Liao, C. J. Hsu, T. F. Tsai, Y. F. Chen, and C. Y. Dong. "Discrimination of basal cell carcinoma from normal dermal stroma by quantitative multiphoton imaging," Opt. Lett. 31(18), 2756-2758 (2006).
3. S. Mukherjee, J. S. Wysock, C. K. Ng, M. Akhtar, S. Perner, M. M. Lee, M. A. Rubin, F. R. Maxfield, W. W. Webb, and D. S. Scherr. "Human bladder cancer diagnosis using Multiphoton microscopy," Proc. SPIE 7161, 716117, 716117-10 (2009).
4. I. Pavlova, K. R. Hume, S. A. Yazinski, J. Flanders, T. L. Southard, R. S. Weiss, and W. W. Webb. "Multiphoton microscopy and microspectroscopy for diagnostics of inflammatory and neoplastic lung," J. Biomed. Opt. 17(3), 036014 (2012).
5. M. C. Skala, J. M. Squirrell, K. M. Vrotsos, J. C. Eickhoff, A. Gendron-Fitzpatrick, K. W. Eliceiri, and N. Ramanujam. "Multiphoton microscopy of endogenous fluorescence differentiates normal, precancerous, and cancerous squamous epithelial tissues," Cancer Res. 65(4), 1180-1186 (2005).
6. C. C. Wang, F. C. Li, R. J. Wu, V. A. Hovhannisyan, W. C. Lin, S. J. Lin, P. T. So, and C. Y. Dong. "Differentiation of normal and cancerous lung tissues by multiphoton imaging," J. Biomed. Opt. 14(4), 044034 (2009).
7. P. Wilder-Smith, K. Osann, N. Hanna, N. El-Abbadi, M. Brenner, D. Messadi, and T. Krasieva. "In vivo multiphoton fluorescence imaging: a novel approach to oral malignancy," Lasers Surg. Med. 35(2), 96-103 (2004).
8. D. Kobat, M. E. Durst, N. Nishimura, A. W. Wong, C. B. Schaffer, and C. Xu. "Deep tissue multiphoton microscopy using longer wavelength excitation," Opt. Express 17(16), 13354-13364 (2009).
9. D. Kobat, N. G. Horton, and C. Xu. "In vivo two-photon microscopy to 1.6-mm depth in mouse cortex," J. Biomed. Opt. 16(10), 106014 (2011).
10. L. Fu, A. Jain, C. Cranfield, H. Xie, and M. Gu. "Three-dimensional nonlinear optical endoscopy," J. Biomed. Opt. 12(4), 040501 (2007).
11. M. T. Myaing, D. J. MacDonald, and X. Li. "Fiber-optic scanning two-photon fluorescence endoscope," Opt. Lett. 31(8), 1076-1078 (2006).
12. D. R. Rivera, C. M. Brown, D. G. Ouzounov, I. Pavlova, D. Kobat, W. W. Webb, and C. Xu. "Compact and flexible raster scanning multiphoton endoscope capable of imaging unstained tissue," Proc. Natl. Acad. Sci. U.S.A. 108(43), 17598-17603 (2011).
13. S. Tang, W. Jung, D. McCormick, T. Xie, J. Su, Y. C. Ahn, B. J. Tromberg, and Z. Chen. "Design and implementation of fiber-based multiphoton endoscopy with microelectromechanical systems scanning," J. Biomed. Opt. 14(3), 034005 (2009).
14. Y. Wu, Y. Leng, J. Xi, and X. Li. "Scanning all-fiber-optic endomicroscopy system for 3D nonlinear optical imaging of biological tissues," Opt. Express 17(10), 7907-7915 (2009).
15. E. J. Seibel and Q. Y. Smithwick. "Unique features of optical scanning, single fiber endoscopy," Lasers Surg. Med. 30(3), 177-183 (2002).
16. D. R. Rivera, C. M. Brown, D. G. Ouzounov, W. W. Webb, and C. Xu. "Use of a lensed fiber for a large-field-of-view, high-resolution, fiber-scanning microendoscope," Opt. Lett. 37(5), 881-883 (2012).
17. D. R. Rivera, C. M. Brown, D. G. Ouzounov, W. W. Webb, and C. Xu. "Multifocal multiphoton endoscope," Opt. Lett. 37(8), 1349-1351 (2012).
18. C. M. Brown, D. R. Rivera, I. Pavlova, D. G. Ouzounov, W. O. Williams, S. Mohanan, W. W. Webb, and C. Xu. "In vivo imaging of unstained tissues using a compact and flexible multiphoton microendoscope," J. Biomed. Opt. 17(4), 040505 (2012).
19. B. A. Flusberg, J. C. Jung, E. D. Cocker, E. P. Anderson, and M. J. Schnitzer. "In vivo brain imaging using a portable 3.9 gram two-photon fluorescence microendoscope," Opt. Lett. 30(17), 2272-2274 (2005).
20. M. J. Levene, D. A. Dombeck, K. A. Kasischke, R. P. Molloy, and W. W. Webb. "In vivo multiphoton microscopy of deep brain tissue," J. Neurophysiol. 91(4), 1908-1912 (2004).
21. J. C. Jung, A. D. Mehta, E. Aksay, R. Stepnoski, and M. J. Schnitzer. "In vivo mammalian brain imaging using one- and two-photon fluorescence microendoscopy," J. Neurophysiol. 92(5), 3121-3133 (2004).
22. J. C. Jung and M. J. Schnitzer. "Multiphoton endoscopy," Opt. Lett. 28(11), 902-904 (2003).
23. K. König, A. Ehlers, I. Riemann, S. Schenkl, R. Bückle, and M. Kaatz. "Clinical two-photon microendoscopy," Microsc. Res. Tech. 70(5), 398-402 (2007).
24. R. S. Pillai, D. Lorenser, and D. D. Sampson. "Deep-tissue access with confocal fluorescence microendoscopy through hypodermic needles," Opt. Express 19(8), 7213-7221 (2011).
25. Q. T. Nguyen, P. S. Tsai, and D. Kleinfeld. "MPScope: a versatile software suite for multiphoton microscopy," J. Neurosci. Methods 156(1/2), 351-359 (2006).
26. M. E. Durst, D. Kobat, and C. Xu. "Tunable dispersion compensation by a rotating cylindrical lens," Opt. Lett. 34(8), 1195-1197 (2009).
27. L. P. Gartner and J. L. Hiatt, Color Textbook of Histology (W.B. Saunders, Philadelphia, 2001).
28. J. M. Dela Cruz, J. D. McMullen, R. M. Williams, and W. R. Zipfel. "Feasibility of using multiphoton excited tissue autofluorescence for in vivo human histopathology," Biomed. Opt. Express 1(5), 1320-1330 (2010).
29. R. Ramasamy, J. Sterling, E. S. Fisher, P. S. Li, M. Jain, B. D. Robinson, M. Shevchuck, D. Huland, C. Xu, S. Mukherjee, and P. N. Schlegel. "Identification of spermatogenesis with multiphoton microscopy: an evaluation in a rodent model," J. Urol. 186(6), 2487-2492 (2011).