Temporal expression of the PGE2 synthetic system in the kidney is associated with the time frame of renal developmental vulnerability to cyclooxygenase-2 inhibition

American Journal of Physiology - Renal Physiology

Volumn 303, Issue 2, 2012, Pages

  Frölich, Stefanie ^a   Olliges, Anke ^a   Kern, Niklas ^a   Schreiber, Yannik ^a   Narumiya, Shuh ^b   Nüsing, Rolf M ^a  

^a GOETHE UNIVERSITY   (Germany)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Nephrogenesis; NSAID; PGE synthase; Prostaglandins

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; MESSENGER RNA; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; 5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; ISOMERASE; LACTONE; PROSTAGLANDIN E RECEPTOR 1; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; PYRAZOLE DERIVATIVE; ROFECOXIB; SULFONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; GLOMERULUS; IMMUNOHISTOCHEMISTRY; KIDNEY CORTEX; KIDNEY DEVELOPMENT; KIDNEY PARENCHYMA; KIDNEY SIZE; MALE; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; ANIMAL; ANIMAL MODEL; C57BL MOUSE; DRUG EFFECT; GENETICS; GROWTH, DEVELOPMENT AND AGING; KIDNEY; METABOLISM; MOUSE MUTANT; TIME;

ANIMALS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; FEMALE; INTRAMOLECULAR OXIDOREDUCTASES; KIDNEY; LACTONES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, ANIMAL; PYRAZOLES; RECEPTORS, PROSTAGLANDIN E, EP1 SUBTYPE; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; SULFONES; TIME FACTORS;

EID: 84863888237     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00418.2011     Document Type: Article

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