Extracellular human immunodeficiency virus type 1 viral protein R causes reductions in astrocytic ATP and glutathione levels compromising the antioxidant reservoir

Virus Research

Volumn 167, Issue 2, 2012, Pages 358-369

  Ferrucci, Adriano ^a,b   Nonnemacher, Michael R ^b   Cohen, Éric A ^c,d   Wigdahl, Brian ^b  

^a DREXEL UNIVERSITY   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Astrocytes; ATP; Glutathione; HIV 1 induced neuropathogenesis; Oxidative stress; Vpr

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; GLUTATHIONE; GLUTATHIONE DISULFIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VIRUS ANTIBODY; VPR PROTEIN; VPR PROTEIN ANTIBODY;

ARTICLE; ASTROCYTE; ASTROCYTOMA; CELL LINE; CELL STRAIN HEK293; CELL SURVIVAL; CULTURE MEDIUM; DOWN REGULATION; FETUS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; RESERVOIR;

ADENOSINE TRIPHOSPHATE; ANTIOXIDANTS; ASTROCYTES; CELL LINE; CULTURE MEDIA, CONDITIONED; CYTOPLASM; GENE PRODUCTS, VPR; GLUTATHIONE; HIV-1; HUMANS; VIRULENCE FACTORS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84863872696     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2012.06.002     Document Type: Article

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