Dissecting structural basis of the unique substrate selectivity of human enteropeptidase catalytic subunit

Journal of Biomolecular Structure and Dynamics

Volumn 30, Issue 1, 2012, Pages 62-73

  Ostapchenko, Valeriy G ^a   Gasparian, Marine E ^a   Kosinsky, Yurij A ^a   Efremov, Roman G ^a   Dolgikh, Dmitry A ^a   Kirpichnikov, Mikhail P ^a  

^a SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

Active site; Enteropeptidase; Enzymatic catalysis; Molecular modeling; Substrate selectivity

Indexed keywords

ARGININE; ENTEROPEPTIDASE; GLUTAMINE; LYSINE; N BENZOYLARGININE 2 NAPHTHYLAMIDE; ASPARTIC ACID; PEPTIDE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; COMPUTER MODEL; COMPUTER PROGRAM; COW; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; GENE MUTATION; HUMAN; HYDROLYSIS; HYDROPHOBICITY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; SPECIES DIFFERENCE; CATALYSIS; CONTROLLED STUDY; ENZYME SUBSTRATE; ENZYME SUBUNIT; MUTATION; ORTHOLOGY; PROTEIN HYDROLYSIS; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; CATTLE; ENTEROPEPTIDASE; HUMANS; HYDROLYSIS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

ANIMALIA; BOVINAE;

EID: 84863870147     PISSN: 07391102     EISSN: None     Source Type: Journal    
DOI: 10.1080/07391102.2012.674249     Document Type: Article

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