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Volumn 59, Issue 2, 2012, Pages 150-159

Diagnostic performance of Des-γ-carboxy prothrombin (DCP) for Hepatocellular carcinoma: A Bivariate Meta-analysis

Author keywords

Des carboxy prothrombin; Diagnostic test; Hepatocellular carcinoma; Pooled analysis; Sandwich ELISA

Indexed keywords

DECARBOXYPROTHROMBIN; BIOLOGICAL MARKER; PROTEIN PRECURSOR; PROTHROMBIN; TUMOR MARKER;

EID: 84863856216     PISSN: 00282685     EISSN: 13384317     Source Type: Journal    
DOI: 10.4149/neo_2012_020     Document Type: Article
Times cited : (20)

References (45)
  • 1
    • 7044229778 scopus 로고    scopus 로고
    • Primary liver cancer: Worldwide incidence and trends
    • BOSCH FX, RIBES J, DIAZ M, CLERIES R. Primary liver cancer: worldwide incidence and trends. Gastroenterology 2004; 127: S5-S16. http://dx.doi.org/10.1053/j.gastro.2004.09.011
    • (2004) Gastroenterology , vol.127
    • Bosch, F.X.1    Ribes, J.2    Diaz, M.3    Cleries, R.4
  • 2
    • 0035888074 scopus 로고    scopus 로고
    • Estimating the world cancer burden: Globocan 2000
    • PARKIN DM, BRAY F, FERLAY J, PISANI P. Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001; 94: 153-156. http://dx.doi.org/10.1002/ijc.1440
    • (2001) Int J Cancer , vol.94 , pp. 153-156
    • Parkin, D.M.1    Bray, F.2    Ferlay, J.3    Pisani, P.4
  • 3
    • 0028295893 scopus 로고
    • Current treatment modalities for hepatocellular carcinoma
    • FARMER DG, ROSOVE MH, SHAKED A, BUSUTTIL RW. Current treatment modalities for hepatocellular carcinoma. Ann Surg 1994; 219: 236-247.
    • (1994) Ann Surg , vol.219 , pp. 236-247
    • Farmer, D.G.1    Rosove, M.H.2    Shaked, A.3    Busuttil, R.W.4
  • 4
    • 28844480321 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma
    • BRUIX J, SHERMAN M. Management of hepatocellular carcinoma. Hepatology 2005; 42: 1208-1236. http://dx.doi. org/10.1002/hep.20933
    • (2005) Hepatology , vol.42 , pp. 1208-1236
    • Bruix, J.1    Sherman, M.2
  • 5
    • 20344367769 scopus 로고    scopus 로고
    • Resection and liver transplantation for hepatocellular carcinoma
    • LLOVET JM, SCHWARTZ M, MAZZAFERRO V. Resection and liver transplantation for hepatocellular carcinoma. Semin Liver Dis 2005; 25: 181-200.
    • (2005) Semin Liver Dis , vol.25 , pp. 181-200
    • Llovet, J.M.1    Schwartz, M.2    Mazzaferro, V.3
  • 6
    • 0022641584 scopus 로고
    • Early detection of hepatocellular carcinoma in patients with chronic type B hepatitis. A prospective study
    • LIAW YF, TAI DI, CHU CM, LIN DY, SHEEN IS et al. Early detection of hepatocellular carcinoma in patients with chronic type B hepatitis. A prospective study. Gastroenterology 1986; 90: 263-267.
    • (1986) Gastroenterology , vol.90 , pp. 263-267
    • Liaw, Y.F.1    Tai, D.I.2    Chu, C.M.3    Lin, D.Y.4    Sheen, I.S.5
  • 7
    • 3843125293 scopus 로고    scopus 로고
    • Randomized controlled trial of screening for hepatocellular carcinoma
    • ZHANG BH, YANG BH, TANG ZY. Randomized controlled trial of screening for hepatocellular carcinoma. J Cancer Res Clin Oncol 2004; 130: 417-422.
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 417-422
    • Zhang, B.H.1    Yang, B.H.2    Tang, Z.Y.3
  • 9
    • 0035722375 scopus 로고    scopus 로고
    • Surveillance for hepatocellular carcinoma in patients with chronic viral hepatitis in the United States of America
    • TONG MJ, BLATT LM, KAO VW. Surveillance for hepatocellular carcinoma in patients with chronic viral hepatitis in the United States of America. J Gastroenterol Hepatol 2001; 16: 553-559. http://dx.doi.org/10.1046/j.1440-1746.2001.02470.x
    • (2001) J Gastroenterol Hepatol , vol.16 , pp. 553-559
    • Tong, M.J.1    Blatt, L.M.2    Kao, V.W.3
  • 10
    • 0021337575 scopus 로고
    • Serum alpha-fetoprotein in the early stage of human hepatocellular carcinoma
    • CHEN DS, SUNG JL, SHEU JC, LAI MY, HOW SW et al. Serum alpha-fetoprotein in the early stage of human hepatocellular carcinoma. Gastroenterology 1984; 86: 1404-1409.
    • (1984) Gastroenterology , vol.86 , pp. 1404-1409
    • Chen, D.S.1    Sung, J.L.2    Sheu, J.C.3    Lai, M.Y.4    How, S.W.5
  • 11
    • 0024439897 scopus 로고
    • Elevations in serum alpha-fetoprotein levels in patients with chronic hepatitis B
    • DI BISCEGLIE AM, HOOFNAGLE JH. Elevations in serum alpha-fetoprotein levels in patients with chronic hepatitis B. Cancer 1989; 64: 2117-2120. http://dx.doi.org/10.1002/1097-014 2(19891115)64:10<2117::AID-CNCR2820641024>3.0.CO;2-7
    • (1989) Cancer , vol.64 , pp. 2117-2120
    • Di Bisceglie, A.M.1    Hoofnagle, J.H.2
  • 12
    • 0021273094 scopus 로고
    • Des-gamma-carboxy (abnormal) prothrombin as a serum marker of primary hepatocellular carcinoma
    • LIEBMAN HA, FURIE BC, TONG MJ, BLANCHARD RA, LO KJ et al. Des-gamma-carboxy (abnormal) prothrombin as a serum marker of primary hepatocellular carcinoma. N Engl J Med 1984; 310: 1427-1431. http://dx.doi.org/10.1056/NEJM198405313102204
    • (1984) N Engl J Med , vol.310 , pp. 1427-1431
    • Liebman, H.A.1    Furie, B.C.2    Tong, M.J.3    Blanchard, R.A.4    Lo, K.J.5
  • 13
    • 0034856294 scopus 로고    scopus 로고
    • Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver
    • BRUIX J, SHERMAN M, LLOVET JM, BEAUGRAND M, LENCIONI R et al. Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver. J Hepatol 2001; 35: 421-430.
    • (2001) J Hepatol , vol.35 , pp. 421-430
    • Bruix, J.1    Sherman, M.2    Llovet, J.M.3    Beaugrand, M.4    Lencioni, R.5
  • 14
    • 2942700307 scopus 로고    scopus 로고
    • The development of QUADAS: A tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews
    • WHITING P, RUTJES AW, REITSMA JB, BOSSUYT PM, KLEIJNEN J. The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol 2003; 3: 25. http://dx.doi.org/10.1186/1471-2288-3-25
    • (2003) BMC Med Res Methodol , vol.3 , pp. 25
    • Whiting, P.1    Rutjes, A.W.2    Reitsma, J.B.3    Bossuyt, P.M.4    Kleijnen, J.5
  • 15
    • 23944444623 scopus 로고    scopus 로고
    • No role for quality scores in systematic reviews of diagnostic accuracy studies
    • WHITING P, HARBORD R, KLEIJNEN J. No role for quality scores in systematic reviews of diagnostic accuracy studies. BMC Med Res Methodol 2005; 5: 19. http://dx.doi. org/10.1186/1471-2288-5-19
    • (2005) BMC Med Res Methodol , vol.5 , pp. 19
    • Whiting, P.1    Harbord, R.2    Kleijnen, J.3
  • 16
    • 24944498883 scopus 로고    scopus 로고
    • Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews
    • REITSMA JB, GLAS AS, RUTJES AW, SCHOLTEN RJ, BOSSUYT PM et al. Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. J Clin Epidemiol 2005; 58: 982-990. http://dx.doi. org/10.1016/j.jclinepi.2005.02.022
    • (2005) J Clin Epidemiol , vol.58 , pp. 982-990
    • Reitsma, J.B.1    Glas, A.S.2    Rutjes, A.W.3    Scholten, R.J.4    Bossuyt, P.M.5
  • 17
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • HIGGINS JP, THOMPSON SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21: 1539-1558. http://dx.doi. org/10.1002/sim.1186
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 18
    • 52949141475 scopus 로고    scopus 로고
    • An empirical comparison of methods for meta-analysis of diagnostic accuracy showed hierarchical models are necessary
    • HARBORD RM, WHITING P, STERNE JA, EGGER M, DEEKS JJ et al. An empirical comparison of methods for meta-analysis of diagnostic accuracy showed hierarchical models are necessary. J Clin Epidemiol 2008; 61: 1095-1103. http://dx.doi.org/10.1016/j.jclinepi.2007.09.013
    • (2008) J Clin Epidemiol , vol.61 , pp. 1095-1103
    • Harbord, R.M.1    Whiting, P.2    Sterne, J.A.3    Egger, M.4    Deeks, J.J.5
  • 19
    • 23644432857 scopus 로고    scopus 로고
    • The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed
    • DEEKS JJ, MACASKILL P, IRWIG L. The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed. J Clin Epidemiol 2005; 58: 882-893. http://dx.doi.org/10.1016/j.jclinepi.2005.01.016
    • (2005) J Clin Epidemiol , vol.58 , pp. 882-893
    • Deeks, J.J.1    Macaskill, P.2    Irwig, L.3
  • 20
    • 0035657488 scopus 로고    scopus 로고
    • Efficient diagnostic test sequence: Applications of the probability-modifying plot
    • SEVERENS JL, SONKE G, LAHEIJ RJ, VERBEEK AL, DE VRIES ROBBE PF. Efficient diagnostic test sequence: applications of the probability-modifying plot. J Clin Epidemiol 2001; 54: 1228-1237. http://dx.doi.org/10.1016/S0895-4356(01)00391-2
    • (2001) J Clin Epidemiol , vol.54 , pp. 1228-1237
    • Severens, J.L.1    Sonke, G.2    Laheij, R.J.3    Verbeek, A.L.4    De Vries Robbe, P.F.5
  • 21
    • 0016866107 scopus 로고
    • LETTER: Nomogram for Bayes theorem
    • FAGAN TJ. LETTER: Nomogram for Bayes theorem. N Engl J Med 1975; 293: 257. http://dx.doi.org/10.1056/NEJM197507312930513
    • (1975) N Engl J Med , vol.293 , pp. 257
    • Fagan, T.J.1
  • 22
    • 0038028611 scopus 로고    scopus 로고
    • A likelihood ratio approach to meta-analysis of diagnostic studies
    • STENGEL D, BAUWENS K, SEHOULI J, EKKERNKAMP A, PORZSOLT F. A likelihood ratio approach to meta-analysis of diagnostic studies. J Med Screen 2003; 10: 47-51. http://dx.doi. org/10.1258/096914103321610806
    • (2003) J Med Screen , vol.10 , pp. 47-51
    • Stengel, D.1    Bauwens, K.2    Sehouli, J.3    Ekkernkamp, A.4    Porzsolt, F.5
  • 23
    • 78549285667 scopus 로고    scopus 로고
    • Alpha-1-acid glycoprotein as potential biomarker for alpha-fetoprotein-low hepatocellular carcinoma
    • BACHTIAR I, KHENG V, WIBOWO GA, GANI RA, HASAN I et al. Alpha-1-acid glycoprotein as potential biomarker for alpha-fetoprotein-low hepatocellular carcinoma. BMC Res Notes 2010; 3: 319.
    • (2010) BMC Res Notes , vol.3 , pp. 319
    • Bachtiar, I.1    Kheng, V.2    Wibowo, G.A.3    Gani, R.A.4    Hasan, I.5
  • 24
    • 67651222773 scopus 로고    scopus 로고
    • Diagnostic role and correlation with staging systems of PIVKA-II compared with AFP
    • BAEK YH, LEE JH, JANG JS, LEE SW, HAN JY et al. Diagnostic role and correlation with staging systems of PIVKA-II compared with AFP. Hepatogastroenterology 2009; 56: 763-767.
    • (2009) Hepatogastroenterology , vol.56 , pp. 763-767
    • Baek, Y.H.1    Lee, J.H.2    Jang, J.S.3    Lee, S.W.4    Han, J.Y.5
  • 25
    • 48549106668 scopus 로고    scopus 로고
    • AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in nonalcoholic and alcoholic fatty liver disease
    • BEALE G, CHATTOPADHYAY D, GRAY J, STEWART S, HUDSON M et al. AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in nonalcoholic and alcoholic fatty liver disease. BMC Cancer 2008; 8: 200. http://dx.doi.org/10.1186/1471-2407-8-200
    • (2008) BMC Cancer , vol.8 , pp. 200
    • Beale, G.1    Chattopadhyay, D.2    Gray, J.3    Stewart, S.4    Hudson, M.5
  • 26
    • 0038236531 scopus 로고    scopus 로고
    • Diagnostic value of protein induced by vitamin K absence (PIVKAII) and hepatoma-specific band of serum gamma-glutamyl transferase (GGTII) as hepatocellular carcinoma markers complementary to alpha-fetoprotein
    • CUI R, HE J, ZHANG F, WANG B, DING H et al. Diagnostic value of protein induced by vitamin K absence (PIVKAII) and hepatoma-specific band of serum gamma-glutamyl transferase (GGTII) as hepatocellular carcinoma markers complementary to alpha-fetoprotein. Br J Cancer 2003; 88: 1878-1882. http://dx.doi.org/10.1038/sj.bjc.6601018
    • (2003) Br J Cancer , vol.88 , pp. 1878-1882
    • Cui, R.1    He, J.2    Zhang, F.3    Wang, B.4    Ding, H.5
  • 27
    • 51849127949 scopus 로고    scopus 로고
    • Des-gamma-carboxyprothrombin, alpha-fetoprotein and AFP-L3 in patients with chronic hepatitis, cirrhosis and hepatocellular carcinoma
    • DURAZO FA, BLATT LM, COREY WG, LIN JH, HAN S et al. Des-gamma-carboxyprothrombin, alpha-fetoprotein and AFP-L3 in patients with chronic hepatitis, cirrhosis and hepatocellular carcinoma. J Gastroenterol Hepatol 2008; 23: 1541-1548. http://dx.doi.org/10.1111/j.1440-1746.2008.05395.x
    • (2008) J Gastroenterol Hepatol , vol.23 , pp. 1541-1548
    • Durazo, F.A.1    Blatt, L.M.2    Corey, W.G.3    Lin, J.H.4    Han, S.5
  • 28
    • 0030863067 scopus 로고    scopus 로고
    • Usefulness of ED036 kit for measuring serum PIVKA-II levels in small hepatocellular carcinoma
    • KUROMATSU R, TANAKA M, SHIMAUCHI Y, SHIMADA M, TANIKAWA K et al. Usefulness of ED036 kit for measuring serum PIVKA-II levels in small hepatocellular carcinoma. J Gastroenterol 1997; 32: 507-512. http://dx.doi.org/10.1007/BF02934091
    • (1997) J Gastroenterol , vol.32 , pp. 507-512
    • Kuromatsu, R.1    Tanaka, M.2    Shimauchi, Y.3    Shimada, M.4    Tanikawa, K.5
  • 29
    • 75449103932 scopus 로고    scopus 로고
    • Des-gamma-carboxy prothrombin and alpha-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma
    • LOK AS, STERLING RK, EVERHART JE, WRIGHT EC, HOEFS JC et al. Des-gamma-carboxy prothrombin and alpha-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma. Gastroenterology 2010; 138: 493-502. http://dx.doi.org/10.1053/j.gastro.2009.10.031
    • (2010) Gastroenterology , vol.138 , pp. 493-502
    • Lok, A.S.1    Sterling, R.K.2    Everhart, J.E.3    Wright, E.C.4    Hoefs, J.C.5
  • 30
    • 67649305155 scopus 로고    scopus 로고
    • Alpha-fetoprotein, des-gamma carboxyprothrombin, and lectin-bound alpha-fetoprotein in early hepatocellular carcinoma
    • MARRERO JA, FENG Z, WANG Y, NGUYEN MH, BEFELER AS et al. Alpha-fetoprotein, des-gamma carboxyprothrombin, and lectin-bound alpha-fetoprotein in early hepatocellular carcinoma. Gastroenterology 2009; 137: 110-118.
    • (2009) Gastroenterology , vol.137 , pp. 110-118
    • Marrero, J.A.1    Feng, Z.2    Wang, Y.3    Nguyen, M.H.4    Befeler, A.S.5
  • 31
    • 0037698789 scopus 로고    scopus 로고
    • Des-gamma carboxyprothrombin can differentiate hepatocellular carcinoma from nonmalignant chronic liver disease in american patients
    • MARRERO JA, SU GL, WEI W, EMICK D, CONJEEVARAM HS et al. Des-gamma carboxyprothrombin can differentiate hepatocellular carcinoma from nonmalignant chronic liver disease in american patients. Hepatology 2003; 37: 1114-1121. http://dx.doi.org/10.1053/jhep.2003.50195
    • (2003) Hepatology , vol.37 , pp. 1114-1121
    • Marrero, J.A.1    Su, G.L.2    Wei, W.3    Emick, D.4    Conjeevaram, H.S.5
  • 32
    • 0032080912 scopus 로고    scopus 로고
    • The usefulness of determining des-gamma-carboxy prothrombin by sensitive enzyme immunoassay in the early diagnosis of patients with hepatocellular carcinoma
    • MITA Y, AOYAGI Y, YANAGI M, SUDA T, SUZUKI Y et al. The usefulness of determining des-gamma-carboxy prothrombin by sensitive enzyme immunoassay in the early diagnosis of patients with hepatocellular carcinoma. Cancer 1998; 82: 1643-1648. http://dx.doi.org/10.1002/(SICI)1097-0142(19980501)82:9<1643::AID-CNCR8>3.0.CO;2-B
    • (1998) Cancer , vol.82 , pp. 1643-1648
    • Mita, Y.1    Aoyagi, Y.2    Yanagi, M.3    Suda, T.4    Suzuki, Y.5
  • 33
    • 33748366782 scopus 로고    scopus 로고
    • Sensitivity and specificity of des-gamma-carboxy prothrombin for diagnosis of patients with hepatocellular carcinomas varies according to tumor size
    • NAKAMURA S, NOUSO K, SAKAGUCHI K, ITO YM, OHASHI Y et al. Sensitivity and specificity of des-gamma-carboxy prothrombin for diagnosis of patients with hepatocellular carcinomas varies according to tumor size. Am J Gastroenterol 2006; 101: 2038-2043. http://dx.doi. org/10.1111/j.1572-0241.2006.00681.x
    • (2006) Am J Gastroenterol , vol.101 , pp. 2038-2043
    • Nakamura, S.1    Nouso, K.2    Sakaguchi, K.3    Ito, Y.M.4    Ohashi, Y.5
  • 34
    • 0033048769 scopus 로고    scopus 로고
    • Serum des-gamma-carboxy prothrombin levels determined by a new generation of sensitive immunoassays in patients with small-sized hepatocellular carcinoma
    • NOMURA F, ISHIJIMA M, KUWA K, TANAKA N, NAKAI T et al. Serum des-gamma-carboxy prothrombin levels determined by a new generation of sensitive immunoassays in patients with small-sized hepatocellular carcinoma. Am J Gastroenterol 1999; 94: 650-654. http://dx.doi.org/10.1111/j.1572-0241.1999.00930.x
    • (1999) Am J Gastroenterol , vol.94 , pp. 650-654
    • Nomura, F.1    Ishijima, M.2    Kuwa, K.3    Tanaka, N.4    Nakai, T.5
  • 35
    • 0033557988 scopus 로고    scopus 로고
    • Measurement of serum levels of desgamma-carboxy prothrombin in patients with hepatocellular carcinoma by a revised enzyme immunoassay kit with increased sensitivity
    • OKUDA H, NAKANISHI T, TAKATSU K, SAITO A, HAYASHI N et al. Measurement of serum levels of desgamma-carboxy prothrombin in patients with hepatocellular carcinoma by a revised enzyme immunoassay kit with increased sensitivity. Cancer 1999; 85: 812-818. http://dx.doi. org/10.1002/(SICI)1097-0142(19990215)85:4<812::AIDCNCR8> 3.0.CO;2-O
    • (1999) Cancer , vol.85 , pp. 812-818
    • Okuda, H.1    Nakanishi, T.2    Takatsu, K.3    Saito, A.4    Hayashi, N.5
  • 36
    • 0033457907 scopus 로고    scopus 로고
    • Clinical utility of simultaneous measurement of serum high-sensitivity des-gamma-carboxy prothrombin and Lens culinaris agglutinin A-reactive alpha-fetoprotein in patients with small hepatocellular carcinoma
    • SASSA T, KUMADA T, NAKANO S, UEMATSU T. Clinical utility of simultaneous measurement of serum high-sensitivity des-gamma-carboxy prothrombin and Lens culinaris agglutinin A-reactive alpha-fetoprotein in patients with small hepatocellular carcinoma. Eur J Gastroenterol Hepatol 1999; 11: 1387-1392. http://dx.doi.org/10.1097/00042737-199912000-00008
    • (1999) Eur J Gastroenterol Hepatol , vol.11 , pp. 1387-1392
    • Sassa, T.1    Kumada, T.2    Nakano, S.3    Uematsu, T.4
  • 37
    • 77958089831 scopus 로고    scopus 로고
    • Clinical utility of prothrombin induced by vitamin K absence in the detection of hepatocellular carcinoma in Indian population
    • SHARMA B, SRINIVASAN R, CHAWLA YK, KAPIL S, SAINI N et al. Clinical utility of prothrombin induced by vitamin K absence in the detection of hepatocellular carcinoma in Indian population. Hepatol Int 2010; 4: 569-576. http://dx.doi. org/10.1007/s12072-010-9186-2
    • (2010) Hepatol Int , vol.4 , pp. 569-576
    • Sharma, B.1    Srinivasan, R.2    Chawla, Y.K.3    Kapil, S.4    Saini, N.5
  • 38
    • 58049200257 scopus 로고    scopus 로고
    • Utility of Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein and des-gamma-carboxy prothrombin, alone or in combination, as biomarkers for hepatocellular carcinoma
    • STERLING RK, JEFFERS L, GORDON F, VENOOK AP, REDDY KR et al. Utility of Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein and des-gamma-carboxy prothrombin, alone or in combination, as biomarkers for hepatocellular carcinoma. Clin Gastroenterol Hepatol 2009; 7: 104-113. http://dx.doi.org/10.1016/j.cgh.2008.08.041
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 104-113
    • Sterling, R.K.1    Jeffers, L.2    Gordon, F.3    Venook, A.P.4    Reddy, K.R.5
  • 39
    • 34447260276 scopus 로고    scopus 로고
    • Risk factors for hepatocellular carcinoma may impair the performance of biomarkers: A comparison of AFP, DCP, and AFP-L3
    • VOLK ML, HERNANDEZ JC, SU GL, LOK AS, MARRERO JA. Risk factors for hepatocellular carcinoma may impair the performance of biomarkers: a comparison of AFP, DCP, and AFP-L3. Cancer Biomark 2007; 3: 79-87.
    • (2007) Cancer Biomark , vol.3 , pp. 79-87
    • Volk, M.L.1    Hernandez, J.C.2    Su, G.L.3    Lok, A.S.4    Marrero, J.A.5
  • 40
    • 30644467109 scopus 로고    scopus 로고
    • Usefulness of serum des-gamma-carboxy prothrombin in detection of hepatocellular carcinoma
    • WANG CS, LIN CL, LEE HC, CHEN KY, CHIANG MF et al. Usefulness of serum des-gamma-carboxy prothrombin in detection of hepatocellular carcinoma. World J Gastroenterol 2005; 11: 6115-6119.
    • (2005) World J Gastroenterol , vol.11 , pp. 6115-6119
    • Wang, C.S.1    Lin, C.L.2    Lee, H.C.3    Chen, K.Y.4    Chiang, M.F.5
  • 41
    • 70350686384 scopus 로고    scopus 로고
    • Role of serum prothrombin induced by vitamin K absence or antagonist-II in the early detection of hepatocellular carcinoma in patients with chronic hepatitis B virus infection
    • YOON YJ, HAN KH, KIM DO Y. Role of serum prothrombin induced by vitamin K absence or antagonist-II in the early detection of hepatocellular carcinoma in patients with chronic hepatitis B virus infection. Scand J Gastroenterol 2009; 44: 861-866. http://dx.doi.org/10.1080/00365520902903034
    • (2009) Scand J Gastroenterol , vol.44 , pp. 861-866
    • Yoon, Y.J.1    Han, K.H.2    Kim Do, Y.3
  • 43
    • 40049097359 scopus 로고    scopus 로고
    • Liver cirrhosis
    • SCHUPPAN D, AFDHAL NH. Liver cirrhosis. Lancet 2008; 371: 838-851. http://dx.doi.org/10.1016/S0140-6736(08)60383-9
    • (2008) Lancet , vol.371 , pp. 838-851
    • Schuppan, D.1    Afdhal, N.H.2
  • 44
    • 0028760247 scopus 로고
    • Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group
    • JAESCHKE R, GUYATT GH, SACKETT DL. Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group. JAMA 1994; 271: 703-707. http://dx.doi. org/10.1001/jama.271.9.703
    • (1994) JAMA , vol.271 , pp. 703-707
    • Jaeschke, R.1    Guyatt, G.H.2    Sackett, D.L.3
  • 45
    • 33644763305 scopus 로고    scopus 로고
    • Accuracy of ultrasonography, spiral CT, magnetic resonance, and alpha-fetoprotein in diagnosing hepatocellular carcinoma: A systematic review
    • COLLI A, FRAQUELLI M, CASAZZA G, MASSIRONI S, COLUCCI A et al. Accuracy of ultrasonography, spiral CT, magnetic resonance, and alpha-fetoprotein in diagnosing hepatocellular carcinoma: a systematic review. Am J Gastroenterol 2006; 101: 513-523. http://dx.doi.org/10.1111/j.1572-0241.2006.00467.x
    • (2006) Am J Gastroenterol , vol.101 , pp. 513-523
    • Colli, A.1    Fraquelli, M.2    Casazza, G.3    Massironi, S.4    Colucci, A.5


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