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Volumn 423, Issue 4, 2012, Pages 878-883

In vivo study of breast carcinoma radiosensitization by targeting eIF4E

Author keywords

Breast cancer; EIF4E; PSecX t4EBP1; Radiosensitization; Xenograft

Indexed keywords

INITIATION FACTOR 4E; PROTEIN INHIBITOR; PSECX T4EBP1; UNCLASSIFIED DRUG;

EID: 84863854645     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.06.064     Document Type: Article
Times cited : (10)

References (40)
  • 1
    • 33644889948 scopus 로고    scopus 로고
    • Use of statistics to assess the global burden of breast cancer
    • Parkin D.M., Fernandez L.M. Use of statistics to assess the global burden of breast cancer. Breast J. 2006, 12(Suppl 1):S70-S80.
    • (2006) Breast J. , vol.12 , Issue.SUPPL. 1
    • Parkin, D.M.1    Fernandez, L.M.2
  • 3
    • 14744278795 scopus 로고    scopus 로고
    • Breast cancer: new radiation treatment options
    • 1629-1630, 1636-1638
    • Arthur D.W., Morris M.M., Vicini F.A. Breast cancer: new radiation treatment options. Oncology (Williston Park) 2004, 18:1621-1629. 1629-1630, 1636-1638.
    • (2004) Oncology (Williston Park) , vol.18 , pp. 1621-1629
    • Arthur, D.W.1    Morris, M.M.2    Vicini, F.A.3
  • 4
    • 7744232593 scopus 로고    scopus 로고
    • Breast cancer: improving outcome following adjuvant radiotherapy
    • Violet J.A., Harmer C. Breast cancer: improving outcome following adjuvant radiotherapy. Br. J. Radiol. 2004, 77:811-820.
    • (2004) Br. J. Radiol. , vol.77 , pp. 811-820
    • Violet, J.A.1    Harmer, C.2
  • 6
    • 10244222905 scopus 로고    scopus 로고
    • Radioresistance in carcinoma of the breast
    • Jameel J.K., Rao V.S., Cawkwell L., Drew P.J. Radioresistance in carcinoma of the breast. Breast 2004, 13:452-460.
    • (2004) Breast , vol.13 , pp. 452-460
    • Jameel, J.K.1    Rao, V.S.2    Cawkwell, L.3    Drew, P.J.4
  • 7
    • 0030883848 scopus 로고    scopus 로고
    • PHAS/4E-BPs as regulators of mRNA translation and cell proliferation
    • Lawrence J.J., Abraham R.T. PHAS/4E-BPs as regulators of mRNA translation and cell proliferation. Trends Biochem. Sci. 1997, 22:345-349.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 345-349
    • Lawrence, J.J.1    Abraham, R.T.2
  • 8
    • 0032834055 scopus 로고    scopus 로고
    • EIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation
    • Gingras A.C., Raught B., Sonenberg N. EIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu. Rev. Biochem. 1999, 68:913-963.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 913-963
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 9
    • 41149153346 scopus 로고    scopus 로고
    • The mTOR target 4E-BP1 contributes to differential protein expression during normoxia and hypoxia through changes in mRNA translation efficiency
    • Magagnin M.G., van den Beucken T., Sergeant K., et al. The mTOR target 4E-BP1 contributes to differential protein expression during normoxia and hypoxia through changes in mRNA translation efficiency. Proteomics 2008, 8:1019-1028.
    • (2008) Proteomics , vol.8 , pp. 1019-1028
    • Magagnin, M.G.1    van den Beucken, T.2    Sergeant, K.3
  • 10
    • 0033920969 scopus 로고    scopus 로고
    • Translation initiation factor modifications and the regulation of protein synthesis in apoptotic cells
    • Clemens M.J., Bushell M., Jeffrey I.W., Pain V.M., Morley S.J. Translation initiation factor modifications and the regulation of protein synthesis in apoptotic cells. Cell Death Differ. 2000, 7:603-615.
    • (2000) Cell Death Differ. , vol.7 , pp. 603-615
    • Clemens, M.J.1    Bushell, M.2    Jeffrey, I.W.3    Pain, V.M.4    Morley, S.J.5
  • 11
    • 0034624746 scopus 로고    scopus 로고
    • Inhibition of Myc-dependent apoptosis by eukaryotic translation initiation factor 4E requires cyclin D1
    • Tan A., Bitterman P., Sonenberg N., Peterson M., Polunovsky V. Inhibition of Myc-dependent apoptosis by eukaryotic translation initiation factor 4E requires cyclin D1. Oncogene 2000, 19:1437-1447.
    • (2000) Oncogene , vol.19 , pp. 1437-1447
    • Tan, A.1    Bitterman, P.2    Sonenberg, N.3    Peterson, M.4    Polunovsky, V.5
  • 12
    • 0036195727 scopus 로고    scopus 로고
    • Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency
    • Li S., Sonenberg N., Gingras A.C., et al. Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency. Mol. Cell Biol. 2002, 22:2853-2861.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 2853-2861
    • Li, S.1    Sonenberg, N.2    Gingras, A.C.3
  • 13
    • 0030808698 scopus 로고    scopus 로고
    • Detection of the proto-oncogene eIF4E in surgical margins may predict recurrence in head and neck cancer
    • Nathan C.O., Liu L., Li B.D., Abreo F.W., Nandy I., De Benedetti A. Detection of the proto-oncogene eIF4E in surgical margins may predict recurrence in head and neck cancer. Oncogene 1997, 15:579-584.
    • (1997) Oncogene , vol.15 , pp. 579-584
    • Nathan, C.O.1    Liu, L.2    Li, B.D.3    Abreo, F.W.4    Nandy, I.5    De Benedetti, A.6
  • 14
    • 0039656540 scopus 로고    scopus 로고
    • Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis
    • Rosenwald I.B., Chen J.J., Wang S., Savas L., London I.M., Pullman J. Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis. Oncogene 1999, 18:2507-2517.
    • (1999) Oncogene , vol.18 , pp. 2507-2517
    • Rosenwald, I.B.1    Chen, J.J.2    Wang, S.3    Savas, L.4    London, I.M.5    Pullman, J.6
  • 15
    • 0033031044 scopus 로고    scopus 로고
    • Expression of the eukaryotic translation initiation factors 4E and 2alpha in non-Hodgkin's lymphomas
    • Wang S., Rosenwald I.B., Hutzler M.J., et al. Expression of the eukaryotic translation initiation factors 4E and 2alpha in non-Hodgkin's lymphomas. Am. J. Pathol. 1999, 155:247-255.
    • (1999) Am. J. Pathol. , vol.155 , pp. 247-255
    • Wang, S.1    Rosenwald, I.B.2    Hutzler, M.J.3
  • 16
    • 27544447650 scopus 로고    scopus 로고
    • EIF-4E expression is associated with histopathologic grades in cervical neoplasia
    • Lee J.W., Choi J.J., Lee K.M., et al. EIF-4E expression is associated with histopathologic grades in cervical neoplasia. Hum. Pathol. 2005, 36:1197-1203.
    • (2005) Hum. Pathol. , vol.36 , pp. 1197-1203
    • Lee, J.W.1    Choi, J.J.2    Lee, K.M.3
  • 17
    • 33746206552 scopus 로고    scopus 로고
    • High eIF4E, VEGF, and microvessel density in stage I to III breast cancer
    • 691-692
    • Byrnes K., White S., Chu Q., et al. High eIF4E, VEGF, and microvessel density in stage I to III breast cancer. Ann. Surg. 2006, 243:684-690. 691-692.
    • (2006) Ann. Surg. , vol.243 , pp. 684-690
    • Byrnes, K.1    White, S.2    Chu, Q.3
  • 18
    • 0030867624 scopus 로고    scopus 로고
    • Elevated expression of eIF4E and FGF-2 isoforms during vascularization of breast carcinomas
    • Nathan C.O., Carter P., Liu L., et al. Elevated expression of eIF4E and FGF-2 isoforms during vascularization of breast carcinomas. Oncogene 1997, 15:1087-1094.
    • (1997) Oncogene , vol.15 , pp. 1087-1094
    • Nathan, C.O.1    Carter, P.2    Liu, L.3
  • 19
    • 0030041884 scopus 로고    scopus 로고
    • Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E
    • Rousseau D., Kaspar R., Rosenwald I., Gehrke L., Sonenberg N. Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E. Proc. Natl. Acad. Sci. USA 1996, 93:1065-1070.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1065-1070
    • Rousseau, D.1    Kaspar, R.2    Rosenwald, I.3    Gehrke, L.4    Sonenberg, N.5
  • 20
    • 2442648845 scopus 로고    scopus 로고
    • The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis
    • Ruggero D., Montanaro L., Ma L., et al. The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis. Nat. Med. 2004, 10:484-486.
    • (2004) Nat. Med. , vol.10 , pp. 484-486
    • Ruggero, D.1    Montanaro, L.2    Ma, L.3
  • 21
    • 0025314596 scopus 로고
    • Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap
    • Lazaris-Karatzas A., Montine K.S., Sonenberg N. Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap. Nature 1990, 345:544-547.
    • (1990) Nature , vol.345 , pp. 544-547
    • Lazaris-Karatzas, A.1    Montine, K.S.2    Sonenberg, N.3
  • 22
    • 0033854863 scopus 로고    scopus 로고
    • Translational control of malignancy: the mRNA cap-binding protein, eIF-4E, as a central regulator of tumor formation, growth, invasion and metastasis
    • Zimmer S.G., DeBenedetti A., Graff J.R. Translational control of malignancy: the mRNA cap-binding protein, eIF-4E, as a central regulator of tumor formation, growth, invasion and metastasis. Anticancer Res. 2000, 20:1343-1351.
    • (2000) Anticancer Res. , vol.20 , pp. 1343-1351
    • Zimmer, S.G.1    DeBenedetti, A.2    Graff, J.R.3
  • 23
    • 0028918259 scopus 로고
    • The proto-oncogene/translation factor eIF4E: a survey of its expression in breast carcinomas
    • Kerekatte V., Smiley K., Hu B., Smith A., Gelder F., De Benedetti A. The proto-oncogene/translation factor eIF4E: a survey of its expression in breast carcinomas. Int. J. Cancer 1995, 64:27-31.
    • (1995) Int. J. Cancer , vol.64 , pp. 27-31
    • Kerekatte, V.1    Smiley, K.2    Hu, B.3    Smith, A.4    Gelder, F.5    De Benedetti, A.6
  • 24
    • 0031795848 scopus 로고    scopus 로고
    • Clinical outcome in stage I to III breast carcinoma and eIF4E overexpression
    • 761-763
    • Li B.D., McDonald J.C., Nassar R., De Benedetti A. Clinical outcome in stage I to III breast carcinoma and eIF4E overexpression. Ann. Surg. 1998, 227:756. 761-763.
    • (1998) Ann. Surg. , vol.227 , pp. 756
    • Li, B.D.1    McDonald, J.C.2    Nassar, R.3    De Benedetti, A.4
  • 25
    • 35649001888 scopus 로고    scopus 로고
    • A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer
    • Braunstein S., Karpisheva K., Pola C., et al. A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer. Mol. Cells 2007, 28:501-512.
    • (2007) Mol. Cells , vol.28 , pp. 501-512
    • Braunstein, S.1    Karpisheva, K.2    Pola, C.3
  • 26
    • 33846276209 scopus 로고    scopus 로고
    • 4E-binding protein 1, a cell signaling hallmark in breast cancer that correlates with pathologic grade and prognosis
    • Rojo F., Najera L., Lirola J., et al. 4E-binding protein 1, a cell signaling hallmark in breast cancer that correlates with pathologic grade and prognosis. Clin. Cancer Res. 2007, 13:81-89.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 81-89
    • Rojo, F.1    Najera, L.2    Lirola, J.3
  • 27
    • 0033521868 scopus 로고    scopus 로고
    • Elevated expression of eIF4E in confined early breast cancer lesions: possible role of hypoxia
    • DeFatta R.J., Turbat-Herrera E.A., Li B.D., Anderson W., De Benedetti A. Elevated expression of eIF4E in confined early breast cancer lesions: possible role of hypoxia. Int. J. Cancer 1999, 80:516-522.
    • (1999) Int. J. Cancer , vol.80 , pp. 516-522
    • DeFatta, R.J.1    Turbat-Herrera, E.A.2    Li, B.D.3    Anderson, W.4    De Benedetti, A.5
  • 28
    • 25144470125 scopus 로고    scopus 로고
    • Growth inhibition of head and neck squamous carcinoma cells by small interfering RNAs targeting eIF4E or cyclin D1 alone or combined with cisplatin
    • Oridate N., Kim H.J., Xu X., Lotan R. Growth inhibition of head and neck squamous carcinoma cells by small interfering RNAs targeting eIF4E or cyclin D1 alone or combined with cisplatin. Cancer Biol. Ther. 2005, 4:318-323.
    • (2005) Cancer Biol. Ther. , vol.4 , pp. 318-323
    • Oridate, N.1    Kim, H.J.2    Xu, X.3    Lotan, R.4
  • 29
    • 61349127117 scopus 로고    scopus 로고
    • A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function
    • Melo S.A., Ropero S., Moutinho C., et al. A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat. Genet. 2009, 41:365-370.
    • (2009) Nat. Genet. , vol.41 , pp. 365-370
    • Melo, S.A.1    Ropero, S.2    Moutinho, C.3
  • 30
    • 23644453277 scopus 로고    scopus 로고
    • Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity
    • Moeller B.J., Dreher M.R., Rabbani Z.N., et al. Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity. Cancer Cell 2005, 8:99-110.
    • (2005) Cancer Cell , vol.8 , pp. 99-110
    • Moeller, B.J.1    Dreher, M.R.2    Rabbani, Z.N.3
  • 31
    • 8544229943 scopus 로고    scopus 로고
    • Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1alpha
    • Zhang X., Kon T., Wang H., et al. Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1alpha. Cancer Res. 2004, 64:8139-8142.
    • (2004) Cancer Res. , vol.64 , pp. 8139-8142
    • Zhang, X.1    Kon, T.2    Wang, H.3
  • 32
    • 0030940199 scopus 로고    scopus 로고
    • Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma
    • Li B.D., Liu L., Dawson M., De Benedetti A. Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma. Cancer 1997, 79:2385-2390.
    • (1997) Cancer , vol.79 , pp. 2385-2390
    • Li, B.D.1    Liu, L.2    Dawson, M.3    De Benedetti, A.4
  • 33
    • 34247573392 scopus 로고    scopus 로고
    • Cell-permeable hypoxia-inducible factor-1 (HIF-1) antagonists function as tumor radiosensitizers
    • Shi M., Guo X.T., Shu M.G., Chen F.L., Li L.W. Cell-permeable hypoxia-inducible factor-1 (HIF-1) antagonists function as tumor radiosensitizers. Med. Hypotheses 2007, 69:33-35.
    • (2007) Med. Hypotheses , vol.69 , pp. 33-35
    • Shi, M.1    Guo, X.T.2    Shu, M.G.3    Chen, F.L.4    Li, L.W.5
  • 34
    • 78649738532 scopus 로고    scopus 로고
    • Suppression of hypoxia-inducible factor 1alpha (HIF-1alpha) by tirapazamine is dependent on eIF2alpha phosphorylation rather than the mTORC1/4E-BP1 pathway
    • Zhang J., Cao J., Weng Q., et al. Suppression of hypoxia-inducible factor 1alpha (HIF-1alpha) by tirapazamine is dependent on eIF2alpha phosphorylation rather than the mTORC1/4E-BP1 pathway. PLoS ONE 2010, 5:e13910.
    • (2010) PLoS ONE , vol.5
    • Zhang, J.1    Cao, J.2    Weng, Q.3
  • 35
    • 0038626211 scopus 로고    scopus 로고
    • Tumor response to radiotherapy regulated by endothelial cell apoptosis
    • Garcia-Barros M., Paris F., Cordon-Cardo C., et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 2003, 300:1155-1159.
    • (2003) Science , vol.300 , pp. 1155-1159
    • Garcia-Barros, M.1    Paris, F.2    Cordon-Cardo, C.3
  • 36
    • 2342661143 scopus 로고    scopus 로고
    • Intratumoral hypoxia, radiation resistance, and HIF-1
    • Semenza G.L. Intratumoral hypoxia, radiation resistance, and HIF-1. Cancer Cell 2004, 5:405-406.
    • (2004) Cancer Cell , vol.5 , pp. 405-406
    • Semenza, G.L.1
  • 37
    • 23644445797 scopus 로고    scopus 로고
    • Engaging the vascular component of the tumor response
    • Fuks Z., Kolesnick R. Engaging the vascular component of the tumor response. Cancer Cell 2005, 8:89-91.
    • (2005) Cancer Cell , vol.8 , pp. 89-91
    • Fuks, Z.1    Kolesnick, R.2
  • 38
    • 33745517944 scopus 로고    scopus 로고
    • HIF-1 and tumour radiosensitivity
    • Moeller B.J., Dewhirst M.W. HIF-1 and tumour radiosensitivity. Br. J. Cancer 2006, 95:1-5.
    • (2006) Br. J. Cancer , vol.95 , pp. 1-5
    • Moeller, B.J.1    Dewhirst, M.W.2
  • 39
    • 78651108147 scopus 로고    scopus 로고
    • Enhance tumor radiosensitivity by intracellular delivery of eukaryotic translation initiation factor 4E binding proteins
    • Tian S., Li X.L., Shi M., Yao Y.Q., Li L.W., Xin X.Y. Enhance tumor radiosensitivity by intracellular delivery of eukaryotic translation initiation factor 4E binding proteins. Med. Hypotheses 2011, 76:246-248.
    • (2011) Med. Hypotheses , vol.76 , pp. 246-248
    • Tian, S.1    Li, X.L.2    Shi, M.3    Yao, Y.Q.4    Li, L.W.5    Xin, X.Y.6
  • 40
    • 64149112403 scopus 로고    scopus 로고
    • The Akt/mTOR pathway assures the synthesis of HIF-1alpha protein in a glucose- and reoxygenation-dependent manner in irradiated tumors
    • Harada H., Itasaka S., Kizaka-Kondoh S., et al. The Akt/mTOR pathway assures the synthesis of HIF-1alpha protein in a glucose- and reoxygenation-dependent manner in irradiated tumors. J. Biol. Chem. 2009, 284:5332-5342.
    • (2009) J. Biol. Chem. , vol.284 , pp. 5332-5342
    • Harada, H.1    Itasaka, S.2    Kizaka-Kondoh, S.3


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