Evaluation of the male reproductive toxicity of gallium arsenide

Regulatory Toxicology and Pharmacology

Volumn 64, Issue 1, 2012, Pages 77-86

  Bomhard, Ernst M ^a   Cohen, Samuel M ^b   Gelbke, Heinz Peter ^c   Williams, Gary M ^d  

^a REACh ChemConsult GmbH Dresden   (Germany)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c CinTox Mannheim   (Germany)

^d NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Alveolar proteinosis; Gallium arsenide; Hemolysis; Hypoxemia; Inhalation; Lung inflammation; Mouse; Rat; Semiconductor; Testicular atrophy

Indexed keywords

GALLIUM ARSENIDE; GALLIUM OXIDE; OXIDE; UNCLASSIFIED DRUG;

ADVERSE OUTCOME; ANEMIA; ARTICLE; BIOAVAILABILITY; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; DISEASE ASSOCIATION; DISEASE SEVERITY; EXPERIMENTAL MODEL; EXPERIMENTAL STUDY; HAMSTER; HEMOLYSIS; HISTOPATHOLOGY; HYPOXEMIA; MALE GENITAL SYSTEM; MOLECULAR DYNAMICS; NONHUMAN; OUTCOME ASSESSMENT; PARTICLE SIZE; PNEUMONIA; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; SYNDROME DELINEATION;

ANIMALIA; MUS; RATTUS;

EID: 84863853870     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2012.06.005     Document Type: Article

References (69)

1. Aasebo U., Gyltnes A., Bremnes R.M., Aakvaag A., Slordal L. Reversal of sexual impotence in male patients with chronic obstructive pulmonary disease and hypoxemia with long-term oxygen therapy. J. Steroid Biochem. Mol. Biol. 1993, 46:799-803.
2. Ando A., Ando I., Hiraki T., Hisada K., Nitta K., Ogawa H. Retention and subcellular distribution of 67Ga in normal organs. Nuklearmedizin 1986, 25:45-49.
3. ATSDR. Agency for Toxic Substances and Disease Registry. Toxicological profile for arsenic. August 2007.
4. Battelle Pacific Northwest Laboratories. Thirteen-week subchronic inhalation toxicity study report of gallium oxide in rats. Unpublished Final Report (NIH No. N01-ES-85211), November 1990, cited in NTP 2000.
5. Battelle Pacific Northwest Laboratories. Thirteen-week subchronic inhalation toxicity study report of gallium oxide in mice. Unpublished Final Report (NIH No. N01-ES-85211), December 1990b, cited in NTP 2000.
6. Becker S.M., McCoy K.L. Gallium arsenide selectively up-regulates inflammatory cytokine expression at exposure site. J. Pharmacol. Exp. Ther. 2003, 307:1045-1053.
7. Chinoy N.J., Tewari K., Jhala D.D. Fluoride and/or arsenic toxicity in mice testis with formation of giant cells and subsequent recovery by some antidotes. Fluoride 2004, 37:172-184.
8. Chiou T.J., Chu S.T., Tzeng W.F., Huang Y.C., Liao C.J. Arsenic trioxide impairs spermatogenesis via reducing gene expression levels in testosterone synthesis pathway. Chem. Res. Toxicol. 2008, 21:1562-1569.
9. Chitambar C.R. Medical applications and toxicities of gallium compounds. Int. J. Environ. Res. Public Health 2010, 7:2337-2361.
10. Cho W.S., Duffin R., Thielbeer F., Bradley M., Megson I.L., MacNee W., Poland C.A., Tran C.L., Donaldson K. Zeta potential and solubility to toxic ions as mechanisms of lung inflammation caused by metal/metal oxide nanoparticles. Toxicol. Sci. 2012, 126:469-477.
11. Cikutovic M., Fuentes N., Bustos-Obregón E. Effect of intermittent hypoxia on the reproduction of rats exposed to high altitude in the Chilean Altiplano. Andrologia 1985, 17:178-184.
12. CLH, 2009. Annex XV report, Proposal for harmonised classification and labelling. Substance Name: GALLIUM ARSENIDE, EC Number: 215-114-8, CAS Number: 1303-00-0, Submitted by: France, Date: May 2009, Version: 2.
13. Cohen E.S., Elpern E., Silver M.R. Pulmonary alveolar proteinosis causing severe hypoxemic respiratory failure treated with sequential whole-lung lavage utilizing venovenous extracorporeal membrane oxygenation: a case report and review. Chest 2001, 120:1024-1026.
14. Colomina M.T., Llobet J.M., Sirvent J.J., Domingo J.L., Corbella J. Evaluation of the reproductive toxicity of gallium nitrate in mice. Food Chem. Toxicol. 1993, 31:847-851.
15. Das J., Ghosh J., Manna P., Sinha M., Sil P.C. Taurine protects rat testes against NaAsO(2)-induced oxidative stress and apoptosis via mitochondrial dependent and independent pathways. Toxicol. Lett. 2009, 187:201-210.
16. Donayre J., Guerra-Garcia R., Moncloa F., Sobrevilla L.A. Endocrine studies at high altitude. IV. Changes in the semen of men. J. Reprod. Fertil. 1968, 16:55-58.
17. Dudley H.C., Levine M.D. Studies of the toxic action of gallium. J. Pharmacol. Exp. Ther. 1949, 95:487-493.
18. ECHA. Committee for Risk Assessment. Opinion proposing harmonised classification and labelling at Community level of gallium arsenide. European Chemicals Agency. ECHA/RAC/CLH-0000000792-73-03/F Adopted 25 May 2010.
19. ECHA 2011. Guidance on the Application of Regulation (EC) No. 1272/2008, 323.
20. Engelstad B., Luk S.S., Hattner R.S. Altered 67Ga citrate distribution in patients with multiple red blood cell transfusions. AJR Am. J. Roentgenol. 1982, 139:755-759.
21. Farias J.G., Bustos-Obregon E., Orellana R., Bucarey J.L., Quiroz E., Reyes J.G. Effects of chronic hypobaric hypoxia on testis histology and round spermatid oxidative metabolism. Andrologia 2005, 37:47-52.
22. Farias J.G., Bustos-Obregon E., Reyes J.G. Increase in testicular temperature and vascularization induced by hypobaric hypoxia in rats. J. Androl. 2005, 26:693-697.
23. Farias J.G., Bustos-Obregón E., Tapia P.J., Gutierrez E., Zepeda A., Juantok C., Cruz G., Soto G., Benites J., Reyes J.G. Time course of endocrine changes in the hypophysis-gonad axis induced by hypobaric hypoxia in male rats. J. Reprod. Dev. 2008, 54:18-21.
24. Farias J.G., Puebla M., Acevedo A., Tapia P.J., Guierrez E., Zepeda A., Calaf G., Jauntok C., Reyes J.G. Oxidative stress in rat testis and epididymis under intermittent hypobaric hypoxia: protective role of ascorbate supplementation. J. Androl. 2010, 31:314-321.
25. Fouad A.A., Al-Sultan A.I., Yacoubi M.T. Coenzyme Q10 counteracts testicular injury induced by sodium arsenite in rats. Eur. J. Pharmacol. 2011, 655:91-98.
26. Gasco M., Rubio J., Chung A., Villegas L., Gonzales G.F. Effect of high altitude exposure on spermatogenesis and epididymal sperm count in male rats. Andrologia 2003, 35:368-374.
27. Gosney J.R. Effects of hypobaric hypoxia on the Leydig cell population of the testis of the rat. J. Endocrinol. 1984, 103:59-62.
28. Gosney J.R. Atrophy of Leydig cells in the testes of men with longstanding chronic bronchitis and emphysema. Thorax 1987, 42:615-619.
29. IARC Monographs on the evaluation of carcinogenic risks to humans. Arsenic in drinking water. Vol 84, 2004. IARC, Lyon, France.
30. IARC Monographs on the evaluation of carcinogenic risks to humans. Cobalt in hard metals and cobalt sulfate, gallium arsenide, indium phosphide and vanadium pentoxide. Vol. 86, 2006. IARC, Lyon, France.
31. Ishii S., Shishido F., Miyajima M., Sakuma K., Shigihara T., Kikuchi K. Whole-body gallium-67 scintigraphic findings in IgG4-related disease. Clin. Nucl. Med. 2011, 36:542-545.
32. Jana K., Jana S., Samanta P.K. Effects of chronic exposure to sodium arsenite on hypothalamo-pituitary-testicular activities in adult rats: possible an estrogenic mode of action. Reprod. Biol. Endocrinol. 2006, 4:9-21.
33. Jonkhoff A.R., Plaizier M.A., Ossenkoppele G.J., Teule G.J., Huijgens P.C. High-dose gallium-67 therapy in patients with relapsed acute leukaemia: a feasibility study. Br. J. Cancer 1995, 72:1541-1546.
34. Khan A., Agarwal L. Pulmonary alveolar proteinosis. Respir. Care 2011, 56:1016-1028.
35. Liao W., Cai M., Chen J., Huang J., Liu F., Jiang C., Gao Y. Hypobaric hypoxia causes deleterious effects on spermatogenesis in rats. Reproduction 2010, 139:1031-1038.
36. Mast, T.J., Greenspan, B.J., Dill, J.A., Stoney, K.H., Evanoff, J.J., Rommerein, R.L. Inhalation Developmental Toxicology Studies: Gallium Arsenid in Mice and Rats. Final Report Prepared for the National Institute of Environmental Health Sciences, National Toxicology Program, Contract No. NIH-Y01-ES-70153, December 1990.
37. Meeker J.D., Rossano M.G., Protas B., Diamond M.P., Puscheck E., Daly D., Paneth N., Wirth J.J. Cadmium, lead, and other metals in relation to semen quality: human evidence for molybdenum as a male reproductive toxicant. Environ. Health Perspect. 2008, 116:1473-1479.
38. Meeker J.D., Rossano M.G., Protas B., Padmanahban V., Diamond M.P., Puscheck E., Daly D., Paneth N., Wirth J.J. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum. Fertil. Steril. 2010, 93:130-140.
39. Mehranjani M.S., Hemadi M. The effects of sodium arsenite on the testis structure and sex hormones in vasectomised rats. Iran. J. Reprod. Med. 2007, 5:127-133.
40. Morakinyo A.O., Achema P.U., Adegoke O.A. Effect of zingiber officinale (ginger) on sodium arsenite-induced reproductive toxicity in male rats. Afr. J. Biomed. Res. 2010, 13:39-45.
41. Mukherjee S., Mukhopadhyay P. Studies on arsenic toxicty in male rat gonads and its protection by high dietary protein supplementation. Al. Ameen J. Med. Sci. 2009, 2:73-77.
42. NTP Report on the Toxicity Studies of Cobalt Sulfate Heptahydrate in F344/N Rats and B6C3F1 Mice (Inhalation studies), NTP TOX 5, 1991.
43. NTP Technical Report on the Toxicology and Carcinogenesis Studies of Talc in F344/N Rats and B6C3F1 Mice (Inhalation Studies), NTP TR 421, 1993.
44. NTP Report on the Toxicity Studies of Cadmium Oxide Administered by Inhalation to F344/N Rats and B6C3F1 Mice (Inhalation studies), NTP TOX 38, 1995.
45. NTP Technical Report on the Toxicology and Carcinogenesis of Nickel Oxide in F344/N Rats and B6C3F1 Mice (Inhalation studies), NTP TR 451, 1996a.
46. NTP Technical Report on the Toxicology and Carcinogenesis of Nickel Subsulfide in F344/N Rats and B6C3F1 Mice (Inhalation studies), NTP TR 453, 1996b.
47. NTP Technical Report on the Toxicology and Carcinogenesis of Nickel Sulfate Heptahydrate in F344/N Rats and B6C3F1 Mice (Inhalation studies), NTP TR 454, 1996c.
48. NTP Technical Report on the Toxicology and Carcinogenesis of Molybdenum Trioxide in F344/N Rats and B6C3F1 Mice (Inhalation studies), NTP TR 462, 1997.
49. NTP Technical Report on the Toxicology and Carcinogenesis of Cobalt Sulfate Heptahydrate in F344/N Rats and B6C3F1 Mice (Inhalation Studies), NTP TR 471, 1998.
50. NTP Technical Report on the Toxicology and Carcinogenesis of Gallium Arsenide in F344/N Rats and B6C3F1 Mice (Inhalation studies), NTP TR 492, 2000.
51. NTP Technical Report on the Toxicology and Carcinogenesis of Indium Phospide in F344/N Rats and B6C3F1 Mice (Inhalation studies), NTP TR 499, 2001.
52. NTP Technical Report on the Toxicology and Carcinogenesis of Vanadium Pentoxide in F344/N Rats and B6C3F1 Mice (Inhalation studies), NTP TR 507, 2002.
53. Ohyama M.D., Ishinishi N., Hisanaga A., Yamamoto A. Comparative chronic toxicity, including tumorigenicity, of gallium arsenide and arsenic trioxide intratracheally instilled into hamsters. Appl. Organomet. Chem. 1988, 2:333-337.
54. Omura M., Tanaka A., Zhao M., Hirata M., Makita Y., Inoue N., Gotoh K. Toxic effects of gallium arsenide on sperm in rats by repeated intratracheal instillations. Sangyo Eiseigaku Zasshi (J. Occup. Health) 1995, 37:165-166.
55. Omura M., Tanaka A., Hirata M., Zhao M., Makita Y., Inoue N., Gotoh K., Ishinishi N. Testicular toxicity of gallium arsenide, indium arsenide, and arsenic oxide in rats by repetitive intratracheal instillation. Fundam. Appl. Toxicol. 1996, 32:72-78.
56. Omura M., Hirata M., Tanaka A., Zhao M., Makita Y., Inoue N., Gotoh K., Ishinishi N. Testicular toxicity evaluation of arsenic-containing binary compound semiconductors, gallium arsenide and indium arsenide, in hamsters. Toxicol. Lett. 1996, 16:123-129.
57. Ozaki K., Haseman J.K., Hailey J.R., Maronpot R.R., Nyska A. Association of adrenal pheochromocytoma and lung pathology in inhalation studies with particulate compounds in the male F344 rat-the National Toxicology Program experience. Toxicol. Pathol. 2002, 30:263-270.
58. Semple P.D., Beastall G.H., Brown T.M., Stirling K.W., Mills R.J., Watson W.S. Sex hormone suppression and sexual impotence in hypoxic pulmonary fibrosis. Thorax 1984, 39:46-51.
59. Seymour J.F., Presneill J.J. Pulmonary alveolar proteinosis. Progress in the first 44 years. Am. J. Respir. Crit. Care Med. 2002, 166:215-235.
60. Shevantaeva O.N., Kosyuga Y.I. Effect of acute hypobaric hypoxia on spermatogenesis and lactate concentration in testicular tissue of male albino rats. Bull. Exp. Biol. Med. 2006, 141:20-22.
61. Tanaka A., Hirata M., Omura M., Zhao M., Makita Y., Yamazaki K., Inoue N., Gotoh K. Comparative study of the toxic effects of gallium arsenide, indium arsenide and arsenic trioxide following intratracheal instillations to the lung of Syrian golden hamsters. Fukuoka Acta Med. 2000, 91:21-33.
62. Verratti V., Berardinelli F., Di Giulio C., Bosco G., Cacchio M., Pellicciotta M., Nicolai M., Martinotti S., Tenaglia R. Evidence that chronic hypoxia causes reversible impairment on male fertility. Asian J. Androl. 2008, 10:602-606.
63. Webb D.R., Sipes I.G., Carter D.E. In vitro solubility and in vivo toxicity of gallium arsenide. Toxicol. Appl. Pharmacol. 1984, 76:96-104.
64. Webb D.R., Wilson S.E., Carter D.E. Comparative pulmonary toxicity of gallium arsenide, gallium(III) oxide, or arsenic(III) oxide intratracheally instilled into rats. Toxicol. Appl. Pharmacol. 1986, 82:405-416.
65. Webb D.R., Wilson S.E., Carter D.E. Pulmonary clearance and toxicity of respirable gallium arsenide particulates intratracheally instilled into rats. Am. Ind. Hyg. Assoc. J. 1987, 48:660-667.
66. Whaley S.R., English D.S., Hu E.L., Barbara P.F., Belcher A.M. Selection of peptides with semi-conductor binding specificity for directed nanocrystal assembly. Nature 2000, 405:665-668.
67. Wolff R.K., Henderson R.F., Eidson A.F., Pickrell J.A., Rothenberb S.J., Hahn F.F. Toxicity of gallium oxide particles following a 4-week inhalation exposure. J. Appl. Toxicol. 1988, 8:191-199.
68. Yamauchi H., Takahashi K., Mashiko M., Yamamura Y. Biological monitoring of arsenic exposure of GaAs- and inorganic arsenic-exposed workers by determination of inorganic arsenic and its metabolites in urine and hair. Am. Ind. Hyg. Assoc. J. 1989, 50:606-612.
69. Yokohira M., Kuno T., Yamakawa K., Hosokawa K., Matsuda Y., Hashimoto N., Suzuki S., Saoo K., Imaida K. Lung toxicity of 16 fine particles on intratracheal instillation in a bioassay model using F344 male rats. Toxicol. Pathol. 2008, 36:620-631.