Fluoride and/or arsenic toxicity in mice testis with formation of giant cells and subsequent recovery by some antidotes

Fluoride

Volumn 37, Issue 3, 2004, Pages 172-184

  Chinoy, N J ^a,b   Tewari, K ^a   Jhala, D D ^a  

^a Gujarat University ^*

^b GUJARAT UNIVERSITY   (India)

Author keywords

Arsenic and testis; Fluoride and testis; Spermatogenesis; Testicular steroidogenesis; Testis structure alterations; Toxicity reversal

Indexed keywords

3BETA HYDROXY DELTA5 STEROID DEHYDROGENASE; ALPHA TOCOPHEROL; ANTIDOTE; ARSENIC; ARSENIC TRIOXIDE; ASCORBIC ACID; CALCIUM PHOSPHATE; CHOLESTEROL; FLUORIDE; FLUORIDE SODIUM; HYDROXYSTEROID DEHYDROGENASE; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARSENIC POISONING; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FLUOROSIS; GIANT CELL; HISTOPATHOLOGY; HORMONE ACTION; MALE; MOUSE; NONHUMAN; SPERMATOGENESIS; STEROIDOGENESIS; TESTIS; TESTOSTERONE BLOOD LEVEL; TREATMENT OUTCOME; VITAMIN SUPPLEMENTATION;

ANIMALIA;

EID: 9144247734     PISSN: 00154725     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. World Health Organisation. Environmental Health Criteria 18: Arsenic. Geneva: WHO International Programme on Chemical Safety; 1981.
2. World Health Organisation. Environmental Health Criteria. 36: Fluorine and fluorides. Geneva,: WHO International Programme on Chemical Safety, United Nations Environment Programme, the International Labour Organization, and the World Health Organization; 1984. p. 1-136.
3. Chinoy NJ. Studies on fluoride, aluminium and arsenic toxicity in mammals and amelioration by some antidotes. In: Tripathi G. editor. Modern Trends in Environmental Biology. New Delhi: CBS Publishers; 2002. p. 164-93.
4. Chinoy NJ, Sharma AK. Amelioration of fluoride toxicity by vitamins E and D in reproductive functions of male mice. Fluoride 1998;31(4):203-16.
5. Chinoy NJ, Mehta D. Beneficial effects of the amino acids glycine and glutamine on testis of mice treated with sodium fluoride. Fluoride 1999;32(3):162-70.
6. Sprando RL, Black TN, Ames MJ, Rorie JI, Collins TF. Effect of intratesticular injection of sodium fluoride on spermatogenesis. Food Chem Toxicol 1996;34(4):377-84.
7. Sprando RL, Collins TF, Black TN, Rorie J, Ames MJ, O'Donnell M. Testing the potential of sodium fluoride to affect spermatogenesis in the rat. Food Chem Toxicol 1997;35(9):881-90.
8. Collins TF, Sprando RL, Black TN, Shackelford ME, Bryant MA, Olejnik N, et al. Multigenerational evaluation of sodium fluoride in rats. Food Chem Toxicol 2001;39(6):601-13.
9. Elbetieha A, Darmani H, Al-Hiyasat AS. Fertility effects of sodium fluoride in male mice. Fluoride 2000;33(3):128-34.
10. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-75.
11. Zlatkis A, Zak B, Boyle AJ. A new method for the direct determination of serum cholesterol. J Lab Clin Med 1953;41:486-92.
12. Talalay P. Hydroxysteroid dehydrogenases. In: Colowick SP, Kaplan NO, editors. Methods in enzymology. Vol. V. New York: Academic Press Inc; 1962. p. 512-6.
13. Peterson MA, Swerdlofif RS. Separation of bound from free hormone in radioimmunoassay of lutropin and follitropin. Clin Chem 1979;25:1239-41.
14. Akbarsha MA, Sivasamy P. Apoptosis in male germinal line cells of rat in vivo: caused by phosphamidon. Cytobios 1997;91:33-44.
15. Kour K, Singh J. Histological findings of mice testes following fluoride ingestion. Fluoride 1980;13(4):160-2.
16. Chinoy NJ, Sequeira E. Effects of fluoride on the histoarchitecture of reproductive organs of the male mouse. Reprod Toxicol 1989;3(4):261-7.
17. Susheela AK, Kumar A. A study of the effect of high concentrations of fluoride on the reproductive organs of male rabbits, using light and scanning electron microscopy. J Reprod Fert 1991;92:353-60.
18. Kumar A, Susheela AK. Ultrastructural studies of spermiogenesis in rabbit exposed to chronic fluoride toxicity. Int J Fert Menopausal Stud 1994;39(3):164-71.
19. Bhatnagar M, Susheela AK, Soundaram CC, Thakkar D, Roy KK, Kriplani A. Effect of fluoride contamination of drinking water on human spermatozoa [abstract]. Fluoride 2001;34(3):196.
20. Zakrzewska H, Udala J, Blaszczyk B. In vitro influence of sodium fluoride on ram semen quality and enzyme activities. Fluoride 2002;35(3):153-60.
21. Shukla JP, Pandey K. Impaired spermatogenesis in arsenic treated fresh water fish, Colisa fasciatus (B1 & Sch). Toxicol Lett 1984;21:191-5.
22. Chinoy NJ, Sequeira E. Fluoride induced biochemical changes in reproductive organs of male mice. Fluoride 1989;22(2):78-85.
23. Chinoy NJ, Mehta D. Effects of protein supplementation and deficiency on fluori de-induced toxicity in reproductive organs in male mice. Fluoride 1999;32(4):204-14.
24. Chinoy NJ, Tewari K. Beneficial effects of some vitamins and calcium in overcoming fluoride/ arsenic induced toxicity in epididymis of mice [abstract]. XXII Conference of Society of Reproductive Biology and Comparative Endocrinology, University of Madras, Chennai, January 25-27, 2004.
25. Bano R, Sahdev S, Lall SB. Biochemical changes in the testis of Swiss albino mice exposed to chronic ingestion of sodium fluoride. Indian J Environ Toxicol 1996;6(1):19-21.
26. Chinoy NJ, Narayana MV, Dalal V, Rawat M, Patel D. Amelioration of fluoride toxicity in some accessory reproductive glands and spermatozoa of rat. Fluoride 1995;28(2):75-86.
27. Chinoy NJ, Shukla S, Walimbe AS, Bhattacharya S. Fluoride toxicity on rat testis and cauda epididymal tissue components and its reversal. Fluoride 1997;30(1):41-50.
28. Aposhian HV. Enzymatic methylation of arsenic species and other new approaches to arsenic toxicity. Ann Rev Pharmacol Toxicol 1997;37:397-419.
29. Narayana MV, Chinoy NJ. Effect of fluoride on rat testicular steroidogenesis. Fluoride 1994;27(1):7-12.
30. Zhao ZL, Wu NP, Gao WH. The influence of fluoride on the content of testosterone and cholesterol in rat. Fluoride 1995;28(3):128-30.
31. Sarkar M, Chaudhuri GR, Chattopadhyay A, Biswas NM. Effect of sodium arsenite on spermatogenesis, plasma gonadotrophins and testosterone in rats. Asian J Androl 2003;5(1):27-31.
32. Susheela AK, Jethanandani P. Circulating testosterone levels in skeletal fluorosis patients. J Toxicol Clin Toxicol 1996;34(2):183-9.
33. Ghosh D, Das Sarkar S, Maiti R, Jana D, Das UB. Testicular toxicity in sodium fluoride treated rats: association with oxidative stress. Reprod Toxicol 2002;16(4):385-90.
34. 5 3β and 17β hydroxysteroid dehydrogenase activities in albino rats: dose and duration dependent response. Med Sci Res 1991;19:789-90.
35. Pant N, Kumar R, Murthy RC, Srivastava SP. Male reproductive effect of arsenic in mice. Biometals 2001;14:113-7.
36. Patel D, Chinoy NJ. Synergistic action of ascorbic acid and calcium in mitigation of fluoride induced toxicity in uterus of mice. Indian J Environ Toxicol 1997;7(1):16-9.