Arsenic trioxide impairs spermatogenesis via reducing gene expression levels in testosterone synthesis pathway

Chemical Research in Toxicology

Volumn 21, Issue 8, 2008, Pages 1562-1569

  Chiou, Tzeon Jye ^a   Chu, Sin Tak ^b   Tzeng, Woan Fang ^c   Huang, Yu Chen ^a   Liao Jr , Chi ^c  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^c FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC TRIOXIDE; MESSENGER RNA; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDIDYMIS; FOOD INTAKE; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIVER; MALE; MOUSE; NONHUMAN; SEMEN ANALYSIS; SEMINIFEROUS TUBULE; SPERMATOGENESIS; SPERMATOZOON MOTILITY; TESTIS; TESTOSTERONE SYNTHESIS;

ANIMALS; ANIMALS, OUTBRED STRAINS; ARSENICALS; CELL SURVIVAL; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; GENE EXPRESSION REGULATION; GROWTH INHIBITORS; INJECTIONS, SUBCUTANEOUS; LEYDIG CELLS; LUTEINIZING HORMONE; MALE; MICE; MICE, INBRED ICR; OXIDES; RNA, MESSENGER; SEMINIFEROUS TUBULES; SPERM MOTILITY; SPERMATOGENESIS; SPERMATOZOA; TESTIS; TESTOSTERONE;

MUS;

EID: 51449084639     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx700366x     Document Type: Article

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