Cytotoxicity induced by deltamethrin and its metabolites in SH-SY5Y cells can be differentially prevented by selected antioxidants

Toxicology in Vitro

Volumn 26, Issue 6, 2012, Pages 823-830

  Romero, Alejandro ^a   Ramos, Eva ^a   Castellano, Víctor ^a   Martínez, María Aranzazu ^a   Ares, Irma ^a   Martínez, Marta ^a   Martínez Larrañaga, María Rosa ^a   Anadón, Arturo ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Antioxidants; Cytotoxicity; Deltamethrin; Metabolites; SH SY5Y cells

Indexed keywords

2' HYDROXYDELTAMETHRIN; 3 PHENOXYBENZOIC ACID; 4' HYDROXYDELTAMETHRIN; ACETYLCYSTEINE; DELTAMETHRIN; DELTAMETHRIN DERIVATIVE; LIPID PEROXIDE; MALONALDEHYDE; MELATONIN; NITRIC OXIDE; TROLOX C; UNCLASSIFIED DRUG;

ARTICLE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; METABOLITE; NEUROTOXICITY; OXIDATIVE STRESS;

ACETYLCYSTEINE; ANTIOXIDANTS; BENZOATES; CELL LINE, TUMOR; CELL SURVIVAL; CHROMANS; HUMANS; INSECTICIDES; LIPID PEROXIDATION; MELATONIN; NEUTRAL RED; NITRILES; NITRITES; PYRETHRINS;

EID: 84863836887     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.05.004     Document Type: Article

References (50)

1. Anadón A., Martínez-Larrañaga M.R., Diaz M.J., Bringas P. Toxicokinetics of permethrin in the rat. Toxicology and Applied Pharmacology 1991, 110(1):1-8.
2. Anadon A., Martinez-Larranaga M.R., Fernandez-Cruz M.L., Diaz M.J., Fernandez M.C., Martinez M.A. Toxicokinetics of deltamethrin and its 4'-HO-metabolite in the rat. Toxicology and Applied Pharmacology 1996, 141:8-16.
3. Anadón A., Martínez M., Martínez M.A., Diaz M.J., Martínez-Larrañaga M.R. Toxicokinetics of lambda-cyhalothrin in rats. Toxicology Letters 2006, 165:47-56.
4. Anand S.S., Bruckner J.V., Haines W.T., Muralidhara S., Fisher J.W., Padilla S. Characterization of deltamethrin metabolism by rat plasma and liver microsomes. Toxicology and Applied Pharmacology 2006, 212:156-166.
5. Banerjee B.D., Seth V., Ahmed R.S. Pesticide-induced oxidative stress: perspectives and trends. Reviews on Environmental Health 2001, 16:1-40.
6. Bauche F., Stephan J.P., Touzalin A.M., Jegou B. In vitro regulation of an inducible-type NO synthase in the rat seminiferous tubule cells. Biology of Reproduction 1998, 58:431-438.
7. Bonneh-Barkay D., Langston W.J., Di Monte D.A. Toxicity of redox cycling pesticides in primary mesencephalic cultures. Antioxidants and Redox Signaling 2005, 7:649-653.
8. Borenfreund E., Puerner J.A. A simple quantitative procedure using monolayer cultures for cytotoxicity assays (HTD/NR90). Journal of Tissue Culture Methods 1984, 9:7-9.
9. Bradberry S.M., Cage S.A., Proudfoot A.T., Vale J.A. Poisoning due to pyrethroids. Toxicological Reviews 2005, 24:93-106.
10. Braguini W.L., Cadena S.M.S.C., Carnieri E.G.S., Rocha M.E.M., De Oliveira E.G.S. Effects of deltamethrin on functions of rat liver mitochondria and on native and synthetic model membranes. Toxicology Letters 2004, 152:191-202.
11. Cort W.M., Scott J.W., Araujo M., Mergens W.J., Cannalonga M.A., Osadca M., Harley H., Parrish D.R., Pool W.R. Antioxidant activity and stability of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid. Journal of the American Oil Chemists' Society 1975, 52:174-178.
12. Das R., Steege A., Baron S., Beckman J., Harrison R. Pesticide-related illness among migrant farm workers in the United States. International Journal of Occupational and Environmental Health 2001, 7:303-312.
13. Dayal M., Parmar D., Dhawan A., Ali M., Dwivedi U.N., Doehmer J., Seth P.K. Induction of rat brain and liver cytochrome P450 1A1/1A2 and 2B1/2B2 isoenzymesn by deltamethrin. Environmental Toxicology and Pharmacology 1999, 7:169-178.
14. Dayal M., Parmar D., Dhawan A., Ali M., Dwivedi U.N., Seth P.K. Effect of pretreatment of cytochrome P450 (P450) modifiers on neurobehavioral toxicity induced by deltamethrin. Food and Chemical Toxicology 2003, 41:431-437.
15. Denizot F., Lang R. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. Journal of Immunological Methods 1986, 89:271-277.
16. Dinis-Oliveira R.J., Remiao F., Carmo H., Duarte J.A., Navarro A.S., Bastos M.L., Carvalho F. Paraquat exposure as an etiological factor of Parkinson's disease. Neurotoxicology 2006, 27:1110-1122.
17. El-Demerdash F.M., Yousef M.I., Al-Salhen K.S. Protective effects of isoflavone on some biochemical parameters affected by cypermethrin in male rabbits. Journal of Environmental Science and Health 2003, B38:365-378.
18. El-Demerdash F.M. Lambda-cyhalothrin-induced changes in oxidative stress biomarkers in rabbit erythrocytes and alleviation effect of some antioxidants. Toxicology in Vitro 2007, 21:392-397.
19. El-Gohary M., Awara W.M., Nassar S., Hawas S. Deltamethrin-induced testicular apoptosis in rats: the protective effect of nitric oxide synthase inhibitor. Toxicology 1999, 132:1-8.
20. Elliott M., Farnham A.W., Janes N.F., Needham P.H., Pulman D.A. Synthetic insecticide with a new order of activity. Nature 1974, 248:710-711.
21. Gaughan L.C., Unai T., Casida J.E. Permethrin metabolism in rats. Journal of Agricultural and Food Chemistry 1976, 25:9-17.
22. Giray B., Gurbay A., Hincal F. Cypermethrin-induced oxidative stress in rat brain and liver is prevented by vitamin E or allopurinol. Toxicology Letters 2001, 118:139-146.
23. Godin S.J., DeVito M.J., Hughes M.F., Ross D.G., Scollon E.J., Starr J.M., Setzer R.W., Conolly R.B., Tornero-Velez R. Physiologically based pharmacokinetic modeling of deltamethrin: development of a rat and human diffusion-limited model. Toxicological Sciences 2010, 115:330-343.
24. Gray A.J., Rickard J. Toxicity of pirethroids to rats after direct injection into the central nervous system. Neurotoxicology 1982, 3:25-35.
25. Grosse G., Thiele T., Heuckendorf E., Schopp E., Merder S., Pickert G., Ahnert-Hilger G. Deltamethrin differentially affects neuronal subtypes in hippocampal primary culture. Neuroscience 2002, 112:233-241.
26. Kaneko H., Miyamoto J. Pyrethroid chemistry and metabolism. Handbook of Pesticide Toxicology 2001, 1263-1288. Academic Press, San Diego. R. Krieger (Ed.).
27. Lawrence L.J., Casida J.E. Stereospecific action of pyrethroid insecticides on the gamma-aminobutyric acid receptor-ionophore complex. Science 1983, 221:1399-1401.
28. Li H.Y., Wu S.Y., Ma Q., Shi N. The pesticide deltamethrin increases free radical production and promotes nuclear translocation of the stress response transcription factor Nrf2 in rat brain. Toxicology and Industrial Health 2011, 27:579-590.
29. Li H.Y., Wu S.Y., Shi N. Transcription factor Nrf2 activation by deltamethrin in PC12 cells: involvement of ROS. Toxicology Letters 2007, 171:87-98.
30. Mcmillan C.R., Sharma R., Ottenhof T., Niles N.P. Modulation of tyrosine hydroxylase expression by melatonin in human SH-SY5Y neuroblastoma cells. Neuroscience Letters 2007, 419:202-206.
31. Meacham C.A., Freudenrich T.M., Anderson W.L., Sui L., Lyons-Darden T., Barone D., Gilbert M.E., Mundy W.R., Shafer T.J. Accumulation of methylmercury or polychlorinated biphenyls in vitro models of rat neuronal tissue. Toxicology and Applied Pharmacology 2005, 205:177-187.
32. Munday W.R., Freudenrich T.M., Crofton K.M., DeVito M.J. Accumulation of PBDE-47 in primary cultures of rat neocortical cells. Toxicological Sciences 2004, 82:164-169.
33. Pandi-Perumal S.R., Srinivasan V., Maestroni G.J.M., Cardinali D.P., Poeggeler B., Hardeland R. Melatonin: nature's most versatile biological signal?. FEBS Journal 2006, 273:2813-2838.
34. Pham H.C., Navarro-Delmasure C., Clavel P., van Haverbeke G., Cheav S.L. Toxicological studies of deltamethrin. International Journal of Tissue Reactions 1984, 6:127-133.
35. Rickard J., Brodie M.E. Correlation of blood and brain levels of the neurotoxic pyrethroid deltamethrin with the onset of symptoms in rats. Pesticide Biochemistry and Physiology 1985, 23:143-156.
36. Rios J.C., Repetto G., Jos A., del Peso A., Salguero M., Camean A., Repetto M. Tribromophenol induces the differentiation of SH-SY5Y human neuroblastoma cells in vitro. Toxicology in Vitro 2003, 17:635-641.
37. Rodriguez C., Mayo J.C., Sainz R.M., Antolin I., Herrera F., Martin V., Reiter R.J. Regulation of antioxidant enzymes: a significant role for melatonin. Journal of Pineal Research 2004, 36:1-9.
38. Romero A., Egea J., Garcia A.G., Lopez M.G. Synergistic neuroprotective effect of combined low concentrations of galantamine and melatonin against oxidative stress in SH-SY5Y neuroblastoma cells. Journal of Pineal Research 2010, 49:141-148.
39. Ruzo L.O., Casida J.E. Metabolism and toxicology of pyrethroids with dihalovinyl substituents. Environmental Health Perspectives 1977, 21:285-292.
40. Ruzo L.O., Unai T., Casida J.E. Decamethrin metabolism in rats. Journal of Agricultural and Food Chemistry 1978, 26:918-925.
41. Ruzo L.O., Engel J.L., Casida J.E. Decamethrin metabolites from oxidative, hydrolytic, and conjugative reactions in mice. Journal of Agricultural and Food Chemistry 1979, 27:725-731.
42. Sadowska-Woda I., Wojcik N., Karowicz-Bilinska A., Bieszczad-Bedrejczuk E. Effect of selected antioxidants in beta-cyfluthrin-induced oxidative stress in human erythrocytes in vitro. Toxicology in Vitro 2010, 24:879-884.
43. Shafer T.J., Hughes M.F. Accumulation of pyrethroid compounds in primary cultures from rat cortex. Toxicology in Vitro 2010, 24:2053-2057.
44. Shafer T.J., Meyer D.A., Crofton K.M. Developmental neurotoxicity of pyrethroid insecticides: critical review and future research needs. Environmental Health Perspectives 2005, 113:123-136.
45. Skandrani D., Gaubin Y., Beau B., Murat J.C., Vincent C., Croute F. Effect of selected insecticides on growth rate and stress protein expression in cultured human A549 and SH-SY5Y cells. Toxicology in Vitro 2006, 20:1378-1386.
46. Soderlund D.M., Casida J.E. Effects of pyrethroid structure on rates of hydrolisis and oxidadion by mouse liver microsomal enzymes. Pesticide Biochemistry and Physiology 1977, 17(7):391-401.
47. Trushina E., McMurray C.T. Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases. Neuroscience 2007, 145:1233-1248.
48. Vais H., Williamson M.S., Devonshire A.L., Usherwood P.N. The molecular interactions of pyrethroid insecticides with insect and mammalian sodium channels. Pest Management Science 2001, 57:877-888.
49. Wu A., Li L., Liu Y. Deltamethrin induces apoptotic cell death in cultured cerebral cortical neurons. Toxicology and Applied Pharmacology 2003, 187:50-57.
50. Yousef M.I., Awad T.I., Mohamed E.H. Deltamethrin-induced oxidative damage and biochemical alterations in rat and its attenuation by Vitamin E. Toxicology 2006, 227:240-247.