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Volumn 51, Issue 7, 2012, Pages 1170-1180

Role of p21-activated kinase 1 in regulating the migration and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients

Author keywords

Fibroblast like synoviocytes; Invasion; Migration; P21 activated kinase 1; Rheumatoid arthritis

Indexed keywords

COLLAGENASE 3; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE 14; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; P21 ACTIVATED KINASE 1; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84863828199     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/kes031     Document Type: Article
Times cited : (25)

References (37)
  • 1
    • 0035932519 scopus 로고    scopus 로고
    • Cytokine pathways and joint inflammation in rheumatoid arthritis
    • Choy EH, Panayi GS. Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med 2001; 344:907-16.
    • (2001) N Engl J Med , vol.344 , pp. 907-916
    • Choy, E.H.1    Panayi, G.S.2
  • 2
    • 33745612984 scopus 로고    scopus 로고
    • Synovial fibroblasts: key players in rheumatoid arthritis
    • Huber LC, Distler O, Tarner I et al. Synovial fibroblasts: key players in rheumatoid arthritis. Rheumatology 2006;45: 669-75.
    • (2006) Rheumatology , vol.45 , pp. 669-675
    • Huber, L.C.1    Distler, O.2    Tarner, I.3
  • 4
    • 0030808458 scopus 로고    scopus 로고
    • H-ras oncogene point mutation in arthritic synovium
    • Roivainen A, Jalava J, Pirila L et al. H-ras oncogene point mutation in arthritic synovium. Arthritis Rheum 1997;40: 1636-43.
    • (1997) Arthritis Rheum , vol.40 , pp. 1636-1643
    • Roivainen, A.1    Jalava, J.2    Pirila, L.3
  • 5
    • 33749023888 scopus 로고    scopus 로고
    • Mechanisms of disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis
    • Müller-Ladner U, Pap T, Gay RE, Neidhart M, Gay S. Mechanisms of disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis. Nat Clin Pract Rheumatol 2005;1:102-10.
    • (2005) Nat Clin Pract Rheumatol , vol.1 , pp. 102-110
    • Müller-Ladner, U.1    Pap, T.2    Gay, R.E.3    Neidhart, M.4    Gay, S.5
  • 6
    • 0029855587 scopus 로고    scopus 로고
    • Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice
    • Müller-Ladner U, Kriegsmann J, Franklin BN et al. Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice. Am J Pathol 1996;149:1607-15.
    • (1996) Am J Pathol , vol.149 , pp. 1607-1615
    • Müller-Ladner, U.1    Kriegsmann, J.2    Franklin, B.N.3
  • 7
    • 27444446925 scopus 로고    scopus 로고
    • Are fibroblasts involved in joint destruction?
    • Pap T, Meinecke I, Muller-Ladner U, Gay S. Are fibroblasts involved in joint destruction? Ann Rheum Dis 2005; 64(Suppl. 4):iv52-4.
    • (2005) Ann Rheum Dis , vol.64 , Issue.SUPPL. 4
    • Pap, T.1    Meinecke, I.2    Muller-Ladner, U.3    Gay, S.4
  • 8
    • 71549117557 scopus 로고    scopus 로고
    • Synovial fibroblasts spread rheumatoid arthritis to unaffected joints
    • Lefèvre S, Knedlal A, Tenniel C et al. Synovial fibroblasts spread rheumatoid arthritis to unaffected joints. Nat Med 2009;15:1414-20.
    • (2009) Nat Med , vol.15 , pp. 1414-1420
    • Lefèvre, S.1    Knedlal, A.2    Tenniel, C.3
  • 9
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by Cdc42 and Rac1
    • Manser E, Leung T, Salihuddin H, Zhao ZS, Lim L. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 1994;367:40-6.
    • (1994) Nature , vol.367 , pp. 40-46
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.S.4    Lim, L.5
  • 11
    • 0038554077 scopus 로고    scopus 로고
    • Biology of the p21-activated kinases
    • Bokoch GM. Biology of the p21-activated kinases. Annu Rev Biochem 2003;72:743-81.
    • (2003) Annu Rev Biochem , vol.72 , pp. 743-781
    • Bokoch, G.M.1
  • 12
    • 0031036626 scopus 로고    scopus 로고
    • Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes
    • Manser E, Huang HY, Loo TH et al. Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes. Mol Cell Biol 1997;17:1129-43.
    • (1997) Mol Cell Biol , vol.17 , pp. 1129-1143
    • Manser, E.1    Huang, H.Y.2    Loo, T.H.3
  • 13
    • 0029056399 scopus 로고
    • A novel serine kinase activated by Rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20
    • Martin GA, Bollag G, McCormick F, Abo A. A novel serine kinase activated by Rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20. EMBO J 1995;14:1970-8.
    • (1995) EMBO J , vol.14 , pp. 1970-1978
    • Martin, G.A.1    Bollag, G.2    McCormick, F.3    Abo, A.4
  • 15
    • 33846818859 scopus 로고    scopus 로고
    • Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs
    • Eswaran J, Lee WH, Debreczeni JE et al. Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs. Structure 2007;15:201-13.
    • (2007) Structure , vol.15 , pp. 201-213
    • Eswaran, J.1    Lee, W.H.2    Debreczeni, J.E.3
  • 17
    • 34447517646 scopus 로고    scopus 로고
    • Specificity profiling of Pak kinases allows identification of novel phosphorylation sites
    • Rennefahrt UE, Deacon SW, Parker SA et al. Specificity profiling of Pak kinases allows identification of novel phosphorylation sites. J Biol Chem 2007;282:15667-78.
    • (2007) J Biol Chem , vol.282 , pp. 15667-15678
    • Rennefahrt, U.E.1    Deacon, S.W.2    Parker, S.A.3
  • 19
    • 0242664130 scopus 로고    scopus 로고
    • Akt phosphorylation of serine 21 on Pak1 modulates Nck binding and cell migration
    • Zhou GL, Zhuo Y, King CC et al. Akt phosphorylation of serine 21 on Pak1 modulates Nck binding and cell migration. Mol Cell Biol 2003;23:8058-69.
    • (2003) Mol Cell Biol , vol.23 , pp. 8058-8069
    • Zhou, G.L.1    Zhuo, Y.2    King, C.C.3
  • 20
    • 0029950672 scopus 로고    scopus 로고
    • Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members
    • Frost JA, Xu S, Hutchison MR, Marcus S, Cobb MH. Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members. Mol Cel Biol 1996;16:3707-13.
    • (1996) Mol Cel Biol , vol.16 , pp. 3707-3713
    • Frost, J.A.1    Xu, S.2    Hutchison, M.R.3    Marcus, S.4    Cobb, M.H.5
  • 21
    • 0030134625 scopus 로고    scopus 로고
    • Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
    • Brown JL, Stowers L, Baer M et al. Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway. Curr Biol 1996;6:598-605.
    • (1996) Curr Biol , vol.6 , pp. 598-605
    • Brown, J.L.1    Stowers, L.2    Baer, M.3
  • 22
    • 0034697303 scopus 로고    scopus 로고
    • Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1
    • Adam L, Vadlamudi R, Mandal M, Chernoff J, Kumar R. Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1. J Biol Chem 2000;275:12041-50.
    • (2000) J Biol Chem , vol.275 , pp. 12041-12050
    • Adam, L.1    Vadlamudi, R.2    Mandal, M.3    Chernoff, J.4    Kumar, R.5
  • 23
    • 77954951627 scopus 로고    scopus 로고
    • p21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-pathways
    • Huynh N, Liu KH, Baldwin GS, He H. p21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-pathways. Biochim Biophys Acta 2010;180:1106-13.
    • (2010) Biochim Biophys Acta , vol.180 , pp. 1106-1113
    • Huynh, N.1    Liu, K.H.2    Baldwin, G.S.3    He, H.4
  • 24
    • 34248531653 scopus 로고    scopus 로고
    • p21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation
    • Ching YP, Leong VY, Lee MF et al. p21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation. Cancer Res 2007;67:3601-8.
    • (2007) Cancer Res , vol.67 , pp. 3601-3608
    • Ching, Y.P.1    Leong, V.Y.2    Lee, M.F.3
  • 26
    • 0023945481 scopus 로고
    • The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
    • Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31:315-24.
    • (1988) Arthritis Rheum , vol.31 , pp. 315-324
    • Arnett, F.C.1    Edworthy, S.M.2    Bloch, D.A.3
  • 27
    • 0344882568 scopus 로고    scopus 로고
    • Gene transfer of cytokine inhibitors into human synovial fibroblasts in the SCID mouse model
    • Müller-Ladner U, Evans CH, Franklin BN et al. Gene transfer of cytokine inhibitors into human synovial fibroblasts in the SCID mouse model. Arthritis Rheum 1999;42: 490-7.
    • (1999) Arthritis Rheum , vol.42 , pp. 490-497
    • Müller-Ladner, U.1    Evans, C.H.2    Franklin, B.N.3
  • 28
    • 34547767489 scopus 로고    scopus 로고
    • Fractalkine is a novel chemoattractant for rheumatoid arthritis fibroblast-like synoviocyte signaling through MAP kinases and Akt
    • Volin MV, Huynh N, Klosowska K, Chong KK, Woods JM. Fractalkine is a novel chemoattractant for rheumatoid arthritis fibroblast-like synoviocyte signaling through MAP kinases and Akt. Arthritis Rheum 2007;56: 2512-22.
    • (2007) Arthritis Rheum , vol.56 , pp. 2512-2522
    • Volin, M.V.1    Huynh, N.2    Klosowska, K.3    Chong, K.K.4    Woods, J.M.5
  • 29
    • 0034122050 scopus 로고    scopus 로고
    • Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor
    • Gravallese EM, Manning C, Tsay A et al. Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor. Arthritis Rheum 2000;43:250-8.
    • (2000) Arthritis Rheum , vol.43 , pp. 250-258
    • Gravallese, E.M.1    Manning, C.2    Tsay, A.3
  • 31
    • 77953203982 scopus 로고    scopus 로고
    • p21-activated kinase-1 promotes aggressive phenotype, cell proliferation, and invasion in gestational trophoblastic disease
    • Siu MK, Yeung MC, Zhang H et al. p21-activated kinase-1 promotes aggressive phenotype, cell proliferation, and invasion in gestational trophoblastic disease. Am J Pathol 2010;176:3015-22.
    • (2010) Am J Pathol , vol.176 , pp. 3015-3022
    • Siu, M.K.1    Yeung, M.C.2    Zhang, H.3
  • 32
    • 79960228959 scopus 로고    scopus 로고
    • Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration
    • Delorme-Walker VD, Peterson JR, Chernoff J et al. Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration. J Cell Biol 2011;193:1289-303.
    • (2011) J Cell Biol , vol.193 , pp. 1289-1303
    • Delorme-Walker, V.D.1    Peterson, J.R.2    Chernoff, J.3
  • 33
    • 73849104970 scopus 로고    scopus 로고
    • p21-activated kinase 1 participates in vascular remodeling in vitro and in vivo
    • Hinoki A, Kimura K, Higuchi S et al. p21-activated kinase 1 participates in vascular remodeling in vitro and in vivo. Hypertension 2010;55:161-5.
    • (2010) Hypertension , vol.55 , pp. 161-165
    • Hinoki, A.1    Kimura, K.2    Higuchi, S.3
  • 34
    • 0037192630 scopus 로고    scopus 로고
    • PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway
    • Coles LC, Shaw PE. PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway. Oncogene 2002;21:2236-44.
    • (2002) Oncogene , vol.21 , pp. 2236-2244
    • Coles, L.C.1    Shaw, P.E.2
  • 35
    • 4444255659 scopus 로고    scopus 로고
    • Cooperation of Rasand c-Myc-dependent pathways in regulating the growth and invasiveness of synovial fibroblasts in rheumatoid arthritis
    • Pap T, Nawrath M, Heinrich J et al. Cooperation of Rasand c-Myc-dependent pathways in regulating the growth and invasiveness of synovial fibroblasts in rheumatoid arthritis. Arthritis Rheum 2004;50:2794-802.
    • (2004) Arthritis Rheum , vol.50 , pp. 2794-2802
    • Pap, T.1    Nawrath, M.2    Heinrich, J.3
  • 36
    • 0346462998 scopus 로고    scopus 로고
    • p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells
    • Balasenthil S, Sahin AA, Barnes CJ et al. p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells. J Biol Chem 2004; 279:1422-8.
    • (2004) J Biol Chem , vol.279 , pp. 1422-1428
    • Balasenthil, S.1    Sahin, A.A.2    Barnes, C.J.3
  • 37
    • 65349086808 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated kinase-1
    • Zhou L, Yan C, Gieling RG et al. Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated kinase-1. BMC Immunol 2009;10:15.
    • (2009) BMC Immunol , vol.10 , pp. 15
    • Zhou, L.1    Yan, C.2    Gieling, R.G.3


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