Differential effects of dietary selenium (Se) and folate on methyl metabolism in liver and colon of rats

Biological Trace Element Research

Volumn 109, Issue 3, 2006, Pages 201-214

  Uthus, Eric O ^a   Ross, Sharon A ^b   Davis, Cindy D ^b  

^a GRAND FORKS HUMAN NUTRITION RESEARCH CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

DNA methylation; Folate; One carbon metabolism; Rat; Selenium

Indexed keywords

ADENOSYLHOMOCYSTEINASE; DNA METHYLTRANSFERASE; FOLIC ACID; GLYCINE METHYLTRANSFERASE; HOMOCYSTEINE; LIVER ENZYME; S ADENOSYLMETHIONINE; SELENITE; UNCLASSIFIED DRUG;

AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL COMPOSITION; COLON; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA METHYLATION; ENZYME ACTIVITY; ENZYME REGULATION; FEEDING; FOLIC ACID DEFICIENCY; LIVER METABOLISM; MALE; NONHUMAN; RAT; SELENIUM DEFICIENCY;

ANIMALS; COLON; DEFICIENCY DISEASES; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; FOLIC ACID; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLYCINE N-METHYLTRANSFERASE; HOMOCYSTEINE; LIVER; MALE; RATS; RATS, INBRED F344; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; SELENIUM;

ANIMALIA;

EID: 33646896927     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1385/BTER:109:3:201     Document Type: Article

References (44)

1. C. D. Davis and J. W. Finley, in Functional Foods and Nutraceuticals in Cancer Prevention, R. R. Watson, ed. Iowa State Press, Ames, 2003, pp. 55-85.
2. H. E. Ganther, Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase, Carcinogenesis 20, 1657-1666 (1999).
3. C. Ip, Y. Dong, and H. E. Ganther, New concepts in selenium chemoprevention, Cancer Metastasis Rev. 21, 281-289 (2002).
4. J. Lu and C. Jiang, Antiangiogenic activity of selenium in cancer chemoprevention: metabolite-specific effects, Nutr. Cancer 40, 64-73 (2001).
5. G. F. Combs, Jr., Chemopreventive mechanisms of selenium, Med Klin 94 (Suppl 3), 18-24 (1999).
6. C. D. Davis, E. O. Uthus, and J. W. Finley, Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon, J. Nutr. 130, 2903-2909 (2000).
7. E. S. Fiala, M. E. Staretz, G. A. Pandya, K. El-Bayoumy, and S. R. Hamilton, Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation, Carcinogenesis 19, 597-604 (1998).
8. Y. I. Kim, Folate, colorectal carcinogenesis, and DNA methylation: lessons from animal studies, Environ. Mol. Mutagen. 44, 10-25 (2004).
9. S. W. Choi and J. B. Mason, Folate and carcinogenesis: an integrated scheme, J. Nutr. 130, 129-132 (2000).
10. C. La Vecchia, E. Negri, C. Pelucchi, and S. Franceschi, Dietary folate and colorectal cancer, Int. J. Cancer 102, 545-547 (2002).
11. C. D. Davis and E. O. Uthus, Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats, J. Nutr. 133, 2907-2914 (2003).
12. P. G. Reeves, Components of the AIN-93 diets as improvements in the AIN-76A diet, J. Nutr. 127, 838S-841S (1997).
13. J. P. Issa, P. M. Vertino, J. Wu, et al., Increased cytosine DNA-methyltransferase activity during colon cancer progression, J. Natl. Cancer Inst. 85, 1235-1240 (1993).
14. J. Wagner, N. Claverie, and C. Danzin, A rapid high-performance liquid chromatographic procedure for the simultaneous determination of methionine, ethionine, S-adenosylmethionine, S-adenosylethionine, and the natural polyamines in rat tissues, Anal. Biochem. 140, 108-116 (1984).
15. G. L. Cantoni, in Methods in Enzymology, Vol. II, S. P. Colowick and N. O. Kaplan, eds., Academic Press, New York, 1955, pp. 254-256.
16. E. O. Uthus, Simultaneous detection of S-adenosylmethionine and S-adenosylhomocysteine in mouse and rat tissues by capillary electrophoresis, Electrophoresis 24, 1221-1226 (2003).
17. R. J. Cook and C. Wagner, Glycine N-methyltransferase is a folate binding protein of rat liver cytosol, Proc Natl Acad Sci USA 81, 3631-3634 (1984).
18. R. J. Cook, D. W. Horne, and C. Wagner, Effect of dietary methylgroup deficiency on one-carbon metabolism in rats, J. Nutr. 119, 612-617 (1989).
19. P. Durand, L. J. Fortin, S. Lussier-Cacan, J. Davignon, and D. Blache, Hyperhomocysteinemia induced by folic acid deficiency and methionine load - applications of a modified HPLC method, Clin. Chim. Acta 252, 83-93 (1996).
20. D. Paglia and W. Valentine, Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase, J. Lab. Clin. Med. 70, 158-169 (1967).
21. A. Holmgren and M. Bjornstedt, Thioredoxin and thioredoxin reductase, Methods Enzymol. 252, 199-208 (1995).
22. K. E. Hill, G. W. McCollum, and R. F. Burk, Determination of thioredoxin reductase activity in rat liver supernatant, Anal. Biochem. 253, 123-125 (1997).
23. M. J. Bunk and G. F. Combs, Jr., Evidence for an impairment in the conversion of methionine to cysteine in selenium-deficient chick, Proc. Soc. Exp. Biol. Med. 167, 87-93 (1981).
24. K. M. Halpin and D. H. Baker, Selenium deficiency and transsulfuration in the chick, J. Nutr. 114, 606-612 (1984).
25. K. E. Hill and R. F. Burk, Effect of selenium deficiency and vitamin E deficiency on glutathione metabolism in isolated rat hepatocytes, J. Biol. Chem. 257, 10668-10672 (1982).
26. K. E. Hill and R. F. Burk, Effect of selenium deficiency on the disposition of plasma glutathione, Arch. Biochem. Biophys. 240, 166-171 (1985).
27. K. E. Hill, R. F. Burk, and J. M. Lane, Effect of selenium depletion and repletion on plasma glutathione and glutathione-dependent enzymes in the rat, J. Nutr. 117, 99-104 (1987).
28. K. E. Hill, M. A. Taylor, and R. F. Burk, Influence of selenium deficiency on glutathione disulfide metabolism in isolated perfused rat heart, Biochim. Biophys. Acta. 923, 431-435 (1987).
29. E. O. Uthus, K. Yokoi, and C. D. Davis, Selenium deficiency in Fisher-344 rats decreases plasma and tissue homocysteine concentrations and alters plasma homocysteine and cysteine redox status, J. Nutr. 132, 1122-1128 (2002).
30. C. D. Davis and E. O. Uthus, Dietary selenium and azadeoxycytidine treatment affect dimethylhydrazine-induced aberrant crypt formation in rat colon and DNA methylation in HT-29 cells, J. Nutr. 132, 292-297 (2002).
31. B. Richardson and R. Yung, Role of DNA methylation in the regulation of cell function, J. Lab. Clin. Med. 134, 333-340 (1999).
32. C. D. Davis and E. O. Uthus, DNA methylation, cancer susceptibility, and nutrient interactions, Exp. Biol. Med. (Maywood) 229, 988-995 (2004).
33. J. D. Finkelstein, Pathways and regulation of homocysteine metabolism in mammals, Sem. Thromb. Hemost. 26, 219-225 (2000).
34. C. Wagner, W. T. Briggs, and R. J. Cook, Inhibition of glycine N-methyltransferase activity by folate derivatives: implications for regulation of methyl group metabolism, Biochem. Biophys. Res. Common. 127, 746-752 (1985).
35. F. M. Loehrer, W. E. Haefeli, C. P. Angst, G. Browne, G. Frick, and B. Fowler, Effect of methionine loading on 5-methyltetrahydrofolate, S-adenosylmethionine and S-adenosylhomocysteine in plasma of healthy humans, Clin. Sci. (Colch.) 91, 79-86 (1996).
36. K. Aida, M. Tawata, M. Negishi, and T. Onaya, Mouse glycine N-methyltransferase is sexually dimorphic and regulated by growth hormone, Horm. Metab. Res. 29, 646-649 (1997).
37. H. Ogawa, T. Gomi, F. Takusagawa, and M. Fujioka, Structure, function and physiological role of glycine N-methyltransferase, Int. J. Biochem. Cell. Biol. 30, 13-26 (1998).
38. M. Balaghi, D. W. Horne, and C. Wagner, Hepatic one-carbon metabolism in early folate deficiency in rats, Biochem. J. 291 (Pt 1), 145-149 (1993).
39. E. J. Yeo and C. Wagner, Tissue distribution of glycine N-methyltransferase, a major folate-binding protein of liver, Proc. Natl. Acad. Sci. USA 91, 210-214 (1994).
40. J. W. Finley, C. D. Davis, and Y. Feng, Selenium from high selenium broccoli protects rats from colon cancer, J Nutr 130, 2384-9 (2000).
41. H. H. Liu, K. H. Chen, Y. P. Shih, W. Y. Lui, F. H. Wong, and Y. M. Chen, Characterization of reduced expression of glycine N-methyltransferase in cancerous hepatic tissues using two newly developed monoclonal antibodies, J. Biomed. Sci. 10, 87-97 (2003).
42. J. E. Heady and S. J. Kerr, Alteration of glycine N-methyltransferase activity in fetal, adult, and tumor tissues, Cancer Res. 35, 640-643 (1975).
43. R. Bhat, C. Wagner, and E. Bresnick, The homodimeric form of glycine N-methyltransferase acts as a polycyclic aromatic hydrocarbon-binding receptor, Biochemistry 36, 9906-9910 (1997).
44. S. Y. Chen, J. R. Lin, R. Darbha, P. Lin, T. Y. Liu, and Y. M. Chen, Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway, Cancer Res. 64, 3617-3623 (2004).