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Volumn 56, Issue 3, 2012, Pages 157-163

Role of β-catenin expression in paediatric mesenchymal lesions: A tissue microarraybased immunohistochemical study

Author keywords

Beta catenin; Immunohistochemistry; Paediatric mesenchymal tumours; Wnt pathway

Indexed keywords


EID: 84863793831     PISSN: 1121760X     EISSN: None     Source Type: Journal    
DOI: 10.4081/ejh.2012.e25     Document Type: Article
Times cited : (12)

References (40)
  • 1
    • 42549164807 scopus 로고    scopus 로고
    • Wnt signalling and its impact on development and cancer
    • Klaus A, Birchmeier W. Wnt signalling and its impact on development and cancer. Nat Rev Cancer 2008;8:387-398.
    • (2008) Nat Rev Cancer , vol.8 , pp. 387-398
    • Klaus, A.1    Birchmeier, W.2
  • 2
    • 84861405462 scopus 로고    scopus 로고
    • The Wnts
    • reviews, 3001.1-3001.15
    • Miller JR. The Wnts. Genome Biol 2001;3:reviews3001.1-3001.15.
    • (2001) Genome Biol , vol.3
    • Miller, J.R.1
  • 3
    • 0032054828 scopus 로고    scopus 로고
    • Wnt signaling: Why is everything so negative?
    • Brown JD, Moon RT. Wnt signaling: why is everything so negative? Curr Opin Cell Biol 1998;10:182-187.
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 182-187
    • Brown, J.D.1    Moon, R.T.2
  • 4
    • 0034719170 scopus 로고    scopus 로고
    • GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin
    • Ikeda S, Kishida M, Matsuura Y, Usui H, Kikuchi A. GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin. Oncogene 2000;19:537-545.
    • (2000) Oncogene , vol.19 , pp. 537-545
    • Ikeda, S.1    Kishida, M.2    Matsuura, Y.3    Usui, H.4    Kikuchi, A.5
  • 5
    • 0033590172 scopus 로고    scopus 로고
    • Mechanism and function of signal transduction by the Wnt/Beta-catenin and Wnt/Ca+2 pathways
    • Miller JR, Hocking AM, Brown JD, Moon RT. Mechanism and function of signal transduction by the Wnt/Beta-catenin and Wnt/Ca+2 pathways. Oncogene 1999;18:7860-7872.
    • (1999) Oncogene , vol.18 , pp. 7860-7872
    • Miller, J.R.1    Hocking, A.M.2    Brown, J.D.3    Moon, R.T.4
  • 6
    • 0032729458 scopus 로고    scopus 로고
    • Signaling through Beta- catenin and Lef/Tcf
    • Novak A, Dedhar S. Signaling through Beta- catenin and Lef/Tcf. Cell Mol Life Sci 1999;56:523-537.
    • (1999) Cell Mol Life Sci , vol.56 , pp. 523-537
    • Novak, A.1    Dedhar, S.2
  • 7
    • 43049144313 scopus 로고    scopus 로고
    • Wnt signaling and stem cell control
    • Nusse R. Wnt signaling and stem cell control. Cell Res 2008;18:523-527.
    • (2008) Cell Res , vol.18 , pp. 523-527
    • Nusse, R.1
  • 8
    • 35748984680 scopus 로고    scopus 로고
    • Generation of multipotential mesendodermal progenitors from mouse embryonic stem cells via sustained Wnt pathway activation
    • Bakre MM, Hoi A, Mong JC, Koh YY, Wong KY, Stanton LW. Generation of multipotential mesendodermal progenitors from mouse embryonic stem cells via sustained Wnt pathway activation. J Biol Chem 2007; 282:31703-31712.
    • (2007) J Biol Chem , vol.282 , pp. 31703-31712
    • Bakre, M.M.1    Hoi, A.2    Mong, J.C.3    Koh, Y.Y.4    Wong, K.Y.5    Stanton, L.W.6
  • 10
    • 0033636075 scopus 로고    scopus 로고
    • The role of ECadherin- Catenin complex: More than an intercellular glue?
    • Harington KJ, Syrigos KN. The role of ECadherin- Catenin complex: more than an intercellular glue? Ann Surgic Oncol 2000; 7:783-788.
    • (2000) Ann Surgic Oncol , vol.7 , pp. 783-788
    • Harington, K.J.1    Syrigos, K.N.2
  • 11
    • 0035991607 scopus 로고    scopus 로고
    • Direct evidence for a role of beta-catenin/LEF-1 signaling pathway in induction of EMT
    • Kim K, Lu Z, Hay ED. Direct evidence for a role of beta-catenin/LEF-1 signaling pathway in induction of EMT. Cell Biol Int 2002;26:463-476.
    • (2002) Cell Biol Int , vol.26 , pp. 463-476
    • Kim, K.1    Lu, Z.2    Hay, E.D.3
  • 12
    • 0034644526 scopus 로고    scopus 로고
    • Linking colorectal cancer to Wnt signaling
    • Clevers H and Bienz M. Linking colorectal cancer to Wnt signaling. Cell 2000;103:311-320.
    • (2000) Cell , vol.103 , pp. 311-320
    • Clevers, H.1    Bienz, M.2
  • 13
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P. Wnt signaling and cancer. Genes Dev 2000;14:1837-1851.
    • (2000) Genes Dev , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 14
    • 0035087088 scopus 로고    scopus 로고
    • Prognostic significance of histologic grade and nuclear expression of beta-catenin in synovial sarcoma
    • Hasegawa T, Yokoyama R, Matsuno Y, Shimoda T, Hirohashi S. Prognostic significance of histologic grade and nuclear expression of beta-catenin in synovial sarcoma. Hum Pathol 2001;32:257-263.
    • (2001) Hum Pathol , vol.32 , pp. 257-263
    • Hasegawa, T.1    Yokoyama, R.2    Matsuno, Y.3    Shimoda, T.4    Hirohashi, S.5
  • 16
    • 0037474465 scopus 로고    scopus 로고
    • Activated Beta-catenin induces osteoblast differentiation of C3H10T1/2 cells and participated in BMP2 mediated signal transduction
    • Bain G, Müller T, Wang X, Papkoff J. Activated Beta-catenin induces osteoblast differentiation of C3H10T1/2 cells and participated in BMP2 mediated signal transduction. Biochem Biophys Res Commun 2003;301:84-91.
    • (2003) Biochem Biophys Res Commun , vol.301 , pp. 84-91
    • Bain, G.1    Müller, T.2    Wang, X.3    Papkoff, J.4
  • 17
    • 0031686139 scopus 로고    scopus 로고
    • Adenomatous polyposis coli gene mutation alters proliferation through its beta-catenin-regulatory function in aggressive fibromatosis (desmoid tumor)
    • Li C, Bapat B, Alman BA. Adenomatous polyposis coli gene mutation alters proliferation through its beta-catenin-regulatory function in aggressive fibromatosis (desmoid tumor). Am J Pathol 1998;153:709-714.
    • (1998) Am J Pathol , vol.153 , pp. 709-714
    • Li, C.1    Bapat, B.2    Alman, B.A.3
  • 18
    • 0031902681 scopus 로고    scopus 로고
    • Mutations of adenomatous polyposis coli (APC) gene are uncommon in sporadic desmoid tumours
    • Giarola M, Wells D, Mondini P, Pilotti S, Sala P, Azzarelli A, et al. Mutations of adenomatous polyposis coli (APC) gene are uncommon in sporadic desmoid tumours. Br J Cancer 1998;78:582-587.
    • (1998) Br J Cancer , vol.78 , pp. 582-587
    • Giarola, M.1    Wells, D.2    Mondini, P.3    Pilotti, S.4    Sala, P.5    Azzarelli, A.6
  • 19
    • 0030747976 scopus 로고    scopus 로고
    • Increased beta-catenin protein and somatic APC mutations in sporadic aggressive fibromatoses (desmoid tumors)
    • Alman BA, Li C, Pajerski ME, Diaz-Cano S, Wolfe HJ. Increased beta-catenin protein and somatic APC mutations in sporadic aggressive fibromatoses (desmoid tumors). Am J Pathol 1997;151:329-334.
    • (1997) Am J Pathol , vol.151 , pp. 329-334
    • Alman, B.A.1    Li, C.2    Pajerski, M.E.3    Diaz-Cano, S.4    Wolfe, H.J.5
  • 20
    • 0032234682 scopus 로고    scopus 로고
    • Frequent mutations in the beta-catenin gene in desmoid tumors from patients without familial adenomatous polyposis
    • Miyoshi Y, Iwao K, Nawa G, Yoshikawa H, Ochi T, Nakamura Y. Frequent mutations in the beta-catenin gene in desmoid tumors from patients without familial adenomatous polyposis. Oncol Res 1998;10:591-594.
    • (1998) Oncol Res , vol.10 , pp. 591-594
    • Miyoshi, Y.1    Iwao, K.2    Nawa, G.3    Yoshikawa, H.4    Ochi, T.5    Nakamura, Y.6
  • 21
    • 0033547361 scopus 로고    scopus 로고
    • Predominance of betacatenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor)
    • Tejpar S, Nollet F, Li C, Wunder JS, Michils G, dal Cin P, et al. Predominance of betacatenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor). Oncogene 1999;18:6615-6620.
    • (1999) Oncogene , vol.18 , pp. 6615-6620
    • Tejpar, S.1    Nollet, F.2    Li, C.3    Wunder, J.S.4    Michils, G.5    dal Cin, P.6
  • 22
    • 0033794514 scopus 로고    scopus 로고
    • Cytogenetic, clinical, and morphologic correlations in 78 cases of fibromatosis: A report from the CHAMP Study Group. CHromosomes And Morphology
    • De Wever I, Dal Cin P, Fletcher CD, Mandahl N, Mertens F, Mitelman F, et al. Cytogenetic, clinical, and morphologic correlations in 78 cases of fibromatosis: a report from the CHAMP Study Group. CHromosomes And Morphology. Mod Pathol 2000;13:1080-1085.
    • (2000) Mod Pathol , vol.13 , pp. 1080-1085
    • de Wever, I.1    dal Cin, P.2    Fletcher, C.D.3    Mandahl, N.4    Mertens, F.5    Mitelman, F.6
  • 23
    • 0034075935 scopus 로고    scopus 로고
    • A germline mutation at the extreme 3' end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of betacatenin in the desmoid tumor
    • Couture J, Mitri A, Lagace R, Smits R, Berk T, Bouchard HL, et al. A germline mutation at the extreme 3' end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of betacatenin in the desmoid tumor. Clin Genet 2000;57:205-212.
    • (2000) Clin Genet , vol.57 , pp. 205-212
    • Couture, J.1    Mitri, A.2    Lagace, R.3    Smits, R.4    Berk, T.5    Bouchard, H.L.6
  • 24
    • 0032851066 scopus 로고    scopus 로고
    • A novel case of a sporadic desmoid tumour with mutation of the beta catenin gene
    • Shitoh K, Konishi F, Iijima T, Ohdaira T, Sakai K, Kanazawa K, et al. A novel case of a sporadic desmoid tumour with mutation of the beta catenin gene. J Clin Pathol 1999;52:695-696.
    • (1999) J Clin Pathol , vol.52 , pp. 695-696
    • Shitoh, K.1    Konishi, F.2    Iijima, T.3    Ohdaira, T.4    Sakai, K.5    Kanazawa, K.6
  • 26
    • 42549164807 scopus 로고    scopus 로고
    • Wnt signaling and its impact on development and cancer
    • Klaus A, Birchmeier W. Wnt signaling and its impact on development and cancer. Nat Rev Cancer 2008;8:387-398.
    • (2008) Nat Rev Cancer , vol.8 , pp. 387-398
    • Klaus, A.1    Birchmeier, W.2
  • 27
    • 84874575134 scopus 로고    scopus 로고
    • Beta-catenin mediated Wnt signaling as a marker for characterization of human bone marrow-derived connective tissue progenitor
    • Available from
    • Hoover BA, Muschler G. Beta-catenin mediated Wnt signaling as a marker for characterization of human bone marrow-derived connective tissue progenitor. The Journal of Young Investigators 2005;12. Available from: http://www.jyi.org/research/re.php?id=190
    • (2005) The Journal of Young Investigators , pp. 12
    • Hoover, B.A.1    Muschler, G.2
  • 28
    • 33847321099 scopus 로고    scopus 로고
    • Expression of b-catenin and p53 are prognostic factors in deep aggressive fibromatosis
    • Gebert C, Hardes J, Kersting C, August C, Supper H, Winkelmann W, et al. Expression of b-catenin and p53 are prognostic factors in deep aggressive fibromatosis. Histopathol 2007;50:491-497.
    • (2007) Histopathol , vol.50 , pp. 491-497
    • Gebert, C.1    Hardes, J.2    Kersting, C.3    August, C.4    Supper, H.5    Winkelmann, W.6
  • 29
    • 55349092046 scopus 로고    scopus 로고
    • Tumorigenesis and Neoplastic Progression. Specific Mutations in the β-Catenin Gene (CTNNB1) Correlate with Local Recurrence in Sporadic Desmoid Tumors
    • Lazar AJF, Tuvin D, Hajibashi S, Habeeb S, Bolshakov S, Mayordomo-Aranda E, et al. Tumorigenesis and Neoplastic Progression. Specific Mutations in the β-Catenin Gene (CTNNB1) Correlate with Local Recurrence in Sporadic Desmoid Tumors. Am J Pathol 2008;173:1518-1527.
    • (2008) Am J Pathol , vol.173 , pp. 1518-1527
    • Lazar, A.J.F.1    Tuvin, D.2    Hajibashi, S.3    Habeeb, S.4    Bolshakov, S.5    Mayordomo-Aranda, E.6
  • 30
    • 0036787409 scopus 로고    scopus 로고
    • Beta-catenin immunohistochemistry separates mesenteric fibromatosis from gastrointestinal stromal tumor and sclerosing mesenteritis
    • Montgomery E, Torbenson MS, Kaushal M, Fisher C, Abraham SC. Beta-catenin immunohistochemistry separates mesenteric fibromatosis from gastrointestinal stromal tumor and sclerosing mesenteritis. Am J Surg Pathol 2002;26:1296-1301.
    • (2002) Am J Surg Pathol , vol.26 , pp. 1296-1301
    • Montgomery, E.1    Torbenson, M.S.2    Kaushal, M.3    Fisher, C.4    Abraham, S.C.5
  • 31
    • 70049095654 scopus 로고    scopus 로고
    • Beta-catenin expression in pediatric fibroblastic and myofibroblastic lesions: A study of 100 cases
    • Thway, K and Gibson, S and Ramsay, A, Sebire, NJ. Beta-catenin expression in pediatric fibroblastic and myofibroblastic lesions: a study of 100 cases. Pediatr Devel Pathol 2009;12:292-296.
    • (2009) Pediatr Devel Pathol , vol.12 , pp. 292-296
    • Thway, K.1    Gibson, S.2    Ramsay, A.3    Sebire, N.J.4
  • 32
    • 0034912650 scopus 로고    scopus 로고
    • Superficial fibromatoses are genetically distinct from deep fibromatoses
    • Montgomery E, Lee JH, Abraham SC, Wu TT. Superficial fibromatoses are genetically distinct from deep fibromatoses. Mod Pathol 2001;14:695-701.
    • (2001) Mod Pathol , vol.14 , pp. 695-701
    • Montgomery, E.1    Lee, J.H.2    Abraham, S.C.3    Wu, T.T.4
  • 33
    • 0033658259 scopus 로고    scopus 로고
    • Prognostic value of the preserved expression of the Ecadherin and catenin families of adhesion molecules and of beta-catenin mutations in synovial sarcoma
    • Saito T, Oda Y, Sakamoto A, Tamiya S, Kinukawa N, Hayashi K, et al. Prognostic value of the preserved expression of the Ecadherin and catenin families of adhesion molecules and of beta-catenin mutations in synovial sarcoma. J Pathol 2000;192: 342-350.
    • (2000) J Pathol , vol.192 , pp. 342-350
    • Saito, T.1    Oda, Y.2    Sakamoto, A.3    Tamiya, S.4    Kinukawa, N.5    Hayashi, K.6
  • 34
    • 0036888309 scopus 로고    scopus 로고
    • Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma
    • Haydon RC, Deyrup A, Ishikawa A, Heck R, Jiang W, Zhou L, et al. Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma. Int J Cancer 2002;102:338-342.
    • (2002) Int J Cancer , vol.102 , pp. 338-342
    • Haydon, R.C.1    Deyrup, A.2    Ishikawa, A.3    Heck, R.4    Jiang, W.5    Zhou, L.6
  • 35
    • 0036770453 scopus 로고    scopus 로고
    • Beta-catenin dedifferentiated liposarcoma and malignant fibrous histiocytoma
    • Sakamoto A, Oda Y, Adachi T, Saito T, Tamiya S, Iwamoto Y, et al. Beta-catenin dedifferentiated liposarcoma and malignant fibrous histiocytoma. Arch Pathol Lab Med 2002;126:1071-10478.
    • (2002) Arch Pathol Lab Med , vol.126 , pp. 1071-10478
    • Sakamoto, A.1    Oda, Y.2    Adachi, T.3    Saito, T.4    Tamiya, S.5    Iwamoto, Y.6
  • 36
    • 0033795924 scopus 로고    scopus 로고
    • Beta-catenin in soft-tissue sarcomas: Expression is related to proliferative activity in high-grade sarcomas
    • Kuhnen C, Herter P, Muller O, Muehlberger T, Krause L, Homann H, et al. Beta-catenin in soft-tissue sarcomas: expression is related to proliferative activity in high-grade sarcomas. Mod Pathol 2000;13:1005-1013.
    • (2000) Mod Pathol , vol.13 , pp. 1005-1013
    • Kuhnen, C.1    Herter, P.2    Muller, O.3    Muehlberger, T.4    Krause, L.5    Homann, H.6
  • 37
    • 0029156014 scopus 로고
    • Sclerosing epithelioid fibrosarcoma. A variant of fibrosarcoma simulating carcinoma
    • Meis-Kindblom JM, Kindblom LG, Enzinger FM. Sclerosing epithelioid fibrosarcoma. A variant of fibrosarcoma simulating carcinoma. Am J Surg Pathol 1995;19:979-993.
    • (1995) Am J Surg Pathol , vol.19 , pp. 979-993
    • Meis-Kindblom, J.M.1    Kindblom, L.G.2    Enzinger, F.M.3
  • 38
    • 17744378169 scopus 로고    scopus 로고
    • Nuclear beta-catenin expression distinguishes deep fibromatosis from other benign and malignant fibroblastic and myofibroblastic lesions
    • Bhattacharya B, Dilworth HP, Iacobuzio-Donahue C, Ricci F, Weber K, Furlong MA, et al. Nuclear beta-catenin expression distinguishes deep fibromatosis from other benign and malignant fibroblastic and myofibroblastic lesions. Am J Surg Pathol 2005;29:653-659.
    • (2005) Am J Surg Pathol , vol.29 , pp. 653-659
    • Bhattacharya, B.1    Dilworth, H.P.2    Iacobuzio-Donahue, C.3    Ricci, F.4    Weber, K.5    Furlong, M.A.6
  • 39
    • 34848826864 scopus 로고    scopus 로고
    • Mini- Review. Epithelial-mesenchymal and mesenchymal- epithelial transitions in carcinoma progression
    • Hugo H, Ackland ML, Blick T, Lawrence MG, Clements JA, Williams ED, et al. Mini- Review. Epithelial-mesenchymal and mesenchymal- epithelial transitions in carcinoma progression. J Cell Physiol 2007;213: 374-383.
    • (2007) J Cell Physiol , vol.213 , pp. 374-383
    • Hugo, H.1    Ackland, M.L.2    Blick, T.3    Lawrence, M.G.4    Clements, J.A.5    Williams, E.D.6
  • 40
    • 2342643464 scopus 로고    scopus 로고
    • β-Catenin and TGF β signalling cooperate to maintain a mesenchymal phenotype after FosERinduced epithelial to mesenchymal transition
    • Eger A, Stockinger A, Park J, Langkopf E, Mikula M, Gotzmann J, et al. β-Catenin and TGF β signalling cooperate to maintain a mesenchymal phenotype after FosERinduced epithelial to mesenchymal transition. Oncogene 2004;23:2672-2680.
    • (2004) Oncogene , vol.23 , pp. 2672-2680
    • Eger, A.1    Stockinger, A.2    Park, J.3    Langkopf, E.4    Mikula, M.5    Gotzmann, J.6


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