Prolonged Urinary Detection Times of EtG and EtS in Patients with Decreased Renal Function

Alcoholism: Clinical and Experimental Research

Volumn 36, Issue 7, 2012, Pages 1148-1151

  Høiseth, Gudrun ^a,b   Nordal, Kristin ^a   Pettersen, Eirik ^c   Mørland, Jørg ^a  

^a NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^b DIAKONHJEMMET HOSPITAL   (Norway)

^c AKERSHUS UNIVERSITY HOSPITAL   (Norway)

Author keywords

Alcohol; Ethyl glucuronide; Ethyl sulphate; Kidney function

Indexed keywords

ALCOHOL; ETHYL GLUCURONIDE; ETHYL SULPHATE; SULFATE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HUMAN; KIDNEY DYSFUNCTION; KIDNEY FUNCTION TEST; MALE; PRIORITY JOURNAL; URINALYSIS;

ADULT; AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; BIOLOGICAL MARKERS; ETHANOL; FEMALE; GLUCURONATES; HUMANS; KIDNEY DISEASES; KIDNEY FUNCTION TESTS; MALE; MIDDLE AGED; SULFURIC ACID ESTERS; TIME FACTORS;

EID: 84863785642     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2011.01713.x     Document Type: Article

References (20)

1. Bodd E, Jacobsen D, Lund E, Ripel A, Morland J, Wiik-Larsen E (1990) Morphine-6-glucuronide might mediate the prolonged opioid effect of morphine in acute renal failure. Hum Exp Toxicol 9:317-321.
2. Borucki K, Schreiner R, Dierkes J, Jachau K, Krause D, Westphal S, Wurst FM, Luley C, Schmidt-Gayk H (2005) Detection of recent ethanol intake with new markers: comparison of fatty acid ethyl esters in serum and of ethyl glucuronide and the ratio of 5-hydroxytryptophol to 5-hydroxyindole acetic acid in urine. Alcohol Clin Exp Res 29:781-787.
3. Dahl H, Stephanson N, Beck O, Helander A (2002) Comparison of urinary excretion characteristics of ethanol and ethyl glucuronide. J Anal Toxicol 26:201-204.
4. Foster-Swanson A, Swartzentruber M, Roberts P (1994) Reference interval studies of the rate-blanked creatinine/Jaffe method on BM/Hitachi systems in six U.S. laboratories. Clin Chem 40:1057.
5. Hanna MH, D'Costa F, Peat SJ, Fung C, Venkat N, Zilkha TR, Davies S (1993) Morphine-6-glucuronide disposition in renal impairment. Br J Anaesth 70:511-514.
6. Helander A, Bottcher M, Fehr C, Dahmen N, Beck O (2009) Detection times for urinary ethyl glucuronide and ethyl sulfate in heavy drinkers during alcohol detoxification. Alcohol Alcohol 44:55-61.
7. Hoiseth G, Bernard JP, Karinen R, Johnsen L, Helander A, Christophersen AS, Morland J (2007) A pharmacokinetic study of ethyl glucuronide in blood and urine: applications to forensic toxicology. Forensic Sci Int 172:119-124.
8. Hoiseth G, Bernard JP, Stephanson N, Normann PT, Christophersen AS, Morland J, Helander A (2008) Comparison between the urinary alcohol markers EtG, EtS, and GTOL/5-HIAA in a controlled drinking experiment. Alcohol Alcohol 43:187-191.
9. Hoiseth G, Morini L, Polettini A, Christophersen A, Morland J (2009a) Blood kinetics of ethyl glucuronide and ethyl sulphate in heavy drinkers during alcohol detoxification. Forensic Sci Int 188:52-56.
10. Hoiseth G, Yttredal B, Karinen R, Gjerde H, Christophersen A (2009b) Levels of ethyl glucuronide and ethyl sulphate in oral fluid, blood and urine after use of mouth wash and ingestion of non-alcoholic wine. J Anal Toxicol 34:84-88.
11. Kristoffersen L, Smith-Kielland A (2005) An automated alcohol dehydrogenase method for ethanol quantification in urine and whole blood. J Anal Toxicol 29:387-389.
12. Lande RG, Marin B, Chang AS (2011) Clinical application of ethyl glucuronide testing in the U.S. Army. J Addict Dis 30:39-44.
13. Osborne R, Joel S, Grebenik K, Trew D, Slevin M (1993) The pharmacokinetics of morphine and morphine glucuronides in kidney failure. Clin Pharmacol Ther 54:158-167.
14. Palmer RB (2009) A review of the use of ethyl glucuronide as a marker for ethanol consumption in forensic and clinical medicine. Semin Diagn Pathol 26:18-27.
15. Prescott LF, Wright N (1973) The effects of hepatic and renal damage on paracetamol metabolism and excretion following overdosage. A pharmacokinetic study. Br J Pharmacol 49:602-613.
16. Rule AD (2007) Understanding estimated glomerular filtration rate: implications for identifying chronic kidney disease. Curr Opin Nephrol Hypertens 16:242-249.
17. Rustad P, Felding P, Franzson L, Kairisto V, Lahti A, Martensson A, Hyltoft PP, Simonsson P, Steensland H, Uldall A (2004) The Nordic Reference Interval Project 2000: recommended reference intervals for 25 common biochemical properties. Scand J Clin Lab Invest 64:271-284.
18. Wurst FM, Dresen S, Allen JP, Wiesbeck G, Graf M, Weinmann W (2006) Ethyl sulphate: a direct ethanol metabolite reflecting recent alcohol consumption. Addiction 101:204-211.
19. Wurst FM, Kempter C, Seidl S, Alt A (1999) Ethyl glucuronide-a marker of alcohol consumption and a relapse marker with clinical and forensic implications. Alcohol Alcohol 34:71-77.
20. Wurst FM, Wiesbeck GA, Metzger JW, Weinmann W (2004) On sensitivity, specificity, and the influence of various parameters on ethyl glucuronide levels in urine-results from the WHO/ISBRA study. Alcohol Clin Exp Res 28:1220-1228.