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Volumn 318, Issue 15, 2012, Pages 1832-1843

Downregulation of HMGA2 by the pan-deacetylase inhibitor panobinostat is dependent on hsa-let-7b expression in liver cancer cell lines

Author keywords

HMGA2; Hsa let 7b; Liver cancer; Oncogenes; Pan deacetylase inhibitor

Indexed keywords

HIGH MOBILITY GROUP A2 PROTEIN; HSA LET 7B PROTEIN; MICRORNA; OLIGONUCLEOTIDE; PANOBINOSTAT; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84863781353     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2012.04.018     Document Type: Article
Times cited : (65)

References (62)
  • 2
    • 78650004201 scopus 로고    scopus 로고
    • MicroRNA: biogenesis, function and role in cancer
    • Macfarlane L.A., Murphy P.R. MicroRNA: biogenesis, function and role in cancer. Curr. Genomics 2010, 11:537-561.
    • (2010) Curr. Genomics , vol.11 , pp. 537-561
    • Macfarlane, L.A.1    Murphy, P.R.2
  • 4
    • 60149084560 scopus 로고    scopus 로고
    • MicroRNAs and cancer: short RNAs go a long way
    • Ventura A., Jacks T. MicroRNAs and cancer: short RNAs go a long way. Cell 2009, 136:586-591.
    • (2009) Cell , vol.136 , pp. 586-591
    • Ventura, A.1    Jacks, T.2
  • 6
    • 70349976210 scopus 로고    scopus 로고
    • MicroRNAs: novel regulators in the hallmarks of human cancer
    • Ruan K., Fang X., Ouyang G. MicroRNAs: novel regulators in the hallmarks of human cancer. Cancer Lett. 2009, 285:116-126.
    • (2009) Cancer Lett. , vol.285 , pp. 116-126
    • Ruan, K.1    Fang, X.2    Ouyang, G.3
  • 9
    • 68049122037 scopus 로고    scopus 로고
    • Binding the mammalian high mobility group protein AT-hook 2 to AT-rich deoxyoligonucleotides: enthalpy-entropy compensation
    • Joynt S., Morillo V., Leng F. Binding the mammalian high mobility group protein AT-hook 2 to AT-rich deoxyoligonucleotides: enthalpy-entropy compensation. Biophys. J. 2009, 96:4144-4152.
    • (2009) Biophys. J. , vol.96 , pp. 4144-4152
    • Joynt, S.1    Morillo, V.2    Leng, F.3
  • 10
    • 79955020072 scopus 로고    scopus 로고
    • Chromatin immunoprecipitation to analyze DNA binding sites of HMGA2
    • Winter N., Nimzyk R., Bosche C., Meyer A., Bullerdiek J. Chromatin immunoprecipitation to analyze DNA binding sites of HMGA2. PLoS One 2011, 6:e18837.
    • (2011) PLoS One , vol.6
    • Winter, N.1    Nimzyk, R.2    Bosche, C.3    Meyer, A.4    Bullerdiek, J.5
  • 11
    • 36448992338 scopus 로고    scopus 로고
    • Roles of HMGA proteins in cancer
    • Fusco A., Fedele M. Roles of HMGA proteins in cancer. Nat. Rev. Cancer 2007, 7:899-910.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 899-910
    • Fusco, A.1    Fedele, M.2
  • 13
    • 79959419265 scopus 로고    scopus 로고
    • High-mobility group A2 protein modulates hTERT transcription to promote tumorigenesis
    • Li A.Y., Lin H.H., Kuo C.Y., Shih H.M., Wang C.C., Yen Y., Ann D.K. High-mobility group A2 protein modulates hTERT transcription to promote tumorigenesis. Mol. Cell. Biol. 2011, 31:2605-2617.
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 2605-2617
    • Li, A.Y.1    Lin, H.H.2    Kuo, C.Y.3    Shih, H.M.4    Wang, C.C.5    Yen, Y.6    Ann, D.K.7
  • 14
    • 0029018303 scopus 로고
    • Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains
    • Ashar H.R., Fejzo M.S., Tkachenko A., Zhou X., Fletcher J.A., Weremowicz S., Morton C.C., Chada K. Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains. Cell 1995, 82:57-65.
    • (1995) Cell , vol.82 , pp. 57-65
    • Ashar, H.R.1    Fejzo, M.S.2    Tkachenko, A.3    Zhou, X.4    Fletcher, J.A.5    Weremowicz, S.6    Morton, C.C.7    Chada, K.8
  • 16
    • 70349850944 scopus 로고    scopus 로고
    • HMGA2-NFIB fusion in a pediatric intramuscular lipoma: a novel case of NFIB alteration in a large deep-seated adipocytic tumor
    • Pierron A., Fernandez C., Saada E., Keslair F., Hery G., Zattara H., Pedeutour F. HMGA2-NFIB fusion in a pediatric intramuscular lipoma: a novel case of NFIB alteration in a large deep-seated adipocytic tumor. Cancer Genet. Cytogenet. 2009, 195:66-70.
    • (2009) Cancer Genet. Cytogenet. , vol.195 , pp. 66-70
    • Pierron, A.1    Fernandez, C.2    Saada, E.3    Keslair, F.4    Hery, G.5    Zattara, H.6    Pedeutour, F.7
  • 24
    • 59649121124 scopus 로고    scopus 로고
    • Frequent overexpression of HMGA1 and 2 in gastroenteropancreatic neuroendocrine tumours and its relationship to let-7 downregulation
    • Rahman M.M., Qian Z.R., Wang E.L., Sultana R., Kudo E., Nakasono M., Hayashi T., Kakiuchi S., Sano T. Frequent overexpression of HMGA1 and 2 in gastroenteropancreatic neuroendocrine tumours and its relationship to let-7 downregulation. Br. J. Cancer 2009, 100:501-510.
    • (2009) Br. J. Cancer , vol.100 , pp. 501-510
    • Rahman, M.M.1    Qian, Z.R.2    Wang, E.L.3    Sultana, R.4    Kudo, E.5    Nakasono, M.6    Hayashi, T.7    Kakiuchi, S.8    Sano, T.9
  • 26
    • 70350017965 scopus 로고    scopus 로고
    • Gene expressions of HMGI-C and HMGI(Y) are associated with stage and metastasis in colorectal cancer
    • Huang M.L., Chen C.C., Chang L.C. Gene expressions of HMGI-C and HMGI(Y) are associated with stage and metastasis in colorectal cancer. Int. J. Colorectal. Dis. 2009, 24:1281-1286.
    • (2009) Int. J. Colorectal. Dis. , vol.24 , pp. 1281-1286
    • Huang, M.L.1    Chen, C.C.2    Chang, L.C.3
  • 27
    • 62549159932 scopus 로고    scopus 로고
    • HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cells
    • Watanabe S., Ueda Y., Akaboshi S., Hino Y., Sekita Y., Nakao M. HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cells. Am. J. Pathol. 2009, 174:854-868.
    • (2009) Am. J. Pathol. , vol.174 , pp. 854-868
    • Watanabe, S.1    Ueda, Y.2    Akaboshi, S.3    Hino, Y.4    Sekita, Y.5    Nakao, M.6
  • 29
    • 0345601951 scopus 로고    scopus 로고
    • HMGI(Y) gene expression in colorectal cancer: comparison with some histological typing, grading, and clinical staging
    • Balcerczak M., Pasz-Walczak G., Balcerczak E., Wojtylak M., Kordek R., Mirowski M. HMGI(Y) gene expression in colorectal cancer: comparison with some histological typing, grading, and clinical staging. Pathol. Res. Pract. 2003, 199:641-646.
    • (2003) Pathol. Res. Pract. , vol.199 , pp. 641-646
    • Balcerczak, M.1    Pasz-Walczak, G.2    Balcerczak, E.3    Wojtylak, M.4    Kordek, R.5    Mirowski, M.6
  • 30
    • 77956270554 scopus 로고    scopus 로고
    • Lin-28B expression promotes transformation and invasion in human hepatocellular carcinoma
    • Wang Y.C., Chen Y.L., Yuan R.H., Pan H.W., Yang W.C., Hsu H.C., Jeng Y.M. Lin-28B expression promotes transformation and invasion in human hepatocellular carcinoma. Carcinogenesis 2010, 31:1516-1522.
    • (2010) Carcinogenesis , vol.31 , pp. 1516-1522
    • Wang, Y.C.1    Chen, Y.L.2    Yuan, R.H.3    Pan, H.W.4    Yang, W.C.5    Hsu, H.C.6    Jeng, Y.M.7
  • 32
    • 58149234169 scopus 로고    scopus 로고
    • Molecular therapy for the treatment of hepatocellular carcinoma
    • Greten T.F., Korangy F., Manns M.P., Malek N.P. Molecular therapy for the treatment of hepatocellular carcinoma. Br. J. Cancer 2009, 100:19-23.
    • (2009) Br. J. Cancer , vol.100 , pp. 19-23
    • Greten, T.F.1    Korangy, F.2    Manns, M.P.3    Malek, N.P.4
  • 33
    • 34250171437 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: signalling towards p21cip1/waf1
    • Ocker M., Schneider-Stock R. Histone deacetylase inhibitors: signalling towards p21cip1/waf1. Int. J. Biochem. Cell Biol. 2007, 39:1367-1374.
    • (2007) Int. J. Biochem. Cell Biol. , vol.39 , pp. 1367-1374
    • Ocker, M.1    Schneider-Stock, R.2
  • 34
    • 35449007304 scopus 로고    scopus 로고
    • Apoptosis: potential therapeutic targets for new drug discovery
    • Jana S., Paliwal J. Apoptosis: potential therapeutic targets for new drug discovery. Curr. Med. Chem. 2007, 14:2369-2379.
    • (2007) Curr. Med. Chem. , vol.14 , pp. 2369-2379
    • Jana, S.1    Paliwal, J.2
  • 35
    • 67649305191 scopus 로고    scopus 로고
    • Epigenetics in cancer: targeting chromatin modifications
    • Ellis L., Atadja P.W., Johnstone R.W. Epigenetics in cancer: targeting chromatin modifications. Mol. Cancer Ther. 2009, 8:1409-1420.
    • (2009) Mol. Cancer Ther. , vol.8 , pp. 1409-1420
    • Ellis, L.1    Atadja, P.W.2    Johnstone, R.W.3
  • 36
    • 79959337199 scopus 로고    scopus 로고
    • Deacetylase inhibitors-focus on non-histone targets and effects
    • Ocker M. Deacetylase inhibitors-focus on non-histone targets and effects. World J. Biol. Chem. 2010, 1:55-61.
    • (2010) World J. Biol. Chem. , vol.1 , pp. 55-61
    • Ocker, M.1
  • 38
    • 78649357109 scopus 로고    scopus 로고
    • Mature microRNAs identified in highly purified nuclei from HCT116 colon cancer cells
    • Park C.W., Zeng Y., Zhang X., Subramanian S., Steer C.J. Mature microRNAs identified in highly purified nuclei from HCT116 colon cancer cells. RNA Biol. 2010, 7:606-614.
    • (2010) RNA Biol. , vol.7 , pp. 606-614
    • Park, C.W.1    Zeng, Y.2    Zhang, X.3    Subramanian, S.4    Steer, C.J.5
  • 39
    • 69849110970 scopus 로고    scopus 로고
    • Panobinostat (LBH589): a potent pan-deacetylase inhibitor with promising activity against hematologic and solid tumors
    • Prince H.M., Bishton M.J., Johnstone R.W. Panobinostat (LBH589): a potent pan-deacetylase inhibitor with promising activity against hematologic and solid tumors. Future Oncol. 2009, 5:601-612.
    • (2009) Future Oncol. , vol.5 , pp. 601-612
    • Prince, H.M.1    Bishton, M.J.2    Johnstone, R.W.3
  • 41
    • 60149088848 scopus 로고    scopus 로고
    • Origins and mechanisms of miRNAs and siRNAs
    • Carthew R.W., Sontheimer E.J. Origins and mechanisms of miRNAs and siRNAs. Cell 2009, 136:642-655.
    • (2009) Cell , vol.136 , pp. 642-655
    • Carthew, R.W.1    Sontheimer, E.J.2
  • 42
    • 33846188098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • Zhang B., Pan X., Cobb G.P., Anderson T.A. MicroRNAs as oncogenes and tumor suppressors. Dev. Biol. 2007, 302:1-12.
    • (2007) Dev. Biol. , vol.302 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4
  • 43
    • 80052399992 scopus 로고    scopus 로고
    • Cooperative control of tumor suppressor genes by a network of oncogenic microRNAs
    • Mavrakis K.J., Leslie C.S., Wendel H.G. Cooperative control of tumor suppressor genes by a network of oncogenic microRNAs. Cell Cycle 2011, 10.
    • (2011) Cell Cycle , vol.10
    • Mavrakis, K.J.1    Leslie, C.S.2    Wendel, H.G.3
  • 44
    • 80053335068 scopus 로고    scopus 로고
    • Big roles of microRNAs in tumorigenesis and tumor development
    • Tie J., Fan D. Big roles of microRNAs in tumorigenesis and tumor development. Histol. Histopathol. 2011, 26:1353-1361.
    • (2011) Histol. Histopathol. , vol.26 , pp. 1353-1361
    • Tie, J.1    Fan, D.2
  • 47
    • 72849147757 scopus 로고    scopus 로고
    • Epigenetics, miRNAs, and human cancer: a new chapter in human gene regulation
    • Valeri N., Vannini I., Fanini F., Calore F., Adair B., Fabbri M. Epigenetics, miRNAs, and human cancer: a new chapter in human gene regulation. Mamm. Genome 2009, 20:573-580.
    • (2009) Mamm. Genome , vol.20 , pp. 573-580
    • Valeri, N.1    Vannini, I.2    Fanini, F.3    Calore, F.4    Adair, B.5    Fabbri, M.6
  • 48
    • 32944462300 scopus 로고    scopus 로고
    • Rapid alteration of microRNA levels by histone deacetylase inhibition
    • Scott G.K., Mattie M.D., Berger C.E., Benz S.C., Benz C.C. Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res. 2006, 66:1277-1281.
    • (2006) Cancer Res. , vol.66 , pp. 1277-1281
    • Scott, G.K.1    Mattie, M.D.2    Berger, C.E.3    Benz, S.C.4    Benz, C.C.5
  • 50
    • 77956279586 scopus 로고    scopus 로고
    • The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex
    • Boominathan L. The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex. PLoS One 2010, 5:e10615.
    • (2010) PLoS One , vol.5
    • Boominathan, L.1
  • 52
    • 78650639749 scopus 로고    scopus 로고
    • Emerging complexity of microRNA generation cascades
    • Suzuki H.I., Miyazono K. Emerging complexity of microRNA generation cascades. J. Biochem. 2011, 149:15-25.
    • (2011) J. Biochem. , vol.149 , pp. 15-25
    • Suzuki, H.I.1    Miyazono, K.2
  • 53
    • 77953032534 scopus 로고    scopus 로고
    • Emerging paradigms of regulated microRNA processing
    • Newman M.A., Hammond S.M. Emerging paradigms of regulated microRNA processing. Genes Dev. 2010, 24:1086-1092.
    • (2010) Genes Dev. , vol.24 , pp. 1086-1092
    • Newman, M.A.1    Hammond, S.M.2
  • 54
    • 47949100595 scopus 로고    scopus 로고
    • Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
    • Newman M.A., Thomson J.M., Hammond S.M. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 2008, 14:1539-1549.
    • (2008) RNA , vol.14 , pp. 1539-1549
    • Newman, M.A.1    Thomson, J.M.2    Hammond, S.M.3
  • 57
    • 78651359790 scopus 로고    scopus 로고
    • Histone deacetylase regulates high mobility group A2-targeting microRNAs in human cord blood-derived multipotent stem cell aging
    • Lee S., Jung J.W., Park S.B., Roh K., Lee S.Y., Kim J.H., Kang S.K., Kang K.S. Histone deacetylase regulates high mobility group A2-targeting microRNAs in human cord blood-derived multipotent stem cell aging. Cell. Mol. Life Sci. 2011, 68:325-336.
    • (2011) Cell. Mol. Life Sci. , vol.68 , pp. 325-336
    • Lee, S.1    Jung, J.W.2    Park, S.B.3    Roh, K.4    Lee, S.Y.5    Kim, J.H.6    Kang, S.K.7    Kang, K.S.8
  • 59
    • 33749657826 scopus 로고    scopus 로고
    • Critical role of the HMGA2 gene in pituitary adenomas
    • Fedele M., Pierantoni G.M., Visone R., Fusco A. Critical role of the HMGA2 gene in pituitary adenomas. Cell Cycle 2006, 5:2045-2048.
    • (2006) Cell Cycle , vol.5 , pp. 2045-2048
    • Fedele, M.1    Pierantoni, G.M.2    Visone, R.3    Fusco, A.4
  • 60
    • 34248373845 scopus 로고    scopus 로고
    • E2F1 activation is responsible for pituitary adenomas induced by HMGA2 gene overexpression
    • Fedele M., Pierantoni G.M., Visone R., Fusco A. E2F1 activation is responsible for pituitary adenomas induced by HMGA2 gene overexpression. Cell Div. 2006, 1:17.
    • (2006) Cell Div. , vol.1 , pp. 17
    • Fedele, M.1    Pierantoni, G.M.2    Visone, R.3    Fusco, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.