Mechanism of inhibition of the glutamate transporter EAAC1 by the conformationally constrained glutamate analogue (+)-HIP-B

Biochemistry

Volumn 51, Issue 27, 2012, Pages 5486-5495

  Callender, Randolph ^a   Gameiro, Armanda ^a   Pinto, Andrea ^b   De Micheli, Carlo ^b   Grewer, Christof ^a  

^a BINGHAMTON UNIVERSITY   (United States)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EXTRACELLULAR; GLUTAMATE TRANSPORTERS; MAMMALIAN BRAIN; SUBSTRATE-BINDING SITES;

CARBOXYLIC ACIDS; MAMMALS;

AMINO ACIDS;

3 HYDROXY 4,5,6,6A TETRAHYDRO 3AH PYRROLO[3,4 D]ISOXAZOLE 6 CARBOXYLIC ACID; ASPARTIC ACID; CARBOXYLIC ACID DERIVATIVE; DEXTRO LEVO THREO BETA BENZYLOXYASPARTIC ACID; EXCITATORY AMINO ACID TRANSPORTER 3; GLUTAMIC ACID; GLUTAMINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONDUCTANCE; CONTROLLED STUDY; MOLECULAR MECHANICS; MUTANT; PRIORITY JOURNAL; PROTEIN CONFORMATION;

BINDING SITES; BIOLOGICAL TRANSPORT; CARBOXYLIC ACIDS; EXCITATORY AMINO ACID TRANSPORTER 3; GLUTAMATES; HEK293 CELLS; HUMANS; KINETICS; MOLECULAR CONFORMATION; MUTATION; OXAZOLES;

MAMMALIA;

EID: 84863769896     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3006048     Document Type: Article

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