Two conformational changes are associated with glutamate translocation by the glutamate transporter EAAC1

Biochemistry

Volumn 46, Issue 31, 2007, Pages 9007-9018

  Mim, Carsten ^a,b   Tao, Zhen ^a   Grewer, Christof ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION BARRIERS; CONFORMATIONAL CHANGES; GLUTAMATE TRANSLOCATION;

BINDING ENERGY; ENTHALPY; PARAMETER ESTIMATION; THERMAL EFFECTS;

PROTEINS;

CARRIER PROTEIN; GLUTAMATE TRANSPORTER; GLUTAMATE TRANSPORTER EAAC1; GLUTAMIC ACID; SODIUM; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DIFFUSION; ENTHALPY; ENTROPY; HUMAN; HUMAN CELL; MEMBRANE TRANSPORT; PRIORITY JOURNAL; STEADY STATE; TEMPERATURE DEPENDENCE; THERMODYNAMICS;

ALGORITHMS; ASPARTIC ACID; BIOLOGICAL TRANSPORT; CELL LINE; EXCITATORY AMINO ACID TRANSPORTER 3; EXCITATORY AMINO ACID TRANSPORTER 4; GLUTAMATES; GLUTAMIC ACID; HUMANS; INDOLES; KINETICS; MEMBRANE POTENTIALS; MODELS, MOLECULAR; PATCH-CLAMP TECHNIQUES; PROTEIN BINDING; PROTEIN CONFORMATION; SODIUM; TEMPERATURE; THERMODYNAMICS; TRANSFECTION;

BACTERIA (MICROORGANISMS);

EID: 34547815544     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi7005465     Document Type: Article

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