Glycosylation of the sodium channel β4 subunit is developmentally regulated and involves in neuritic degeneration

International Journal of Biological Sciences

Volumn 8, Issue 5, 2012, Pages 630-639

  Zhou, Ting Ting ^a   Zhang, Zhen Wei ^a   Liu, Jun ^b   Zhang, Jian Peng ^a   Jiao, Bing Hua ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

Filopodia like protrusion; Glycosylation; Neurite outgrowth; Parkinson's disease; Voltage gated sodium channel 4 subunit

Indexed keywords

SCN4B PROTEIN, MOUSE; SODIUM CHANNEL;

ANIMAL; ARTICLE; BIOSYNTHESIS; BRAIN; CELL STRAIN HEK293; GENE EXPRESSION REGULATION; GLYCOSYLATION; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; MOUSE; NEURITE; NEWBORN; PARKINSON DISEASE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PSEUDOPODIUM; TRANSGENIC MOUSE; TUMOR CELL LINE;

ANIMALS; ANIMALS, NEWBORN; BRAIN; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOSYLATION; HEK293 CELLS; HUMANS; MICE; MICE, TRANSGENIC; NEURITES; PARKINSON DISEASE; PSEUDOPODIA; SODIUM CHANNELS;

MUS; MUS MUSCULUS;

EID: 84863769126     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.3684     Document Type: Article

References (40)

1. Brackenbury WJ, Davis TH, Chen C, et al. Voltage-gated Na+ channel beta1 subunit-mediated neurite outgrowth requires Fyn kinase and contributes to postnatal CNS development in vivo. J Neurosci. 2008; 28: 3246-56.
2. Isom LL, Ragsdale DS, De Jongh KS, et al. Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif. Cell. 1995; 83:433-42.
3. Kim DY, Ingamo LA, Carey BW, et al. Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration. J Biol Chem. 2005; 280:23251-61.
4. McEwen DP, Isom LL. Heterophilic interactions of sodium channel beta1 subunits with axonal and glial cell adhesion molecules. J Biol Chem. 2004; 279:52744-52.
5. Ratcliffe CF, Westenbroek RE, Curtis R, et al. Sodium channel beta1 and beta3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain. J Cell Biol. 2001; 154:427-34.
6. Miyazaki H, Oyama F, Wong HK, et al. BACE1 modulates filopodia-like protrusions induced by sodium channel beta4 subunit. Biochem Biophys Res Commun. 2007; 361:43-8.
7. Yu FH, Westenbroek RE, Silos-Santiago I, et al. Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2. J Neurosci. 2003; 23:7577-85.
8. Grieco TM, Malhotra JD, Chen C, et al. Open-channel block by the cytoplasmic tail of sodium channel beta4 as a mechanism for resurgent sodium current. Neuron. 2005; 45:233-44.
9. Bant JS, Raman IM. Control of transient, resurgent, and persistent current by open-channel block by Na channel beta4 in cultured cerebellar granule neurons. Proc Natl Acad Sci U S A. 2010; 107:12357-62.
10. Oyama F, Miyazaki H, Sakamoto N, et al. Sodium channel beta4 subunit: down-regulation and possible involvement in neuritic degeneration in Huntington's disease transgenic mice. J Neurochem. 2006; 98:518-29.
11. Roberts RH, Barchi RL. The voltage-sensitive sodium channel from rabbit skeletal muscle. Chemical characterization of subunits. J Biol Chem. 1987; 262:2298-303.
12. Schmidt JW, Catterall WA. Palmitylation, sulfation, and glycosylation of the alpha subunit of the sodium channel. Role of post-translational modifications in channel assembly. J Biol Chem. 1987; 262:13713-23.
13. Liu F, Zaidi T, Iqbal K, et al. Role of glycosylation in hyperphosphorylation of tau in Alzheimer's disease. FEBS Lett. 2002; 512:101-6.
14. Saez-Valero J, Fodero LR, Sjogren M, Andreasen N, et al. Glycosylation of acetylcholinesterase and butyrylcholinesterase changes as a function of the duration of Alzheimer's disease. J Neurosci Res. 2003; 72:520-6.
15. Silveyra MX, Cuadrado-Corrales N, Marcos A, et al. Altered glycosylation of acetylcholinesterase in Creutzfeldt-Jakob disease. J Neurochem. 2006; 96:97-104.
16. Spillantini MG, Schmidt ML, Lee VM, et al. Alpha-synuclein in Lewy bodies. Nature. 1997; 388:839-40.
17. Licker V, Kovaei E, Hochstrasser DF, et al. Proteomics in human Parkinson's disease research. J Proteomics. 2009; 73:10-29.
18. Farrer M, Chan P, Chen R, Tan L, et al. Lewy bodies and parkinsonism in families with parkin mutations. Ann Neurol. 2001; 50:293-300.
19. Shimura H, et al. Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science. 2001; 293:263-9.
20. Hwang H, Zhang J, Chung KA, et al. Glycoproteomics in neurodegenerative diseases. Mass Spectrom Rev. 2009; 29:79-125.
21. Giasson BI, Duda JE, Quinn SM, et al. Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron. 2002; 34:521-33.
22. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T) Method. Methods. 2001; 25:402-8.
23. Tyrrell L, Renganathan M, Dib-hajj SD, Waxman SG, et al. Glycosylation alters steady-state inactivation of sodium channel Nav1.9/NaN in dorsal root ganglion neurons and is developmentally regulated. J Neurosci. 2001; 21:9629-37.
24. Wong HK, Sakurai T, Oyama F, Kaneko K, et al. beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase. J Biol Chem. 2005; 280:23009-17.
25. Johnson D, Montpetie ML, Stocker PJ, Bennett ES, et al. The sialic acid component of the beta1 subunit modulates voltage-gated sodium channel function. J Biol Chem. 2004; 279:44303-10.
26. Johnson D, Bennett ES. Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating. J Biol Chem. 2006; 281:25875-81.
27. Yamamoto M, Kondo I, Ogawa N, Asanuma M, et al. Genetic association between susceptibility to Parkinson's disease and alpha1-antichymotrypsin polymorphism. Brain Res. 1997; 759:153-5.
28. Munoz E, Obach V, Oliva R, et al. Alpha1-antichymotrypsin gene polymorphism and susceptibility to Parkinson's disease. Neurology. 1999; 52:297-301.
29. Barchi RL, Cohen SA, and Murphy LE. Purification from rat sarcolemma of the saxitoxin-binding component of the excitable membrane sodium channel. Proc Natl Acad Sci U S A. 1980; 77:1306-10.
30. Vaughn DE, Bjorkman PJ. The (Greek) key to structures of neural adhesion molecules. Neuron. 1996; 16:261-73.
31. Kaczmarek LK. Non-conducting functions of voltage-gated ion channels. Nat Rev Neurosci. 2006; 7:761-71.
32. Yuste R, Bonhoeffer T. Genesis of dendritic spines: insights from ultrastructural and imaging studies. Nat Rev Neurosci. 2004; 5:24-34.
33. Lanctot PM, Leclerc PC, Clement M, et al. Importance of N-glycosylation positioning for cell-surface expression, targeting, affinity and quality control of the human AT1 receptor. Biochem J. 2005; 390:367-76.
34. Drescher B, Witte T, Schmidt RE, et al. Glycosylation of FcgammaRIII in N163 as mechanism of regulating receptor affinity. Immunology. 2003; 110:335-40.
35. Niu L, Heaney ML, Vera JC, et al. High-affinity binding to the GM-CSF receptor requires intact N-glycosylation sites in the extracellular domain of the beta subunit. Blood. 2000; 95:3357-62.
36. Maginnis MS, Haley SA, Gee GV, et al. Role of N-linked glycosylation of the 5-HT2A receptor in JC virus infection. J Virol. 2010; 84:9677-84.
37. Yu W, Sun Y, Guo S, et al. The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons. Hum Mol Genet. 2011; 20:3227-40.
38. Helton TD, Otsuka T, Lee MC, et al. Pruning and loss of excitatory synapses by the parkin ubiquitin ligase. Proc Natl Acad Sci U S A. 2008; 105:19492-7.
39. Messner DJ, Catterall WA. The sodium channel from rat brain. Separation and characterization of subunits. J Biol Chem. 1985; 260:10597-604.
40. Davis TH, Chen C, Isom LL, et al. Sodium channel beta1 subunits promote neurite outgrowth in cerebellar granule neurons. J Biol Chem. 2004; 279:51424-32.