Functional differences exist between TNFα promoters encoding the common -237g SNP and the rarer HLA-b*5701-linked A variant

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Simpson, Peter D ^a   Moysi, Eirini ^a   Wicks, Kate ^b   Sudan, Kritika ^a   Rowland Jones, Sarah L ^a   McMichael, Andrew J ^a   Knight, Julian ^b   Gillespie, Geraldine M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HLA B ANTIGEN; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

3' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA POLYMORPHISM; EPIGENETICS; GENE EXPRESSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIABILITY; HAPLOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MONOCYTE; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; B-LYMPHOCYTES; BASE SEQUENCE; CELL LINE; DNA METHYLATION; EPIGENESIS, GENETIC; GENES, REPORTER; HAPLOTYPES; HIV INFECTIONS; HLA-B ANTIGENS; HOMOZYGOTE; HUMANS; LIPOPOLYSACCHARIDES; LUCIFERASES; LYMPHOCYTE ACTIVATION; MICE; MOLECULAR SEQUENCE DATA; MONOCYTES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RNA, MESSENGER; SOFTWARE; SOLUBILITY; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

HUMAN IMMUNODEFICIENCY VIRUS 1; MUS;

EID: 84863764740     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040100     Document Type: Article

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