Corneal replication is an interferon response-independent bottleneck for virulence of herpes simplex virus 1 in the absence of virion host shutoff

Journal of Virology

Volumn 86, Issue 14, 2012, Pages 7692-7695

  Pasieka, Tracy Jo ^a   Menachery, Vineet D ^a   Rosato, Pamela C ^b   Leib, David A ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; BONE MARROW DERIVED DENDRITIC CELL; BRAIN INFECTION; CONTROLLED STUDY; CORNEA; CYTOKINE RESPONSE; DENDRITIC CELL; EYE INFECTION; GENE DELETION; HERPES SIMPLEX VIRUS 1; IN VIVO STUDY; INFECTION SENSITIVITY; KNOCKOUT MOUSE; MICROBIOLOGICAL PARAMETERS; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; VIRAL GENETICS; VIRION HOST SHUTOFF; VIROGENESIS; VIRUS INFECTION; VIRUS LOAD; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE; WILD TYPE;

ANIMALS; BONE MARROW CELLS; CORNEA; DENDRITIC CELLS; HERPESVIRUS 1, HUMAN; INTERFERON TYPE I; INTERFERON-GAMMA; KERATITIS, HERPETIC; MICE; MICE, TRANSGENIC; RIBONUCLEASES; VIRAL PROTEINS; VIRUS REPLICATION;

HUMAN HERPESVIRUS 1; MUS; SIMPLEXVIRUS;

EID: 84863754974     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00761-12     Document Type: Article

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