Chitosan/PLA nanoparticles as a novel carrier for the delivery of anthraquinone: Synthesis, characterization and in vitro cytotoxicity evaluation

Colloids and Surfaces B: Biointerfaces

Volumn 101, Issue , 2013, Pages 126-134

  Jeevitha, D ^a   Amarnath, Kanchana ^a  

^a SATHYABAMA UNIVERSITY   (India)

Author keywords

Anthraquinone; Cell cycle; Chitosan; HepG2 cells; Mitochondrial membrane potential; Nanocarriers; Necrosis; PLA

Indexed keywords

ANTHRAQUINONE; CELL CYCLE; HEPG2 CELLS; MITOCHONDRIAL MEMBRANE POTENTIAL; NANOCARRIERS; NECROSIS; PLA;

AROMATIC COMPOUNDS; CELL DEATH; CELL MEMBRANES; CHARACTERIZATION; CHITOSAN; CYTOTOXICITY; DRUG PRODUCTS; KETONES; LACTIC ACID; MAGNESIUM PRINTING PLATES; MEDICAL APPLICATIONS; SYNTHESIS (CHEMICAL);

NANOPARTICLES;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTHRAQUINONE; CHITOSAN; LIPOCORTIN 5; NANOPARTICLE; POLYLACTIC ACID; REACTIVE OXYGEN METABOLITE;

AGAR GEL ELECTROPHORESIS; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; AQUEOUS SOLUTION; ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DIPLOIDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; EVALUATION RESEARCH; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; PARTICLE SIZE; PH; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; STRUCTURE ANALYSIS; SUSTAINED RELEASE FORMULATION; TRANSMISSION ELECTRON MICROSCOPY;

ANNEXIN A5; ANTHRAQUINONES; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHITOSAN; DNA FRAGMENTATION; DNA, NEOPLASM; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; ELECTROPHORESIS, AGAR GEL; HUMANS; LACTIC ACID; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; NECROSIS; PARTICLE SIZE; POLYMERS; TETRAZOLIUM SALTS; THIAZOLES;

EID: 84863747411     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2012.06.019     Document Type: Article

References (45)

1. Gow-Chin Y., Pin-Der D., Da-Yon C. Food Chem. 2000, 70:437.
2. Ko J.K., Leung W.C., Ho W.K., Chiu P. Eur. J. Pharmacol. 2007, 559:1.
3. Hou Z., Lambert J.D., Chin K.V., Yang C.S. Mutat. Res. 2004, 555:3.
4. Clark G.B., Thompson G., Roux S.J. Curr. Sci. 2001, 80:170.
5. Lin H.L., Yang J.S., Yang J.H., Fan S.S., Chang W.C., Li Y.C., Chung J.G. Neurochem. Res. 2006, 31:383.
6. Sparreboom A., Cox M.C., Acharya M.R., Figg W.D. J. Clin. Oncol. 2004, 22:2489.
7. Sendelbach L.E. Toxicology 1989, 57:227.
8. Norbert O., Imre B., Zoltan S., Bela D. Dyes and Pigments 2008, 77:249.
9. Robert H.C., Yanjun Z., Navindra P., Seeram, Muraleedharan G.N. Life Sci. 2004, 74:1791.
10. Huang Q., Lu G., Shen H.M., Chung M.C., Ong C.N. Med. Res. Rev. 2007, 27:609.
11. Castiglione S., Fanciulli M., Bruno T. Anticancer Drugs 1993, 4:407.
12. Jinghua D., Yangde Z., Shiwei H., Yuxiang C., Bo L. Int. J. Pharm. 2010, 400:211.
13. Jin L., Feng L., Yong F., Wenjian Y., Xinxin A. Colloids Surf. B 2011, 82:297.
14. Geng L., Yonglong Z., Qing M., Mozhen W., Yue'e F. Carbohydr. Polym. 2008, 72:60.
15. Qi L.F., Xu Z.R., Jiang X., Hu C.H., Zou X.F. Carbohydr. Res. 2004, 339:2693.
16. Qi L.F., Xu Z.R., Jiang X., Li Y., Wang M.Q. Bioorg. Med. Chem. Lett. 2005, 15:1397.
17. Sanoj R.N., Muthunarayanan M., Muthuchelian K., Chennazhi K.P., Shanti V.N. Carbohydr. Polym. 2011, 84:407.
18. Yong H., Xiqun J., Yin D., Haixiong G., Yuyan Y., Changzheng Y. Biomaterials 2002, 23:3193.
19. Anitha A., Divya R.V.V., Krishna R., Sreeja V., Selvamurugan N. Carbohydr. Polym. 2009, 78:672.
20. Tzong-Ming W., Cheng-Yang W. Polym. Degrad. Stab. 2006, 91:2198.
21. Yan S., Changsheng L., Yuan Y., Xinyi T., Fan Y., Xiaoqian S. Biomaterials 2009, 30:2340.
22. Rahul M.R., Amol V.J., Douglas E.H. Prog. Polym. Sci. 2010, 35:338.
23. Xu-Bo Y., Yan-Bo Y., Wei J., Jie L., En-Jiang T. Int. J. Pharm. 2008, 349:241.
24. Nagarwal R.C., Singh P.N., Kant S., Maiti P., Pandit J.K. J. Biomed. Nanotechnol. 2010, 6:648.
25. Chandy T., Das G.S., Rao G.H. J. Microencapsul. 2000, 5:625.
26. Thuy T.T.N., Ok H.C., Jun S.P. Carbohydr. Polym. 2011, 86:1799.
27. Vauthier Adv. Drug Deliv. Rev. 2003, 55:519.
28. Cho K., Wang X., Nie S., Chen Z., Shin D.M. Clin. Cancer Res. 2008, 14:1310.
29. El-Ansary A., Al-Daihan S. J. Toxicol. 2009, 754.
30. Murali M.Y., Brij K.G., Meena J., Subhash C.C. J. Colloid Interface Sci. 2010, 351:19.
31. Qin T., Chuang-Nian Z., Xiu-Hua W., Wei W., Wei H. Biomaterials 2010, 31:4748.
32. Xufeng N., Qingling F., Mingbo W., Xiaodong G., Qixin Z. Polym. Degrad. Stab. 2009, 94:176.
33. Lemasters J.J., Qian T., Bradham C.A., Brenner D.A., Cascio W.E., Trost L.C., Nishimura Y., Nieminen A.L., Herman B. J. Bioenerg. Biomembr. 1999, 31:305.
34. Gerl R., Vaux D.L. Carcinogenesis 2005, 26:263.
35. Ward T.H., Cummings J., Dean E., Greystoke A., Hou J.M., Backen A., Ranson M., Dive C. Br. J. Cancer 2008, 99:841.
36. Green D.R., Reed J.C. Science (New York, N.Y.) 1998, 281:1309.
37. Nesslany F., Simar-Meintieres S., Ficheux H., Marzin D. Mutat. Res. 2009, 678:13.
38. Zhao Y., Cao J., Ma H., Liu J.W. Cancer Lett. 1997, 121:163.
39. Kono T., Watanabe M., Koyama K., Kishimoto T., Fukushima S., Sugimura T., Wakabayashi K. Cancer Lett. 1999, 137:75.
40. Kok Y.J., Swe M., Sit K.H. Necrosis has orderly DNA fragmentations. Biochem. Biophys. Res. Commun. 2002, 294:934.
41. Mueller S.O., Lutz W.K., Stopper H. Mutat. Res. 1998, 414:125.
42. Yan B., Wang H., Li F., Li C.Y. Br. J. Cancer 2006, 95:1696.
43. Pietenpol J.A., Stewart Z.A. Toxicology 2002, 182:475.
44. Innocente S.A., Abrahamson J.L., Cogswell J.P., Lee J.M. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:2147.
45. Sa G., Das T. Cell Div. 2008, 3:3.