GM-CSF priming drives bone marrow-derived macrophages to a pro-inflammatory pattern and downmodulates PGE2 in response to TLR2 ligands

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Sorgi, Carlos Arterio ^a   Rose, Stephanie ^b,c   Court, Nathalie ^b,c   Carlos, Daniela ^a   Paula Silva, Francisco Wanderley Garcia ^a   Assis, Patricia Aparecida ^a   Frantz, Fabiani Gai ^a   Ryffel, Bernhard ^b,c   Quesniaux, Valerie ^b,c   Faccioli, Lúcia Helena ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b CNRS   (France)

^c UNIVERSITÉ D'ORLÉANS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUKOTRIENE B4; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; NITRIC OXIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN E SYNTHASE; PROSTAGLANDIN E2; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; BONE MARROW DERIVED MACROPHAGE; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CONTROLLED STUDY; DOWN REGULATION; FATTY ACID SYNTHESIS; IMMUNOMODULATION; IMMUNOSTIMULATION; INNATE IMMUNITY; MACROPHAGE; MACROPHAGE FUNCTION; MEDIATOR RELEASE; MOUSE; NONHUMAN; PROTEIN LOCALIZATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BACTERIA; DINOPROSTONE; DOWN-REGULATION; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INFLAMMATION; INTERFERON-GAMMA; INTERLEUKIN-10; LEUKOTRIENE B4; LIGANDS; LIPIDS; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; NITRIC OXIDE; PPAR GAMMA; PROTEIN TRANSPORT; RNA, MESSENGER; TOLL-LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84863737019     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040523     Document Type: Article

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