Circadian variation in ghrelin and certain stress hormones in crib-biting horses

Veterinary Journal

Volumn 193, Issue 1, 2012, Pages 97-102

  Hemmann, Karin ^a   Raekallio, Marja ^a   Kanerva, Kira ^a   Hänninen, Laura ^a   Pastell, Matti ^b   Palviainen, Mari ^a   Vainio, Outi ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b Department of Production Animal Medicine ^*  (Finland)

Author keywords

Circadian rhythm; Cortisol; Crib biting; Equine; Ghrelin

Indexed keywords

BETA ENDORPHIN; CORTICOTROPIN; GHRELIN; HYDROCORTISONE;

ARTICLE; CHRONIC STRESS; CIRCADIAN RHYTHM; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; CRIB BITING; FEMALE; GHRELIN BLOOD LEVEL; HORMONE BLOOD LEVEL; HORSE; HYDROCORTISONE BLOOD LEVEL; MALE; NONHUMAN; REINFORCEMENT; STEREOTYPY;

ANIMALS; CIRCADIAN RHYTHM; FEMALE; GHRELIN; HORSES; HYDROCORTISONE; MALE; PRO-OPIOMELANOCORTIN; STEREOTYPED BEHAVIOR; STRESS, PHYSIOLOGICAL;

EQUIDAE;

EID: 84863717648     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2011.09.027     Document Type: Article

References (60)

1. 3 receptors are involved in the protective effect of ghrelin against HCl-induced gastric damage in rats. Pharmacology 2010, 86:259-266.
2. Bachmann I., Bernasconu P., Herrmann R., Weishaupt M.A., Stauffacher M. Behavioural and physiological responses to an acute stressor in crib-biting and control horses. Applied Animal Behavior Science 2003, 82:297-311.
3. Blum I.D., Patterson Z., Khazall R., Lamont E.W., Sleeman M.W., Horvath T.L., Abizaid A. Reduced anticipatory locomotor responses to scheduled meals in ghrelin receptor deficient mice. Neuroscience 2009, 164:351-359.
4. Brzozowski T., Konturek P.C., Konturek S.J., Kwiecień S., Drozdowicz D., Bielanski W., Pajdo R., Ptak A., Nikiforuk A., Pawlik W.W., Hahn E.G. Exogenous and endogenous ghrelin in gastroprotection against stress-induced gastric damage. Regulatory Peptides 2004, 120:39-51.
5. Cabib S., Giardino L., Calzá L., Zanni M., Mele A., Puglisi-Allegra S. Stress promotes major changes in dopamine receptor densities within the mesoaccumbens and nigro-striatal systems. Neuroscience 1998, 84:193-200.
6. Clegg H.A., Buckley P., Friend M.A., McGreevy P.D. The ethological and physiological characteristics of cribbing and weaving horses. Applied Animal Behavior Science 2008, 109:68-76.
7. Cooper J.J., Albentosa M.J. Behavioural adaptation in the domestic horse: Potential role of apparently abnormal responses including stereotypic behaviour. Livestock Production Science 2005, 92:177-182.
8. Cronin G.M., Wiepkema P.R., van Ree J.M. Endogenous opioids are involved in abnormal stereotyped behaviours of tethered sows. Neuropeptides 1985, 6:527-553.
9. Cummings D.E., Purnell J.Q., Frayo R.S., Schmidova K., Wisse B.E., Weigle D.S. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 2001, 50:1714-1719.
10. Czeisler C.A., Klerman E.B. Circadian and sleep-dependent regulation of hormone release in humans. Recent Progress in Hormone Research 1999, 54:97-132.
11. de Jong I.C., Prelle I.T., van de Burgwal J.A., Lambooij E., Korte S.M., Blokhuis H.J., Koolhaas J.M. Effects of environmental enrichment on behavioral responses to novelty, learning, and memory, and the circadian rhythm in cortisol in growing pigs. Physiology and Behavior 2000, 68:571-578.
12. Disse E., Bussier A.L., Deblon N., Pflugger P.T., Tschöp M.H., Laville M., Rohner-Jeanrenaud F. Systemic ghrelin and reward: Effect of cholinergic blockade. Physiology and Behavior 2011, 102:481-484.
13. Dodman N.H., Shuster L., Court M.H., Dixon R. Investigation into the use of narcotic antagonists in the treatment of a stereotypic behavior pattern (crib-biting) in the horse. American Journal of Veterinary Research 1987, 48:311-319.
14. Egecioglu E., Jerlhag E., Salomé N., Skibicka K.P., Haage D., Bohlooly-Y M., Andersson D., Bjursell M., Perrissoud D., Engel J.A., Dickson S.L. Ghrelin increases intake of rewarding food in rodents. Addiction Biology 2010, 15:304-311.
15. Engel J.A., Fehlke C., Hulthe P., Hard E., Johannessen K., Snape B., Svensson L. Biochemical and behavioral evidence for an interaction between ethanol and calcium-channel antagonists. Alcohol and Alcoholism 1988, 23:A13-A113.
16. Evans J.W., Winget C.M., Pollak E.J. Rhythmic cortisol secretion in the equine: Analysis and physiological mechanisms. Biological Rhythm Research 1977, 8:111-121.
17. Ferrulli A., Leggio L., Abenavoli L., Farnetti S., Malandrino N., D'Angelo C., Vonghia A., Mirijello S., Cardone S., Leso V., Domenicali M., Caputo F., Bernardi M., Stefanini G.F., Capristo E., Gasbarrini G., Addolorato G. Ghrelin in alcohol-dependent patients and correlation with nutritional and craving. Digestive and Liver Disease 2006, 38:160.
18. Freire R., Clegg H.A., Buckley P., Friend M.A., McGreevy P.D. The effects of two different amounts of dietary grain on the digestibility of the diet and behaviour of intensively managed horses. Applied Animal Behavior Science 2009, 117:69-73.
19. Gillham S.B., Dodman N.H., Shuster L., Kream R., Rand W. The effect of diet on cribbing behaviour and plasma β-endorphin in horses. Applied Animal Behavior Science 1994, 41:147-153.
20. Gordon M.E., McKeever K.H. Diurnal variation of ghrelin, leptin, and adiponectin in Standardbred mares. Journal of Animal Science 2005, 83:2365-2371.
21. Gordon M.E., McKeever K.H., Betros C.L., Manso H.C. Plasma leptin, ghrelin and adiponectin concentrations in young fit racehorses versus mature unfit Standardbred. The Veterinary Journal 2007, 173:91-100.
22. Hamra J.G., Kamerling S.G., Wolfsheimer K.J., Bagwell C.A. Diurnal variation in plasma ir-beta-endorphin levels and experimental pain thresholds in the horse. Life Sciences 1993, 53:121-129.
23. Hausberger M., Gautier E., Biquand V., Lunel C., Jégo P. Could work be a source of behavioural disorders? A study in horses. PLoS ONE 2009, 4:e7625.
24. Heleski C.R., Shelle A.C., Nielsen B.D., Zanella A.J. Influence of housing on weanling horse behaviour and subsequent welfare. Applied Animal Behavior Science 2002, 78:291-302.
25. Hemmings A., McBride S.D., Hale C.E. Perseverative responding and the aetiology of equine oral stereotypy. Applied Animal Behavior Science 2007, 104:143-150.
26. Hothersall B., Nicol C. Role of diet and feeding in normal and stereotypic behaviors in horses. Veterinary Clinics of North America: Equine Practice 2009, 25:167-181.
27. Hänninen L., Løvendahl P., Pasillé A.M., Rushen J. The effect of floor type or relocation on calves' pulsatile growth hormone and cortisol secretion. Acta Agriculturae Scandinavica, Section A - Animal Science 2006, 56:99-108.
28. Irvine C.H.G., Alexander S.L. Factors affecting the circadian rhythm in plasma cortisol concentrations in the horse. Domestic Animal Endocrinology 1994, 11:227-238.
29. Janssens C.J.J.G., Helmond F.A., Wiegant V.M. The effect of chronic stress on plasma cortisol concentrations in cyclic female pigs depends on the time of day. Domestic Animal Endocrinology 1995, 12:167-177.
30. Jerlhag E., Egecioglu E., Dickson S.L., Andersson M., Svensson L., Engel J.A. Ghrelin stimulates locomotor activity and accumbal dopamine-overflow via central cholinergic systems in mice: Implications for its involvement in brain reward. Addiction Biology 2006, 11:45-54.
31. Johnson K.G., Tyrrell J., Rowe J.B., Pethick W. Behavioural changes in stabled horses given nontherapeutic levels of virginiamycin. Equine Veterinary Journal 1998, 30:139-143.
32. Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999, 402:656-660.
33. Korff S., Stein D.J., Harvey B.H. Stereotypic behaviour in the deer mouse: Pharmacological validation and relevance for obsessive compulsive disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry 2008, 32:348-355.
34. Kraus T., Schanze A., Gröschl M., Bayerlein K., Hillemacher T., Reulbach U., Kornhuber J., Bleich S. Ghrelin levels are increased in alcoholism. Alcoholism: Clinical and experimental Research 2005, 29:2154-2157.
35. Larsson M., Edqvist L.-E., Ekman L., Persson S. Plasma cortisol in the horse diurnal rhythm and effects of exogenous ACTH. Acta Veterinaria Scandinavica 1979, 20:16-24.
36. Lebelt D., Zanella A.J., Unshelm J. Physiological correlates associated with cribbing behaviour in horses: Changes in thermal threshold, heart rate, plasma beta-endorphin and serotonin. Equine Veterinary Journal Suppl. 1998, 27:21-27.
37. Mason G., Rushen J., Clubb R., Latham N., Vickey S. Motivation and Motivational Explanations for Stereotypies. Stereotypic Animal Behaviour: Fundamentals and Applications to Welfare 2006, CAB International, Wallingford, Oxon, pp. 12-13. Second Ed.
38. Masuda Y., Tanaka T., Inomata N., Ohnuma N., Tanaka S., Itoh Z., Hosoda H., Kojima M., Kangawa K. Ghrelin stimulates gastric acid secretion and motility in rats. Biochemical and Biophysical Research Communications 2000, 276:905-908.
39. McBride S.D., Cuddeford D. The putative welfare-reducing effects of preventing equine stereotypic behaviour. Animal Welfare 2001, 10:173-189.
40. McBride S.D., Hemmings A. Altered mesoaccumbens and nigro-striatal dopamine physiology is associated with stereotypy development in a non-rodent species. Behavioural Brain Research 2005, 159:113-118.
41. Medica P., Cravana C., Fazio E., Ferlazzo A. 24-hour endocrine profiles of quarter horses under resting conditions. Journal of Equine Veterinary Science 2011, 31:35-40.
42. Mills D.S., Alston R.D., Rogers V., Longford N.T. Factors associated with the prevalence of stereotypic behaviour amongst Thoroughbred horses passing through auctioneer sales. Applied Animal Behavior Science 2002, 78:115-124.
43. Moeller B.A., McCall C.A., Silverman S.J., McElhenney W.H. Estimation of saliva production in crib-biting and normal horses. Journal of Equine Veterinary Science 2008, 28:85-90.
44. Mormède P., Courvoisier H., Ramos A., Marissal-Arvy N., Ousova O., Désautés C., Duclos M., Chaouloff F., Moisan M.P. Molecular genetics approaches to investigate individual variation in behavioural and neuroendocrine stress responses. Psychoneuroendocrinology 2002, 27:563-583.
45. Murphy B.A. Chronobiology and the horse: Recent revelations and future directions. The Veterinary Journal 2010, 18:105-114.
46. Nagy K., Bodó G., Bárdos G., Harnos A., Kabai P. The effect of feeding stress-test on the behaviour and heart rate variability of control and crib-biting horses (with or without inhibition). Applied Animal Behaviour Science 2009, 121:140-147.
47. Nicholson W.E., Davis D.R., Sherrell B.J., Orth D.N. Rapid radioimmunoassay for corticotrophin in unextracted human plasma. Clinical Chemistry 1984, 30:259-265.
48. Nicol C.J., Davidson H.P.D., Harris P.A., Waters A.J., Wilson A.D. Study of crib-biting and gastric inflammation and ulceration in young horses. Veterinary Record 2002, 30:658-662.
49. Nicol C.J., Badnell-Waters A.J. Suckling behaviour in domestic foals and the development of abnormal oral behaviour. Animal Behaviour 2004, 70:21-29.
50. Nicol C.J., Badnell-Waters A.J., Bice R., Kelland A., Wilson A.D., Harris P.A. The effects of diet and weaning method on the behaviour of young horses. Applied Animal Behaviour Science 2005, 95:205-221.
51. Pell S.M., McGreevy P.D. A study of cortisol and beta-endorphin levels in stereotypic and normal Thoroughbreds. Applied Animal Behavior Science 1999, 64:81-90.
52. Saka E., Goodrich C., Harlan P., Madras B.K., Graybiel A.M. Repetitive behaviors in monkeys are linked to specific striatal activation patterns. The Journal of Neuroscience 2004, 24:7557-7565.
53. Sato T., Fukue Y., Teranishi H.Y., Kojima M. Molecular forms of hypothalamic ghrelin and its regulation by fasting and 2-deoxy-d-glucose administration. Endocrinology 2005, 146:2510-2516.
54. Sibilia V., Pagani F., Rindi G., Lattuada N., Rapetti D., De Luca V., Campanini N., Bulgarelli I., Locatelli V., Guidobono F., Netti C. Central ghrelin gastroprotection involves nitric oxide/prostaglandin cross-talk. British Journal of Pharmacology 2008, 154:688-697.
55. Sugino T., Hasegawa Y., Kikkawa Y., Yamaura J., Yamagishi M., Kurose Y., Kojima M., Kangawa K., Terashima Y. A transient ghrelin surge occurs just before feeding in a scheduled meal-fed sheep. Biochemical and Biophysical Research Communications 2002, 295:255-260.
56. Sugino T., Hasegawa Y., Kurose Y., Kojima M., Kangawa K., Terashima Y. Effects of ghrelin on food intake and neuroendocrine function in sheep. Animal Reproduction Science 2004, 183-194.
57. Toshinai K., Mondal M.S., Nakazato M., Date Y., Murakami N., Kojima M., Kangawa K., Matsukura S. Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration. Biochemical and Biophysical Research Communications 2001, 281:1220-1225.
58. Vecchiotti G.G., Galanti R. Evidence of heredity of cribbing, weaving and stall-walking in Thoroughbred horses. Livestock Production Science 1986, 14:91-95.
59. Visser E.K., Ellis A.D., Van Reenen C.G. The effect of two different housing conditions on the welfare of young horses stabled for the first time. Applied Animal Behaviour Science 2008, 114:521-533.
60. Waters A.J., Nicol C.J., French N.P. Factors influencing the development of stereotypic and redirected behaviours in young horses: Findings of a four year prospective epidemiological study. Equine Veterinary Journal 2002, 34:572-579.