Genetic modification of baculovirus expression vectors

Virologica Sinica

Volumn 27, Issue 2, 2012, Pages 71-82

  Li, Shu Fen ^a   Wang, Hua Lin ^a   Hu, Zhi Hong ^a   Deng, Fei ^a  

^a WUHAN INSTITUTE OF VIROLOGY   (China)

Author keywords

Baculovirus; Gene delivery; Promoters; Protein expression; Signal peptides

Indexed keywords

BETA GALACTOSIDASE; CATHEPSIN V; CHITINASE; CHITINASE A; HEAT SHOCK PROTEIN 70; INTERLEUKIN 11; INTERLEUKIN 13; INTERLEUKIN 4; MELITTIN; UNCLASSIFIED DRUG;

AUTOGRAPHA CALIFORNICA MULTICASPID NUCLEOPOLYHEDROVIRUS; BACULOVIRUS EXPRESSION SYSTEM; BETA GALACTOSIDASE GENE; BOMBYX MORI NUCLEAR POLYHEDROSIS VIRUS; DNA MODIFICATION; ENHANCER REGION; GENE; GENE CASSETTE; GENE DELETION; GENE VECTOR; GENETIC ENGINEERING AND GENE TECHNOLOGY; HUMAN; INSECT CELL; NONHUMAN; POLYHEDROSIS VIRUS; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SECRETION; PSEUDOTYPING; REVIEW; SURFACE DISPLAY; VIRAL GENE DELIVERY SYSTEM; VIRUS GENOME;

ANIMALS; BACULOVIRIDAE; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS;

HEXAPODA; MAMMALIA;

EID: 84863710481     PISSN: 16740769     EISSN: 1995820X     Source Type: Journal    
DOI: 10.1007/s12250-012-3236-y     Document Type: Review

References (83)

1. Airenne K J, Hiltunen M O, Turunen M P, et al. 2000. Baculovirus-mediated periadventitial gene transfer to rabbit carotid artery. Gene Ther, 7:1499-1504.
2. Allet B, Bernard A R, Hochmann A, et al. 1997. A bacterial signal peptide directs efficient secretion of eukaryotic proteins in the baculovirus expression system. Protein Expr Purif, 9:61-68. (Pubitemid 27335472)
3. Altmann F, Staudacher E, Wilson I B, et al. 1999. Insect cells as hosts for the expression of recombinant glycoproteins. Glycoconj J, 16:109-123. (Pubitemid 29472137)
4. Ayres M D, Howard S C, Kuzio J, et al. 1994. The complete DNA sequence of Autographa californica nuclear polyhedrosis virus. Virology, 202:586-605. (Pubitemid 24254872)
5. Barsoum J, Brown R, McKee M, et al. 1997. Efficient transduction of mammalian cells by a recombinant baculovirus having the vesicular stomatitis virus G glycoprotein. Hum Gene Ther, 8:2011-2018.
6. Berger I, Fitzgerald D J, Richmond T J. 2004. Baculovirus expression system for heterologous multiprotein complexes. Nat Biotechnol, 22:1583-1587. (Pubitemid 40039463)
7. Bertolotti-Ciarlet A, Ciarlet M, Crawford S E, et al. 2003. Immunogenicity and protective efficacy of rotavirus 2/6-virus-like particles produced by a dual baculovirus expression vector and administered intramuscularly, intranasally, or orally to mice. Vaccine, 21:3885-3900. (Pubitemid 37338216)
8. Boublik Y, Di Bonito P, Jones I M. 1995. Eukaryotic virus display: engineering the major surface glycoprotein of the Autographa californica nuclear polyhedrosis virus (AcNPV) for the presentation of foreign proteins on the virus surface. Biotechnology (N Y), 13:1079-1084.
9. Boyce F M, Bucher N L. 1996. Baculovirus-mediated gene transfer into mammalian cells. Proc Natl Acad Sci U S A, 93:2348-2352. (Pubitemid 26104353)
10. Bright R A, Carter D M, Daniluk S, et al. 2007. Influenza virus-like particles elicit broader immune responses than whole virion inactivated influenza virus or recombinant hemagglutinin. Vaccine, 25:3871-3878. (Pubitemid 46589748)
11. Carbonell L F, Klowden M J, Miller L K. 1985. Baculovirus-mediated expression of bacterial genes in dipteran and mammalian cells. J Virol, 56:153-160. (Pubitemid 16256867)
12. Carbonell L F, Miller L K. 1987. Baculovirus interaction with nontarget organisms: a virus-borne reporter gene is not expressed in two mammalian cell lines. Appl Environ Microbiol, 53:1412-1417. (Pubitemid 17116731)
13. Chen Y, Yao B, Zhu Z, et al. 2004. A constitutive super-enhancer: homologous region 3 of Bombyx mori nucleopolyhedrovirus. Biochem Biophys Res Commun, 318:1039-1044. (Pubitemid 38625880)
14. Chen Y J, Chen W S, Wu T Y. 2005. Development of a bi-cistronic baculovirus expression vector by the Rhopalosiphum padi virus 5' internal ribosome entry site. Biochem Biophys Res Commun, 335:616-623.
15. Cheshenko N, Krougliak N, Eisensmith R C, et al. 2001. A novel system for the production of fully deleted adenovirus vectors that does not require helper adenovirus. Gene Ther, 8:846-854. (Pubitemid 32577189)
16. Condreay J P, Witherspoon S M, Clay W C, et al. 1999. Transient and stable gene expression in mammalian cells transduced with a recombinant baculovirus vector. Proc Natl Acad Sci U S A, 96:127-132. (Pubitemid 29036064)
17. Ernst W, Schinko T, Spenger A, et al. 2006. Improving baculovirus transduction of mammalian cells by surface display of a RGD-motif. J Biotechnol, 126:237-240. (Pubitemid 44528773)
18. Fang M, Dai X, Theilmann D A. 2007. Autographa californica multiple nucleopolyhedrovirus EXON0 (ORF141) is required for efficient egress of nucleocapsids from the nucleus. J Virol, 81:9859-9869. (Pubitemid 350067689)
19. Furlong A M, Thomsen D R, Marotti K R, et al. 1988. Active human tissue plasminogen activator secreted from insect cells using a baculovirus vector. Biotechnol Appl Biochem, 10:454-464.
20. Futatsumori-Sugai M, Tsumoto K. 2010. Signal peptide design for improving recombinant protein secretion in the baculovirus expression vector system. Biochem Biophys Res Commun, 391:931-935.
21. Gao H, Wang Y, Li N, et al. 2007. Efficient gene delivery into mammalian cells mediated by a recombinant baculovirus containing a whispovirus ie1 promoter, a novel shuttle promoter between insect cells and mammalian cells. J Biotechnol, 131:138-143. (Pubitemid 47187507)
22. Ge J, Huang Y, Hu X, et al. 2007. A surface-modified baculovirus vector with improved gene delivery to B-lymphocytic cells. J Biotechnol, 129:367-372. (Pubitemid 46560169)
23. Ghosh S, Parvez M K, Banerjee K, et al. 2002. Baculovirus as mammalian cell expression vector for gene therapy: an emerging strategy. Mol Ther, 6:5-11. (Pubitemid 36124264)
24. Gomi S, Majima K, Maeda S. 1999. Sequence analysis of the genome of Bombyx mori nucleopolyhedrovirus. J Gen Virol, 80 ( Pt 5):1323-1337. (Pubitemid 29213821)
25. Granados R R, Federici B A. 1986. The biology of baculoviruses. Boca Raton: CRC Press.
26. Groner A, Granados R R, Burand J P. 1984. Interaction of Autographa californica nuclear polyhedrosis virus with two nonpermissive cell lines. Intervirology, 21:203-209. (Pubitemid 14111271)
27. Gronowski A M, Hilbert D M, Sheehan K C, et al. 1999. Baculovirus stimulates antiviral effects in mammalian cells. J Virol, 73:9944-9951.
28. Harrison R L, Summers M D. 1995. Mutations in the Autographa californica multinucleocapsid nuclear polyhedrosis virus 25 kDa protein gene result in reduced virion occlusion, altered intranuclear envelopment and enhanced virus production. J Gen Virol, 76 (Pt 6):1451-1459.
29. Hill-Perkins M S, Possee R D. 1990. A baculovirus expression vector derived from the basic protein promoter of Autographa californica nuclear polyhedrosis virus. J Gen Virol, 71 ( Pt 4):971-976. (Pubitemid 20132905)
30. Hitchman R B, Possee R D, Crombie A T, et al. 2010. Genetic modification of a baculovirus vector for increased expression in insect cells. Cell Biol Toxicol, 26:57-68.
31. Hitchman R B, Possee R D, Siaterli E, et al. 2010. Improved expression of secreted and membrane-targeted proteins in insect cells. Biotechnol Appl Biochem, 56:85-93.
32. Hiyoshi M, Kageshima A, Kato T, et al. 2007. Construction of a cysteine protease deficient Bombyx mori multiple nucleopolyhedrovirus bacmid and its application to improve expression of a fusion protein. J Virol Methods, 144:91-97. (Pubitemid 47095040)
33. Hofmann C, Sandig V, Jennings G, et al. 1995. Efficient gene transfer into human hepatocytes by baculovirus vectors. Proc Natl Acad Sci U S A, 92:10099-10103.
34. Hu Y C, Lin S Y, Chen G Y. 2011. Recent Patents on the Baculovirus Systems. Recent Pat Biotechnol. (Epub ahead of print)
35. Huser A, Rudolph M, Hofmann C. 2001. Incorporation of decay-accelerating factor into the baculovirus envelope generates complement-resistant gene transfer vectors. Nat Biotechnol, 19:451-455. (Pubitemid 32428288)
36. Ishiyama S, Ikeda M. 2010. High-level expression and improved folding of proteins by using the vp39 late promoter enhanced with homologous DNA regions. Biotechnol Lett, 32:1637-1647.
37. Jarvis D L, Finn E E. 1996. Modifying the insect cell N-glycosylation pathway with immediate early baculovirus expression vectors. Nat Biotechnol, 14:1288-1292. (Pubitemid 26332792)
38. Jarvis D L, Fleming J A, Kovacs G R, et al. 1990. Use of early baculovirus promoters for continuous expression and efficient processing of foreign gene products in stably transformed lepidopteran cells. Biotechnology (N Y), 8:950-955.
39. Jarvis D L, Summers M D. 1989. Glycosylation and secretion of human tissue plasminogen activator in recombinant baculovirus-infected insect cells. Mol Cell Biol, 9:214-223. (Pubitemid 19024793)
40. Jarvis D L, Summers M D, Garcia A, et al. 1993. Influence of different signal peptides and prosequences on expression and secretion of human tissue plasminogen activator in the baculovirus system. J Biol Chem, 268:16754-16762. (Pubitemid 23229991)
41. Kaba S A, Salcedo A M, Wafula P O, et al. 2004. Development of a chitinase and v-cathepsin negative bacmid for improved integrity of secreted recombinant proteins. J Virol Methods, 122:113-118. (Pubitemid 39370057)
42. Kaikkonen M U, Raty J K, Airenne K J, et al. 2006. Truncated vesicular stomatitis virus G protein improves baculovirus transduction efficiency in vitro and in vivo. Gene Ther, 13:304-312. (Pubitemid 43223099)
43. Keil G M, Klopfleisch C, Giesow K, et al. 2009. Novel vectors for simultaneous high-level dual protein expression in vertebrate and insect cells by recombinant baculoviruses. J Virol Methods, 160:132-137.
44. King L A, Kaur K, Mann S G, et al. 1991. Secretion of single-chain urokinase-type plasminogen activator from insect cells. Gene, 106:151-157.
45. Kost T A, Condreay J P. 1999. Recombinant baculoviruses as expression vectors for insect and mammalian cells. Curr Opin Biotechnol, 10:428-433. (Pubitemid 29457266)
46. Kost T A, Condreay J P, Jarvis D L. 2005. Baculovirus as versatile vectors for protein expression in insect and mammalian cells. Nat Biotechnol, 23:567-575. (Pubitemid 41724895)
47. Li Y, Yang Y, Wang S. 2005. Neuronal gene transfer by baculovirus-derived vectors accommodating a neuronespecific promoter. Exp Physiol, 90:39-44.
48. Lo H R, Chou C C, Wu T Y, et al. 2002. Novel baculovirus DNA elements strongly stimulate activities of exogenous and endogenous promoters. J Biol Chem, 277:5256-5264.
49. Luckow V A, Lee S C, Barry G F, et al. 1993. Efficient generation of infectious recombinant baculoviruses by site-specific transposon-mediated insertion of foreign genes into a baculovirus genome propagated in Escherichia coli. J Virol, 67:4566-4579. (Pubitemid 23215935)
50. Ma L, Tamarina N, Wang Y, et al. 2000. Baculovirusmediated gene transfer into pancreatic islet cells. Diabetes, 49:1986-1991.
51. Maeda S, Kawai T, Obinata M, et al. 1985. Production of human alpha-interferon in silkworm using a baculovirus vector. Nature, 315:592-594. (Pubitemid 15021200)
52. Mahmood K, Bright R A, Mytle N, et al. 2008. H5N1 VLP vaccine induced protection in ferrets against lethal challenge with highly pathogenic H5N1 influenza viruses. Vaccine, 26:5393-5399.
53. Matilainen H, Makela A R, Riikonen R, et al. 2006. RGD motifs on the surface of baculovirus enhance transduction of human lung carcinoma cells. J Biotechnol, 125:114-126. (Pubitemid 44066605)
54. Meyer T H, van Endert P M, Uebel S, et al. 1994. Functional expression and purification of the ABC transporter complex associated with antigen processing (TAP) in insect cells. FEBS Lett, 351:443-447.
55. Miller L K. 1993. Baculoviruses: high-level expression in insect cells. Curr Opin Genet Dev, 3:97-101. (Pubitemid 23079654)
56. Mottershead D, van der Linden I, von Bonsdorff C H, et al. 1997. Baculoviral display of the green fluorescent protein and rubella virus envelope proteins. Biochem Biophys Res Commun, 238:717-722. (Pubitemid 27472640)
57. Nakanishi T, Goto C, Kobayashi M, et al. 2010. Comparative studies of lepidopteran baculovirus-specific protein FP25K: development of a novel Bombyx mori nucleopolyhedrovirus-based vector with a modified fp25K gene. J Virol, 84:5191-5200.
58. Noad R J, Stewart M, Boyce M, et al. 2009. Multigene expression of protein complexes by iterative modification of genomic Bacmid DNA. BMC Mol Biol, 10:87.
59. Ojala K, Mottershead D G, Suokko A, et al. 2001. Specific binding of baculoviruses displaying gp64 fusion proteins to mammalian cells. Biochem Biophys Res Commun, 284:777-784. (Pubitemid 32924797)
60. Olczak M, Olczak T. 2006. Comparison of different signal peptides for protein secretion in nonlytic insect cell system. Anal Biochem, 359:45-53. (Pubitemid 44693523)
61. Pan Y, Zhao Q, Fang L, et al. 2009. Efficient gene delivery into mammalian cells by recombinant baculovirus containing a hybrid cytomegalovirus promoter/Semliki Forest virus replicon. J Gene Med, 11:1030-1038.
62. Park E Y, Kageshima A, Kwon M S, et al. 2007. Enhanced production of secretory beta1, 3-N-acetylglucosaminyltransferase 2 fusion protein into hemolymph of Bombyx mori larvae using recombinant BmNPV bacmid integrated signal sequence. J Biotechnol, 129:681-688. (Pubitemid 46590448)
63. Park S W, Lee H K, Kim T G, et al. 2001. Hepatocytespecific gene expression by baculovirus pseudotyped with vesicular stomatitis virus envelope glycoprotein. Biochem Biophys Res Commun, 289:444-450.
64. Pieroni L, Maione D, La Monica N. 2001. In vivo gene transfer in mouse skeletal muscle mediated by baculovirus vectors. Hum Gene Ther, 12:871-881. (Pubitemid 32681852)
65. Possee R D, Thomas C J, King L A. 1999. The use of baculovirus vectors for the production of membrane proteins in insect cells. Biochem Soc Trans, 27:928-932. (Pubitemid 30032155)
66. Poul M A, Cerutti M, Chaabihi H, et al. 1995. Cassette baculovirus vectors for the production of chimeric, humanized, or human antibodies in insect cells. Eur J Immunol, 25:2005-2009.
67. Rasmussen L, Battles J K, Ennis W H, et al. 1990. Characterization of virus-like particles produced by a recombinant baculovirus containing the gag gene of the bovine immunodeficiency-like virus. Virology, 178:435-451. (Pubitemid 20349881)
68. Raty J K, Airenne K J, Marttila A T, et al. 2004. Enhanced gene delivery by avidin-displaying baculovirus. Mol Ther, 9:282-291. (Pubitemid 38256554)
69. Rohrmann G F. 1992. Baculovirus structural proteins. J Gen Virol, 73 ( Pt 4):749-761.
70. Sarkis C, Serguera C, Petres S, et al. 2000. Efficient transduction of neural cells in vitro and in vivo by a baculovirus-derived vector. Proc Natl Acad Sci U S A, 97:14638-14643. (Pubitemid 32016628)
71. Shoji I, Aizaki H, Tani H, et al. 1997. Efficient gene transfer into various mammalian cells, including non-hepatic cells, by baculovirus vectors. J Gen Virol, 78 ( Pt 10):2657-2664. (Pubitemid 27470010)
72. Smith G E, Summers M D, Fraser M J. 1983. Production of human beta interferon in insect cells infected with a baculovirus expression vector. Mol Cell Biol, 3:2156-2165.
73. Suzuki T, Kanaya T, Okazaki H, et al. 1997. Efficient protein production using a Bombyx mori nuclear polyhedrosis virus lacking the cysteine proteinase gene. J Gen Virol, 78 ( Pt 12):3073-3080. (Pubitemid 27511295)
74. Tessier D C, Thomas D Y, Khouri H E, et al. 1991. Enhanced secretion from insect cells of a foreign protein fused to the honeybee melittin signal peptide. Gene, 98:177-183.
75. Thiem S M, Miller L K. 1990. Differential gene expression mediated by late, very late and hybrid baculovirus promoters. Gene, 91:87-94. (Pubitemid 20293239)
76. Thomas C J, Brown H L, Hawes C R, et al. 1998. Localization of a baculovirus-induced chitinase in the insect cell endoplasmic reticulum. J Virol, 72:10207-10212. (Pubitemid 28520892)
77. Tiwari P, Saini S, Upmanyu S, et al. 2010. Enhanced expression of recombinant proteins utilizing a modified baculovirus expression vector. Mol Biotechnol, 46:80-89.
78. Tjia S T, zu Altenschildesche G M, Doerfler W. 1983. Autographa californica nuclear polyhedrosis virus (AcNPV) DNA does not persist in mass cultures of mammalian cells. Virology, 125:107-117. (Pubitemid 13149567)
79. Tomiya N, Betenbaugh M J, Lee Y C. 2003. Humanization of lepidopteran insect-cell-produced glycoproteins. Acc Chem Res, 36:613-620.
80. van Oers M M, Thomas A A, Moormann R J, et al. 2001. Secretory pathway limits the enhanced expression of classical swine fever virus E2 glycoprotein in insect cells. J Biotechnol, 86:31-38. (Pubitemid 32167011)
81. Venkaiah B, Viswanathan P, Habib S, et al. 2004. An additional copy of the homologous region (hr1) sequence in the Autographa californica multinucleocapsid polyhedrosis virus genome promotes hyperexpression of foreign genes. Biochemistry, 43:8143-8151. (Pubitemid 38808269)
82. Viswanathan P, Venkaiah B, Kumar M S, et al. 2003. The homologous region sequence (hr1) of Autographa californica multinucleocapsid polyhedrosis virus can enhance transcription from non-baculoviral promoters in mammalian cells. J Biol Chem, 278:52564-52571. (Pubitemid 38035853)
83. Vlak J M, Klinkenberg F A, Zaal K J, et al. 1988. Functional studies on the p10 gene of Autographa californica nuclear polyhedrosis virus using a recombinant expressing a p10-beta-galactosidase fusion gene. J Gen Virol, 69 ( Pt 4):765-776.