Continuous synthesis and purification by direct coupling of a flow reactor with simulated moving-bed chromatography

Angewandte Chemie - International Edition

Volumn 51, Issue 28, 2012, Pages 7028-7030

  O'Brien, Alexander G ^a   Horváth, Zoltán ^c   Lévesque, François ^a   Lee, Ju Weon ^c   Seidel Morgenstern, Andreas ^c   Seeberger, Peter H ^a,b  

^a MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c MAX PLANCK INSTITUTE FOR DYNAMICS OF COMPLEX TECHNICAL SYSTEMS   (Germany)

Author keywords

continuous synthesis; flow chemistry; nucleophilic aromatic substitution; purification; simulated moving bed chromatography

Indexed keywords

CONTINUOUS SYNTHESIS; CRUDE REACTION MIXTURES; DIRECT COUPLING; FLOW CHEMISTRY; FLOW REACTORS; MONOSUBSTITUTED PRODUCTS; MORPHOLINES; NUCLEOPHILIC AROMATIC SUBSTITUTION; SIMULATED MOVING BED CHROMATOGRAPHY;

AROMATIC COMPOUNDS; BYPRODUCTS; PURIFICATION; SYNTHESIS (CHEMICAL);

COLUMN CHROMATOGRAPHY;

EID: 84863708943     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201202795     Document Type: Article

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