메뉴 건너뛰기




Volumn 128, Issue 1-2, 2007, Pages 287-345

On the role of physics in the growth and pattern formation of multi-cellular systems: What can we learn from individual-cell based models?

Author keywords

Agent based models; Biomechanics; Blastulation; Cell populations; Early development; Gastrulation; Individual cell based models; Monolayer growth; Tumor growth

Indexed keywords


EID: 34249873259     PISSN: 00224715     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10955-007-9289-x     Document Type: Conference Paper
Times cited : (149)

References (146)
  • 1
    • 0000463651 scopus 로고    scopus 로고
    • The structural and mechanical complexity of cell-growth control
    • S. Huang and D. Ingber, The structural and mechanical complexity of cell-growth control. Nature Cell Biol. 1:E131 (1999).
    • (1999) Nature Cell Biol , vol.1
    • Huang, S.1    Ingber, D.2
  • 2
    • 0037736601 scopus 로고    scopus 로고
    • Mechanisms of pattern formation in development and evolution
    • I. Salazar-Ciudad, J. Jernvall, and S. A. Newman, Mechanisms of pattern formation in development and evolution. Development 130:2027 (2003).
    • (2003) Development , vol.130 , pp. 2027
    • Salazar-Ciudad, I.1    Jernvall, J.2    Newman, S.A.3
  • 3
    • 13944258082 scopus 로고    scopus 로고
    • EGFR autocrine signaling in a compliant interstitial space: Mechanotransduction from the outside in
    • D. J. Tschumperlin, EGFR autocrine signaling in a compliant interstitial space: Mechanotransduction from the outside in. Cell Cycle 3:996 (2004).
    • (2004) Cell Cycle , vol.3 , pp. 996
    • Tschumperlin, D.J.1
  • 4
    • 28844486408 scopus 로고    scopus 로고
    • Role of physical mechanisms in biological self-organization
    • A. Neagu, K. Jakab, R. Jamison, and G. Forgacs, Role of physical mechanisms in biological self-organization. Phys. Rev. Lett. 95:178104 (2005).
    • (2005) Phys. Rev. Lett , vol.95 , pp. 178104
    • Neagu, A.1    Jakab, K.2    Jamison, R.3    Forgacs, G.4
  • 8
    • 33646340966 scopus 로고    scopus 로고
    • Mechanical control of tissue morphogenesis during embryological development
    • D. Ingber, Mechanical control of tissue morphogenesis during embryological development. Int. J. Dev. Biol. 50:255 (2006).
    • (2006) Int. J. Dev. Biol , vol.50 , pp. 255
    • Ingber, D.1
  • 9
    • 23844500338 scopus 로고    scopus 로고
    • Mechanical control of tissue growth: Function follows form
    • D. Ingber, Mechanical control of tissue growth: Function follows form. Proc. Natl. Acad. Sci. (USA) 102:11571 (2005).
    • (2005) Proc. Natl. Acad. Sci. (USA) , vol.102 , pp. 11571
    • Ingber, D.1
  • 10
    • 0033637168 scopus 로고    scopus 로고
    • Role of cell division in branching morphogenesis and differentiation of the embryonic pancreas
    • L. D. Horb and J. M. Slack, Role of cell division in branching morphogenesis and differentiation of the embryonic pancreas. Int. J. Dev. Biol. 44:791 (2000).
    • (2000) Int. J. Dev. Biol , vol.44 , pp. 791
    • Horb, L.D.1    Slack, J.M.2
  • 11
    • 14744273475 scopus 로고    scopus 로고
    • Mechanical feedback as a possible regulator of tissue growth
    • B. Shraiman, Mechanical feedback as a possible regulator of tissue growth. Proc. Natl. Acad Sci. (USA) 102:3318 (2005).
    • (2005) Proc. Natl. Acad Sci. (USA) , vol.102 , pp. 3318
    • Shraiman, B.1
  • 14
    • 0035462048 scopus 로고    scopus 로고
    • The influence of growth-induced stress from the surrounding medium on the development of multicell spheroids
    • C. Chen, H. Byrne and J. King, The influence of growth-induced stress from the surrounding medium on the development of multicell spheroids, J. Math. Biol. 43:191 (2001).
    • (2001) J. Math. Biol , vol.43 , pp. 191
    • Chen, C.1    Byrne, H.2    King, J.3
  • 15
    • 0036708449 scopus 로고    scopus 로고
    • Calculation of forces at focal adhesions from elastic substrate data: The effect of localized force and the need for regularization
    • U. Schwarz, N. Balaban, D. Riveline, A. Bershadsky, B. Geiger, and S. Safran, Calculation of forces at focal adhesions from elastic substrate data: The effect of localized force and the need for regularization, Biophys. J. 83:1380 (2002).
    • (2002) Biophys. J , vol.83 , pp. 1380
    • Schwarz, U.1    Balaban, N.2    Riveline, D.3    Bershadsky, A.4    Geiger, B.5    Safran, S.6
  • 16
    • 0842281982 scopus 로고    scopus 로고
    • Modelling solid tumour growth using the theory of mixtures
    • H. Byrne and L. Prezziosi, Modelling solid tumour growth using the theory of mixtures, Math. Med. Biol. 20:341 (2003).
    • (2003) Math. Med. Biol , vol.20 , pp. 341
    • Byrne, H.1    Prezziosi, L.2
  • 17
    • 27144458382 scopus 로고    scopus 로고
    • Effect of poisson ratio on cellular structure formation
    • I. Bischofs and U. Schwarz, Effect of poisson ratio on cellular structure formation. Phys. Rev. Lett. 95:068102 (2005).
    • (2005) Phys. Rev. Lett , vol.95 , pp. 068102
    • Bischofs, I.1    Schwarz, U.2
  • 21
    • 0001455391 scopus 로고    scopus 로고
    • Single cell motion in aggregates of embryonic cells
    • J. Mombach and J. Glazier, Single cell motion in aggregates of embryonic cells. Phys. Rev. Lett. 76:3032 (1996).
    • (1996) Phys. Rev. Lett , vol.76 , pp. 3032
    • Mombach, J.1    Glazier, J.2
  • 24
    • 8644224901 scopus 로고    scopus 로고
    • An acoustic microscopy technique reveals hidden morphological defenses in daphnia
    • C. Laforsch, W. Ngwa, W. Grill, and R. Tollrian, An acoustic microscopy technique reveals hidden morphological defenses in daphnia. Proc. Natl. Acad. Sci. (USA) 101:15911 (2005).
    • (2005) Proc. Natl. Acad. Sci. (USA) , vol.101 , pp. 15911
    • Laforsch, C.1    Ngwa, W.2    Grill, W.3    Tollrian, R.4
  • 25
    • 0031682733 scopus 로고    scopus 로고
    • Measuring two-dimensional receptor-ligand binding kinetics by micropipette
    • S. Chesla, P. Selvaraj and C. Zhu, Measuring two-dimensional receptor-ligand binding kinetics by micropipette. Biophys. J. 75:1553 (1998).
    • (1998) Biophys. J , vol.75 , pp. 1553
    • Chesla, S.1    Selvaraj, P.2    Zhu, C.3
  • 27
    • 34249908396 scopus 로고    scopus 로고
    • Single-cell based mathematical models to the spatio-temporal pattern formation in multi-cellular systems
    • in press
    • J. Galle, G. Aust, G. Schaller, T. Beyer, and D. Drasdo, Single-cell based mathematical models to the spatio-temporal pattern formation in multi-cellular systems, Cytometry A, in press (2006).
    • (2006) Cytometry A
    • Galle, J.1    Aust, G.2    Schaller, G.3    Beyer, T.4    Drasdo, D.5
  • 28
    • 26844553603 scopus 로고    scopus 로고
    • Three-dimensional reconstruction and quantification of cervical carcinoma invasion fronts from histological serial sections
    • U. Braumann, J. Kuska, J. Einenkel, L. Horn, M. Loeffler, and M. Hoeckel, Three-dimensional reconstruction and quantification of cervical carcinoma invasion fronts from histological serial sections. IEEE Trans. Med. Imaging 24:1286 (2005).
    • (2005) IEEE Trans. Med. Imaging , vol.24 , pp. 1286
    • Braumann, U.1    Kuska, J.2    Einenkel, J.3    Horn, L.4    Loeffler, M.5    Hoeckel, M.6
  • 29
    • 0035470907 scopus 로고    scopus 로고
    • Traffic and related self-driven many particle systems
    • D. Helbing, Traffic and related self-driven many particle systems. Rev. Mod. Phys. 73:1067 (2001).
    • (2001) Rev. Mod. Phys , vol.73 , pp. 1067
    • Helbing, D.1
  • 30
    • 0001177693 scopus 로고
    • Monte-carlo approach to tissue-cell populations
    • D. Drasdo, R. Kree and J. McCaskill, Monte-carlo approach to tissue-cell populations. Phys. Rev. E 52:6635 (1995).
    • (1995) Phys. Rev. E , vol.52 , pp. 6635
    • Drasdo, D.1    Kree, R.2    McCaskill, J.3
  • 31
    • 0344063664 scopus 로고    scopus 로고
    • Cellular automata models of tumour development - a critical review
    • J. Moreira and A. Deutsch, Cellular automata models of tumour development - a critical review. Adv. Complex Syst. 5: 247 (2002).
    • (2002) Adv. Complex Syst , vol.5 , pp. 247
    • Moreira, J.1    Deutsch, A.2
  • 32
    • 34249894512 scopus 로고    scopus 로고
    • M. S. Alber, M. A. Kiskowski, J. A. Glazier, and Y. Jiang, On cellular automaton approaches to modeling biological cells. In Mathematical Systems Theory in Biology, Communication, and Finance, J. Rosenthal and D. S. Gilliam (eds.) (IMA 142, Springer-Verlag, New York, 2002), pp. 1-40.
    • M. S. Alber, M. A. Kiskowski, J. A. Glazier, and Y. Jiang, On cellular automaton approaches to modeling biological cells. In Mathematical Systems Theory in Biology, Communication, and Finance, J. Rosenthal and D. S. Gilliam (eds.) (IMA 142, Springer-Verlag, New York, 2002), pp. 1-40.
  • 33
    • 26944476134 scopus 로고    scopus 로고
    • On selected individual-based approaches to the dynamics of multicellular systems
    • J. L. W. Alt and M. Griebel eds, Birkhäuser
    • D. Drasdo, On selected individual-based approaches to the dynamics of multicellular systems. In Multiscale modeling, J. L. W. Alt and M. Griebel (eds.) (Birkhäuser, 2003).
    • (2003) Multiscale modeling
    • Drasdo, D.1
  • 34
    • 30344466626 scopus 로고    scopus 로고
    • T. Cickovski, C. Huang, R. Chaturvedi, T. Glimm, H. Hentschel, M. Alber, J. A. Glazier, S. A. Newman, and J. A. Izaguirre, A framework for three-dimensional simulation of morphogenesis. IEEE/ACM Trans. Comput. Biol. Bioinformatics 2:273 (2005).
    • T. Cickovski, C. Huang, R. Chaturvedi, T. Glimm, H. Hentschel, M. Alber, J. A. Glazier, S. A. Newman, and J. A. Izaguirre, A framework for three-dimensional simulation of morphogenesis. IEEE/ACM Trans. Comput. Biol. Bioinformatics 2:273 (2005).
  • 35
    • 17844408690 scopus 로고    scopus 로고
    • A cell-centered approach to developmental biology
    • R. Merks and J. Glazier, A cell-centered approach to developmental biology. Physica A 352:113 (2005).
    • (2005) Physica A , vol.352 , pp. 113
    • Merks, R.1    Glazier, J.2
  • 37
    • 0033548510 scopus 로고    scopus 로고
    • Evidence that hepatocyte growth factor abbrogates contact inhibition of mitosis in madin-darby canine kidney cell monolayers
    • D. Balkovetz, Evidence that hepatocyte growth factor abbrogates contact inhibition of mitosis in madin-darby canine kidney cell monolayers. Life Sci. 64:1393 (1999).
    • (1999) Life Sci , vol.64 , pp. 1393
    • Balkovetz, D.1
  • 38
    • 0033101647 scopus 로고    scopus 로고
    • Multicellular tumor spheroids: Intermediates between monolayer culture and in-vivo tumor
    • L. Kunz-Schughart, Multicellular tumor spheroids: Intermediates between monolayer culture and in-vivo tumor. Cell Biol. Int. 23:157 (1999).
    • (1999) Cell Biol. Int , vol.23 , pp. 157
    • Kunz-Schughart, L.1
  • 39
    • 25444482608 scopus 로고    scopus 로고
    • Retention of intrinsic stem cell hierarchies in carcinoma-derived cell lines
    • M. Locke, M. Heywood, S. Fawell, and I. Mackenzie, Retention of intrinsic stem cell hierarchies in carcinoma-derived cell lines. Cancer Res. 65:8944 (2005).
    • (2005) Cancer Res , vol.65 , pp. 8944
    • Locke, M.1    Heywood, M.2    Fawell, S.3    Mackenzie, I.4
  • 40
    • 0023093713 scopus 로고    scopus 로고
    • W. Mueller-Klieser, A review on cellular aggregates in cancer research. Cancer Res. Clin. Oncol. 113:101 (1987).
    • W. Mueller-Klieser, A review on cellular aggregates in cancer research. Cancer Res. Clin. Oncol. 113:101 (1987).
  • 41
    • 0024281372 scopus 로고
    • Cell and environment interactions in tumor microregions: The multicell spheroid model
    • R. Sutherland, Cell and environment interactions in tumor microregions: The multicell spheroid model. Science 240:177 (1988).
    • (1988) Science , vol.240 , pp. 177
    • Sutherland, R.1
  • 42
    • 0032970945 scopus 로고    scopus 로고
    • Three-dimensional spheroid model in tumor biology
    • M. Santini and G. Rainaldi, Three-dimensional spheroid model in tumor biology. Pathobiology 67:148 (1999).
    • (1999) Pathobiology , vol.67 , pp. 148
    • Santini, M.1    Rainaldi, G.2
  • 43
    • 34249884867 scopus 로고    scopus 로고
    • Sinauer Associates Inc, New York
    • S. Gilbert, Develoment (Sinauer Associates Inc., New York, 1997).
    • (1997) Develoment
    • Gilbert, S.1
  • 45
    • 0034080251 scopus 로고    scopus 로고
    • Gut instincts, thoughts on intestinal epithelial stem cells
    • C. Booth and C. Potten. Gut instincts, thoughts on intestinal epithelial stem cells. Clin. Invest. 105:1493 (2000).
    • (2000) Clin. Invest , vol.105 , pp. 1493
    • Booth, C.1    Potten, C.2
  • 46
    • 0025641727 scopus 로고
    • Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt
    • C. Potten and M. Loeffier, Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt. Development 110:1001 (1990).
    • (1990) Development , vol.110 , pp. 1001
    • Potten, C.1    Loeffier, M.2
  • 47
    • 0035423195 scopus 로고    scopus 로고
    • Individual-based models on growth and folding in one-layered tissues: Intestinal crypts and blastulation
    • D. Drasdo and M. Löffler, Individual-based models on growth and folding in one-layered tissues: Intestinal crypts and blastulation. Nonl. Anal. 47:245 (2001).
    • (2001) Nonl. Anal , vol.47 , pp. 245
    • Drasdo, D.1    Löffler, M.2
  • 48
    • 0032979426 scopus 로고    scopus 로고
    • Effects of keratinocyte growth factor in the squamous epithelium of the upper aero-digestive tract of normal and irradiated mice
    • C. Farrell, K. Rex, S. Kaufman, C. Dipalma, J. Chen, S. Scully and D. Layey, Effects of keratinocyte growth factor in the squamous epithelium of the upper aero-digestive tract of normal and irradiated mice. Int. J. Radiat. Biol. 75:609 (1999).
    • (1999) Int. J. Radiat. Biol , vol.75 , pp. 609
    • Farrell, C.1    Rex, K.2    Kaufman, S.3    Dipalma, C.4    Chen, J.5    Scully, S.6    Layey, D.7
  • 50
    • 34249907895 scopus 로고
    • Nutriention needs of mammalian cells in tissue culture
    • H. Eagle, Nutriention needs of mammalian cells in tissue culture. Science 122:43 (1955).
    • (1955) Science , vol.122 , pp. 43
    • Eagle, H.1
  • 51
    • 84883833623 scopus 로고
    • Clonal growth of mammalian cells in a chemically defined, synthetic medium
    • R. Ham, Clonal growth of mammalian cells in a chemically defined, synthetic medium. Proc. Natl. Acad. Sci. 53:288 (1965).
    • (1965) Proc. Natl. Acad. Sci , vol.53 , pp. 288
    • Ham, R.1
  • 52
    • 0017236014 scopus 로고
    • Replacement of serum by hormones permits growth of cells in defined medium
    • I. Hayashi and G. Sato, Replacement of serum by hormones permits growth of cells in defined medium. Nature 239:132 (1976).
    • (1976) Nature , vol.239 , pp. 132
    • Hayashi, I.1    Sato, G.2
  • 54
    • 0023027454 scopus 로고
    • Substrate adhesions in normal and transformed fibroblasts: Organization and regulation of cytoskeletal, membrane and extracellular matrix components at focal contacts
    • K. Burrige, Substrate adhesions in normal and transformed fibroblasts: Organization and regulation of cytoskeletal, membrane and extracellular matrix components at focal contacts. Cancer Review 4:18 (1986).
    • (1986) Cancer Review , vol.4 , pp. 18
    • Burrige, K.1
  • 56
    • 0029005577 scopus 로고
    • How do sea urchins invaginate? using biomechanics to distinguish between mechanisms of primary invagination
    • L. Davidson, M. Koehl, R. Keller, and G. Oster, How do sea urchins invaginate? using biomechanics to distinguish between mechanisms of primary invagination. Development 121:2005 (1995).
    • (1995) Development , vol.121 , pp. 2005
    • Davidson, L.1    Koehl, M.2    Keller, R.3    Oster, G.4
  • 57
    • 0033049359 scopus 로고    scopus 로고
    • Elasticity of normal and cancerous human bladder cells studied by scanning force microscopy
    • M. Lekka, P. Laidler, D. Gil, J. Lekki, Z. Stachura, and A. Z. Hrynkiewicz, Elasticity of normal and cancerous human bladder cells studied by scanning force microscopy. European Biophys. J. 28:312 (1999).
    • (1999) European Biophys. J , vol.28 , pp. 312
    • Lekka, M.1    Laidler, P.2    Gil, D.3    Lekki, J.4    Stachura, Z.5    Hrynkiewicz, A.Z.6
  • 58
    • 0031961856 scopus 로고    scopus 로고
    • Determining force dependence of two-dimensional receptorligand binding affinity by centrifugation
    • J. Piper, R. Swerlick and C. Zhu, Determining force dependence of two-dimensional receptorligand binding affinity by centrifugation. Biophys. J. 74:492 (1998).
    • (1998) Biophys. J , vol.74 , pp. 492
    • Piper, J.1    Swerlick, R.2    Zhu, C.3
  • 60
    • 35949007530 scopus 로고
    • Random walk and directed movement: Comparison between inert particles and self-organized molecular machines
    • M. Schienbein, K. Franke, and H. Gruler, Random walk and directed movement: Comparison between inert particles and self-organized molecular machines. Phys. Rev. E 49:5462 (1994).
    • (1994) Phys. Rev. E , vol.49 , pp. 5462
    • Schienbein, M.1    Franke, K.2    Gruler, H.3
  • 61
    • 0037461766 scopus 로고    scopus 로고
    • Mathematical oncology: Cancer summed up
    • R. A. Gatenby and P. K. Maini, Mathematical oncology: Cancer summed up. Nature 421:321 (2003).
    • (2003) Nature , vol.421 , pp. 321
    • Gatenby, R.A.1    Maini, P.K.2
  • 64
    • 0033558810 scopus 로고    scopus 로고
    • A gerneral equation for fitting contact area and friction vs. load measurements
    • R. Carpick, D. F. Ogletree, and M. Salmeron, A gerneral equation for fitting contact area and friction vs. load measurements. J. Colloid Interface Sci. 211:395 (1999).
    • (1999) J. Colloid Interface Sci , vol.211 , pp. 395
    • Carpick, R.1    Ogletree, D.F.2    Salmeron, M.3
  • 65
    • 34249901595 scopus 로고    scopus 로고
    • Y.-S. C. et al.: Johnson-kendall-roberts theory applied to living cells. Phys. Rev. Lett. 280:312 (1999).
    • Y.-S. C. et al.: Johnson-kendall-roberts theory applied to living cells. Phys. Rev. Lett. 280:312 (1999).
  • 66
    • 26944481103 scopus 로고    scopus 로고
    • A single-cell based model to tumor growth in-vitro: Monolayers and spheroids
    • D. Drasdo and S. Hoehme, A single-cell based model to tumor growth in-vitro: Monolayers and spheroids. Phys. Biol. 2:133 (2005).
    • (2005) Phys. Biol , vol.2 , pp. 133
    • Drasdo, D.1    Hoehme, S.2
  • 68
    • 0033778696 scopus 로고    scopus 로고
    • Modelling the interplay of generic and genetic mechanisms in cleavage, blastulation and gastrulation
    • D. Drasdo and G. Forgacs, Modelling the interplay of generic and genetic mechanisms in cleavage, blastulation and gastrulation. Dev. Dyn. 219:182 (2000).
    • (2000) Dev. Dyn , vol.219 , pp. 182
    • Drasdo, D.1    Forgacs, G.2
  • 69
    • 0037898943 scopus 로고    scopus 로고
    • Individual-based approaches to birth and death in avascular tumors
    • D. Drasdo and S. Höhme, Individual-based approaches to birth and death in avascular tumors. Math. and Comp. Modelling 37:1163 (2003).
    • (2003) Math. and Comp. Modelling , vol.37 , pp. 1163
    • Drasdo, D.1    Höhme, S.2
  • 73
    • 33845332311 scopus 로고    scopus 로고
    • Garland Science, New York and Oxford
    • R. Weinberg, The biology of cancer (Garland Science, New York and Oxford, 2007).
    • (2007) The biology of cancer
    • Weinberg, R.1
  • 74
    • 0034206088 scopus 로고    scopus 로고
    • Front propagation in heterogeneous media
    • J. Xin, Front propagation in heterogeneous media. SIAM Rev. 42:161 (2000).
    • (2000) SIAM Rev , vol.42 , pp. 161
    • Xin, J.1
  • 75
    • 0033752019 scopus 로고    scopus 로고
    • quantitativ model for differential motility of gliomas in gey and white matter
    • K. Swanson, E. Alvord, and J. Murray, quantitativ model for differential motility of gliomas in gey and white matter. Cell Prolif. 33:317 (2000).
    • (2000) Cell Prolif , vol.33 , pp. 317
    • Swanson, K.1    Alvord, E.2    Murray, J.3
  • 77
    • 11244250625 scopus 로고    scopus 로고
    • Modelling the effect of deregulated proliferation and apoptosis on the growth dynamics of epithelial cell populations in-vitro
    • J. Galle, M. Loeffler, and D. Drasdo, Modelling the effect of deregulated proliferation and apoptosis on the growth dynamics of epithelial cell populations in-vitro. Biophys. J. 88:62 (2005).
    • (2005) Biophys. J , vol.88 , pp. 62
    • Galle, J.1    Loeffler, M.2    Drasdo, D.3
  • 78
    • 25844463997 scopus 로고    scopus 로고
    • Multicellular tumor spheroid in an off-lattice voronoidelaunay cell model
    • G. Schaller and M. Meyer-Hermann, Multicellular tumor spheroid in an off-lattice voronoidelaunay cell model. Phys. Rev. E. 71:051910 (2005).
    • (2005) Phys. Rev. E , vol.71 , pp. 051910
    • Schaller, G.1    Meyer-Hermann, M.2
  • 79
    • 0031961856 scopus 로고    scopus 로고
    • Determining force dependence of two-dimensional receptorligand binding affinity by centrifugation
    • J. Piper, R. Swerlick, and C. Zhu, Determining force dependence of two-dimensional receptorligand binding affinity by centrifugation. Biophys. J. 74:492 (1998).
    • (1998) Biophys. J , vol.74 , pp. 492
    • Piper, J.1    Swerlick, R.2    Zhu, C.3
  • 81
  • 82
    • 0036549213 scopus 로고    scopus 로고
    • Cell density and n-cadherin interaction regulates cell proliferation in the sensory epithelia of the inner ear
    • M. Warchol, Cell density and n-cadherin interaction regulates cell proliferation in the sensory epithelia of the inner ear. J. Neurosci. 22:2607 (2002).
    • (2002) J. Neurosci , vol.22 , pp. 2607
    • Warchol, M.1
  • 83
    • 0034849664 scopus 로고    scopus 로고
    • Mammary epithelial cell-cycle progression via the α2β1-integrin
    • P. Klekotka, S. Santoro, A. Ho, S. Dowdy, and M. Zutter, Mammary epithelial cell-cycle progression via the α2β1-integrin. Am. J. Path. 159:983 (2001).
    • (2001) Am. J. Path , vol.159 , pp. 983
    • Klekotka, P.1    Santoro, S.2    Ho, A.3    Dowdy, S.4    Zutter, M.5
  • 85
    • 0036796781 scopus 로고    scopus 로고
    • Get a ligand, get a life: Integrins, signaling and cell survival
    • D. Stupack and D. Cheresh, Get a ligand, get a life: Integrins, signaling and cell survival. J. Cell Sci. 115:3729 (2002).
    • (2002) J. Cell Sci , vol.115 , pp. 3729
    • Stupack, D.1    Cheresh, D.2
  • 86
    • 0033598162 scopus 로고    scopus 로고
    • Exogenous expression of β-catenin regulates contact inhibition, anchorage-independent growth, anoikis and radiation-induced cell cycle arrest
    • K. Orford. C. Orford, and S. W. Byers, Exogenous expression of β-catenin regulates contact inhibition, anchorage-independent growth, anoikis and radiation-induced cell cycle arrest. J. Cell Biol. 146:855 (1999).
    • (1999) J. Cell Biol , vol.146 , pp. 855
    • Orford, K.1    Orford, C.2    Byers, S.W.3
  • 87
    • 0030712329 scopus 로고    scopus 로고
    • Oncogenic ki-ras but not oncogenic ha-ras blocks integrin? 1-chain maturation in colon epithelial cells
    • Z. Yan, M. Chen, M. Perucho, and E. Friedman, Oncogenic ki-ras but not oncogenic ha-ras blocks integrin? 1-chain maturation in colon epithelial cells. J. Biol. Chem. 272:2607 (1997).
    • (1997) J. Biol. Chem , vol.272 , pp. 2607
    • Yan, Z.1    Chen, M.2    Perucho, M.3    Friedman, E.4
  • 88
    • 0028999873 scopus 로고
    • bcl-2 overexpression inhibits cell death and promotes the morphogenesis, but not tumorigenesis of human mammary epithelial cells
    • P. Lu, Q. Lu, A. Rughetti, and J. Taylor-Papadimitriou, bcl-2 overexpression inhibits cell death and promotes the morphogenesis, but not tumorigenesis of human mammary epithelial cells. J. Cell Biol. 129:1363 (1995).
    • (1995) J. Cell Biol , vol.129 , pp. 1363
    • Lu, P.1    Lu, Q.2    Rughetti, A.3    Taylor-Papadimitriou, J.4
  • 90
    • 0033804913 scopus 로고    scopus 로고
    • Apoptosis, cell adhesion and the extracellular matrix in the three-dimensional growth of multicellular tumor spheroids
    • M. Santini, G. Rainaldi, and P. Indovina, Apoptosis, cell adhesion and the extracellular matrix in the three-dimensional growth of multicellular tumor spheroids. Crit. Rev. Oncology/Hematology 36:75 (2000).
    • (2000) Crit. Rev. Oncology/Hematology , vol.36 , pp. 75
    • Santini, M.1    Rainaldi, G.2    Indovina, P.3
  • 92
    • 0031026750 scopus 로고    scopus 로고
    • Cell-cell contact changes the dynamics of lamellar activity in nontransformed epitheliocytes but not in their ras-transformed descendants
    • N. Gloushankova, N. Alieva, M. Krendel, E. Bonder, H. Feder, J. Vasiliev, and I. Gelfand, Cell-cell contact changes the dynamics of lamellar activity in nontransformed epitheliocytes but not in their ras-transformed descendants. Proc. Natl. Acad. Sci. USA 94:879 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 879
    • Gloushankova, N.1    Alieva, N.2    Krendel, M.3    Bonder, E.4    Feder, H.5    Vasiliev, J.6    Gelfand, I.7
  • 94
    • 0035803323 scopus 로고    scopus 로고
    • Internal fluctuations effects on fisher waves
    • E. Moro, Internal fluctuations effects on fisher waves. Phys. Rev. Lett. 87:238303 (2001).
    • (2001) Phys. Rev. Lett , vol.87 , pp. 238303
    • Moro, E.1
  • 95
    • 0012575045 scopus 로고
    • Kinetic roughening phenomena, stochastic growth, directed polymers and all that
    • T. Halpin-Healy and Y. Zhang, Kinetic roughening phenomena, stochastic growth, directed polymers and all that. Phys. Rep. 254:215 (1995).
    • (1995) Phys. Rep , vol.254 , pp. 215
    • Halpin-Healy, T.1    Zhang, Y.2
  • 96
    • 34249893424 scopus 로고    scopus 로고
    • Classifying the expansion kinetics and critical surface dynamics of growing cell populations
    • 0610146 2006
    • M. Block, E. Schoell, and D. Drasdo, Classifying the expansion kinetics and critical surface dynamics of growing cell populations, Cond. mat. physics/0610146 (2006).
    • Cond. mat. physics
    • Block, M.1    Schoell, E.2    Drasdo, D.3
  • 97
    • 29144486760 scopus 로고    scopus 로고
    • Coarse graining in simulated cell populations
    • D. Drasdo, Coarse graining in simulated cell populations. Adv. Complex Syst. 8:319 (2005).
    • (2005) Adv. Complex Syst , vol.8 , pp. 319
    • Drasdo, D.1
  • 98
    • 0000021157 scopus 로고    scopus 로고
    • Generic dynamic scaling in kinetic roughening
    • J. Ramasco, J. Lopez, and M. Rodriguez, Generic dynamic scaling in kinetic roughening. Phys. Rev. Lett. 84:2199 (2000).
    • (2000) Phys. Rev. Lett , vol.84 , pp. 2199
    • Ramasco, J.1    Lopez, J.2    Rodriguez, M.3
  • 99
    • 0037941875 scopus 로고
    • Scaling of the active zone in the eden process on percolation networks and the ballistic deposition model
    • F. Family and T. Vicsek, Scaling of the active zone in the eden process on percolation networks and the ballistic deposition model. J. Phys. A: Math. Gen. 18:L75 (1985).
    • (1985) J. Phys. A: Math. Gen , vol.18
    • Family, F.1    Vicsek, T.2
  • 100
    • 17844379477 scopus 로고    scopus 로고
    • Comments on the article - the universal dynamics of tumor growth
    • J. Buceta and J. Galeano, Comments on the article - the universal dynamics of tumor growth. Biophys. J. 88:3734 (2005).
    • (2005) Biophys. J , vol.88 , pp. 3734
    • Buceta, J.1    Galeano, J.2
  • 101
    • 0037477627 scopus 로고    scopus 로고
    • Adhesion-independent mechanism for suppression of tumor cell invasion by e-cadherin
    • A. Wong and B. Gumbiner, Adhesion-independent mechanism for suppression of tumor cell invasion by e-cadherin. J. Cell Biol. 161:1191 (2003).
    • (2003) J. Cell Biol , vol.161 , pp. 1191
    • Wong, A.1    Gumbiner, B.2
  • 102
    • 1642282882 scopus 로고    scopus 로고
    • Prespecification and plasticity: Shifting mechanisms of cell migration
    • P. Friedl, Prespecification and plasticity: Shifting mechanisms of cell migration. Curr. Opin. Cell. Biol. 16:14 (2004).
    • (2004) Curr. Opin. Cell. Biol , vol.16 , pp. 14
    • Friedl, P.1
  • 103
    • 0022351061 scopus 로고
    • A reduction in the in situ rates of oxygen and glucose consumption of cells in emt6/ro spheroids during growthregulation of growth
    • J. Freyer and R. Sutherland, A reduction in the in situ rates of oxygen and glucose consumption of cells in emt6/ro spheroids during growthregulation of growth. J. Cell. Physiol. 124:516 (1985).
    • (1985) J. Cell. Physiol , vol.124 , pp. 516
    • Freyer, J.1    Sutherland, R.2
  • 104
    • 0022642722 scopus 로고
    • Regulation of growth saturation and development of necrosis in emt6/ro multicellular spheroids by the glucose and oxygene supply
    • J. Freyer and R. Sutherland, Regulation of growth saturation and development of necrosis in emt6/ro multicellular spheroids by the glucose and oxygene supply. Cancer Res. 46:3504 (1986).
    • (1986) Cancer Res , vol.46 , pp. 3504
    • Freyer, J.1    Sutherland, R.2
  • 105
    • 0023777948 scopus 로고
    • Glucose diffusivity in multicellular tumor spheroids
    • J. Casciari, S. Sotirchos, and R. Sutherland, Glucose diffusivity in multicellular tumor spheroids. Cancer Res. 48:3905 (1988).
    • (1988) Cancer Res , vol.48 , pp. 3905
    • Casciari, J.1    Sotirchos, S.2    Sutherland, R.3
  • 106
    • 0026568374 scopus 로고
    • Variations in tumor cell growth rates and metabolism with oxygen concentration, glucose concentration and extracellular ph
    • J. Casciari, S. Sotirchos, and R. Sutherland, Variations in tumor cell growth rates and metabolism with oxygen concentration, glucose concentration and extracellular ph. J. Cell. Physiol. 151:386 (1992).
    • (1992) J. Cell. Physiol , vol.151 , pp. 386
    • Casciari, J.1    Sotirchos, S.2    Sutherland, R.3
  • 108
    • 0033199022 scopus 로고    scopus 로고
    • Stochastic simulation of benign avascular tumor growth using the potts model
    • E. Stott, N. Britton, J. Glazier, and M. Zajac, Stochastic simulation of benign avascular tumor growth using the potts model. Math. Comput. Modelling 30:183 (1999).
    • (1999) Math. Comput. Modelling , vol.30 , pp. 183
    • Stott, E.1    Britton, N.2    Glazier, J.3    Zajac, M.4
  • 109
    • 1542344734 scopus 로고    scopus 로고
    • Modeling of self-organized avascular tumor growth with a hybrid cellular automaton
    • S. Dormann and A. Deutsch, Modeling of self-organized avascular tumor growth with a hybrid cellular automaton. Silica Biol. 2:0035 (2002).
    • (2002) Silica Biol , vol.2 , pp. 0035
    • Dormann, S.1    Deutsch, A.2
  • 110
    • 0015804548 scopus 로고
    • Self-regulation of growth in three dimensions
    • J. Folkman and M. Hochberg, Self-regulation of growth in three dimensions. J. Exp. Med 138:745 (1973).
    • (1973) J. Exp. Med , vol.138 , pp. 745
    • Folkman, J.1    Hochberg, M.2
  • 111
    • 0000825469 scopus 로고
    • Simulation of the differential adhesion driven rearrangement of biological cells
    • J. Glazier and F. Graner, Simulation of the differential adhesion driven rearrangement of biological cells. Phys. Rev. E 47:2128 (1993).
    • (1993) Phys. Rev. E , vol.47 , pp. 2128
    • Glazier, J.1    Graner, F.2
  • 112
    • 33750234189 scopus 로고    scopus 로고
    • Modeling multi-cellular systems using sub-cellular elements
    • T. Newman, Modeling multi-cellular systems using sub-cellular elements. Math. Biosciences Eng. 2:613 (2005).
    • (2005) Math. Biosciences Eng , vol.2 , pp. 613
    • Newman, T.1
  • 114
    • 0034180349 scopus 로고    scopus 로고
    • Buckling instabilities in one-layered growing tissues
    • D. Drasdo, Buckling instabilities in one-layered growing tissues. Phys. Rev. Lett. 84:4244 (2000).
    • (2000) Phys. Rev. Lett , vol.84 , pp. 4244
    • Drasdo, D.1
  • 115
    • 78149412083 scopus 로고
    • The mechanics of sea urchin development, studied by operative methods
    • S. Hörstadius, The mechanics of sea urchin development, studied by operative methods. Biol. Rev. 14:132 (1939).
    • (1939) Biol. Rev , vol.14 , pp. 132
    • Hörstadius, S.1
  • 116
    • 0000746599 scopus 로고    scopus 로고
    • K. Dan, Cytoembryology of echinoderms and amphibia. Int. Rev. Cytol 9:321 (1960).
    • K. Dan, Cytoembryology of echinoderms and amphibia. Int. Rev. Cytol 9:321 (1960).
  • 117
    • 0007590130 scopus 로고
    • An electron microscope study of the development of the blastula of the sea urchin embryo and its radial polarity
    • L. Wolpert and E. Mercer, An electron microscope study of the development of the blastula of the sea urchin embryo and its radial polarity. Exp. Cell Res. 30:280 (1963).
    • (1963) Exp. Cell Res , vol.30 , pp. 280
    • Wolpert, L.1    Mercer, E.2
  • 118
    • 0025080165 scopus 로고
    • Cell shape changes during gastrulation in drosophila
    • M. Leptin and B. Grunewald, Cell shape changes during gastrulation in drosophila. Development 110:73 (1990).
    • (1990) Development , vol.110 , pp. 73
    • Leptin, M.1    Grunewald, B.2
  • 120
    • 4544373286 scopus 로고    scopus 로고
    • How cellular movement determines the collective force generated by the dictyostelium discoideum slug
    • J. Dallon and H. Othmer, How cellular movement determines the collective force generated by the dictyostelium discoideum slug. J. theor. Biol. 231:203 (2004).
    • (2004) J. theor. Biol , vol.231 , pp. 203
    • Dallon, J.1    Othmer, H.2
  • 121
    • 0034641740 scopus 로고    scopus 로고
    • A model for individual and collective cell movement in dictyostelium discoideum
    • E. Palsson and H. Othmer, A model for individual and collective cell movement in dictyostelium discoideum. Proc. Natl. Acad. Sci. USA 12:10448 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.12 , pp. 10448
    • Palsson, E.1    Othmer, H.2
  • 122
    • 0025903537 scopus 로고
    • Drosophila gastrulation: Analysis of cell shape changes in living embryos by three-dimensional fluorescence mircroscopy
    • Z. Kam, J. Minden, D. Agard, J. Sedat, and M. Leptin, Drosophila gastrulation: Analysis of cell shape changes in living embryos by three-dimensional fluorescence mircroscopy. Development 112:365 (1991).
    • (1991) Development , vol.112 , pp. 365
    • Kam, Z.1    Minden, J.2    Agard, D.3    Sedat, J.4    Leptin, M.5
  • 123
    • 84982634996 scopus 로고
    • Fission of crypts in the small intestine of the irradiated mouse
    • A. Cairnie and B. Millen, Fission of crypts in the small intestine of the irradiated mouse. Cell Tissue Kinet. 8:89 (1975).
    • (1975) Cell Tissue Kinet , vol.8 , pp. 89
    • Cairnie, A.1    Millen, B.2
  • 124
    • 0028789246 scopus 로고
    • A morphological study on the histogenesis of human colorectal hyperplastic crypts
    • K. Araki, T. Ogata, M. Kobayashi, and R. Yatani, A morphological study on the histogenesis of human colorectal hyperplastic crypts. Gastroenterology 109:1468 (1995)
    • (1995) Gastroenterology , vol.109 , pp. 1468
    • Araki, K.1    Ogata, T.2    Kobayashi, M.3    Yatani, R.4
  • 125
    • 3242656567 scopus 로고    scopus 로고
    • Pinning of tumoral growth by enhancement of the immune response
    • A. Bru, S. Albertos, J. L. Garcia-Asenjo, and I. Bru, Pinning of tumoral growth by enhancement of the immune response. Phys. Rev. Lett. 92:238101 (2004).
    • (2004) Phys. Rev. Lett , vol.92 , pp. 238101
    • Bru, A.1    Albertos, S.2    Garcia-Asenjo, J.L.3    Bru, I.4
  • 126
    • 0025334830 scopus 로고
    • Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: Implications for therapy
    • Y. Boucher, L. Baxter, and R. Jain, Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: Implications for therapy. Cancer Res. 50:4478 (1990).
    • (1990) Cancer Res , vol.50 , pp. 4478
    • Boucher, Y.1    Baxter, L.2    Jain, R.3
  • 127
    • 0031039632 scopus 로고    scopus 로고
    • Interstitial fluid pressure in intracranial tumors in patients and in rodents
    • Y. Boucher, J. Salehi, B. Witwer, and R. Jain, Interstitial fluid pressure in intracranial tumors in patients and in rodents. Br. J. Cancer 75:829 (1997).
    • (1997) Br. J. Cancer , vol.75 , pp. 829
    • Boucher, Y.1    Salehi, J.2    Witwer, B.3    Jain, R.4
  • 129
    • 27144541820 scopus 로고    scopus 로고
    • Differential growth and instability in elastic shells
    • A. Goriely and M. B. Amar, Differential growth and instability in elastic shells. Phys. Rev. Lett. 94:198103 (2005).
    • (2005) Phys. Rev. Lett , vol.94 , pp. 198103
    • Goriely, A.1    Amar, M.B.2
  • 130
    • 84914448406 scopus 로고
    • MedCom-Press, New York
    • J. Dunphy, Wound healing (MedCom-Press, New York, 1978).
    • (1978) Wound healing
    • Dunphy, J.1
  • 131
    • 0034696764 scopus 로고    scopus 로고
    • Evolving mechanisms of morphogenesis: On the interplay between differential adhesion and cell differentiation
    • P. Hogeweg, Evolving mechanisms of morphogenesis: On the interplay between differential adhesion and cell differentiation. J. Theor. Biol. 203:317 (2000).
    • (2000) J. Theor. Biol , vol.203 , pp. 317
    • Hogeweg, P.1
  • 132
    • 34249890282 scopus 로고    scopus 로고
    • Emergence of cell migration and aggregation strategies in a simulated evolutionary process
    • D. Drasdo and M. Kruspe. Emergence of cell migration and aggregation strategies in a simulated evolutionary process. Adv. Complex Syst. 8 (2005).
    • (2005) Adv. Complex Syst , vol.8
    • Drasdo, D.1    Kruspe, M.2
  • 133
    • 3042594418 scopus 로고    scopus 로고
    • A mathematical model of the effects of hypoxia on the cell-cycle of normal and cancer cells
    • T. Alarcon. H. Byrne, and P. Maini, A mathematical model of the effects of hypoxia on the cell-cycle of normal and cancer cells. J. Theor. Biol. 229:395 (2004).
    • (2004) J. Theor. Biol , vol.229 , pp. 395
    • Alarcon, T.1    Byrne, H.2    Maini, P.3
  • 134
    • 84988072581 scopus 로고
    • A model for density-dependent growth of anchorage-dependent mammalian cells
    • K. Frame and W. Hu, A model for density-dependent growth of anchorage-dependent mammalian cells. Biotechnol. Bioengineering 32:1062 (1988).
    • (1988) Biotechnol. Bioengineering , vol.32 , pp. 1062
    • Frame, K.1    Hu, W.2
  • 136
    • 11144315531 scopus 로고    scopus 로고
    • Vessel maturation effects on tumour growth: Validation of a computer model in implanted human ovarian carcinoma spheroids
    • L. Arakelyan, Y. Merbl, and Z. Agur, Vessel maturation effects on tumour growth: Validation of a computer model in implanted human ovarian carcinoma spheroids. Eur. J. Cancer 41:159 (2005).
    • (2005) Eur. J. Cancer , vol.41 , pp. 159
    • Arakelyan, L.1    Merbl, Y.2    Agur, Z.3
  • 137
    • 30344455929 scopus 로고    scopus 로고
    • Optimisation of time-scheduled regimen for anti-cancer drug infusion
    • C. Basdevant, J. Clairambault, and F. Levi, Optimisation of time-scheduled regimen for anti-cancer drug infusion. Math. Modelling Numerical Anal. 39:1069 (2005).
    • (2005) Math. Modelling Numerical Anal , vol.39 , pp. 1069
    • Basdevant, C.1    Clairambault, J.2    Levi, F.3
  • 138
    • 13244297069 scopus 로고    scopus 로고
    • B. Ribba, K. Marron, Z. Agur, T. A. T, and P. Maini, A mathematical model of doxorubicin treatment efficacy for non-hodgkin's lymphoma: Investigation of the current protocol through theoretical modelling results. Bull. Math. Biol. 67:79 (2005).
    • B. Ribba, K. Marron, Z. Agur, T. A. T, and P. Maini, A mathematical model of doxorubicin treatment efficacy for non-hodgkin's lymphoma: Investigation of the current protocol through theoretical modelling results. Bull. Math. Biol. 67:79 (2005).
  • 139
    • 33646249607 scopus 로고    scopus 로고
    • A multiscale mathematical model of cancer and its use in analyzing irradiation therapies
    • B. Ribba, T. Colin, and S. Schnell, A multiscale mathematical model of cancer and its use in analyzing irradiation therapies. Theor. Biol. Med. Model 3:7 (2006).
    • (2006) Theor. Biol. Med. Model , vol.3 , pp. 7
    • Ribba, B.1    Colin, T.2    Schnell, S.3
  • 143
    • 0001245501 scopus 로고
    • Nonlinear dynamics of stiff polymers
    • R. Goldstein and S. Langer, Nonlinear dynamics of stiff polymers. Phys. Rev. Lett. 75:1094 (1995).
    • (1995) Phys. Rev. Lett , vol.75 , pp. 1094
    • Goldstein, R.1    Langer, S.2
  • 145
    • 0000285519 scopus 로고
    • Adhesion of vesicles in two dimensions
    • U. Seifert, Adhesion of vesicles in two dimensions. Phys. Rev. A 43:6803 (1991).
    • (1991) Phys. Rev. A , vol.43 , pp. 6803
    • Seifert, U.1
  • 146
    • 0024000989 scopus 로고
    • Pattern selection in fingered growth, phenomena
    • D. Kessler, J. Koplik, and H. Levine, Pattern selection in fingered growth, phenomena. Adv. Phys. 37:255 (1988).
    • (1988) Adv. Phys , vol.37 , pp. 255
    • Kessler, D.1    Koplik, J.2    Levine, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.